ECSP941031A - Derivados de timosina alfa 1 - Google Patents
Derivados de timosina alfa 1Info
- Publication number
- ECSP941031A ECSP941031A EC1994001031A ECSP941031A ECSP941031A EC SP941031 A ECSP941031 A EC SP941031A EC 1994001031 A EC1994001031 A EC 1994001031A EC SP941031 A ECSP941031 A EC SP941031A EC SP941031 A ECSP941031 A EC SP941031A
- Authority
- EC
- Ecuador
- Prior art keywords
- glu
- derivatives
- thr
- lys
- val
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57581—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un compuesto de la fórmula: R1-X-R2-Y (I) en donde X es Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu o un derivado o un fragmento del mismo biológicamente activo, R1 es Ac o Z en donde, Ac es un grupo acetilo y Z es (fórmula)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1308793A | 1993-02-03 | 1993-02-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP941031A true ECSP941031A (es) | 1994-09-16 |
Family
ID=21758238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC1994001031A ECSP941031A (es) | 1993-02-03 | 1994-01-28 | Derivados de timosina alfa 1 |
Country Status (7)
Country | Link |
---|---|
US (1) | US5512656A (es) |
CN (2) | CN1058500C (es) |
AU (1) | AU6235194A (es) |
EC (1) | ECSP941031A (es) |
MY (1) | MY111439A (es) |
PH (1) | PH30414A (es) |
WO (1) | WO1994018233A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5273963A (en) * | 1991-03-29 | 1993-12-28 | The George Washington University | Compositions and methods for treating small cell and nonsmall cell lung cancers |
CA2413141C (en) * | 2000-06-14 | 2014-01-07 | Chanda Zaveri | Peptides with wound healing activity |
WO2002030259A2 (en) * | 2000-10-13 | 2002-04-18 | Monash University | Disease prevention by reactivation of the thymus |
BRPI0408892A (pt) | 2003-03-28 | 2006-04-11 | Sciclone Pharmaceuticals Inc | uso de timosina alfa 1 para tratar as infecções por arpergillus |
JP2008526978A (ja) * | 2005-01-14 | 2008-07-24 | リジェナークス・バイオファーマスーティカルズ・インコーポレイテッド | 改変型βサイモシンペプチド |
ES2288118B1 (es) * | 2006-05-10 | 2008-11-01 | Bcn Peptides, S.A. | Procedimiento para sintetizar timosinas. |
US20110172155A1 (en) | 2008-03-17 | 2011-07-14 | Regenerx Biopharmaceuticals, Inc. | Beta thymosin fragments |
CN102580059A (zh) * | 2012-03-28 | 2012-07-18 | 厦门大学 | 胸腺素α原在制备预防和治疗肝癌药物中的应用 |
CN113135988B (zh) * | 2021-04-08 | 2022-04-01 | 润辉生物技术(威海)有限公司 | 一种胸腺肽β4的制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US447926A (en) * | 1891-03-10 | Process of obtaining bromine and iodine | ||
US4079127A (en) * | 1976-10-28 | 1978-03-14 | Board Of Regents Of The University Of Texas | Thymosin alpha 1 |
CH641152A5 (en) * | 1977-04-22 | 1984-02-15 | Hoffmann La Roche | Process for preparing thymosin alpha-1 and an analogue |
US4116951A (en) * | 1977-04-22 | 1978-09-26 | Hoffmann-La Roche Inc. | [Asn2 ]-thymosin α1 and analogs thereof |
US4148788A (en) * | 1978-01-23 | 1979-04-10 | Hoffmann-La Roche Inc. | Synthesis of thymosin α1 |
DE2919592A1 (de) * | 1979-05-15 | 1981-01-15 | Max Planck Gesellschaft | Verfahren zur herstellung von thymosin- alpha 1 und derivaten davon |
DE3100974A1 (de) * | 1980-01-18 | 1982-01-21 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente enthaltende arzneimittel mit immunregulierender wirkung, und thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente |
US4293455A (en) * | 1980-04-07 | 1981-10-06 | Rockefeller University | N.sup.α -Desacetylthymosinα1 and process |
EP0056594B1 (de) * | 1981-01-14 | 1984-09-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Thymosin-alpha-1-Fragmente enthaltende Arzneimittel mit immunregulierender Wirkung und Thymosin-alpha-1-Fragmente |
DE3137231A1 (de) * | 1981-09-18 | 1983-04-14 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Bis-thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-verbindungen |
US4855407A (en) * | 1985-04-11 | 1989-08-08 | Alpha-1 Biomedicals, Inc. | Solid phase process for synthesizing peptides |
-
1993
- 1993-09-27 CN CN93119346A patent/CN1058500C/zh not_active Expired - Lifetime
-
1994
- 1994-01-24 MY MYPI94000180A patent/MY111439A/en unknown
- 1994-01-28 EC EC1994001031A patent/ECSP941031A/es unknown
- 1994-02-02 WO PCT/US1994/001249 patent/WO1994018233A1/en active Application Filing
- 1994-02-02 AU AU62351/94A patent/AU6235194A/en not_active Abandoned
- 1994-02-02 PH PH47697A patent/PH30414A/en unknown
- 1994-05-20 US US08/246,572 patent/US5512656A/en not_active Expired - Lifetime
-
1998
- 1998-06-05 CN CNB98109581XA patent/CN1150208C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PH30414A (en) | 1997-05-09 |
CN1223266A (zh) | 1999-07-21 |
US5512656A (en) | 1996-04-30 |
WO1994018233A1 (en) | 1994-08-18 |
CN1150208C (zh) | 2004-05-19 |
CN1094411A (zh) | 1994-11-02 |
AU6235194A (en) | 1994-08-29 |
MY111439A (en) | 2000-05-31 |
CN1058500C (zh) | 2000-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE215962T1 (de) | Tetrapeptide derivat | |
MX9102407A (es) | 4 arilpiperazinas y 4-arilpiperidinas novedosas. | |
SE9103572D0 (sv) | Organic salts of n,n'-diacetyl cystine | |
TR199700844T1 (xx) | Pirazolil-Benzoil T�revleri. | |
TR199701654T1 (xx) | 4-Fenilaminotiyazol t�revleri. | |
ES2107284T3 (es) | Nuevas n-piridil-carboxamidas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen. | |
ATE214698T1 (de) | Neue carbamazepin hapten analoge | |
BR9714650A (pt) | " derivados farmacêuticos de ácido aminofosfÈnico " | |
AR246509A1 (es) | Una cetimina, su preparacion y un agente de entrecruzamiento que la contiene. | |
NO901760L (no) | Substituerte arylureaforbindelser som soetningsmidler med hoey styrke. | |
FI935944A0 (fi) | Pyratsolopyrimidin- samt pyrimidinylbisfosfonestrar som anti- inflammatorer | |
ECSP941031A (es) | Derivados de timosina alfa 1 | |
KR910700089A (ko) | 히드로클로로플루오로프로판의 공비 조성물 또는 공비형 조성물 | |
PT736029E (pt) | Sulfamatos de pseudofructopiranose anticonvulsivos | |
NO981393L (no) | Guanidinoproteasehemmere | |
ES2143004T3 (es) | Derivados de la milbemicina, su preparacion y uso. | |
BR9611472A (pt) | Compostos de di-terc-butilfenol contendo enxofre úteis como agentes antiinflamatórios | |
ATE90359T1 (de) | Peptide. | |
DE3685263D1 (de) | Biologisch aktive fluoreszierende zyklische nukleotide. | |
ATE31295T1 (de) | Benzoylharnstoffderivate. | |
ES2059595T3 (es) | Beta-carbonil-carboxiamidas de 1,3-tiazolidinas. | |
FI930092A0 (fi) | Indanopyrrolidinkarbamater | |
DE69104022D1 (de) | Antibiotisches zyklisches Hexapeptid. | |
ATE140460T1 (de) | Echinocandin-b-derivat | |
NO166408C (no) | Propanolderivater. |