DE68903907T2 - Cyclisches peptid, seine herstellung und seine verwendung zur behandlung von cardiovasculaeren stoerungen. - Google Patents

Cyclisches peptid, seine herstellung und seine verwendung zur behandlung von cardiovasculaeren stoerungen.

Info

Publication number
DE68903907T2
DE68903907T2 DE8989308901T DE68903907T DE68903907T2 DE 68903907 T2 DE68903907 T2 DE 68903907T2 DE 8989308901 T DE8989308901 T DE 8989308901T DE 68903907 T DE68903907 T DE 68903907T DE 68903907 T2 DE68903907 T2 DE 68903907T2
Authority
DE
Germany
Prior art keywords
compound
leualacin
measured
hapsidospora
irregularis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989308901T
Other languages
German (de)
English (en)
Other versions
DE68903907D1 (de
Inventor
Kouhei C O Sankyo Compa Furuya
Kiyoshi C O Sankyo Comp Hamano
Takeshi C O Sankyo Co Kagasaki
Takeshi C O Sankyo C Kinoshita
Masaaki C O Sankyo Co Miyamoto
Kazuhiko C O Sankyo Co Tanzawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of DE68903907D1 publication Critical patent/DE68903907D1/de
Application granted granted Critical
Publication of DE68903907T2 publication Critical patent/DE68903907T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8989308901T 1988-09-05 1989-09-01 Cyclisches peptid, seine herstellung und seine verwendung zur behandlung von cardiovasculaeren stoerungen. Expired - Fee Related DE68903907T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22196088 1988-09-05

Publications (2)

Publication Number Publication Date
DE68903907D1 DE68903907D1 (de) 1993-01-28
DE68903907T2 true DE68903907T2 (de) 1993-06-09

Family

ID=16774855

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989308901T Expired - Fee Related DE68903907T2 (de) 1988-09-05 1989-09-01 Cyclisches peptid, seine herstellung und seine verwendung zur behandlung von cardiovasculaeren stoerungen.

Country Status (6)

Country Link
US (1) US5112807A (enExample)
EP (1) EP0358418B1 (enExample)
AT (1) ATE83480T1 (enExample)
DE (1) DE68903907T2 (enExample)
ES (1) ES2054011T3 (enExample)
GR (1) GR3007079T3 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9302046D0 (en) * 1993-02-03 1993-03-24 Pharma Mar Sa Antiumoral compound-v
DE4310643A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
US5461070A (en) * 1994-08-29 1995-10-24 The Regents Of The University Of California Anti-flammatory method using indole alkaloids
IL117302A (en) * 1995-03-07 2005-03-20 Univ Hawaii Cryptophycin derivatives, methods for the production thereof and pharmaceutical compositions containing the same
JP5647146B2 (ja) 2008-12-29 2014-12-24 トレベナ・インコーポレイテッドＴｒｅｖｅｎａ， Ｉｎｃ． β−アレスチンエフェクターおよび組成物およびその使用方法
EP2809337A4 (en) * 2012-01-31 2016-05-11 Trevena Inc SS ARRESTINE EFFECTORS AND COMPOSITIONS AND METHOD FOR THE APPLICATION THEREOF
JP2017506235A (ja) 2014-02-07 2017-03-02 トレベナ・インコーポレイテッドＴｒｅｖｅｎａ， Ｉｎｃ． ベータ−アレスチンエフェクターの結晶性および非晶質形態
CA2948858A1 (en) 2014-05-19 2015-11-26 Trevena, Inc. Synthesis of beta-arrestin effectors
CN106892875B (zh) * 2016-11-11 2018-03-02 杭州唯铂莱生物科技有限公司 钙离子通道阻滞剂化合物及其制备方法和应用
TWI807411B (zh) 2017-04-27 2023-07-01 西班牙商瑪製藥股份有限公司 抗腫瘤化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2108106B (en) * 1978-07-04 1983-09-01 Shell Int Research Novel macrocyclic compounds and salts thereof useful for dissolving barium sulphate scale
SU1219587A1 (ru) * 1978-09-29 1986-03-23 Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвсср Циклические аналоги каллидина и других пахикининов,обладающие пролонгированным гипотензивным действием в сочетании с низкой или полностью отсутствующей миотропной активностью

Also Published As

Publication number Publication date
GR3007079T3 (enExample) 1993-07-30
DE68903907D1 (de) 1993-01-28
ES2054011T3 (es) 1994-08-01
EP0358418A1 (en) 1990-03-14
US5112807A (en) 1992-05-12
ATE83480T1 (de) 1993-01-15
EP0358418B1 (en) 1992-12-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee