DE60317822D1 - Stabilisierte feste polypeptidpartikel - Google Patents
Stabilisierte feste polypeptidpartikelInfo
- Publication number
- DE60317822D1 DE60317822D1 DE60317822T DE60317822T DE60317822D1 DE 60317822 D1 DE60317822 D1 DE 60317822D1 DE 60317822 T DE60317822 T DE 60317822T DE 60317822 T DE60317822 T DE 60317822T DE 60317822 D1 DE60317822 D1 DE 60317822D1
- Authority
- DE
- Germany
- Prior art keywords
- stabilized solid
- polypeptide particles
- solid polypeptide
- particles
- stabilized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 239000007787 solid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42228902P | 2002-10-29 | 2002-10-29 | |
| PCT/US2003/034229 WO2004039392A2 (en) | 2002-10-29 | 2003-10-28 | Stabilized, solid-state polypeptide particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60317822D1 true DE60317822D1 (de) | 2008-01-10 |
Family
ID=32230336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60317822T Expired - Lifetime DE60317822D1 (de) | 2002-10-29 | 2003-10-28 | Stabilisierte feste polypeptidpartikel |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20060198894A1 (de) |
| EP (1) | EP1562626B1 (de) |
| JP (1) | JP2006504772A (de) |
| KR (1) | KR20050083841A (de) |
| CN (1) | CN1708314A (de) |
| AU (1) | AU2003285075B2 (de) |
| BR (1) | BR0315782A (de) |
| CA (1) | CA2502378A1 (de) |
| DE (1) | DE60317822D1 (de) |
| EC (1) | ECSP055822A (de) |
| IL (1) | IL168106A0 (de) |
| MX (1) | MXPA05004593A (de) |
| MY (1) | MY138608A (de) |
| NO (1) | NO20052422L (de) |
| NZ (2) | NZ562480A (de) |
| PL (1) | PL376219A1 (de) |
| RU (1) | RU2329823C2 (de) |
| TW (1) | TW200505497A (de) |
| WO (1) | WO2004039392A2 (de) |
| ZA (1) | ZA200504311B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2107069T3 (pl) | 2003-08-05 | 2013-06-28 | Novo Nordisk As | Nowe pochodne insuliny |
| US20190330295A1 (en) * | 2005-05-04 | 2019-10-31 | Zealand Pharma A/S | Glucagon-like-peptide-2 (glp-2) analogues |
| ES2371361T3 (es) | 2005-12-28 | 2011-12-30 | Novo Nordisk A/S | Composiciones que comprenden una insulina acilada y zinc y método de producción de dichas composiciones. |
| JP4847775B2 (ja) * | 2006-03-29 | 2011-12-28 | シーシーアイ株式会社 | 安定なポリオール脱水素酵素組成物 |
| WO2008152106A1 (en) | 2007-06-13 | 2008-12-18 | Novo Nordisk A/S | Pharmaceutical formulation comprising an insulin derivative |
| MX2011004357A (es) | 2008-10-30 | 2011-05-23 | Novo Nordisk As | Tratamiento de diabetes mellitus utilizando inyecciones de insulina con una frecuencia de inyeccion menor que a diario. |
| SI2603232T1 (sl) | 2010-08-11 | 2020-03-31 | Ironwood Pharmaceuticals, Inc. | Stabilne formulacije linaklotida |
| DK2632478T3 (da) | 2010-10-27 | 2019-10-07 | Novo Nordisk As | Behandling af diabetes melitus under anvendelse af insulinindsprøjtninger indgivet med varierende indsprøjtningsintervaller |
| JP2016519127A (ja) | 2013-04-30 | 2016-06-30 | ノヴォ ノルディスク アー／エス | 新規投与レジメン |
| US10335464B1 (en) | 2018-06-26 | 2019-07-02 | Novo Nordisk A/S | Device for titrating basal insulin |
| WO2024209050A1 (en) | 2023-04-05 | 2024-10-10 | Antag Therapeutics Aps | Gip activity modulators and orthostatic intolerance |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816440A (en) * | 1985-09-26 | 1989-03-28 | Cetus Corporation | Stable formulation of biologically active proteins for parenteral injection |
| US4806343A (en) * | 1986-03-13 | 1989-02-21 | University Of Southwestern Louisiana | Cryogenic protectant for proteins |
| JPH02218618A (ja) * | 1989-02-21 | 1990-08-31 | Green Cross Corp:The | トロンビン粉末製剤 |
| US5128242A (en) * | 1989-06-19 | 1992-07-07 | The Administrators Of The Tulane Educational Fund | Hypothalamic polypeptides with adenylate cyclase stimulating activity |
| DE69210645T2 (de) * | 1991-02-19 | 1996-11-28 | Takeda Chemical Industries, Ltd., Osaka | Verfahren zur Herstellung von cysteinfreien Peptiden |
| JP3356816B2 (ja) * | 1992-03-24 | 2002-12-16 | セイコーインスツルメンツ株式会社 | 半導体光電気変換装置 |
| JPH083056A (ja) * | 1994-06-17 | 1996-01-09 | Nippon Kayaku Co Ltd | 末梢神経障害の軽減剤 |
| JPH08131171A (ja) * | 1994-11-11 | 1996-05-28 | Asahi Chem Ind Co Ltd | 逆転写酵素の安定化組成物 |
| US6267958B1 (en) * | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| US6156331A (en) * | 1996-02-02 | 2000-12-05 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
| US6395292B2 (en) * | 1996-02-02 | 2002-05-28 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
| NZ331186A (en) * | 1996-02-02 | 2000-04-28 | Alza Corp | Osmotically driven sustained delivery drug delivery capsule |
| US5763401A (en) * | 1996-07-12 | 1998-06-09 | Bayer Corporation | Stabilized albumin-free recombinant factor VIII preparation having a low sugar content |
| ES2158611T3 (es) * | 1996-12-20 | 2001-09-01 | Alza Corp | Composicion en gel inyectable con efecto retard y procedimiento para la preparacion de dicha composicion. |
| EA002149B1 (ru) * | 1997-04-28 | 2001-12-24 | Эли Лилли Энд Компани | Улучшенные способы приготовления активированного белка с |
| JP4156688B2 (ja) * | 1997-07-22 | 2008-09-24 | アルフレッサファーマ株式会社 | 安定なヘモグロビン含有組成物 |
| WO1999032095A1 (en) * | 1997-12-22 | 1999-07-01 | Alza Corporation | Rate controlling membranes for controlled drug delivery devices |
| PT1041974E (pt) * | 1997-12-30 | 2007-01-31 | Alza Corp | Sistema de entrega de agente benéfico como obturador de membrana |
| DE60034445T2 (de) * | 1999-05-31 | 2008-01-03 | Mitsubishi Chemical Corp. | Gefriergetrocknete hgf-präparationen |
| JP2006514914A (ja) * | 2002-02-14 | 2006-05-18 | バイエル・フアーマシユーチカルズ・コーポレーシヨン | 有機溶媒中および乾燥状態のペプチドの安定化における製剤の戦略 |
| GB0207092D0 (en) * | 2002-03-26 | 2002-05-08 | Sod Conseils Rech Applic | Stable pharmaceutical composition containing factor VIII |
-
2003
- 2003-10-28 KR KR1020057007327A patent/KR20050083841A/ko not_active Application Discontinuation
- 2003-10-28 AU AU2003285075A patent/AU2003285075B2/en not_active Ceased
- 2003-10-28 DE DE60317822T patent/DE60317822D1/de not_active Expired - Lifetime
- 2003-10-28 PL PL03376219A patent/PL376219A1/xx not_active Application Discontinuation
- 2003-10-28 EP EP03779390A patent/EP1562626B1/de not_active Expired - Lifetime
- 2003-10-28 NZ NZ562480A patent/NZ562480A/en not_active IP Right Cessation
- 2003-10-28 BR BR0315782-2A patent/BR0315782A/pt not_active IP Right Cessation
- 2003-10-28 CA CA002502378A patent/CA2502378A1/en not_active Abandoned
- 2003-10-28 US US10/696,405 patent/US20060198894A1/en not_active Abandoned
- 2003-10-28 MX MXPA05004593A patent/MXPA05004593A/es active IP Right Grant
- 2003-10-28 RU RU2005116250/15A patent/RU2329823C2/ru not_active IP Right Cessation
- 2003-10-28 WO PCT/US2003/034229 patent/WO2004039392A2/en active IP Right Grant
- 2003-10-28 JP JP2004548544A patent/JP2006504772A/ja active Pending
- 2003-10-28 CN CNA2003801023848A patent/CN1708314A/zh active Pending
- 2003-10-28 NZ NZ539811A patent/NZ539811A/en unknown
- 2003-10-29 TW TW092129977A patent/TW200505497A/zh unknown
- 2003-10-29 MY MYPI20034115A patent/MY138608A/en unknown
-
2005
- 2005-04-18 IL IL168106A patent/IL168106A0/en unknown
- 2005-05-19 NO NO20052422A patent/NO20052422L/no not_active Application Discontinuation
- 2005-05-26 ZA ZA200504311A patent/ZA200504311B/en unknown
- 2005-05-30 EC EC2005005822A patent/ECSP055822A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003285075B2 (en) | 2009-10-29 |
| NZ539811A (en) | 2008-08-29 |
| RU2005116250A (ru) | 2006-01-20 |
| MXPA05004593A (es) | 2005-07-26 |
| ZA200504311B (en) | 2006-07-26 |
| AU2003285075A1 (en) | 2004-05-25 |
| IL168106A0 (en) | 2009-02-11 |
| TW200505497A (en) | 2005-02-16 |
| EP1562626B1 (de) | 2007-11-28 |
| EP1562626A2 (de) | 2005-08-17 |
| MY138608A (en) | 2009-07-31 |
| WO2004039392A2 (en) | 2004-05-13 |
| NO20052422L (no) | 2005-07-20 |
| CN1708314A (zh) | 2005-12-14 |
| RU2329823C2 (ru) | 2008-07-27 |
| JP2006504772A (ja) | 2006-02-09 |
| CA2502378A1 (en) | 2004-05-13 |
| ECSP055822A (es) | 2005-08-11 |
| NO20052422D0 (no) | 2005-05-19 |
| BR0315782A (pt) | 2005-09-20 |
| US20060198894A1 (en) | 2006-09-07 |
| NZ562480A (en) | 2009-08-28 |
| PL376219A1 (en) | 2005-12-27 |
| KR20050083841A (ko) | 2005-08-26 |
| WO2004039392A3 (en) | 2004-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |