DE60306133T2 - Verbindung eines antithrombotischen mittels mit aspirin und dessen verwendung zur behandlung von atherothrombotischen erkrankungen - Google Patents

Verbindung eines antithrombotischen mittels mit aspirin und dessen verwendung zur behandlung von atherothrombotischen erkrankungen Download PDF

Info

Publication number
DE60306133T2
DE60306133T2 DE60306133T DE60306133T DE60306133T2 DE 60306133 T2 DE60306133 T2 DE 60306133T2 DE 60306133 T DE60306133 T DE 60306133T DE 60306133 T DE60306133 T DE 60306133T DE 60306133 T2 DE60306133 T2 DE 60306133T2
Authority
DE
Germany
Prior art keywords
compound
aspirin
pharmaceutically acceptable
treatment
pharmaceutical preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60306133T
Other languages
German (de)
English (en)
Other versions
DE60306133D1 (de
Inventor
Tony Verbeuren
Gilbert Lavielle
Bernard Cimetiere
Marie-Odile Vallez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Les Laboratoires Servier SAS
Original Assignee
Les Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS
Application granted granted Critical
Publication of DE60306133D1 publication Critical patent/DE60306133D1/de
Publication of DE60306133T2 publication Critical patent/DE60306133T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60306133T 2002-04-05 2003-04-04 Verbindung eines antithrombotischen mittels mit aspirin und dessen verwendung zur behandlung von atherothrombotischen erkrankungen Expired - Fee Related DE60306133T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0204222A FR2838057B1 (fr) 2002-04-05 2002-04-05 Nouvelle association d'un antithrombotique et d'aspirine
FR0204222 2002-04-05
PCT/FR2003/001054 WO2003084525A1 (fr) 2002-04-05 2003-04-04 Nouvelle association d'un antithrombotique et d'aspirine

Publications (2)

Publication Number Publication Date
DE60306133D1 DE60306133D1 (de) 2006-07-27
DE60306133T2 true DE60306133T2 (de) 2007-01-04

Family

ID=28052120

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60306133T Expired - Fee Related DE60306133T2 (de) 2002-04-05 2003-04-04 Verbindung eines antithrombotischen mittels mit aspirin und dessen verwendung zur behandlung von atherothrombotischen erkrankungen

Country Status (26)

Country Link
US (1) US7618955B2 (https=)
EP (1) EP1496884B1 (https=)
JP (1) JP4065853B2 (https=)
KR (1) KR100645143B1 (https=)
CN (1) CN1297265C (https=)
AR (1) AR039253A1 (https=)
AT (1) ATE329591T1 (https=)
AU (1) AU2003246774B2 (https=)
BR (1) BR0309019A (https=)
CA (1) CA2480697A1 (https=)
CY (1) CY1105106T1 (https=)
DE (1) DE60306133T2 (https=)
DK (1) DK1496884T3 (https=)
EA (1) EA006978B1 (https=)
ES (1) ES2264533T3 (https=)
FR (1) FR2838057B1 (https=)
GE (1) GEP20074101B (https=)
MA (1) MA27114A1 (https=)
MX (1) MXPA04009760A (https=)
NO (1) NO20044700L (https=)
NZ (1) NZ535430A (https=)
PL (1) PL371620A1 (https=)
PT (1) PT1496884E (https=)
UA (1) UA79457C2 (https=)
WO (1) WO2003084525A1 (https=)
ZA (1) ZA200407593B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SMP200800012B (it) * 2005-07-22 2008-02-27 Procter & Gamble Composizioni per ridurre l'incidenza di aritmia indotta da farmaco
EP2155195B1 (en) * 2007-04-13 2014-07-16 Millennium Pharmaceuticals, Inc. Combination anticoagulant therapy with a compound that acts as a factor Xa inhibitor
JP2009001537A (ja) * 2007-06-25 2009-01-08 Lab Servier 血管障害の処置を目的とする医薬の入手における抗アテローム血栓化合物の使用
FR2920772B1 (fr) * 2007-09-11 2009-10-23 Servier Lab Association entre un anti-atherothrombotique et un inhibiteur de l'enzyme de conversion de l'angiotensine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2711139B1 (fr) * 1993-10-15 1995-12-01 Adir Nouveaux dérivés de 1,2,3,4-tétrahydronaphtalène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
US7618955B2 (en) 2009-11-17
FR2838057A1 (fr) 2003-10-10
FR2838057B1 (fr) 2005-07-08
ES2264533T3 (es) 2007-01-01
UA79457C2 (en) 2007-06-25
HK1076034A1 (en) 2006-01-06
AU2003246774B2 (en) 2007-02-15
PT1496884E (pt) 2006-09-29
JP4065853B2 (ja) 2008-03-26
CN1646111A (zh) 2005-07-27
NZ535430A (en) 2006-09-29
CY1105106T1 (el) 2009-11-04
NO20044700L (no) 2004-10-29
EA200401293A1 (ru) 2005-02-24
EP1496884A1 (fr) 2005-01-19
BR0309019A (pt) 2005-02-01
ZA200407593B (en) 2006-07-26
WO2003084525A1 (fr) 2003-10-16
ATE329591T1 (de) 2006-07-15
CN1297265C (zh) 2007-01-31
MA27114A1 (fr) 2004-12-20
GEP20074101B (en) 2007-05-10
DK1496884T3 (da) 2006-10-02
JP2005528376A (ja) 2005-09-22
CA2480697A1 (fr) 2003-10-16
KR20040098053A (ko) 2004-11-18
KR100645143B1 (ko) 2006-11-10
DE60306133D1 (de) 2006-07-27
MXPA04009760A (es) 2004-12-13
US20050143354A1 (en) 2005-06-30
EP1496884B1 (fr) 2006-06-14
PL371620A1 (en) 2005-06-27
AU2003246774A1 (en) 2003-10-20
EA006978B1 (ru) 2006-06-30
AR039253A1 (es) 2005-02-16

Similar Documents

Publication Publication Date Title
DE69930243T2 (de) Behandlung iatrogenen und altersbedingten bluthochdruck mit vitamin b6-derivative, und pharmazeutische zusammensetzungen verwendbar dazu
DE69635959T2 (de) Behandlung negativer und kognitiver symptome der schizophrenie mit antagonisten der glycinaufnahme
AT403122B (de) Therapeutische infusionszubereitung auf basis von aminosäurederivaten
DE69400799T2 (de) Verwendung von riluzol zur behandlung von parkinson und den parkinson-syndromen
DE69029654T2 (de) Verwendung von lipoxin a 4? und dessen derivaten als antagonisten für trägreagierende anaphylaxmittel
DE69434560T2 (de) Kombination eines Angiotensin-II antagonistisch wirkenden Benzimidazols mit Manidipin zur Behandlung von Bluthochdruck
DE60118953T2 (de) Farnesyl-protein-transferasehemmer zur behandlung der entzündlichen darmerkrankung
DE3872029T2 (de) Rektal absorbierbare form von l-dopa.
DE60218497T2 (de) Kombination eines nsaids und eines pde-4 inhibitors
DE60106026T2 (de) 2-arachidonylglycerol (2-ag)-ein hemmer des tumor nekrose faktors-alfa und neuroprotektor des gehirns bei geschlossenen kopfverletzungen
DE68904358T2 (de) Prostaglandinanaloge zur verwendung in der medizin.
DE3390114T1 (de) Verbesserte analgetische und antiinflammatorische, Ibuprofen enthaltende Zubereitungen und Verfahren zu ihrer Herstellung
DE60026491T2 (de) Melagatran zur behandlung von entzündungen
LU84892A1 (fr) Komposition zur reduktion der sebumsekretion
DE2514335C3 (de) Oral zu verabreichendes Arzneimittel mit Antiplasmin-Inhibitorwirkung
DE60306133T2 (de) Verbindung eines antithrombotischen mittels mit aspirin und dessen verwendung zur behandlung von atherothrombotischen erkrankungen
DE69226487T2 (de) Verwendung von Furanonderivaten zur Vorbeugung oder Behandlung von Autoimmunkrankheiten
DE3415394A1 (de) Medikament gegen ovarialinsuffizienz
WO2001082858A2 (de) Neue verbindungen zur behandlung inflammatorischer und kardiovaskulärer erkrankungen
DE69800804T2 (de) Halbfeste pharmazeutische zubereitungen enthaltend dexketoprofen-trometamol
DE2206570B2 (de) Verwendung von ( + ) - Catechin
DE10306179A1 (de) Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe
DE19726871C1 (de) Synergistisch wirkende Zusammensetzungen zur selektiven Bekämpfung von Tumorgewebe
DE69907387T2 (de) Verwendung von Hydantoin-Derivaten zur Herstellung eines Medikaments zur Behandlung von refraktärer Vasculitis.
EP0206297B1 (de) 4-Amino-2-(imidazolidin-2-on-l-yl)-pyrimidin-5-carbonsäure-(N-(3-trifluormethyl-phenyl)-amide) zur antithrombotischen Prophylaxe und Behandlung sowie ihre Verwendung zur Herstellung von antithrombotisch wirksamen Arzneimitteln

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee