DE60225702D1 - Strontium verbindung zur behandlung von sub-dermalem weichteilschmerz - Google Patents

Strontium verbindung zur behandlung von sub-dermalem weichteilschmerz

Info

Publication number
DE60225702D1
DE60225702D1 DE60225702T DE60225702T DE60225702D1 DE 60225702 D1 DE60225702 D1 DE 60225702D1 DE 60225702 T DE60225702 T DE 60225702T DE 60225702 T DE60225702 T DE 60225702T DE 60225702 D1 DE60225702 D1 DE 60225702D1
Authority
DE
Germany
Prior art keywords
treatment
sub
strontium
connection
soft part
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60225702T
Other languages
English (en)
Other versions
DE60225702T2 (de
Inventor
Egil Jellum
Bjorn Jarl Fagerlund
Clas Magne Kjolberg
Jo Klaveness
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SantoSolve AS
Original Assignee
SantoSolve AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SantoSolve AS filed Critical SantoSolve AS
Publication of DE60225702D1 publication Critical patent/DE60225702D1/de
Application granted granted Critical
Publication of DE60225702T2 publication Critical patent/DE60225702T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Inorganic Insulating Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Surgical Instruments (AREA)
DE60225702T 2001-09-28 2002-09-27 Strontium verbindung zur behandlung von sub-dermalem weichteilschmerz Expired - Lifetime DE60225702T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20014746 2001-09-28
NO20014746A NO20014746D0 (no) 2001-09-28 2001-09-28 Smertelindrende middel
PCT/GB2002/004418 WO2003028742A1 (en) 2001-09-28 2002-09-27 Strontium compound for treatment of sub-dermal soft tissue pain

Publications (2)

Publication Number Publication Date
DE60225702D1 true DE60225702D1 (de) 2008-04-30
DE60225702T2 DE60225702T2 (de) 2008-11-20

Family

ID=19912876

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60225702T Expired - Lifetime DE60225702T2 (de) 2001-09-28 2002-09-27 Strontium verbindung zur behandlung von sub-dermalem weichteilschmerz

Country Status (12)

Country Link
US (4) US7241460B2 (de)
EP (2) EP1429792B1 (de)
JP (1) JP4750358B2 (de)
CN (2) CN1981780A (de)
AT (1) ATE389411T1 (de)
CA (1) CA2499814C (de)
DE (1) DE60225702T2 (de)
DK (1) DK1429792T3 (de)
ES (1) ES2303860T3 (de)
NO (1) NO20014746D0 (de)
PT (1) PT1429792E (de)
WO (1) WO2003028742A1 (de)

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NO20014746D0 (no) * 2001-09-28 2001-09-28 Clas M Kjoelberg Smertelindrende middel
NZ540318A (en) * 2002-10-31 2007-09-28 Umd Inc Therapeutic compositions for drug delivery to and through covering epithelia
EP2995312A1 (de) 2003-03-27 2016-03-16 SantoSolve AS Entzündungshemmende zusammensetzung auf der basis von strontiumverbindungen
CA2524610C (en) * 2003-05-07 2014-03-25 Osteologix A/S Strontium combinations for prophylaxis/treatment of cartilage and/or bone conditions
PL1534305T3 (pl) * 2003-05-07 2007-03-30 Osteologix As Leczenie zaburzeń chrząstek i kości solami strontu rozpuszczalnymi w wodzie
EP1622629B1 (de) * 2003-05-07 2013-07-10 Osteologix A/S Strontiumzubereitung mit kontrollierter Freisetzung
EP1523985B1 (de) * 2003-10-17 2010-03-10 Oy Neurofood Ab Nicht-radioaktives Strontiummittel zur Behandlung von Krebs
SI1732575T1 (sl) * 2004-02-26 2011-05-31 Osteologix As Spojine, ki vsebujejo stroncij, za uporabo pri preprečevanju ali zdravljenju nekrotičnih kostnih stanj
KR101165614B1 (ko) 2004-02-26 2012-07-18 오스테올로지스 에이에스 괴사성 골 질환의 예방 또는 치료에 사용하기 위한스트론튬 함유 화합물
EP1744770A2 (de) * 2004-05-06 2007-01-24 Osteologix A/S Schnelle synthesemethoden mit hoher ausbeute zur herstellung von metallorganischen salzen
CA2570389A1 (en) * 2004-06-17 2005-12-29 Osteologix A/S Treatments comprising strontium for rheumatic and arthritic diseases and pain
CA2570503A1 (en) * 2004-06-17 2005-12-29 Osteologix A/S A method of improving the medical treatment of pain
LT2801354T (lt) 2004-10-08 2017-06-26 Forward Pharma A/S Kontroliuojamo atpalaidavimo farmacinės kompozicijos, apimančios fumaro rūgšties esterį
GB2425060A (en) * 2005-03-24 2006-10-18 Santosolve As Strontium compounds in cosmetics
US20090137678A1 (en) * 2005-07-06 2009-05-28 Stephan Christgau High yield synthesis methods for producing organic salts of strontium
EP2029184B1 (de) 2006-05-26 2011-02-23 Baxter International Inc. Injizierbare fibrin-zusammensetzung zur knochenverstärkung
JP5907656B2 (ja) * 2007-04-23 2016-04-26 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ ストロンチウム化合物を含むフィブリン組成物
US8906420B2 (en) 2009-01-09 2014-12-09 Forward Pharma A/S Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix
CN101973922B (zh) * 2009-05-27 2013-01-23 天津和美生物技术有限公司 阿伐他汀半锶盐多晶型物、其制备和作为HMG-CoA酶抑制剂的应用
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MX365427B (es) 2011-05-03 2019-06-03 Aponia Laboratories Inc Composiciones transdermicas de ibuprofeno y metodos de uso de las mismas.
EP2530068A1 (de) 2011-05-31 2012-12-05 Lacer, S.A. Neue Strontiumsalze, deren Synthese und Verwendung bei der Behandlung von Osteoporose
US9480704B2 (en) 2012-03-21 2016-11-01 Cosmederm Bioscience, Inc. Topically administered strontium-containing complexes for treating pain, pruritis and inflammation
EP2827847B1 (de) * 2012-03-21 2022-09-14 Galleon Labs LLC Topisch anwendbare strontiumhaltige komplexe zur behandlung von schmerzen, juckreiz und entzündungen
WO2016141219A1 (en) * 2015-03-05 2016-09-09 Cosmederm Bioscience, Inc. Strontium based compositions and formulations for pain, pruritus, and inflammation
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Also Published As

Publication number Publication date
DK1429792T3 (da) 2008-07-14
US20150265649A1 (en) 2015-09-24
EP1741436A1 (de) 2007-01-10
WO2003028742A1 (en) 2003-04-10
JP4750358B2 (ja) 2011-08-17
NO20014746D0 (no) 2001-09-28
CN100415247C (zh) 2008-09-03
US7241460B2 (en) 2007-07-10
DE60225702T2 (de) 2008-11-20
CA2499814A1 (en) 2003-04-10
EP1429792A1 (de) 2004-06-23
PT1429792E (pt) 2008-07-01
US20070237836A1 (en) 2007-10-11
ES2303860T3 (es) 2008-09-01
ATE389411T1 (de) 2008-04-15
CN1585646A (zh) 2005-02-23
US20050013877A1 (en) 2005-01-20
US20110038953A1 (en) 2011-02-17
CN1981780A (zh) 2007-06-20
JP2005507396A (ja) 2005-03-17
US9050312B2 (en) 2015-06-09
CA2499814C (en) 2011-07-26
EP1429792B1 (de) 2008-03-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KUDLEK & GRUNERT PATENTANWAELTE PARTNERSCHAFT, 803