DE60310975T2 - Verwendung von epothilone zur behandlung hyperparathyreoidismus - Google Patents

Verwendung von epothilone zur behandlung hyperparathyreoidismus Download PDF

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Publication number
DE60310975T2
DE60310975T2 DE60310975T DE60310975T DE60310975T2 DE 60310975 T2 DE60310975 T2 DE 60310975T2 DE 60310975 T DE60310975 T DE 60310975T DE 60310975 T DE60310975 T DE 60310975T DE 60310975 T2 DE60310975 T2 DE 60310975T2
Authority
DE
Germany
Prior art keywords
parathyroid
treatment
epothilone
lower alkyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60310975T
Other languages
German (de)
English (en)
Other versions
DE60310975D1 (de
Inventor
A. Eugene Kenner WOLTERING
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Louisiana State University
Original Assignee
Louisiana State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Louisiana State University filed Critical Louisiana State University
Application granted granted Critical
Publication of DE60310975D1 publication Critical patent/DE60310975D1/de
Publication of DE60310975T2 publication Critical patent/DE60310975T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60310975T 2002-10-15 2003-10-13 Verwendung von epothilone zur behandlung hyperparathyreoidismus Expired - Lifetime DE60310975T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41859202P 2002-10-15 2002-10-15
US418592P 2002-10-15
PCT/IB2003/004514 WO2004035050A1 (en) 2002-10-15 2003-10-13 Use of epothilone derivatives for the treatment of hyperparathyroidism

Publications (2)

Publication Number Publication Date
DE60310975D1 DE60310975D1 (de) 2007-02-15
DE60310975T2 true DE60310975T2 (de) 2007-07-12

Family

ID=32107949

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60310975T Expired - Lifetime DE60310975T2 (de) 2002-10-15 2003-10-13 Verwendung von epothilone zur behandlung hyperparathyreoidismus

Country Status (15)

Country Link
US (2) US20060142354A1 (https=)
EP (1) EP1553938B1 (https=)
JP (1) JP4672368B2 (https=)
CN (1) CN1297269C (https=)
AT (1) ATE350034T1 (https=)
AU (1) AU2003267751A1 (https=)
BR (1) BR0315293A (https=)
CA (1) CA2501717C (https=)
CY (1) CY1106385T1 (https=)
DE (1) DE60310975T2 (https=)
DK (1) DK1553938T3 (https=)
ES (1) ES2279139T3 (https=)
PT (1) PT1553938E (https=)
SI (1) SI1553938T1 (https=)
WO (1) WO2004035050A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60330407D1 (de) 2002-08-23 2010-01-14 Sloan Kettering Inst Cancer Synthese von Epothilonen, Zwischenprodukte davon, Analoga und ihre Verwendung
US6921769B2 (en) 2002-08-23 2005-07-26 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1155689B1 (en) * 1993-07-19 2006-09-20 Angiotech Pharmaceuticals, Inc. Anti-angiogenic stents and methods of their preparation
DK1367057T3 (da) * 1996-11-18 2009-01-19 Biotechnolog Forschung Gmbh Epothiloner E og F
US6380394B1 (en) * 1996-12-13 2002-04-30 The Scripps Research Institute Epothilone analogs
SK287775B6 (sk) * 1998-02-05 2011-09-05 Novartis Ag Farmaceutická formulácia obsahujúca epothilon, infúzny roztok a použitie farmaceutickej formulácie
US6302838B1 (en) * 1998-02-25 2001-10-16 Novartis Ag Cancer treatment with epothilones

Also Published As

Publication number Publication date
US20110152329A1 (en) 2011-06-23
BR0315293A (pt) 2005-08-30
EP1553938A1 (en) 2005-07-20
DE60310975D1 (de) 2007-02-15
JP4672368B2 (ja) 2011-04-20
EP1553938B1 (en) 2007-01-03
AU2003267751A1 (en) 2004-05-04
WO2004035050A1 (en) 2004-04-29
CN1703217A (zh) 2005-11-30
DK1553938T3 (da) 2007-03-26
SI1553938T1 (sl) 2007-06-30
CY1106385T1 (el) 2011-10-12
ES2279139T3 (es) 2007-08-16
CA2501717C (en) 2012-09-18
CN1297269C (zh) 2007-01-31
JP2006504751A (ja) 2006-02-09
ATE350034T1 (de) 2007-01-15
CA2501717A1 (en) 2004-04-29
US20060142354A1 (en) 2006-06-29
PT1553938E (pt) 2007-03-30
HK1080768A1 (en) 2006-05-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN