DE60225559D1 - Vorrichtung und verfahren für kontinuierliche zellkultur - Google Patents

Vorrichtung und verfahren für kontinuierliche zellkultur

Info

Publication number
DE60225559D1
DE60225559D1 DE60225559T DE60225559T DE60225559D1 DE 60225559 D1 DE60225559 D1 DE 60225559D1 DE 60225559 T DE60225559 T DE 60225559T DE 60225559 T DE60225559 T DE 60225559T DE 60225559 D1 DE60225559 D1 DE 60225559D1
Authority
DE
Germany
Prior art keywords
sample
path
cell culture
continuous cell
detector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60225559T
Other languages
English (en)
Other versions
DE60225559T2 (de
Inventor
Brian Norman Ellison
Colin Gibson
Norman Arthur Grant
Gerard Joseph Hyland
David B Lloyd
John Thomas Magee
David Tallis Pooley
William Ralph Stewart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University College Cardiff Consultants Ltd
Cardiff University
Original Assignee
University College Cardiff Consultants Ltd
Cardiff University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University College Cardiff Consultants Ltd, Cardiff University filed Critical University College Cardiff Consultants Ltd
Publication of DE60225559D1 publication Critical patent/DE60225559D1/de
Application granted granted Critical
Publication of DE60225559T2 publication Critical patent/DE60225559T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N22/00—Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Electromagnetism (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
DE60225559T 2001-07-19 2002-07-19 Vorrichtung und verfahren für kontinuierliche zellkultur Expired - Lifetime DE60225559T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0117715.3A GB0117715D0 (en) 2001-07-19 2001-07-19 Microwave biochemical analysis
GB0117715 2001-07-19
PCT/GB2002/003330 WO2003008532A1 (en) 2001-07-19 2002-07-19 Apparatus and method for analysing a biological sample in response to microwave radiation

Publications (2)

Publication Number Publication Date
DE60225559D1 true DE60225559D1 (de) 2008-04-24
DE60225559T2 DE60225559T2 (de) 2009-04-02

Family

ID=9918876

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60225559T Expired - Lifetime DE60225559T2 (de) 2001-07-19 2002-07-19 Vorrichtung und verfahren für kontinuierliche zellkultur

Country Status (11)

Country Link
US (2) US20040175294A1 (de)
EP (2) EP1409637B1 (de)
JP (2) JP4260621B2 (de)
AT (1) ATE389009T1 (de)
AU (1) AU2002319453B9 (de)
BR (1) BR0211249A (de)
CA (1) CA2454293A1 (de)
DE (1) DE60225559T2 (de)
GB (1) GB0117715D0 (de)
NZ (1) NZ530665A (de)
WO (1) WO2003008532A1 (de)

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US6914423B2 (en) 2000-09-05 2005-07-05 Cascade Microtech, Inc. Probe station
US6965226B2 (en) 2000-09-05 2005-11-15 Cascade Microtech, Inc. Chuck for holding a device under test
DE20114544U1 (de) 2000-12-04 2002-02-21 Cascade Microtech, Inc., Beaverton, Oreg. Wafersonde
AU2002327490A1 (en) 2001-08-21 2003-06-30 Cascade Microtech, Inc. Membrane probing system
GB0307352D0 (en) 2003-03-29 2003-05-07 Qinetiq Ltd Improvements in and relating to the analysis of compounds
US20120221256A1 (en) * 2003-03-29 2012-08-30 Midas Mediscience Functional characterization of biological samples
US7492172B2 (en) 2003-05-23 2009-02-17 Cascade Microtech, Inc. Chuck for holding a device under test
US7057404B2 (en) 2003-05-23 2006-06-06 Sharp Laboratories Of America, Inc. Shielded probe for testing a device under test
US7250626B2 (en) 2003-10-22 2007-07-31 Cascade Microtech, Inc. Probe testing structure
JP2007517231A (ja) 2003-12-24 2007-06-28 カスケード マイクロテック インコーポレイテッド アクティブ・ウェハプローブ
US7187188B2 (en) 2003-12-24 2007-03-06 Cascade Microtech, Inc. Chuck with integrated wafer support
DE102004010217A1 (de) * 2004-02-27 2005-09-15 Carl Zeiss Jena Gmbh Anordnung und Verfahren zur spektroskopischen Bestimmung der Bestandteile und Konzentrationen pumpfähiger organischer Verbindungen
KR20070058522A (ko) 2004-09-13 2007-06-08 캐스케이드 마이크로테크 인코포레이티드 양측 프루빙 구조
JP2006174828A (ja) * 2004-11-29 2006-07-06 Olympus Corp 生体試料培養観察システム、インキュベータボックス、供給手段、および培養容器
US7535247B2 (en) 2005-01-31 2009-05-19 Cascade Microtech, Inc. Interface for testing semiconductors
US7656172B2 (en) 2005-01-31 2010-02-02 Cascade Microtech, Inc. System for testing semiconductors
EP1856239A1 (de) * 2005-02-23 2007-11-21 Alfred Michael Vegvary Überwachungssystem zur wahrnehmung von mikroorganismen
GB0504284D0 (en) 2005-03-02 2005-04-06 Boc Group Plc Conveyor system
US20060219941A1 (en) * 2005-03-29 2006-10-05 Clifford Edward T Bubble type radiation detectors having automated read-out
ITMI20050693A1 (it) * 2005-04-19 2006-10-20 C N R Consiglio Naz Delle Ricerche Apparecchiatura per la coltura di cellule eucariotiche e-o procariotiche
GB0510709D0 (en) 2005-05-26 2005-06-29 Cymtox Ltd Water monitoring system
US7525102B1 (en) * 2005-10-03 2009-04-28 Sparta, Inc. Agent detection in the presence of background clutter
DE102006022307A1 (de) * 2006-05-11 2007-11-15 Respironics Novametrix, LLC, Wallingford Einwegbioreaktor mit Sensoranordnung
US7403028B2 (en) 2006-06-12 2008-07-22 Cascade Microtech, Inc. Test structure and probe for differential signals
US7723999B2 (en) 2006-06-12 2010-05-25 Cascade Microtech, Inc. Calibration structures for differential signal probing
US7764072B2 (en) 2006-06-12 2010-07-27 Cascade Microtech, Inc. Differential signal probing system
US20080012578A1 (en) * 2006-07-14 2008-01-17 Cascade Microtech, Inc. System for detecting molecular structure and events
CN101182100B (zh) * 2006-11-13 2011-07-20 亚洲光学股份有限公司 具有微结构的玻璃模造模仁的制作方法及玻璃模造模仁
US8014959B2 (en) * 2007-05-07 2011-09-06 Sparta, Inc. Population of background suppression lists from limited data in agent detection systems
US7876114B2 (en) 2007-08-08 2011-01-25 Cascade Microtech, Inc. Differential waveguide probe
US9952296B2 (en) * 2007-12-21 2018-04-24 Koninklijke Philip N.V. Magnetic resonance safety monitoring systems and methods
US7888957B2 (en) 2008-10-06 2011-02-15 Cascade Microtech, Inc. Probing apparatus with impedance optimized interface
NL2002196C2 (en) * 2008-11-11 2010-05-17 Avantium Int Bv SAMPLE ANALYZES APPARATUS AND A METHOD OR ANALYZING A SAMPLE.
US8410806B2 (en) 2008-11-21 2013-04-02 Cascade Microtech, Inc. Replaceable coupon for a probing apparatus
US8319503B2 (en) 2008-11-24 2012-11-27 Cascade Microtech, Inc. Test apparatus for measuring a characteristic of a device under test
US8834684B2 (en) * 2009-04-14 2014-09-16 Rf Thummin Technologies, Inc. Method and apparatus for excitation of resonances in molecules
CA2830480A1 (en) 2010-03-17 2011-09-22 Rf Thummim Technologies, Inc. Method and apparatus for electromagnetically producing a disturbance in a medium with simultaneous resonance of acoustic waves created by the disturbance
CN102305800B (zh) * 2011-07-29 2013-05-08 华南理工大学 基于超宽带的易燃液体检测方法
CN102519898B (zh) * 2011-12-29 2013-07-10 上海智城分析仪器制造有限公司 单光源检测摇床发酵液体的装置
JP6227355B2 (ja) * 2013-09-27 2017-11-08 スタンレー電気株式会社 水素製造装置
TWI512285B (zh) * 2014-03-18 2015-12-11 Univ Kun Shan A method for measuring the number of cells and measuring the number of cells with a precision counting function
JP6228282B1 (ja) * 2016-09-27 2017-11-08 株式会社協和医療器 菌培養検査装置及び菌培養検査方法
US11455298B2 (en) 2019-02-06 2022-09-27 Parsons Corporation Goal-directed semantic search
US11922252B1 (en) * 2020-01-14 2024-03-05 Oceanit Laboratories, Inc. Metamaterials technology for ore tracking
CN111349559B (zh) * 2020-03-13 2022-10-14 中国人民解放军军事科学院军事医学研究院 一种小型宽带微波生物效应照射装置
WO2022053953A1 (en) * 2020-09-09 2022-03-17 Know Labs, Inc. Systems and methods for analyzing in vitro flowing fluids and determining variability in a state of a medium

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US4327180A (en) * 1979-09-14 1982-04-27 Board Of Governors, Wayne State Univ. Method and apparatus for electromagnetic radiation of biological material
US4337648A (en) * 1980-11-03 1982-07-06 Jodon Engineering Associates, Inc. Dual probe coupler
FI831936A0 (fi) * 1983-05-30 1983-05-30 Labsystems Oy Anordning foer maetning av fluorescens, turbiditet, luminescens eller absorption
US5089385A (en) * 1987-06-01 1992-02-18 The United States Of America As Represented By The Secretary Of The Air Force Method of culturing cells in a flow-through cell cultivation system
US5028541A (en) * 1987-06-01 1991-07-02 The United States Of America As Represented By The Secretary Of The Air Force Flow-through cell cultivation system
US4948975A (en) * 1988-09-08 1990-08-14 The United States Of America As Represented By The Secretary Of The Air Force Quantitative luminescence imaging system
JPH02119772A (ja) * 1988-10-29 1990-05-07 Shimadzu Corp 細胞培養装置
US5150061A (en) * 1989-05-23 1992-09-22 Institut Francais Du Petrole Method and device for measuring the qualities of a multiphase fluid
US5144224A (en) * 1991-04-01 1992-09-01 Larsen Lawrence E Millimeter wave flow cytometer
US5644244A (en) * 1991-06-21 1997-07-01 Texaco Inc. Method for analyzing a petroleum stream
GB9119382D0 (en) * 1991-09-11 1991-10-23 Knight Scient Ltd Apparatus for monitoring liquids
DE4211362C2 (de) * 1992-04-04 1995-04-20 Berthold Lab Prof Dr Vorrichtung zur Bestimmung von Materialparametern durch Mikrowellenmessungen
US5759847A (en) * 1995-07-14 1998-06-02 Difco Laboratories System and apparatus for automatically transferring media
GB2303916B (en) * 1995-07-29 1999-03-03 Siemens Plc Improvements in or relating to aqueous sample testing apparatus
US6122042A (en) * 1997-02-07 2000-09-19 Wunderman; Irwin Devices and methods for optically identifying characteristics of material objects
FR2771508B1 (fr) * 1997-11-26 2000-11-03 Pasteur Institut Appareil et procede de mesure de proprietes optiques par retroaction
ATE426456T1 (de) * 1998-05-01 2009-04-15 Gen Probe Inc Automatische diagnostische analysevorrichtung
AU8023500A (en) * 1999-10-13 2001-04-23 Mds Sciex System and method for detecting and identifying molecular events in a test sample

Also Published As

Publication number Publication date
BR0211249A (pt) 2004-07-27
AU2002319453B9 (en) 2009-07-30
JP4260621B2 (ja) 2009-04-30
JP2004535811A (ja) 2004-12-02
EP1409637A1 (de) 2004-04-21
CA2454293A1 (en) 2003-01-30
ATE389009T1 (de) 2008-03-15
NZ530665A (en) 2006-10-27
GB0117715D0 (en) 2001-09-12
EP1892287A2 (de) 2008-02-27
DE60225559T2 (de) 2009-04-02
US20040175294A1 (en) 2004-09-09
JP2009136286A (ja) 2009-06-25
WO2003008532A1 (en) 2003-01-30
EP1409637B1 (de) 2008-03-12
EP1892287A3 (de) 2008-04-09
US20090269836A1 (en) 2009-10-29
AU2002319453B2 (en) 2008-04-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition