DE69104022T2 - Antibiotisches zyklisches Hexapeptid. - Google Patents

Antibiotisches zyklisches Hexapeptid.

Info

Publication number
DE69104022T2
DE69104022T2 DE69104022T DE69104022T DE69104022T2 DE 69104022 T2 DE69104022 T2 DE 69104022T2 DE 69104022 T DE69104022 T DE 69104022T DE 69104022 T DE69104022 T DE 69104022T DE 69104022 T2 DE69104022 T2 DE 69104022T2
Authority
DE
Germany
Prior art keywords
cyclic hexapeptide
antibiotic cyclic
antibiotic
hexapeptide
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69104022T
Other languages
English (en)
Other versions
DE69104022D1 (de
Inventor
Robert E Schwartz
Thomas C Hallada
Prakash S Masurekar
Otto D Hensens
Jerrold M Liesch
David F Sesin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE69104022D1 publication Critical patent/DE69104022D1/de
Publication of DE69104022T2 publication Critical patent/DE69104022T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69104022T 1990-12-19 1991-12-11 Antibiotisches zyklisches Hexapeptid. Expired - Fee Related DE69104022T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/630,457 US5306708A (en) 1990-12-19 1990-12-19 Antibiotic agent

Publications (2)

Publication Number Publication Date
DE69104022D1 DE69104022D1 (de) 1994-10-20
DE69104022T2 true DE69104022T2 (de) 1995-04-13

Family

ID=24527241

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69104022T Expired - Fee Related DE69104022T2 (de) 1990-12-19 1991-12-11 Antibiotisches zyklisches Hexapeptid.

Country Status (7)

Country Link
US (1) US5306708A (de)
EP (1) EP0494515B1 (de)
JP (1) JP3067869B2 (de)
AT (1) ATE111487T1 (de)
CA (1) CA2057711C (de)
DE (1) DE69104022T2 (de)
IE (1) IE914418A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE910892A1 (en) * 1990-03-19 1991-09-25 Merck & Co Inc Lipopeptide compounds
IL101717A (en) * 1991-05-09 1995-12-08 Fujisawa Pharmaceutical Co Material FW34211, process for preparation, and pharmaceutical preparations that kill fungi and protozoa containing it
WO1996008266A1 (en) * 1994-09-16 1996-03-21 Merck & Co., Inc. Aza cyclohexapeptide compounds
CA2421109C (en) * 2000-08-31 2011-05-03 Hauser, Inc. Efficient method for producing compositions enriched in anthocyanins
US9394340B2 (en) 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
CN102618604B (zh) * 2011-01-31 2014-09-03 上海天伟生物制药有限公司 一种环脂肽化合物的制备方法
WO2019207413A1 (en) 2018-04-25 2019-10-31 Universidad De La República (Udelar) Cyclic hexapeptides compounds with anti-malarial activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
US5021341A (en) * 1990-03-12 1991-06-04 Merck & Co., Inc. Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol

Also Published As

Publication number Publication date
JP3067869B2 (ja) 2000-07-24
US5306708A (en) 1994-04-26
EP0494515A1 (de) 1992-07-15
ATE111487T1 (de) 1994-09-15
IE914418A1 (en) 1992-07-01
DE69104022D1 (de) 1994-10-20
EP0494515B1 (de) 1994-09-14
CA2057711C (en) 2002-01-22
JPH0692992A (ja) 1994-04-05
CA2057711A1 (en) 1992-06-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee