DE68912745T2 - Herstellung von optisch aktiven 2-Oxoimidazolidin-derivaten. - Google Patents
Herstellung von optisch aktiven 2-Oxoimidazolidin-derivaten.Info
- Publication number
- DE68912745T2 DE68912745T2 DE89312965T DE68912745T DE68912745T2 DE 68912745 T2 DE68912745 T2 DE 68912745T2 DE 89312965 T DE89312965 T DE 89312965T DE 68912745 T DE68912745 T DE 68912745T DE 68912745 T2 DE68912745 T2 DE 68912745T2
- Authority
- DE
- Germany
- Prior art keywords
- optically active
- oxoimidazolidine
- production
- group
- chem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- YAMHXTCMCPHKLN-UHFFFAOYSA-N imidazolidin-2-one Chemical class O=C1NCCN1 YAMHXTCMCPHKLN-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63318745A JPH0645603B2 (ja) | 1988-12-16 | 1988-12-16 | 光学活性２‐オキソイミダゾリジン誘導体の製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE68912745D1 DE68912745D1 (de) | 1994-03-10 |
| DE68912745T2 true DE68912745T2 (de) | 1994-05-11 |
Family
ID=18102470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE89312965T Expired - Lifetime DE68912745T2 (de) | 1988-12-16 | 1989-12-12 | Herstellung von optisch aktiven 2-Oxoimidazolidin-derivaten. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5013845A (de) |
| EP (1) | EP0373881B1 (de) |
| JP (1) | JPH0645603B2 (de) |
| KR (1) | KR950009364B1 (de) |
| CN (1) | CN1032308C (de) |
| AT (1) | ATE100817T1 (de) |
| AU (1) | AU622959B2 (de) |
| CA (1) | CA2004606C (de) |
| DE (1) | DE68912745T2 (de) |
| DK (1) | DK174701B1 (de) |
| ES (1) | ES2062044T3 (de) |
| FI (1) | FI97133C (de) |
| HK (1) | HK34195A (de) |
| HU (1) | HU203730B (de) |
| IE (1) | IE64315B1 (de) |
| IL (1) | IL92456A0 (de) |
| SG (1) | SG4795G (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104513292A (zh) * | 2013-09-29 | 2015-04-15 | 山东新时代药业有限公司 | 一种雷米普利的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5788165A (en) * | 1980-11-21 | 1982-06-01 | Tanabe Seiyaku Co Ltd | 2-oxoimidazolidine-4-carboxylic acid derivative and its preparation |
| JPS6058233B2 (ja) * | 1982-05-24 | 1985-12-19 | 田辺製薬株式会社 | ２−オキソイミダゾリジン誘導体及びその製法 |
| JPS6058233A (ja) * | 1983-08-11 | 1985-04-04 | ザ・アプジヨン・カンパニー | 滅菌懸濁液及び溶液の保持及び混合装置 |
-
1988
- 1988-12-16 JP JP63318745A patent/JPH0645603B2/ja not_active Expired - Lifetime
-
1989
- 1989-11-27 IL IL92456A patent/IL92456A0/xx unknown
- 1989-12-04 US US07/445,060 patent/US5013845A/en not_active Expired - Lifetime
- 1989-12-04 FI FI895795A patent/FI97133C/fi active IP Right Grant
- 1989-12-05 CA CA002004606A patent/CA2004606C/en not_active Expired - Lifetime
- 1989-12-05 CN CN89109175A patent/CN1032308C/zh not_active Expired - Lifetime
- 1989-12-12 DE DE89312965T patent/DE68912745T2/de not_active Expired - Lifetime
- 1989-12-12 AT AT89312965T patent/ATE100817T1/de not_active IP Right Cessation
- 1989-12-12 AU AU46195/89A patent/AU622959B2/en not_active Expired
- 1989-12-12 EP EP89312965A patent/EP0373881B1/de not_active Expired - Lifetime
- 1989-12-12 ES ES89312965T patent/ES2062044T3/es not_active Expired - Lifetime
- 1989-12-14 IE IE400489A patent/IE64315B1/en not_active IP Right Cessation
- 1989-12-15 HU HU896640A patent/HU203730B/hu unknown
- 1989-12-15 KR KR1019890018658A patent/KR950009364B1/ko not_active IP Right Cessation
- 1989-12-15 DK DK198906382A patent/DK174701B1/da not_active IP Right Cessation
-
1995
- 1995-01-13 SG SG4795A patent/SG4795G/en unknown
- 1995-03-09 HK HK34195A patent/HK34195A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HU203730B (en) | 1991-09-30 |
| KR900009603A (ko) | 1990-07-05 |
| AU622959B2 (en) | 1992-04-30 |
| CA2004606A1 (en) | 1990-06-16 |
| FI97133B (fi) | 1996-07-15 |
| JPH0645603B2 (ja) | 1994-06-15 |
| HK34195A (en) | 1995-03-17 |
| ES2062044T3 (es) | 1994-12-16 |
| IL92456A0 (en) | 1990-08-31 |
| CN1032308C (zh) | 1996-07-17 |
| ATE100817T1 (de) | 1994-02-15 |
| CA2004606C (en) | 1997-01-07 |
| EP0373881B1 (de) | 1994-01-26 |
| SG4795G (en) | 1995-06-16 |
| AU4619589A (en) | 1990-06-21 |
| DK638289A (da) | 1990-06-17 |
| DK638289D0 (da) | 1989-12-15 |
| EP0373881A2 (de) | 1990-06-20 |
| HU896640D0 (en) | 1990-02-28 |
| IE894004L (en) | 1990-06-16 |
| CN1043705A (zh) | 1990-07-11 |
| DK174701B1 (da) | 2003-09-29 |
| DE68912745D1 (de) | 1994-03-10 |
| IE64315B1 (en) | 1995-07-26 |
| HUT52064A (en) | 1990-06-28 |
| KR950009364B1 (ko) | 1995-08-21 |
| US5013845A (en) | 1991-05-07 |
| FI97133C (fi) | 1996-10-25 |
| EP0373881A3 (en) | 1990-08-16 |
| JPH02164869A (ja) | 1990-06-25 |
| FI895795A0 (fi) | 1989-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |