DE60332538D1 - Oligosaccharid-biomarker für mucopolysaccharidosen und andere verwandte störungen - Google Patents
Oligosaccharid-biomarker für mucopolysaccharidosen und andere verwandte störungenInfo
- Publication number
- DE60332538D1 DE60332538D1 DE60332538T DE60332538T DE60332538D1 DE 60332538 D1 DE60332538 D1 DE 60332538D1 DE 60332538 T DE60332538 T DE 60332538T DE 60332538 T DE60332538 T DE 60332538T DE 60332538 D1 DE60332538 D1 DE 60332538D1
- Authority
- DE
- Germany
- Prior art keywords
- mps
- oligosaccharide
- target
- solution
- mucopolysaccharidoses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 5
- 229920001542 oligosaccharide Polymers 0.000 title abstract 5
- 150000002482 oligosaccharides Chemical class 0.000 title abstract 5
- 239000000090 biomarker Substances 0.000 title abstract 4
- 208000002678 Mucopolysaccharidoses Diseases 0.000 title abstract 2
- 208000035475 disorder Diseases 0.000 title abstract 2
- 206010028093 mucopolysaccharidosis Diseases 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 239000000243 solution Substances 0.000 abstract 3
- 238000002414 normal-phase solid-phase extraction Methods 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000013060 biological fluid Substances 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 239000012483 derivatization solution Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Cosmetics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPS2930A AUPS293002A0 (en) | 2002-06-14 | 2002-06-14 | Identification of oligosaccharides and their use in the diagnosis and evaluation of mucopolysaccharidoses and other related disorders |
| PCT/AU2003/000731 WO2003106997A1 (en) | 2002-06-14 | 2003-06-13 | Oligosaccharide biomarkers for mucopolysaccharidoses and other related disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60332538D1 true DE60332538D1 (de) | 2010-06-24 |
Family
ID=3836492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60332538T Expired - Lifetime DE60332538D1 (de) | 2002-06-14 | 2003-06-13 | Oligosaccharid-biomarker für mucopolysaccharidosen und andere verwandte störungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060286034A1 (de) |
| EP (2) | EP1532438B1 (de) |
| JP (1) | JP2005530157A (de) |
| AT (1) | ATE467834T1 (de) |
| AU (2) | AUPS293002A0 (de) |
| CA (1) | CA2488811A1 (de) |
| DE (1) | DE60332538D1 (de) |
| NO (1) | NO20050186L (de) |
| NZ (1) | NZ537512A (de) |
| TW (1) | TW200400351A (de) |
| WO (1) | WO2003106997A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4498918B2 (ja) | 2002-04-30 | 2010-07-07 | 生化学工業株式会社 | リソソーム病の検出方法 |
| US8173443B2 (en) | 2003-03-31 | 2012-05-08 | Women's And Children's Hospital | Multiplex screening for lysosomal storage disorders (LSDs) |
| JPWO2005050191A1 (ja) * | 2003-10-27 | 2007-11-29 | 宏 葛西 | 酸化的損傷グアニン化合物とこれの濃度補正物質の同時分析方法及びこの分析方法に用いる分析装置 |
| JP2006047239A (ja) * | 2004-08-09 | 2006-02-16 | National Institute Of Advanced Industrial & Technology | 硫酸化単糖の同定方法及び硫酸化単糖異性体混合物の分析方法 |
| JP4965999B2 (ja) * | 2005-12-27 | 2012-07-04 | セント ルイス ユニバーシティ | ムコ多糖症の診断方法 |
| WO2009091994A2 (en) | 2008-01-18 | 2009-07-23 | Biomarin Pharmaceutical Inc. | Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof |
| JP2009229426A (ja) * | 2008-03-25 | 2009-10-08 | Sumitomo Bakelite Co Ltd | 糖鎖分析法 |
| CA2726111C (en) * | 2008-07-23 | 2015-01-27 | P Devices Inc. | Portable plasma based diagnostic apparatus and diagnostic method |
| US8592140B2 (en) | 2009-01-02 | 2013-11-26 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
| US9029530B2 (en) | 2009-01-02 | 2015-05-12 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
| US8232073B2 (en) | 2009-01-02 | 2012-07-31 | Zacharon Pharmaceuticals, Inc. | Quantification of non-reducing end glycan residual compounds |
| US8809009B2 (en) | 2009-01-02 | 2014-08-19 | Biomarin Pharmaceutical Inc. | Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker |
| EP2776553B1 (de) * | 2011-11-07 | 2018-07-11 | Shire Human Genetic Therapies, Inc. | Biomarker für das sanfilippo-syndrom und anwendungen davon |
| US9982288B2 (en) * | 2014-04-30 | 2018-05-29 | The Nemours Foundation | Mucopolysaccharidosis IVA/VII screening and treatment method |
| MA40954A (fr) * | 2014-11-14 | 2017-09-19 | Shire Human Genetic Therapies | Détermination de niveaux de glycosaminoglycane par spectrométrie de masse |
| CN107941963A (zh) * | 2017-12-29 | 2018-04-20 | 珍奥集团股份有限公司 | 一种增加骨密度保健食品中盐酸氨基葡萄糖与硫酸软骨素的含量测定方法 |
| CN116124971A (zh) * | 2018-08-07 | 2023-05-16 | 江苏双林海洋生物药业有限公司 | 农产品中氨基葡萄糖含量的检测方法 |
| CN108872441B (zh) * | 2018-08-14 | 2021-09-03 | 江苏康缘药业股份有限公司 | 一种测定氨基葡萄糖和硫酸软骨素的方法 |
| CN109781997A (zh) * | 2019-01-22 | 2019-05-21 | 中国人民解放军总医院 | 用于诊断粘多糖病ⅱ型的生物标志物及其应用 |
| CN114264741B (zh) * | 2021-12-15 | 2022-08-19 | 山东大学 | 一种鉴别猪来源肝素是否掺反刍类动物肝素的方法 |
| IT202200007808A1 (it) | 2022-04-20 | 2023-10-20 | Luigi Michele Pavone | Composizioni terapeutiche per malattie causate da accumulo di eparan solfato |
| CN115032377B (zh) * | 2022-08-11 | 2022-11-01 | 裕菁科技(上海)有限公司 | 一种粘多糖贮积症生物标记物及应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310646A (en) * | 1988-05-13 | 1994-05-10 | Regents Of The University Of Minnesota | Method for the detection of mucopolysaccharide storage diseases |
| US5310464A (en) | 1991-01-04 | 1994-05-10 | Redepenning Jody G | Electrocrystallization of strongly adherent brushite coatings on prosthetic alloys |
| US6506384B1 (en) * | 1997-12-31 | 2003-01-14 | New York University | Early detection of mycobacterial disease |
| NZ337946A (en) * | 1998-09-25 | 2001-11-30 | Tokyo Gas Co Ltd | C-13 labelled oligosaccharides and polysaccharides useful as diagnostic agents for pancreatic exocrine function |
| RU2196988C2 (ru) * | 2000-04-19 | 2003-01-20 | Государственный новосибирский областной клинический диагностический центр | Способ диагностики мукополисахаридозов |
| MXPA02012032A (es) * | 2000-06-07 | 2003-04-25 | Univ Duke | Metodos de diagnostico de la enfermedad de pompe y otras enfermedades por almacenamiento de glucogeno. |
| GB0128498D0 (en) * | 2001-11-28 | 2002-01-23 | Inst Of Child Health | International standards for sphingolipids |
-
2002
- 2002-06-14 AU AUPS2930A patent/AUPS293002A0/en not_active Abandoned
-
2003
- 2003-06-13 WO PCT/AU2003/000731 patent/WO2003106997A1/en active Application Filing
- 2003-06-13 US US10/517,899 patent/US20060286034A1/en not_active Abandoned
- 2003-06-13 EP EP03727020A patent/EP1532438B1/de not_active Expired - Lifetime
- 2003-06-13 JP JP2004513765A patent/JP2005530157A/ja active Pending
- 2003-06-13 CA CA002488811A patent/CA2488811A1/en not_active Abandoned
- 2003-06-13 TW TW092116202A patent/TW200400351A/zh unknown
- 2003-06-13 NZ NZ537512A patent/NZ537512A/en not_active IP Right Cessation
- 2003-06-13 AT AT03727020T patent/ATE467834T1/de not_active IP Right Cessation
- 2003-06-13 DE DE60332538T patent/DE60332538D1/de not_active Expired - Lifetime
- 2003-06-13 EP EP09156934A patent/EP2081023A3/de not_active Ceased
- 2003-06-13 AU AU2003233255A patent/AU2003233255C1/en not_active Ceased
-
2005
- 2005-01-13 NO NO20050186A patent/NO20050186L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1532438A1 (de) | 2005-05-25 |
| ATE467834T1 (de) | 2010-05-15 |
| EP1532438A4 (de) | 2006-12-06 |
| JP2005530157A (ja) | 2005-10-06 |
| NO20050186L (no) | 2005-03-10 |
| EP1532438B1 (de) | 2010-05-12 |
| AU2003233255C1 (en) | 2009-07-16 |
| CA2488811A1 (en) | 2003-12-24 |
| AUPS293002A0 (en) | 2002-07-04 |
| WO2003106997A1 (en) | 2003-12-24 |
| AU2003233255A1 (en) | 2003-12-31 |
| EP2081023A2 (de) | 2009-07-22 |
| EP2081023A3 (de) | 2009-10-07 |
| NZ537512A (en) | 2006-09-29 |
| AU2003233255B2 (en) | 2009-02-19 |
| NO20050186D0 (no) | 2005-01-13 |
| US20060286034A1 (en) | 2006-12-21 |
| TW200400351A (en) | 2004-01-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20050186L (no) | Oligosakkaridbiomarkorer for mucopolysakkaridoser og andre beslektede forstyrrelser | |
| JP6947721B2 (ja) | 非アルコール性脂肪性肝炎を診断及び評価するための方法 | |
| Banne et al. | Reduced level of serum thiols in patients with a diagnosis of active disease | |
| US20090011452A1 (en) | Method of Prognosis of Mental Diseases, E.G. Autism and Cerebral Palsy | |
| HK1208467A1 (en) | Methods for the diagnosis of dementia and other neurological disorders | |
| DE69905310D1 (de) | Reflexalgorithmus zur frühen und kostengünstigen Diagnose von myokardischen Infarkten geeignet für automatisierte diagnostische Plattformen | |
| KR20150052311A (ko) | Ｆｔ-ｉｃｒ-ｍｓ/ｍｓ를 이용한 치은염 및 치주염의 바이오마커에 대한 타액 프로테옴의 분석 | |
| RU2008103988A (ru) | Способ диагностики рассеяного склероза | |
| WO2004046729A3 (en) | Bodily fluid markers of tissue hypoxia | |
| Strohmaier et al. | Spot urine samples for the metabolic evaluation of urolithiasis patients | |
| ATE242484T1 (de) | Verfahren zur untersuchung von nierenkrankheiten | |
| DE60232595D1 (de) | Methode zur diagnose von nierenerkrankungen | |
| ATE314648T1 (de) | Diagnostisches verfahren für asthma | |
| JP2009537797A (ja) | 神経変性疾患の診断及び早期診断のためのｉｎｖｉｔｒｏ方法 | |
| JP2020064055A (ja) | 脂肪性肝疾患の検出又はリスクの予測方法、脂肪性肝疾患を検出するための診断薬キット及びバイオマーカー、対象の肝線維化の進行度の判定方法、並びに対象の肝線維化の進行度を判定するためのバイオマーカー | |
| Tharwat | The cardiac biomarker troponin I and other haematological and biochemical variables in downer camels (Camelus dromedarius) | |
| JP2020034538A (ja) | 脂肪性肝疾患の検出又はリスクの予測方法、脂肪性肝疾患を検出するための診断薬キット及びバイオマーカー、対象の肝線維化の進行度の判定方法、並びに対象の肝線維化の進行度を判定するためのバイオマーカー | |
| WO2010005077A1 (ja) | パーキンソン病の疾患関連たんぱく質およびその使用 | |
| JP6592627B1 (ja) | Ｎａｆｌｄ又はｎａｓｈの検出又はリスクの予測方法、ｎａｆｌｄ又はｎａｓｈを検出するための診断薬キット、対象における肝線維化の進行度の判定方法、及び対象における肝線維化の進行度を判定するための診断薬キット | |
| DE102008022609B4 (de) | Verfahren zum Nachweis des Vorkommens von Nierensteinen und/oder Entzündungen der ableitenden Harnwege | |
| ATE237276T1 (de) | Automatisches diagnosesystem zur durchführung von immunoassays und klinisch-chemischen assays nach einem reflexalgorithmus | |
| ATE352037T1 (de) | Immunochromatographiesystem und verfahren zur gleichzeitigen identifikation von aga-und t-tg- antikörpern und verwendung dafür zur diagnose der zöliakiekrankheit | |
| Ho et al. | Percutaneous bone biopsy in the diagnosis of renal osteodystrophy | |
| BR0209681A (pt) | Método e kit para o diagnóstico in vivo ou para o monitoramento de uma doença que envolve uma reação inflamatória dentro de um paciente | |
| JP6592637B1 (ja) | Ｎａｆｌｄ又はｎａｓｈの検出又はリスクの予測方法、ｎａｆｌｄ又はｎａｓｈを検出するための診断薬キット、対象における肝線維化の進行度の判定方法、及び対象における肝線維化の進行度を判定するための診断薬キット |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |