DE60237449D1 - Ammensetzungen und damit in beziehung stehende verwendungen - Google Patents
Ammensetzungen und damit in beziehung stehende verwendungenInfo
- Publication number
- DE60237449D1 DE60237449D1 DE60237449T DE60237449T DE60237449D1 DE 60237449 D1 DE60237449 D1 DE 60237449D1 DE 60237449 T DE60237449 T DE 60237449T DE 60237449 T DE60237449 T DE 60237449T DE 60237449 D1 DE60237449 D1 DE 60237449D1
- Authority
- DE
- Germany
- Prior art keywords
- polymers
- compositions
- amments
- related uses
- nanospheres
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 abstract 3
- 229920000642 polymer Polymers 0.000 abstract 3
- 229920002988 biodegradable polymer Polymers 0.000 abstract 1
- 239000004621 biodegradable polymer Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000004005 microsphere Substances 0.000 abstract 1
- 239000002077 nanosphere Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyethers (AREA)
- Biological Depolymerization Polymers (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29972901P | 2001-06-22 | 2001-06-22 | |
| PCT/US2002/019772 WO2003000237A2 (en) | 2001-06-22 | 2002-06-21 | Biodegradable polymer coompositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60237449D1 true DE60237449D1 (de) | 2010-10-07 |
Family
ID=23156038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60237449T Expired - Lifetime DE60237449D1 (de) | 2001-06-22 | 2002-06-21 | Ammensetzungen und damit in beziehung stehende verwendungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7163697B2 (enExample) |
| EP (1) | EP1406593B1 (enExample) |
| JP (1) | JP4758607B2 (enExample) |
| AT (1) | ATE478656T1 (enExample) |
| AU (1) | AU2002322289A1 (enExample) |
| DE (1) | DE60237449D1 (enExample) |
| WO (1) | WO2003000237A2 (enExample) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2466039A1 (en) * | 2001-11-23 | 2003-06-05 | Rutgers, The State University | Improved synthesis of polyanhydrides |
| US7351749B2 (en) * | 2002-12-16 | 2008-04-01 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Process for manufacture of personal care products utilizing a concentrate water phase |
| US7662864B2 (en) * | 2003-06-04 | 2010-02-16 | Rutgers, The State University Of New Jersey | Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent |
| EP1686963A1 (en) * | 2003-10-27 | 2006-08-09 | PSivida Inc. | Suspension delivery system for the sustained and controlled local release of pharmaceuticals |
| JP2005206491A (ja) * | 2004-01-21 | 2005-08-04 | Medgel Corp | 肺気腫を治療するための経肺投与用製剤 |
| EP1713514B1 (en) * | 2004-01-28 | 2021-11-24 | Johns Hopkins University | Drugs and gene carrier particles that rapidly move through mucous barriers |
| CA2590098C (en) * | 2004-12-10 | 2015-03-31 | Justin Hanes | Functionalized poly (ether-anhydride) block copolymers |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| FR2887886B1 (fr) † | 2005-07-01 | 2010-01-08 | Oreal | Polymere cationique neutralise, composition le comprenant et procede de traitement cosmetique |
| US20070225472A1 (en) * | 2006-03-23 | 2007-09-27 | Varshney Sunil K | Polyanhydride polymers and their uses in biomedical devices |
| CA2648291A1 (en) * | 2006-04-04 | 2007-11-01 | Stc.Unm | Swellable particles for drug delivery |
| US20080014170A1 (en) * | 2006-07-14 | 2008-01-17 | Olexander Hnojewyj | Drug delivery polyanhydride composition and method |
| ITMI20061539A1 (it) * | 2006-08-02 | 2008-02-03 | Mediolanum Pharmaceuticals Ltd | Impianti sottocutanei in grado di rilasciare il principio attivo per un periodo prolungato di tempo |
| AU2007284759B2 (en) | 2006-08-09 | 2010-10-28 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
| DE602007012559D1 (de) * | 2006-09-08 | 2011-03-31 | Univ Johns Hopkins | H die schleimhaut |
| US20090169628A1 (en) | 2006-10-17 | 2009-07-02 | Armark Authentication Technologies, Llc | Article and method for focused delivery of therapeutic and/or diagnostic materials |
| NO20065147L (no) * | 2006-11-08 | 2008-05-09 | Ntnu Tech Transfer As | Nanokompositter basert på cellulosewhiskers og celluloseplast |
| JP5578655B2 (ja) | 2007-03-02 | 2014-08-27 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ | 微粒子による薬物送達 |
| US8623397B2 (en) * | 2007-04-13 | 2014-01-07 | The Regents Of The University Of Michigan | Delivery device and method for forming the same |
| RU2440097C2 (ru) | 2007-04-23 | 2012-01-20 | Интарсия Терапьютикс, Инк. | Способ лечения диабета ii типа и ожирения, осмотическое устройство для доставки и способ его изготовления |
| US20080311172A1 (en) * | 2007-04-25 | 2008-12-18 | Schapira Jay N | Programmed-release, nanostructured biological construct |
| CA2708514A1 (en) * | 2007-12-31 | 2009-07-16 | Armark Authentication Technologies, Llc | Article and method for focused delivery of therapeutic and/or diagnostic materials |
| US8343140B2 (en) | 2008-02-13 | 2013-01-01 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
| EP2315571A4 (en) * | 2008-07-16 | 2013-05-01 | Surmodics Pharmaceuticals Inc | METHOD FOR PRODUCING MICROPARTICLES WITH BIOACTIVE PEPTIDES |
| SMT202000405T1 (it) * | 2008-09-04 | 2020-09-10 | Amylin Pharmaceuticals Llc | Formulazioni a rilascio prolungato usando veicolanti non acquosi |
| US8822610B2 (en) * | 2008-12-22 | 2014-09-02 | ATRP Solutions, Inc. | Control over controlled radical polymerization processes |
| US8815971B2 (en) | 2008-12-22 | 2014-08-26 | ATRP Solutions, Inc. | Control over controlled radical polymerization processes |
| US9783628B2 (en) | 2009-04-23 | 2017-10-10 | ATRP Solutions, Inc. | Dual-mechanism thickening agents for hydraulic fracturing fluids |
| US8173750B2 (en) * | 2009-04-23 | 2012-05-08 | ATRP Solutions, Inc. | Star macromolecules for personal and home care |
| WO2010123574A1 (en) | 2009-04-23 | 2010-10-28 | Atrp Solutions Inc | Star macromolecules for personal and home care |
| WO2011037623A1 (en) | 2009-09-28 | 2011-03-31 | Intarcia Therapeutics, Inc. | Rapid establishment and/or termination of substantial steady-state drug delivery |
| WO2011084458A2 (en) * | 2009-12-15 | 2011-07-14 | The Johns Hopkins University | Polymer-based compositions and methods for treatment of peritoneal disorders |
| US9587064B2 (en) | 2010-12-08 | 2017-03-07 | ATRP Solutions, Inc. | Salt-tolerant star macromolecules |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| US9056057B2 (en) | 2012-05-03 | 2015-06-16 | Kala Pharmaceuticals, Inc. | Nanocrystals, compositions, and methods that aid particle transport in mucus |
| US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| EP2844227B1 (en) | 2012-05-03 | 2020-11-18 | Kala Pharmaceuticals, Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| JP6294885B2 (ja) | 2012-08-30 | 2018-03-14 | エーティーアールピー ソリューションズ インコーポレイテッドATRP Solutions,Inc. | 星形高分子、星形高分子組成物および星形高分子の製造方法 |
| EP2951220B1 (en) | 2013-02-04 | 2020-11-25 | Pilot Polymer Technologies, Inc. | Salt-tolerant star macromolecules |
| EP2956138B1 (en) | 2013-02-15 | 2022-06-22 | Kala Pharmaceuticals, Inc. | Therapeutic compounds and uses thereof |
| US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
| ES2831625T3 (es) | 2013-02-20 | 2021-06-09 | Kala Pharmaceuticals Inc | Compuestos terapéuticos y sus usos |
| CN108530458A (zh) | 2013-11-01 | 2018-09-14 | 卡拉制药公司 | 治疗化合物的结晶形式及其用途 |
| US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| WO2015168143A1 (en) * | 2014-04-28 | 2015-11-05 | The Johns Hopkins University | Biopolymer-encapsulated glycosyltransferase inhibitor compositions and methods for treating diabetes and cardiac indications |
| US10023521B2 (en) | 2014-06-13 | 2018-07-17 | Rutgers, The State University Of New Jersey | Process and intermediates for preparing poly(anhydride-esters) |
| EP3164429A4 (en) | 2014-07-03 | 2017-12-20 | ATRP Solutions, Inc. | Surfactant-compatible star macromolecules |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| ES2968262T3 (es) | 2015-06-03 | 2024-05-08 | I2O Therapeutics Inc | Sistemas de colocación de implantes |
| BR112018009644A2 (pt) | 2015-11-12 | 2018-11-06 | Graybug Vision Inc | micropartículas agregantes sólidas modificadas na superfície, material injetável, processo para preparação de micropartículas agregantes sólidas modificadas na superfície, método para tratamento de um distúrbio ocular, e, uso de micropartículas agregantes sólidas modificadas na superfície |
| CA3024479A1 (en) | 2016-05-16 | 2017-11-23 | Intarcia Therapeutics, Inc. | Glucagon-receptor selective polypeptides and methods of use thereof |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| US10253036B2 (en) | 2016-09-08 | 2019-04-09 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| EP3509421A4 (en) | 2016-09-08 | 2020-05-20 | Kala Pharmaceuticals, Inc. | CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF |
| EP3509423A4 (en) | 2016-09-08 | 2020-05-13 | Kala Pharmaceuticals, Inc. | CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF |
| JP7286542B2 (ja) | 2017-01-03 | 2023-06-05 | インターシア セラピューティクス,インコーポレイティド | Glp-1受容体アゴニストの持続的投与及び薬物の同時投与を含む方法 |
| WO2018175922A1 (en) | 2017-03-23 | 2018-09-27 | Graybug Vision, Inc. | Drugs and compositions for the treatment of ocular disorders |
| CN111201040A (zh) | 2017-05-10 | 2020-05-26 | 灰色视觉公司 | 用于医学疗法的缓释微粒及其悬浮液 |
| WO2020232005A1 (en) * | 2019-05-13 | 2020-11-19 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Polymer-based implant for retinal therapy and methods of making and using the same |
| CN112495319B (zh) * | 2020-09-29 | 2023-07-04 | 海丰生物科技(北京)有限公司 | 一种环瓜氨酸肽双微球偶联物及其制备方法与应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4757128A (en) * | 1986-08-01 | 1988-07-12 | Massachusetts Institute Of Technology | High molecular weight polyanhydride and preparation thereof |
| CH671402A5 (enExample) * | 1985-10-02 | 1989-08-31 | Sandoz Ag | |
| US4789724A (en) * | 1986-10-17 | 1988-12-06 | Massachusetts Institute Of Technology | Preparation of anhydride copolymers |
| US5718921A (en) * | 1987-03-13 | 1998-02-17 | Massachusetts Institute Of Technology | Microspheres comprising polymer and drug dispersed there within |
| WO1995003356A1 (en) * | 1993-07-23 | 1995-02-02 | Massachusetts Institute Of Technology | Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers |
| US5565215A (en) * | 1993-07-23 | 1996-10-15 | Massachusettes Institute Of Technology | Biodegradable injectable particles for imaging |
| AU1702395A (en) * | 1994-02-17 | 1995-09-04 | Pankaj Modi | Drugs, vaccines and hormones in polylactide coated microspheres |
| US5985309A (en) * | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
| JP2000143538A (ja) * | 1998-11-04 | 2000-05-23 | Teijin Ltd | 免疫調節剤を含有する医薬組成物 |
-
2002
- 2002-06-21 JP JP2003506884A patent/JP4758607B2/ja not_active Expired - Lifetime
- 2002-06-21 WO PCT/US2002/019772 patent/WO2003000237A2/en not_active Ceased
- 2002-06-21 US US10/177,748 patent/US7163697B2/en not_active Expired - Lifetime
- 2002-06-21 DE DE60237449T patent/DE60237449D1/de not_active Expired - Lifetime
- 2002-06-21 EP EP02756268A patent/EP1406593B1/en not_active Expired - Lifetime
- 2002-06-21 AT AT02756268T patent/ATE478656T1/de not_active IP Right Cessation
- 2002-06-21 AU AU2002322289A patent/AU2002322289A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004538347A (ja) | 2004-12-24 |
| ATE478656T1 (de) | 2010-09-15 |
| AU2002322289A1 (en) | 2003-01-08 |
| EP1406593B1 (en) | 2010-08-25 |
| US20030086895A1 (en) | 2003-05-08 |
| WO2003000237A3 (en) | 2003-03-27 |
| WO2003000237A2 (en) | 2003-01-03 |
| EP1406593A2 (en) | 2004-04-14 |
| WO2003000237A8 (en) | 2004-12-23 |
| JP4758607B2 (ja) | 2011-08-31 |
| US7163697B2 (en) | 2007-01-16 |
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