ATE75739T1 - Verfahren zur herstellung von dibenzothiepinderivaten. - Google Patents
Verfahren zur herstellung von dibenzothiepinderivaten.Info
- Publication number
- ATE75739T1 ATE75739T1 AT87308655T AT87308655T ATE75739T1 AT E75739 T1 ATE75739 T1 AT E75739T1 AT 87308655 T AT87308655 T AT 87308655T AT 87308655 T AT87308655 T AT 87308655T AT E75739 T1 ATE75739 T1 AT E75739T1
- Authority
- AT
- Austria
- Prior art keywords
- dibenzothiopine
- derivatives
- production
- derivative
- converted
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- MUXFZBHBYYYLTH-UHFFFAOYSA-N Zaltoprofen Chemical compound O=C1CC2=CC(C(C(O)=O)C)=CC=C2SC2=CC=CC=C21 MUXFZBHBYYYLTH-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000008510 dibenzothiepins Chemical class 0.000 abstract 1
- -1 haloketone compound Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- KRIOVPPHQSLHCZ-UHFFFAOYSA-N propiophenone Chemical class CCC(=O)C1=CC=CC=C1 KRIOVPPHQSLHCZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
- 238000006798 ring closing metathesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP87308655A EP0309626B1 (de) | 1987-09-30 | 1987-09-30 | Verfahren zur Herstellung von Dibenzothiepin-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE75739T1 true ATE75739T1 (de) | 1992-05-15 |
Family
ID=8198054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87308655T ATE75739T1 (de) | 1987-09-30 | 1987-09-30 | Verfahren zur herstellung von dibenzothiepinderivaten. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0309626B1 (de) |
| AT (1) | ATE75739T1 (de) |
| AU (1) | AU590450B2 (de) |
| DE (1) | DE3778896D1 (de) |
| ES (1) | ES2032834T3 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996022289A1 (en) * | 1995-01-20 | 1996-07-25 | Nippon Chemiphar Co., Ltd. | Process for producing dibenzothiepin derivative |
| AU3952497A (en) * | 1996-08-22 | 1998-03-06 | Nippon Chemiphar Co. Ltd. | Process for preparing 2-(10,11-dihydro-10-oxodibenzo{b,f}thiepin-2-yl)propionic acid and intermediates therefor |
| KR100730767B1 (ko) * | 2001-12-06 | 2007-06-21 | 코오롱생명과학 주식회사 | 디벤조티에핀 유도체의 신규 제조방법 |
| CN100462362C (zh) * | 2005-12-20 | 2009-02-18 | 常州市康瑞化工有限公司 | 2－(10－氧代－10,11二氢二苯并[b,f]硫杂－2－基)丙酸的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5553282A (en) * | 1978-10-17 | 1980-04-18 | Nippon Chemiphar Co Ltd | Dibenzothiepin derivative and its preparation |
| JPS57106678A (en) * | 1980-12-23 | 1982-07-02 | Nippon Chemiphar Co Ltd | Preparation of dibenzothiepinpropionic acid derivative |
| JPS58113168A (ja) * | 1981-12-28 | 1983-07-05 | Fuji Photo Film Co Ltd | ５−（１−カルボキシエチル）−２−フエニルチオフエニル酢酸の製造法 |
-
1987
- 1987-09-30 AT AT87308655T patent/ATE75739T1/de not_active IP Right Cessation
- 1987-09-30 DE DE8787308655T patent/DE3778896D1/de not_active Expired - Fee Related
- 1987-09-30 ES ES198787308655T patent/ES2032834T3/es not_active Expired - Lifetime
- 1987-09-30 EP EP87308655A patent/EP0309626B1/de not_active Expired
- 1987-10-01 AU AU79262/87A patent/AU590450B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU590450B2 (en) | 1989-11-02 |
| AU7926287A (en) | 1989-04-06 |
| ES2032834T3 (es) | 1993-03-01 |
| DE3778896D1 (de) | 1992-06-11 |
| EP0309626A1 (de) | 1989-04-05 |
| EP0309626B1 (de) | 1992-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO874350D0 (no) | Fremgangsmaate for fremstilling av antibakterielle forbindelser. | |
| DE69532634D1 (de) | Zwischenprodukte für die herstellung von pharmazeutischem camptothecin | |
| DE69120500D1 (de) | Azasteroide zur Behandlung prostatischer Hypertrophie, ihre Herstellung und Verwendung | |
| DE69327567D1 (de) | Verfahren zur Herstellung von Alanylglutamin | |
| FI101226B1 (fi) | Menetelmä lääkeaineena käyttökelpoisten 2-[2-(karbonyyli)pyrrolidin-4-yylitio]-6-(1-hydroksietyyli)-1-metyylikarbapen-2-eemi-3-karboksyylihappojohdannaisten valmistamiseksi | |
| DE3767351D1 (de) | Sialosylceramide und verfahren zu deren herstellung. | |
| DE69106003D1 (de) | Verfahren und zwischenprodukte zur herstellung von azabicyclo[2.2.2]octan-3-iminen. | |
| ES543154A0 (es) | Metodo de preparar un derivado de acido b-carbolin-3-carbo- xilico | |
| ATE107295T1 (de) | Verfahren zur herstellung von 1,5-benzothiazepin- derivaten. | |
| ATE75739T1 (de) | Verfahren zur herstellung von dibenzothiepinderivaten. | |
| DE3854109D1 (de) | Verfahren zur herstellung von chinolincarbonsäuren. | |
| ATE107288T1 (de) | Verfahren zur herstellung von o- carboxyarylimidazolinone. | |
| DE3889772D1 (de) | Verfahren zur Herstellung von 3,3-Diarylacrylsäureamiden. | |
| ATE115567T1 (de) | Verfahren zur herstellung von halogensulfonyl- substituierten pyridinen. | |
| ATE46322T1 (de) | Verfahren zur herstellung von bestatin-derivaten und deren zwischenprodukte. | |
| DE58903385D1 (de) | Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung. | |
| DE69127960D1 (de) | Verfahren zur Herstellung von (S)-vinyl- und (S)-allenyl-Gaba | |
| DE3777464D1 (de) | Fluorine enthaltende vitamin-d3-derivate und verfahren zu ihrer herstellung. | |
| ATE165824T1 (de) | Verfahren zur herstellung von 2-perfluoroalkyl-3- oxazolin-5-one | |
| DE68914309D1 (de) | Verfahren zur Herstellung von Phtalazinessigsäure-Ester-Derivaten und ein neues Zwischenprodukt. | |
| DE3884518D1 (de) | Naphthothiazepin-derivate und verfahren zu ihrer herstellung. | |
| PT84517B (pt) | Processo aperfeicoado para a preparacao de di-hidro-1h-pirrolizina-3,5-(2h,6h)-biona | |
| ATE179417T1 (de) | Glyceraldehyd-3-pentanid und verfahren zu ihrer herstellung | |
| ATE46315T1 (de) | Verfahren zur herstellung optisch aktiver chinonderivate. | |
| ATE57934T1 (de) | Verfahren zur herstellung von griseolinsaeurederivaten. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |