DE68909777T2 - Verfahren zur immobilisierung eines proteins auf ein polymer und so erzeugte membran. - Google Patents

Verfahren zur immobilisierung eines proteins auf ein polymer und so erzeugte membran.

Info

Publication number
DE68909777T2
DE68909777T2 DE89902500T DE68909777T DE68909777T2 DE 68909777 T2 DE68909777 T2 DE 68909777T2 DE 89902500 T DE89902500 T DE 89902500T DE 68909777 T DE68909777 T DE 68909777T DE 68909777 T2 DE68909777 T2 DE 68909777T2
Authority
DE
Germany
Prior art keywords
pct
anode
electrode
sec
terminals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89902500T
Other languages
English (en)
Other versions
DE68909777D1 (de
Inventor
Henrik Ege
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE68909777D1 publication Critical patent/DE68909777D1/de
Application granted granted Critical
Publication of DE68909777T2 publication Critical patent/DE68909777T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/002Electrode membranes
    • C12Q1/003Functionalisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/817Enzyme or microbe electrode

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
DE89902500T 1988-02-05 1989-02-03 Verfahren zur immobilisierung eines proteins auf ein polymer und so erzeugte membran. Expired - Fee Related DE68909777T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK061488A DK61488D0 (da) 1988-02-05 1988-02-05 Fremgangsmaade

Publications (2)

Publication Number Publication Date
DE68909777D1 DE68909777D1 (de) 1993-11-11
DE68909777T2 true DE68909777T2 (de) 1994-03-10

Family

ID=8095570

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89902500T Expired - Fee Related DE68909777T2 (de) 1988-02-05 1989-02-03 Verfahren zur immobilisierung eines proteins auf ein polymer und so erzeugte membran.

Country Status (9)

Country Link
US (1) US5223124A (de)
EP (1) EP0397784B1 (de)
JP (1) JP2790348B2 (de)
AT (1) ATE95562T1 (de)
AU (1) AU613157B2 (de)
CA (1) CA1319633C (de)
DE (1) DE68909777T2 (de)
DK (2) DK61488D0 (de)
WO (1) WO1989007139A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8909613D0 (en) * 1989-04-27 1989-06-14 Pickup John C Glucose-sensing electrode
DE4027728A1 (de) * 1990-08-31 1992-03-05 Bayer Ag Immobilisierung von organischen makromolekuelen oder biopolymeren in einer polymermembran
US5354449A (en) * 1991-01-10 1994-10-11 Band David M pH electrode
EP0643833A1 (de) * 1991-06-04 1995-03-22 FISONS plc Analysevorrichtung
AT401653B (de) * 1994-10-05 1996-11-25 Avl Verbrennungskraft Messtech Verfahren zur immobilisierung biologischer komponenten in einer polymermatrix sowie biosensoren unter verwendung derartiger immobilisate
US5611900A (en) * 1995-07-20 1997-03-18 Michigan State University Microbiosensor used in-situ
FR2754707B1 (fr) * 1996-10-22 1999-01-08 Philippe Korsec Aiguille d'acupuncture chauffante
US6299980B1 (en) 1998-09-29 2001-10-09 Medtronic Ave, Inc. One step lubricious coating
US6379691B1 (en) 1998-09-29 2002-04-30 Medtronic/Ave, Inc. Uses for medical devices having a lubricious, nitric oxide-releasing coating
US6833260B1 (en) 1999-10-08 2004-12-21 Protein Scientific, Inc. Lactose hydrolysis
US6592730B1 (en) * 2000-02-07 2003-07-15 Steris Inc. Durable carbon electrode
US6793632B2 (en) * 2001-06-12 2004-09-21 Lifescan, Inc. Percutaneous biological fluid constituent sampling and measurement devices and methods
US6501976B1 (en) * 2001-06-12 2002-12-31 Lifescan, Inc. Percutaneous biological fluid sampling and analyte measurement devices and methods
US7335400B2 (en) * 2001-07-24 2008-02-26 University Of Pittsburgh Irreversible immobilization of enzymes into polyurethane coatings
US20030135166A1 (en) * 2001-09-28 2003-07-17 Gonnelli Robert R. Switchable microneedle arrays and systems and methods relating to same
US7101472B2 (en) * 2002-03-13 2006-09-05 The Charles Stark Draper Laboratory, Inc. Microfluidic ion-selective electrode sensor system
US7407570B2 (en) * 2002-03-13 2008-08-05 The Charles Stark Draper Laboratory, Inc. Disposable, self-administered electrolyte test
US20070088208A1 (en) * 2003-02-17 2007-04-19 Mikito Yasuzawa Linear device
WO2005051183A1 (en) * 2003-11-25 2005-06-09 Novo Nordisk A/S A needle sensor and a mechanism for inserting the needle sensor through the skin
US7283866B2 (en) * 2004-05-18 2007-10-16 Hatch Ltd Needle having multiple electrodes
EP1782062A4 (de) * 2004-08-24 2010-09-08 Univ South Florida Epoxidverbesserte polymermembran zur erhöhung der haltbarkeit von biosensoren
US20070111196A1 (en) * 2005-08-19 2007-05-17 Javier Alarcon Sterilization of Biosensors
US9044178B2 (en) 2007-08-30 2015-06-02 Pepex Biomedical, Llc Electrochemical sensor and method for manufacturing
WO2009032760A2 (en) 2007-08-30 2009-03-12 Pepex Biomedical Llc Electrochmical sensor and method for manufacturing
EP2254458A1 (de) 2008-02-04 2010-12-01 Bayer HealthCare, LLC Analytensensoren auf halbleiterbasis und verfahren
CA2735675C (en) 2008-09-19 2017-02-14 Bayer Healthcare Llc Electrochemical devices with enhanced electrochemical activity and manufacturing methods thereof
US9173597B2 (en) * 2008-09-19 2015-11-03 Bayer Healthcare Llc Analyte sensors, systems, testing apparatus and manufacturing methods
WO2010056878A2 (en) 2008-11-14 2010-05-20 Pepex Biomedical, Llc Electrochemical sensor module
US8951377B2 (en) 2008-11-14 2015-02-10 Pepex Biomedical, Inc. Manufacturing electrochemical sensor module
US9504162B2 (en) 2011-05-20 2016-11-22 Pepex Biomedical, Inc. Manufacturing electrochemical sensor modules
CN102551674B (zh) * 2012-01-30 2015-04-22 东南大学 具有生物检测功能的针头及其应用
BR112015012958B1 (pt) 2012-12-03 2022-03-15 Pepex Biomedical, Inc Módulo sensor para detectar um analito em uma amostra de sangue
EP3152559B1 (de) 2014-06-04 2020-12-02 Pepex Biomedical, Inc. Elektrochemische sensoren hergestellt mit erweiterter drucktechnologie

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237229A (en) * 1975-06-10 1980-12-02 W. R. Grace & Co. Immobilization of biological material with polyurethane polymers
US4094744A (en) * 1976-11-18 1978-06-13 W. R. Grace & Co. Water-dispersible protein/polyurethane reaction product
US4407957A (en) * 1981-03-13 1983-10-04 Damon Corporation Reversible microencapsulation of a core material
DE3617875C2 (de) * 1985-06-28 1993-10-14 Hitachi Plant Eng & Constr Co Verfahren zum Immobilisieren von Mikroorganismen
GB8522834D0 (en) * 1985-09-16 1985-10-23 Ici Plc Sensor
DE3540333A1 (de) * 1985-11-14 1987-05-21 Bayer Ag Verfahren zur immobilisierung von biologischem material, teilchenfoermige koagulate enthaltend ein immobilisiertes biologisches material und ihre verwendung als katalysator
US4871716A (en) * 1986-02-04 1989-10-03 University Of Florida Magnetically responsive, hydrophilic microspheres for incorporation of therapeutic substances and methods of preparation thereof
DE3705687A1 (de) * 1987-02-23 1988-09-01 Boehringer Mannheim Gmbh Polyurethanmodifizierte enzyme

Also Published As

Publication number Publication date
EP0397784A1 (de) 1990-11-22
DK61488D0 (da) 1988-02-05
JP2790348B2 (ja) 1998-08-27
DE68909777D1 (de) 1993-11-11
AU3064689A (en) 1989-08-25
DK187090A (da) 1990-08-06
ATE95562T1 (de) 1993-10-15
WO1989007139A1 (en) 1989-08-10
EP0397784B1 (de) 1993-10-06
DK187090D0 (da) 1990-08-06
AU613157B2 (en) 1991-07-25
CA1319633C (en) 1993-06-29
US5223124A (en) 1993-06-29
JPH03503480A (ja) 1991-08-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee