ATE111487T1 - Antibiotisches zyklisches hexapeptid. - Google Patents

Antibiotisches zyklisches hexapeptid.

Info

Publication number
ATE111487T1
ATE111487T1 AT91311530T AT91311530T ATE111487T1 AT E111487 T1 ATE111487 T1 AT E111487T1 AT 91311530 T AT91311530 T AT 91311530T AT 91311530 T AT91311530 T AT 91311530T AT E111487 T1 ATE111487 T1 AT E111487T1
Authority
AT
Austria
Prior art keywords
cyclic hexapeptide
antibiotic cyclic
antibiotic
hexapeptide
chem
Prior art date
Application number
AT91311530T
Other languages
English (en)
Inventor
Robert E Schwartz
Thomas C Hallada
Prakash S Masurekar
Otto D Hensens
Jerrold M Liesch
David F Sesin
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE111487T1 publication Critical patent/ATE111487T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT91311530T 1990-12-19 1991-12-11 Antibiotisches zyklisches hexapeptid. ATE111487T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/630,457 US5306708A (en) 1990-12-19 1990-12-19 Antibiotic agent

Publications (1)

Publication Number Publication Date
ATE111487T1 true ATE111487T1 (de) 1994-09-15

Family

ID=24527241

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91311530T ATE111487T1 (de) 1990-12-19 1991-12-11 Antibiotisches zyklisches hexapeptid.

Country Status (7)

Country Link
US (1) US5306708A (de)
EP (1) EP0494515B1 (de)
JP (1) JP3067869B2 (de)
AT (1) ATE111487T1 (de)
CA (1) CA2057711C (de)
DE (1) DE69104022T2 (de)
IE (1) IE914418A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE910892A1 (en) * 1990-03-19 1991-09-25 Merck & Co Inc Lipopeptide compounds
IL101717A (en) * 1991-05-09 1995-12-08 Fujisawa Pharmaceutical Co WF11234 substance a method of preparation thereof and fungicidal and protozoicidal pharmaceutical compositions containing the same
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
WO1996008266A1 (en) * 1994-09-16 1996-03-21 Merck & Co., Inc. Aza cyclohexapeptide compounds
CA2421109C (en) * 2000-08-31 2011-05-03 Hauser, Inc. Efficient method for producing compositions enriched in anthocyanins
US9394340B2 (en) 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
CN102618604B (zh) * 2011-01-31 2014-09-03 上海天伟生物制药有限公司 一种环脂肽化合物的制备方法
WO2019207413A1 (en) 2018-04-25 2019-10-31 Universidad De La República (Udelar) Cyclic hexapeptides compounds with anti-malarial activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
US5021341A (en) * 1990-03-12 1991-06-04 Merck & Co., Inc. Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol

Also Published As

Publication number Publication date
CA2057711A1 (en) 1992-06-20
JPH0692992A (ja) 1994-04-05
DE69104022T2 (de) 1995-04-13
US5306708A (en) 1994-04-26
CA2057711C (en) 2002-01-22
EP0494515B1 (de) 1994-09-14
JP3067869B2 (ja) 2000-07-24
IE914418A1 (en) 1992-07-01
DE69104022D1 (de) 1994-10-20
EP0494515A1 (de) 1992-07-15

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties