DE60235396D1 - 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung - Google Patents

3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung

Info

Publication number
DE60235396D1
DE60235396D1 DE60235396T DE60235396T DE60235396D1 DE 60235396 D1 DE60235396 D1 DE 60235396D1 DE 60235396 T DE60235396 T DE 60235396T DE 60235396 T DE60235396 T DE 60235396T DE 60235396 D1 DE60235396 D1 DE 60235396D1
Authority
DE
Germany
Prior art keywords
amido
derivatives
benzoxoxazole
manufacture
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60235396T
Other languages
English (en)
Inventor
Jin-Soo Lee
Seok-Hoon Ahn
Young-Goo Jin
Sang-Mi Jin
Sae-Kwang Ku
Jei-Man Rye
Yong-Ho Chung
Eun-Joo Kim
Sun-Ki Cho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dong Wha Pharm Co Ltd
Original Assignee
Dong Wha Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Wha Pharm Co Ltd filed Critical Dong Wha Pharm Co Ltd
Application granted granted Critical
Publication of DE60235396D1 publication Critical patent/DE60235396D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60235396T 2001-11-06 2002-11-05 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung Expired - Lifetime DE60235396D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020010069013A KR100789567B1 (ko) 2001-11-06 2001-11-06 3-아미도-1,2-벤조이소옥사졸 유도체, 그 염, 제조방법 및 용도
PCT/KR2002/002058 WO2003040113A1 (en) 2001-11-06 2002-11-05 3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof

Publications (1)

Publication Number Publication Date
DE60235396D1 true DE60235396D1 (de) 2010-04-01

Family

ID=19715763

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60235396T Expired - Lifetime DE60235396D1 (de) 2001-11-06 2002-11-05 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung

Country Status (9)

Country Link
US (1) US7291638B2 (de)
EP (1) EP1451163B1 (de)
JP (1) JP2005508987A (de)
KR (1) KR100789567B1 (de)
CN (1) CN1309711C (de)
AT (1) ATE457981T1 (de)
DE (1) DE60235396D1 (de)
ES (1) ES2338102T3 (de)
WO (1) WO2003040113A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8933236B2 (en) 2012-05-22 2015-01-13 Xenon Pharmaceuticals Inc. N-substituted benzamides and methods of use thereof
WO2006057507A1 (en) * 2004-11-23 2006-06-01 Dong Wha Pharm.Ind.Co., Ltd An oral preparation having improved bioavailability
DE102005038947A1 (de) 2005-05-18 2006-11-30 Grünenthal GmbH Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln
DE102005026194A1 (de) * 2005-06-06 2006-12-07 Grünenthal GmbH Substituierte N-Benzo[d]isoxazol-3-yl-amin-Derivate und deren Verwendung zur Herstellung von Arzneimitteln
AU2006279325B2 (en) * 2005-08-18 2013-06-27 Accelalox, Inc. Methods for bone treatment by modulating an arachidonic acid metabolic or signaling pathway
AU2006292224B2 (en) 2005-09-19 2013-08-01 Histogenics Corporation Cell-support matrix and a method for preparation thereof
WO2009105723A2 (en) * 2008-02-22 2009-08-27 Accelalox, Inc. Novel methods for bone treatment by modulating an arachidonic acid metabolic or signaling pathway
BR112014010271A2 (pt) 2011-10-31 2017-04-18 Xenon Pharmaceuticals Inc compostos de benzenossulfonamida e seu uso como agentes terapêuticos
EP2773641B1 (de) 2011-10-31 2017-09-27 Xenon Pharmaceuticals Inc. Biarylethersulfonamide und ihre verwendung als arzneimittel
CA2878478A1 (en) 2012-07-06 2014-01-09 Genentech, Inc. N-substituted benzamides and methods of use thereof
EP2968280A4 (de) 2013-03-14 2016-08-10 Genentech Inc Substituierte triazolopyridine und verfahren zur verwendung davon
RU2015143834A (ru) * 2013-03-15 2017-04-24 Дженентек, Инк. Замещенные бензоксазолы и способы их применения
CN105492430B (zh) * 2013-03-15 2017-10-10 基因泰克公司 取代的苯并噁唑及其使用方法
CA2931732A1 (en) 2013-11-27 2015-06-04 Genentech, Inc. Substituted benzamides and methods of use thereof
EP3166939B1 (de) 2014-07-07 2019-06-05 Genentech, Inc. Therapeutische verbindungen und verfahren zur verwendung davon
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
KR20180008761A (ko) 2015-05-22 2018-01-24 제넨테크, 인크. 치환된 벤즈아미드 및 이의 이용 방법
WO2017035271A1 (en) 2015-08-27 2017-03-02 Genentech, Inc. Therapeutic compounds and methods of use thereof
SG10202007787RA (en) 2015-09-28 2020-09-29 Genentech Inc Therapeutic compounds and methods of use thereof
WO2017091592A1 (en) 2015-11-25 2017-06-01 Genentech, Inc. Substituted benzamides useful as sodium channel blockers
EP3436432B1 (de) 2016-03-30 2021-01-27 Genentech, Inc. Substituierte benzamide und verfahren zur verwendung davon
GB2569711B (en) * 2016-09-09 2020-06-03 Walmart Apollo Llc Apparatus and method for monitoring a field
MX2019004232A (es) 2016-10-17 2019-08-01 Genentech Inc Compuestos terapéuticos y métodos para utilizarlos.
CN110546148A (zh) 2017-03-24 2019-12-06 基因泰克公司 作为钠通道抑制剂的4-哌啶-n-(嘧啶-4-基)色满-7-磺酰胺衍生物
WO2019165290A1 (en) 2018-02-26 2019-08-29 Genentech, Inc. Pyridine-sulfonamide compounds and their use against pain and related conditions
EP3774801A1 (de) 2018-03-30 2021-02-17 F. Hoffmann-La Roche AG Hydro-pyrido-verbindungen mit kondensierten ringen als natriumkanalinhibitoren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2737213B2 (ja) * 1989-03-10 1998-04-08 日産化学工業株式会社 ロイコトリエンｂ▲下４▼誘導体
JP3457669B2 (ja) * 1992-10-28 2003-10-20 富山化学工業株式会社 新規な１，２−ベンゾイソオキサゾール誘導体またはその塩，それらからなる脳保護剤
CN1074923C (zh) * 1993-11-19 2001-11-21 詹森药业有限公司 微囊密封的3-哌啶基取代的1,2-苯并异唑类和1,2-苯并异噻唑类
CA2278190A1 (en) 1997-02-04 1998-08-06 Hong-Suk Suh 3-amino-1,2-benzoisoxazole derivatives, process for preparation, and use thereof

Also Published As

Publication number Publication date
CN1578775A (zh) 2005-02-09
EP1451163B1 (de) 2010-02-17
EP1451163A4 (de) 2005-01-26
US20050020650A1 (en) 2005-01-27
JP2005508987A (ja) 2005-04-07
EP1451163A1 (de) 2004-09-01
ATE457981T1 (de) 2010-03-15
WO2003040113A1 (en) 2003-05-15
ES2338102T3 (es) 2010-05-04
CN1309711C (zh) 2007-04-11
KR100789567B1 (ko) 2007-12-28
KR20030038868A (ko) 2003-05-17
US7291638B2 (en) 2007-11-06

Similar Documents

Publication Publication Date Title
DE60235396D1 (de) 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung
SG166019A1 (en) Quinoline derivatives and use thereof as mycobacterial inhibitors
EP2423207A3 (de) 2-(zyklische amin)-pyrimidon-Derivate als TPK1-Hemmer
CY1111876T1 (el) Νεες πυρρολες με υπολiπiδaiμiκες και υποχοληστερολαιμικες δραστικοτητες, μεθοδος για την παρασκευη αυτων και φαρμακευτικες συνθεσεις που τις περιεχουν και η χρηση αυτων στην ιατρικη
IL177291A0 (en) Fused heterocyclic compounds and their use as metabotropic glutamate receptor antagonists
ATE420862T1 (de) 1,2-dihydropyridinverbindungen, verfahren zu deren herstellung und deren verwendung
NO341631B1 (no) Hydroksybenzamidderivater og deres anvendelse, fremgangsmåte for fremstilling og farmasøytiske sammensetninger
DK1534305T3 (da) Behandling af brusk-/knoglelidelser med vandoplöselige strontiumsalte
MY141255A (en) Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
PA8676301A1 (es) Metodos para sintetizar derivados de 6-alquilaminoquinolina
UA89123C2 (ru) Производные пиримидина для лечения абнормального роста клеток
MXPA05013474A (es) Derivados de quinolilamida como antagonistas de ccr-5.
MXPA05009611A (es) Piperidinas sustituidas como nuevos inhibidores de mdm2-p53.
IS8377A (is) Arýlindenópyridín og arýlindenópyrimidín og notkun þeirra sem mótlyf A2A viðtaka adenósíns
ATE374190T1 (de) Tetrahydrochinazolinderivate als cfr-antagonisten
ATE543803T1 (de) 3-ä2-(3-azylamino-2-oxo-2h-pyridin-1- yl)acetylaminoü-4-oxopentansäurederivate und deren verwendung als caspase-inhibitoren
JO2413B1 (en) Benzoxazine derivatives and their use
EA200501041A1 (ru) Замещенные производные 1-пиперидин-4-ил-4-пирролидин-3-илпиперазина и их применение в качестве антагонистов нейрокининов
DE50305693D1 (de) N-benzoylureido-zimts urederivate, verfahren zu deren herste llung und deren verwendung
BR0317487A (pt) O r-isÈmero de compostos de aminoácido beta como derivados de antagonistas de receptores de integrina
TNSN04024A1 (en) Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
CY1105550T1 (el) Μεμνο-πεπτιδια, μια διαδικασια για την παρασκευη και τη χρηση τους
TW200606154A (en) Mercaptoimidazoles as CCR2 receptor antagonists
DK1347965T3 (da) Hidtil ukendte desloratidinsalte, fremgangsmåde til syntese deraf samt farmaceutiske præparater deraf
NZ504298A (en) 2,3-methano-amino acid compounds for treating serine protease disorders

Legal Events

Date Code Title Description
8364 No opposition during term of opposition