ES8202012A1 - Un procedimiento para la preparacion de derivados de campto-tecina - Google Patents

Un procedimiento para la preparacion de derivados de campto-tecina

Info

Publication number
ES8202012A1
ES8202012A1 ES499987A ES499987A ES8202012A1 ES 8202012 A1 ES8202012 A1 ES 8202012A1 ES 499987 A ES499987 A ES 499987A ES 499987 A ES499987 A ES 499987A ES 8202012 A1 ES8202012 A1 ES 8202012A1
Authority
ES
Spain
Prior art keywords
group
derivatives
procedure
preparation
tecina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES499987A
Other languages
English (en)
Other versions
ES499987A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yakult Honsha Co Ltd
Original Assignee
Yakult Honsha Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8641079A external-priority patent/JPS5612391A/ja
Priority claimed from JP8641379A external-priority patent/JPS5612394A/ja
Priority claimed from JP8641279A external-priority patent/JPS5612393A/ja
Priority claimed from JP8641179A external-priority patent/JPS5612392A/ja
Application filed by Yakult Honsha Co Ltd filed Critical Yakult Honsha Co Ltd
Publication of ES499987A0 publication Critical patent/ES499987A0/es
Publication of ES8202012A1 publication Critical patent/ES8202012A1/es
Expired legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE CAMPTOTECINA DE FORMULA GENERAL (I), DONDE Y'' REPRESENTA OH O UN GRUPO OR3, DONDE R3 ES UN GRUPO ALQUILO O ACILO, Y Z REPRESENTA H O UN GRUPO ACILO, ASI COMO SUS SALES DE METALES ALCALINOS SOLUBLES EN AGUA. CONSISTE EN HACER REACCIONAR LA CAMPTOTECINA CON ACIDO SULFURICO Y UN PERSULFATO EN UN MEDIO ACUOSO QUE CONTIENE UN ION METALICO DE TRANSICION, Y OPCIONALMENTE TRATAR LA 5-HIDROXICAMPTOTECINA RESULTANTE CON UN AGENTE ALQUILANTE O ACILANTE PARA CONVERTIR EL GRUPO 5-HIDROXI EN UN GRUPO 5-ALCOXI O 5-ACILOXI CON O SIN ACILACION SIMULTANEA DEL GRUPO 20-HIDROXI.
ES499987A 1979-07-10 1981-03-02 Un procedimiento para la preparacion de derivados de campto-tecina Expired ES8202012A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP8641079A JPS5612391A (en) 1979-07-10 1979-07-10 Novel camptothecin derivative and its preparaion
JP8641379A JPS5612394A (en) 1979-07-10 1979-07-10 Novel camptothecin derivative
JP8641279A JPS5612393A (en) 1979-07-10 1979-07-10 Novel camptothecin derivative
JP8641179A JPS5612392A (en) 1979-07-10 1979-07-10 Novel camptothecin derivative and its preparation

Publications (2)

Publication Number Publication Date
ES499987A0 ES499987A0 (es) 1982-01-01
ES8202012A1 true ES8202012A1 (es) 1982-01-01

Family

ID=27467257

Family Applications (3)

Application Number Title Priority Date Filing Date
ES493287A Expired ES8105735A1 (es) 1979-07-10 1980-07-10 Un procedimiento para la preparacion de derivados de campto tecina.
ES499987A Expired ES8202012A1 (es) 1979-07-10 1981-03-02 Un procedimiento para la preparacion de derivados de campto-tecina
ES499986A Granted ES499986A0 (es) 1979-07-10 1981-03-02 Un procedimiento para la preparacion de derivados de campto-tecina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES493287A Expired ES8105735A1 (es) 1979-07-10 1980-07-10 Un procedimiento para la preparacion de derivados de campto tecina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES499986A Granted ES499986A0 (es) 1979-07-10 1981-03-02 Un procedimiento para la preparacion de derivados de campto-tecina

Country Status (1)

Country Link
ES (3) ES8105735A1 (es)

Also Published As

Publication number Publication date
ES8202011A1 (es) 1982-01-01
ES493287A0 (es) 1981-06-16
ES499987A0 (es) 1982-01-01
ES499986A0 (es) 1982-01-01
ES8105735A1 (es) 1981-06-16

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