DE68903507T2 - Antitumor-antibiotika. - Google Patents

Antitumor-antibiotika.

Info

Publication number
DE68903507T2
DE68903507T2 DE8989102599T DE68903507T DE68903507T2 DE 68903507 T2 DE68903507 T2 DE 68903507T2 DE 8989102599 T DE8989102599 T DE 8989102599T DE 68903507 T DE68903507 T DE 68903507T DE 68903507 T2 DE68903507 T2 DE 68903507T2
Authority
DE
Germany
Prior art keywords
bmy
producing
strain
streptomyces hygroscopicus
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989102599T
Other languages
German (de)
English (en)
Other versions
DE68903507D1 (de
Inventor
Murray A Kaplan
Kin Sing Lam
John Emerick Leet
James Andrew Matson
Jacqueline Mattei
Koji Tomita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DE68903507D1 publication Critical patent/DE68903507D1/de
Application granted granted Critical
Publication of DE68903507T2 publication Critical patent/DE68903507T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/55—Streptomyces hygroscopicus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE8989102599T 1988-02-16 1989-02-15 Antitumor-antibiotika. Expired - Fee Related DE68903507T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/155,778 US4994271A (en) 1988-02-16 1988-02-16 BMY-40800 antitumor antibiotics

Publications (2)

Publication Number Publication Date
DE68903507D1 DE68903507D1 (de) 1992-12-24
DE68903507T2 true DE68903507T2 (de) 1993-04-08

Family

ID=22556752

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989102599T Expired - Fee Related DE68903507T2 (de) 1988-02-16 1989-02-15 Antitumor-antibiotika.

Country Status (6)

Country Link
US (1) US4994271A (https=)
EP (1) EP0329109B1 (https=)
JP (1) JPH0216995A (https=)
AT (1) ATE82577T1 (https=)
DE (1) DE68903507T2 (https=)
GR (1) GR3006381T3 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304373A (en) * 1991-10-22 1994-04-19 Bristol-Myers Squibb Co. Antitumor antibiotic
US6964860B2 (en) * 2001-04-25 2005-11-15 Wyeth Holdings Corporation Glycopeptide antibiotics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA678011A (en) * 1964-01-14 Nakazawa Koiti Rufomycin
US3219544A (en) * 1957-03-13 1965-11-23 Bayer Ag Process for producing antibiotic
US3061514A (en) * 1959-08-26 1962-10-30 Lilly Co Eli Antibiotics a116so and a116sa and their fermentative production
FR1483731A (fr) * 1965-08-30 1967-06-09 Nouvel antibiotique et sa préparation à partir du streptomyce à usages agricoles ou industriels
US4360458A (en) * 1979-04-02 1982-11-23 Bristol-Myers Company Antitumor antibacterial agents

Also Published As

Publication number Publication date
GR3006381T3 (https=) 1993-06-21
DE68903507D1 (de) 1992-12-24
US4994271A (en) 1991-02-19
JPH0216995A (ja) 1990-01-19
EP0329109B1 (en) 1992-11-19
EP0329109A1 (en) 1989-08-23
ATE82577T1 (de) 1992-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee