DE60221550T2 - Methode zur bestimmung der zellzyklusposition - Google Patents

Methode zur bestimmung der zellzyklusposition Download PDF

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Publication number
DE60221550T2
DE60221550T2 DE60221550T DE60221550T DE60221550T2 DE 60221550 T2 DE60221550 T2 DE 60221550T2 DE 60221550 T DE60221550 T DE 60221550T DE 60221550 T DE60221550 T DE 60221550T DE 60221550 T2 DE60221550 T2 DE 60221550T2
Authority
DE
Germany
Prior art keywords
cell
cell cycle
reporter
construct
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60221550T
Other languages
German (de)
English (en)
Other versions
DE60221550D1 (de
Inventor
Jonathon Noe Welcome/Canc PINES
Nicholas Amersham Biosciences UK Ltd Cardiff THOMAS
Anne Elizabeth Amersham Biosciences Cardiff JONES
Ian David Amersham Biosciences UK Lt Cardiff GOODYER
Michael John Amersham Biosciences UK Cardiff FRANCIS
Rahman Aziz Amersham Biosciences UK Cardiff ISMAIL
Jonathan Mark Amersham Biosciences U Cardiff KENDALL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare UK Ltd
Cancer Research Technology Ltd
Original Assignee
GE Healthcare UK Ltd
Cancer Research Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare UK Ltd, Cancer Research Technology Ltd filed Critical GE Healthcare UK Ltd
Publication of DE60221550D1 publication Critical patent/DE60221550D1/de
Application granted granted Critical
Publication of DE60221550T2 publication Critical patent/DE60221550T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Fuel Cell (AREA)
DE60221550T 2001-10-05 2002-09-12 Methode zur bestimmung der zellzyklusposition Expired - Lifetime DE60221550T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0123856.7A GB0123856D0 (en) 2001-10-05 2001-10-05 Method for determining cell cycle position
GB0123856 2001-10-05
PCT/GB2002/004258 WO2003031612A2 (en) 2001-10-05 2002-09-12 Method for determining cell cycle position

Publications (2)

Publication Number Publication Date
DE60221550D1 DE60221550D1 (de) 2007-09-13
DE60221550T2 true DE60221550T2 (de) 2008-04-17

Family

ID=9923245

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60221550T Expired - Lifetime DE60221550T2 (de) 2001-10-05 2002-09-12 Methode zur bestimmung der zellzyklusposition

Country Status (11)

Country Link
US (2) US7235401B2 (enExample)
EP (1) EP1432819B1 (enExample)
JP (1) JP4607454B2 (enExample)
AT (1) ATE368753T1 (enExample)
AU (1) AU2002326036B2 (enExample)
CA (1) CA2461133C (enExample)
DE (1) DE60221550T2 (enExample)
ES (1) ES2290326T3 (enExample)
GB (1) GB0123856D0 (enExample)
IL (1) IL160908A0 (enExample)
WO (1) WO2003031612A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2401431B (en) * 2003-04-02 2005-04-27 Amersham Biosciences Uk Ltd Method of, and computer software for, classification of cells into subpopulations
GB0307684D0 (en) * 2003-04-02 2003-05-07 Amersham Biosciences Uk Ltd Determining cell cycle phase data
EP1624748A4 (en) * 2003-05-08 2009-01-07 Health Research Inc TRANSGENIC ANIMAL MODEL FOR STEM OR TRANSGENIC CELLS
US7745123B2 (en) 2004-07-23 2010-06-29 Ge Healthcare Uk Limited Cell cycle reporting cell line
CN101052646B (zh) * 2004-07-23 2015-10-21 通用电气医疗集团英国有限公司 细胞周期阶段标志物
JP5143552B2 (ja) 2004-07-23 2013-02-13 ジーイー・ヘルスケア・ユーケイ・リミテッド 細胞周期フェーズマーカー
JP5408839B2 (ja) * 2006-10-20 2014-02-05 オリンパス株式会社 細胞周期解析方法
EP2275567A1 (en) * 2009-07-15 2011-01-19 Rheinische Friedrich-Wilhelms-Universität Bonn Nucleic acid expression construct and its use as a cell proliferation marker
US10100305B2 (en) 2011-07-15 2018-10-16 Sarepta Therapeutics, Inc. Methods and compositions for manipulating translation of protein isoforms from alternative initiation of start sites

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288641A (en) * 1984-06-04 1994-02-22 Arch Development Corporation Herpes Simplex virus as a vector
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
FR2658204A1 (fr) * 1990-02-12 1991-08-16 Inst Nat Sante Rech Med Nouvelles compositions de cycline a humaine, sequence nucleotidique correspondante, et agents de detection ou de diagnostic de mutations hepatocellulaires induites par le virus hbv.
US6159691A (en) * 1996-05-15 2000-12-12 Prolifix Limited Assay for a putative regulator of cell cycle progression
US6124128A (en) * 1996-08-16 2000-09-26 The Regents Of The University Of California Long wavelength engineered fluorescent proteins
US6048693A (en) * 1996-10-16 2000-04-11 Bittech, Inc. Phenotypic assays of cyclin/cyclin-dependent kinase function
US6461813B2 (en) * 1998-09-21 2002-10-08 Rigel Pharmaceuticals, Inc. Multiparameter FACS assays to detect alterations in cell cycle regulation
DE19831420A1 (de) * 1998-07-14 2000-01-20 Hoechst Marion Roussel De Gmbh Expressionssysteme enthaltend chimäre Promotoren mit Bindungsstellen für rekombinante Transkriptionsfaktoren
US6764852B2 (en) * 1999-01-26 2004-07-20 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Internal ribosome entry site, vector containing same and uses thereof
GB0002261D0 (en) * 2000-02-02 2000-03-22 Amersham Pharm Biotech Uk Ltd Fluorescent detection method & reagent

Also Published As

Publication number Publication date
AU2002326036B2 (en) 2007-09-13
CA2461133A1 (en) 2003-04-17
JP4607454B2 (ja) 2011-01-05
US20070238123A1 (en) 2007-10-11
GB0123856D0 (en) 2001-11-28
WO2003031612A3 (en) 2003-10-30
ES2290326T3 (es) 2008-02-16
DE60221550D1 (de) 2007-09-13
ATE368753T1 (de) 2007-08-15
EP1432819A2 (en) 2004-06-30
JP2005504550A (ja) 2005-02-17
US7235401B2 (en) 2007-06-26
US20040248133A1 (en) 2004-12-09
IL160908A0 (en) 2004-08-31
EP1432819B1 (en) 2007-08-01
WO2003031612A2 (en) 2003-04-17
CA2461133C (en) 2009-02-10

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