DE68905216T2 - Hetera-aliphatische carboxamide. - Google Patents

Hetera-aliphatische carboxamide.

Info

Publication number
DE68905216T2
DE68905216T2 DE8989303623T DE68905216T DE68905216T2 DE 68905216 T2 DE68905216 T2 DE 68905216T2 DE 8989303623 T DE8989303623 T DE 8989303623T DE 68905216 T DE68905216 T DE 68905216T DE 68905216 T2 DE68905216 T2 DE 68905216T2
Authority
DE
Germany
Prior art keywords
formula
ylmethyl
hydrogen
compound
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989303623T
Other languages
German (de)
English (en)
Other versions
DE68905216D1 (de
Inventor
Victor Giulio Matassa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeneca Inc
Original Assignee
ICI Americas Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ICI Americas Inc filed Critical ICI Americas Inc
Application granted granted Critical
Publication of DE68905216D1 publication Critical patent/DE68905216D1/de
Publication of DE68905216T2 publication Critical patent/DE68905216T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE8989303623T 1988-04-14 1989-04-12 Hetera-aliphatische carboxamide. Expired - Fee Related DE68905216T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18133488A 1988-04-14 1988-04-14

Publications (2)

Publication Number Publication Date
DE68905216D1 DE68905216D1 (de) 1993-04-15
DE68905216T2 true DE68905216T2 (de) 1993-06-17

Family

ID=22663845

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989303623T Expired - Fee Related DE68905216T2 (de) 1988-04-14 1989-04-12 Hetera-aliphatische carboxamide.

Country Status (23)

Country Link
EP (1) EP0337766B1 (enExample)
JP (1) JP2740250B2 (enExample)
KR (1) KR890016016A (enExample)
CN (1) CN1037895A (enExample)
AT (1) ATE86612T1 (enExample)
AU (1) AU622649B2 (enExample)
CA (1) CA1334197C (enExample)
DD (1) DD286581A5 (enExample)
DE (1) DE68905216T2 (enExample)
DK (1) DK176089A (enExample)
ES (1) ES2053983T3 (enExample)
FI (1) FI891764A7 (enExample)
GB (1) GB8906032D0 (enExample)
GR (1) GR3007302T3 (enExample)
HU (1) HUT54995A (enExample)
IE (1) IE63209B1 (enExample)
IL (1) IL89925A0 (enExample)
MW (1) MW2189A1 (enExample)
NO (1) NO891501L (enExample)
NZ (1) NZ228722A (enExample)
PT (1) PT90269B (enExample)
ZA (1) ZA892637B (enExample)
ZM (1) ZM1689A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8927981D0 (en) * 1989-12-11 1990-02-14 Ici Plc Carbamoyl derivative
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents
EP0539329A1 (de) * 1991-10-25 1993-04-28 Ciba-Geigy Ag Acetylen-Verbindungen, verwendbar als Leukotrien-Antagonisten
EP0539330B1 (de) * 1991-10-25 1995-05-17 Ciba-Geigy Ag Verfahren zur Herstellung substituierter Indole
KR100436812B1 (ko) * 1995-01-06 2004-08-31 도레이 가부시끼가이샤 벤젠축합헤테로환유도체및그유도체를유효성분으로함유하는의약조성물
CA2322162A1 (en) * 1998-02-25 1999-09-02 Genetics Institute, Llc Inhibitors of phospholipase enzymes
US6500853B1 (en) 1998-02-28 2002-12-31 Genetics Institute, Llc Inhibitors of phospholipase enzymes
US6984735B2 (en) 2001-12-03 2006-01-10 Wyeth Process for making an aldehyde
US7713964B2 (en) 2001-12-03 2010-05-11 Wyeth Llc Methods for treating asthmatic conditions
US7605156B2 (en) 2001-12-03 2009-10-20 Wyeth Methods for the use of inhibitors of cytosolic phospholipase A2
US6635771B2 (en) 2001-12-03 2003-10-21 Wyeth N-benzhydryl indole compounds
US6797708B2 (en) 2001-12-03 2004-09-28 Wyeth Inhibitors of cytosolic phospholipase A2
US7101875B2 (en) 2001-12-03 2006-09-05 Wyeth Methods for treating arthritic disorders
TW200718687A (en) 2005-05-27 2007-05-16 Wyeth Corp Inhibitors of cytosolic phospholipase A2
TW201309670A (zh) 2011-01-25 2013-03-01 Kissei Pharmaceutical 吲哚衍生物或其藥理學上容許之鹽

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides

Also Published As

Publication number Publication date
FI891764A7 (fi) 1989-10-15
FI891764A0 (fi) 1989-04-13
AU3177089A (en) 1989-10-19
PT90269B (pt) 1994-07-29
HUT54995A (en) 1991-04-29
DK176089A (da) 1989-10-15
NZ228722A (en) 1991-08-27
ATE86612T1 (de) 1993-03-15
DK176089D0 (da) 1989-04-12
CA1334197C (en) 1995-01-31
ES2053983T3 (es) 1994-08-01
MW2189A1 (en) 1989-12-13
DE68905216D1 (de) 1993-04-15
EP0337766A1 (en) 1989-10-18
NO891501L (no) 1989-10-16
KR890016016A (ko) 1989-11-28
CN1037895A (zh) 1989-12-13
ZM1689A1 (en) 1990-01-26
IE63209B1 (en) 1995-04-05
EP0337766B1 (en) 1993-03-10
GB8906032D0 (en) 1989-04-26
GR3007302T3 (enExample) 1993-07-30
PT90269A (pt) 1989-11-10
IL89925A0 (en) 1989-12-15
AU622649B2 (en) 1992-04-16
JP2740250B2 (ja) 1998-04-15
ZA892637B (en) 1989-12-27
NO891501D0 (no) 1989-04-12
DD286581A5 (de) 1991-01-31
JPH01311063A (ja) 1989-12-15
IE891188L (en) 1989-10-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee