DE60228875D1 - Biologisch abbaubare amin-enthaltende polyorthoester und blockcopolymere daraus - Google Patents

Biologisch abbaubare amin-enthaltende polyorthoester und blockcopolymere daraus

Info

Publication number
DE60228875D1
DE60228875D1 DE60228875T DE60228875T DE60228875D1 DE 60228875 D1 DE60228875 D1 DE 60228875D1 DE 60228875 T DE60228875 T DE 60228875T DE 60228875 T DE60228875 T DE 60228875T DE 60228875 D1 DE60228875 D1 DE 60228875D1
Authority
DE
Germany
Prior art keywords
block copolymers
polyorthoesters
biodegradable amino
hydrophobic
biodegradable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60228875T
Other languages
English (en)
Inventor
Steven Y Ng
Jorge Heller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heron Therapeutics LLC
Original Assignee
AP Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AP Pharma Inc filed Critical AP Pharma Inc
Application granted granted Critical
Publication of DE60228875D1 publication Critical patent/DE60228875D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/40—Polyesters derived from ester-forming derivatives of polycarboxylic acids or of polyhydroxy compounds, other than from esters thereof
    • C08G63/42—Cyclic ethers; Cyclic carbonates; Cyclic sulfites; Cyclic orthoesters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/668—Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/002—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from unsaturated compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
    • C08G2650/38—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type containing oxygen in addition to the ether group
    • C08G2650/42—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type containing oxygen in addition to the ether group containing orthoester groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Polyethers (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE60228875T 2001-11-16 2002-11-15 Biologisch abbaubare amin-enthaltende polyorthoester und blockcopolymere daraus Expired - Fee Related DE60228875D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/991,537 US6524606B1 (en) 2001-11-16 2001-11-16 Bioerodible polyorthoesters containing amine groups
PCT/US2002/036775 WO2003044076A1 (en) 2001-11-16 2002-11-15 Bioerodible poly(ortho esters) containing amine groups, and block copolymers containing them

Publications (1)

Publication Number Publication Date
DE60228875D1 true DE60228875D1 (de) 2008-10-23

Family

ID=25537313

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60228875T Expired - Fee Related DE60228875D1 (de) 2001-11-16 2002-11-15 Biologisch abbaubare amin-enthaltende polyorthoester und blockcopolymere daraus

Country Status (10)

Country Link
US (3) US6524606B1 (de)
EP (1) EP1448666B1 (de)
JP (1) JP2005509709A (de)
KR (1) KR20040066818A (de)
AT (1) ATE407963T1 (de)
AU (1) AU2002352743B2 (de)
CA (1) CA2463179A1 (de)
DE (1) DE60228875D1 (de)
ES (1) ES2314118T3 (de)
WO (1) WO2003044076A1 (de)

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CA2463179A1 (en) 2003-05-30
WO2003044076A8 (en) 2004-07-29
US6946145B2 (en) 2005-09-20
ES2314118T3 (es) 2009-03-16
JP2005509709A (ja) 2005-04-14
US20040146550A1 (en) 2004-07-29
AU2002352743B2 (en) 2008-10-23
ATE407963T1 (de) 2008-09-15
US6667371B2 (en) 2003-12-23
EP1448666B1 (de) 2008-09-10
WO2003044076A1 (en) 2003-05-30
KR20040066818A (ko) 2004-07-27
AU2002352743A1 (en) 2003-06-10
US6524606B1 (en) 2003-02-25
EP1448666A1 (de) 2004-08-25

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