DE69918145D1 - Verwendung von diltiazem zur behandlung von pathologien der netzhaut - Google Patents

Verwendung von diltiazem zur behandlung von pathologien der netzhaut

Info

Publication number
DE69918145D1
DE69918145D1 DE69918145T DE69918145T DE69918145D1 DE 69918145 D1 DE69918145 D1 DE 69918145D1 DE 69918145 T DE69918145 T DE 69918145T DE 69918145 T DE69918145 T DE 69918145T DE 69918145 D1 DE69918145 D1 DE 69918145D1
Authority
DE
Germany
Prior art keywords
diltiazem
retal
treatment
skin pathologies
pathologies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69918145T
Other languages
English (en)
Other versions
DE69918145T2 (de
Inventor
Serge Picaud
Maria Frasson
Jose Sahel
Henri Dreyfus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Universite Louis Pasteur Strasbourg I
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Louis Pasteur Strasbourg I, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Universite Louis Pasteur Strasbourg I
Application granted granted Critical
Publication of DE69918145D1 publication Critical patent/DE69918145D1/de
Publication of DE69918145T2 publication Critical patent/DE69918145T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Prostheses (AREA)
DE69918145T 1998-10-02 1999-10-01 Verwendung von diltiazem zur behandlung von pathologien der netzhaut Expired - Fee Related DE69918145T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9812364 1998-10-02
FR9812364A FR2784030B1 (fr) 1998-10-02 1998-10-02 Utilisation de bloqueurs des canaux calciques et/ou cgmp-dependants pour le traitement de pathologies de la retine
PCT/FR1999/002346 WO2000020006A1 (fr) 1998-10-02 1999-10-01 Utilisation du diltiazem pour le traitement de pathologies de la retine

Publications (2)

Publication Number Publication Date
DE69918145D1 true DE69918145D1 (de) 2004-07-22
DE69918145T2 DE69918145T2 (de) 2005-08-11

Family

ID=9531128

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69918145T Expired - Fee Related DE69918145T2 (de) 1998-10-02 1999-10-01 Verwendung von diltiazem zur behandlung von pathologien der netzhaut

Country Status (9)

Country Link
US (1) US6716835B1 (de)
EP (1) EP1117408B9 (de)
JP (1) JP2002526411A (de)
AT (1) ATE269085T1 (de)
AU (1) AU5870099A (de)
DE (1) DE69918145T2 (de)
ES (1) ES2219060T3 (de)
FR (1) FR2784030B1 (de)
WO (1) WO2000020006A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2823221B1 (fr) 2001-04-06 2004-04-02 Univ Pasteur Sequences associees a la degenerescence retinienne et applications
US7445777B2 (en) 2002-10-01 2008-11-04 Paola Ammannati Enzymatic treatment of retinitis pigmentosis
CA2995880C (en) 2009-01-16 2021-01-05 Exelixis, Inc. Processes for preparing n-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
US20110021974A1 (en) * 2010-10-05 2011-01-27 Shantha Totada R Retinitis pigmentosa treatment and prophalaxis
CN103748154B (zh) 2011-07-15 2015-11-25 索尔维特殊聚合物意大利有限公司 用于多层组件的氟聚合物组合物
ES2689136T3 (es) 2013-07-31 2018-11-08 Novartis Ag Nuevos vectores de selección y métodos de selección de células hospedadoras eucariotas
JP6954582B2 (ja) * 2016-12-22 2021-10-27 国立大学法人滋賀医科大学 医薬組成物
FR3081325B1 (fr) 2018-05-23 2020-10-09 Univ Claude Bernard Lyon Diltiazem pour son utilisation dans le traitement des infections microbiennes
WO2020123312A1 (en) * 2018-12-09 2020-06-18 Weinberg Assa Method to prevent and treat macular degeneration by vasodilators
FR3106055B1 (fr) 2020-01-13 2022-01-28 Centre Nat Rech Scient Combinaison de diltiazem et autres agents antiviraux
FR3108033B1 (fr) 2020-03-10 2023-04-21 Univ Claude Bernard Lyon COMPOSES ANTIVIRAUX ET LEURS COMBINAISONS POUR TRAITER L’INFECTION VIRALE PAR LE SARS-CoV-2

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990006118A1 (en) * 1988-12-05 1990-06-14 Houston Biotechnology Incorporated Therapeutic use of dihydropyrimidones and benzazepine and benzothiazepine derivatives in retinal or optic nerve dysfunction
US5597809A (en) * 1994-06-23 1997-01-28 Massachusetts Eye & Ear Infirmary Treatment of optic neuritis
US5431907A (en) * 1994-08-03 1995-07-11 Abelson; Mark B. Treatment of vascular disorders of the posterior segment of the eye by topical administration of calcium channel blocking agents
DE19718826A1 (de) * 1997-05-05 1998-11-12 Marion S Dr Eckmiller Verwendung biologisch aktiver Wirkstoffe zum Beeinflussen des Extrazellulär-Raumes von Sinneszellen und Verfahren zur Wirkstoff-Administrationssteuerung

Also Published As

Publication number Publication date
EP1117408B1 (de) 2004-06-16
US6716835B1 (en) 2004-04-06
AU5870099A (en) 2000-04-26
JP2002526411A (ja) 2002-08-20
EP1117408A1 (de) 2001-07-25
ATE269085T1 (de) 2004-07-15
EP1117408B9 (de) 2004-11-10
DE69918145T2 (de) 2005-08-11
ES2219060T3 (es) 2004-11-16
FR2784030A1 (fr) 2000-04-07
FR2784030B1 (fr) 2002-12-20
WO2000020006A1 (fr) 2000-04-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M

8339 Ceased/non-payment of the annual fee