DE60229287D1 - Pharmazeutische zubereitung zur oralen verwendung von heparin und seinen derivaten - Google Patents

Pharmazeutische zubereitung zur oralen verwendung von heparin und seinen derivaten

Info

Publication number
DE60229287D1
DE60229287D1 DE60229287T DE60229287T DE60229287D1 DE 60229287 D1 DE60229287 D1 DE 60229287D1 DE 60229287 T DE60229287 T DE 60229287T DE 60229287 T DE60229287 T DE 60229287T DE 60229287 D1 DE60229287 D1 DE 60229287D1
Authority
DE
Germany
Prior art keywords
heparin
derivatives
pharmaceutical preparation
oral use
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60229287T
Other languages
English (en)
Inventor
Mauro Ajani
Luigi Moro
Roberto Villa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cosmo Technologies Ltd
Original Assignee
Cosmo Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cosmo Technologies Ltd filed Critical Cosmo Technologies Ltd
Application granted granted Critical
Publication of DE60229287D1 publication Critical patent/DE60229287D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60229287T 2001-12-11 2002-12-03 Pharmazeutische zubereitung zur oralen verwendung von heparin und seinen derivaten Expired - Lifetime DE60229287D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001MI002599A ITMI20012599A1 (it) 2001-12-11 2001-12-11 Composizioni farmaceutiche per la somministrazione orale di eparina osuoi derivati, utili per la terapia di malattie infiammatorie dell'int
PCT/EP2002/013651 WO2003049721A1 (en) 2001-12-11 2002-12-03 Pharmaceutical compositions for the oral administration of heparin or derivatives thereof

Publications (1)

Publication Number Publication Date
DE60229287D1 true DE60229287D1 (de) 2008-11-20

Family

ID=11448679

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60229287T Expired - Lifetime DE60229287D1 (de) 2001-12-11 2002-12-03 Pharmazeutische zubereitung zur oralen verwendung von heparin und seinen derivaten

Country Status (18)

Country Link
US (1) US8642082B2 (de)
EP (2) EP1455761B1 (de)
JP (1) JP4634713B2 (de)
KR (2) KR101062687B1 (de)
CN (2) CN1258360C (de)
AT (1) ATE410148T1 (de)
AU (1) AU2002358082A1 (de)
CA (1) CA2465832C (de)
CY (1) CY1108625T1 (de)
DE (1) DE60229287D1 (de)
DK (2) DK1455761T3 (de)
ES (2) ES2386922T3 (de)
HK (1) HK1072181A1 (de)
IT (1) ITMI20012599A1 (de)
MX (1) MXPA04005710A (de)
PT (2) PT1992338E (de)
SI (1) SI1455761T1 (de)
WO (1) WO2003049721A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8895064B2 (en) 1999-06-14 2014-11-25 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
ATE251449T1 (de) 1999-06-14 2003-10-15 Cosmo Spa Geschmacksmaskierte orale pharmazeutische zusammensetzungen mit kontrollierter abgabe
US8257744B2 (en) * 2000-07-07 2012-09-04 Laboratorios Farmacéuticos Rovi, S.A. Pharmaceutical forms for the release of active compounds
EP2060253A1 (de) 2007-11-14 2009-05-20 Laboratorios Farmaceuticos Rovi, S.A. Pharmazeutische Formen zur Freisetzung von Wirkstoffen
SE0201922D0 (sv) * 2002-06-20 2002-06-20 Ltp Lipid Technologies Provide Koagulationshindrande komposition (Anticoagulant Composition)
ATE552004T1 (de) * 2005-11-30 2012-04-15 Istituto G Ronzoni Oral verabreichbare heparinderivate
CA2663548A1 (en) * 2006-09-12 2008-03-20 Cosmo Technologies Ltd Pharmaceutical compositions for the oral or rectal administration of protein substances
KR100837558B1 (ko) 2007-04-30 2008-06-12 (주)아모레퍼시픽 이중으로 안정된 세라마이드 나노 캡슐 포함 에멀젼조성물, 그의 제조방법 및 이를 이용한 피부 화장료 조성물
EP2213282A1 (de) 2009-01-30 2010-08-04 Laboratorios Farmaceuticos Rovi, S.A. Pharmazeutische Formen zur Freisetzung von Wirkstoffen
US8802156B2 (en) 2007-11-14 2014-08-12 Laboratorios Farmacéuticos Rovi, S.A. Pharmaceutical forms for the release of active compounds
KR101291813B1 (ko) 2011-04-27 2013-08-02 임승택 친수성이 증가된 덱스트린-세라마이드 복합체 및 이의 제조방법
US10154964B2 (en) 2011-09-07 2018-12-18 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
KR20200037574A (ko) 2018-10-01 2020-04-09 (주)우리비앤비 헤파린을 포함하는 탈모방지용 화장료 조성물
EP3791884A1 (de) * 2019-09-16 2021-03-17 Oskar Bunz Kombination aus heparin und magnesiumsalz zur behandlung viraler infektionen
CN110585164A (zh) * 2019-10-08 2019-12-20 苏州弘森药业股份有限公司 一种艾司奥美拉唑镁碳酸氢钠胶囊的制作方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6054313A (ja) 1983-09-01 1985-03-28 Terumo Corp 腸管吸収性ヘパリン組成物
JP2893191B2 (ja) 1988-11-08 1999-05-17 武田薬品工業株式会社 放出制御性マトリックス剤
IE61651B1 (en) 1990-07-04 1994-11-16 Zambon Spa Programmed release oral solid pharmaceutical dosage form
US5665379A (en) 1990-09-28 1997-09-09 Pharmacia & Upjohn Aktiebolag Lipid particle forming matrix, preparation and use thereof
PT621032E (pt) 1993-04-23 2001-01-31 Novartis Ag Dispositivo de distribuicao de libertacao controlada de farmaco
US5665370A (en) * 1995-02-22 1997-09-09 Temple University Of The Commonwealth System Of Higher Education Compositions containing cockroach aggregation pheromones, their production and uses
FR2763848B1 (fr) * 1997-05-28 2000-01-28 Rhone Poulenc Rorer Sa Utilisation des heparines de bas poids moleculaire pour la prevention et le traitement du trauma du systeme nerveux central
IT1298575B1 (it) * 1998-02-06 2000-01-12 Vectorpharma Int Composizioni farmaceutiche in forma di nanoparticelle comprendenti sostanze lipidiche e sostanze antifiliche e relativo processo di
US6423345B2 (en) * 1998-04-30 2002-07-23 Acusphere, Inc. Matrices formed of polymer and hydrophobic compounds for use in drug delivery
WO2000048589A1 (en) 1999-02-22 2000-08-24 Emisphere Holdings, Inc. Solid oral dosage form containing heparin or a heparinoid in combination with a carrier
ITMI991316A1 (it) 1999-06-14 2000-12-14 Cip Ninety Two 92 S A Composizioni farmaceutiche orali a rilascio modificato di mesalazina
AU1594801A (en) 1999-11-12 2001-06-06 Emisphere Technologies, Inc. Liquid heparin formulation
EP1392272B1 (de) * 2001-05-11 2014-08-06 Merrion Research III Limited Permeationsverbesserer

Also Published As

Publication number Publication date
JP2005511718A (ja) 2005-04-28
KR100984801B1 (ko) 2010-10-04
CA2465832A1 (en) 2003-06-19
ITMI20012599A1 (it) 2003-06-11
SI1455761T1 (sl) 2009-02-28
CA2465832C (en) 2011-06-28
CN1258360C (zh) 2006-06-07
KR20090065556A (ko) 2009-06-22
KR20040063989A (ko) 2004-07-15
DK1992338T3 (da) 2013-03-25
EP1992338A3 (de) 2009-08-12
ATE410148T1 (de) 2008-10-15
EP1992338B1 (de) 2012-06-27
EP1455761A1 (de) 2004-09-15
JP4634713B2 (ja) 2011-02-16
US20050020539A1 (en) 2005-01-27
CN1839877A (zh) 2006-10-04
CN100490823C (zh) 2009-05-27
HK1072181A1 (en) 2005-08-19
EP1992338A2 (de) 2008-11-19
MXPA04005710A (es) 2004-12-06
PT1455761E (pt) 2008-12-17
CN1599600A (zh) 2005-03-23
DK1455761T3 (da) 2009-01-12
ES2386922T3 (es) 2012-09-06
CY1108625T1 (el) 2014-04-09
ES2312652T3 (es) 2009-03-01
DK1992338T5 (da) 2013-04-08
AU2002358082A1 (en) 2003-06-23
KR101062687B1 (ko) 2011-09-06
EP1455761B1 (de) 2008-10-08
US8642082B2 (en) 2014-02-04
WO2003049721A1 (en) 2003-06-19
PT1992338E (pt) 2012-07-30

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Legal Events

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