DE60215627T2 - Impfstoff zur modulation zwischen t1 und t2 immunantworten - Google Patents
Impfstoff zur modulation zwischen t1 und t2 immunantworten Download PDFInfo
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- DE60215627T2 DE60215627T2 DE60215627T DE60215627T DE60215627T2 DE 60215627 T2 DE60215627 T2 DE 60215627T2 DE 60215627 T DE60215627 T DE 60215627T DE 60215627 T DE60215627 T DE 60215627T DE 60215627 T2 DE60215627 T2 DE 60215627T2
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6018—Lipids, e.g. in lipopeptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Dispersion Chemistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Biotechnology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27869801P | 2001-03-27 | 2001-03-27 | |
| US278698P | 2001-03-27 | ||
| PCT/IB2002/002188 WO2002076485A2 (en) | 2001-03-27 | 2002-03-27 | Vaccine for modulating between t1 and t2 immune responses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60215627D1 DE60215627D1 (de) | 2006-12-07 |
| DE60215627T2 true DE60215627T2 (de) | 2007-07-19 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60215627T Expired - Lifetime DE60215627T2 (de) | 2001-03-27 | 2002-03-27 | Impfstoff zur modulation zwischen t1 und t2 immunantworten |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8198400B2 (enExample) |
| EP (1) | EP1377275B1 (enExample) |
| JP (2) | JP2004533421A (enExample) |
| AT (1) | ATE343375T1 (enExample) |
| AU (1) | AU2002309141B2 (enExample) |
| CA (1) | CA2441809C (enExample) |
| DE (1) | DE60215627T2 (enExample) |
| ES (1) | ES2424131T3 (enExample) |
| WO (1) | WO2002076485A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8198400B2 (en) | 2001-03-27 | 2012-06-12 | Oncothyreon, Inc. | Vaccine for modulating between T1 and T2 immune responses |
| US20060069238A1 (en) * | 2002-04-15 | 2006-03-30 | Biomira, Inc. | Synthetic glyco-lipo-peptides as vaccines |
| CA2542327C (en) * | 2003-10-14 | 2014-08-12 | Biomira, Inc. | Combination therapy for cancer |
| TWI395591B (zh) * | 2004-04-01 | 2013-05-11 | Oncothyreon Inc | 黏液性糖蛋白（ｍｕｃ-１）疫苗 |
| ES2526344T3 (es) * | 2005-06-28 | 2015-01-09 | Oncothyreon Inc. | Método para el tratamiento de pacientes con una vacuna de glicoproteína mucinosa (MUC-1) |
| WO2010002478A2 (en) | 2008-07-03 | 2010-01-07 | University Of Georgia Research Foundation, Inc. | Glycopeptide and uses thereof |
| US8703180B1 (en) * | 2007-10-23 | 2014-04-22 | Abbott Cardiovascular Systems Inc. | Multiple growth factor compositions, methods of fabrication, and methods of treatment |
| DK2411815T3 (en) * | 2009-03-24 | 2015-11-30 | Transgene Sa | Biomarker MONITORING OF PATIENTS |
| RU2552292C2 (ru) | 2009-07-10 | 2015-06-10 | Трансжене Са | Биомаркер для отбора пациентов и связанные с ним способы |
| KR20140023903A (ko) | 2011-02-24 | 2014-02-27 | 온코타이레온, 인코포레이티드 | 항원보강제를 갖는 muc1 기초 당지질펩티드 백신 |
| WO2015104656A1 (en) | 2014-01-07 | 2015-07-16 | Babita Agrawal | Immunomodulatory compositions and methods of use thereof |
| EP4480544A3 (en) | 2015-08-25 | 2025-03-26 | Babita Agrawal | Immunomodulatory compositions andmethods of use thereof |
| US20190076460A1 (en) * | 2017-02-22 | 2019-03-14 | Enyu Ding | An mRNA cancer vaccine encoding human GM-CSF fused to multiple tandem epitopes |
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| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US5019383A (en) | 1981-01-09 | 1991-05-28 | New York Blood Center, Inc. | Fatty acid carriers for synthetic peptides |
| ZA831547B (en) | 1982-03-15 | 1984-10-31 | New York Blood Center Inc | Fatty acid carriers for synthetic vaccines |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US6090406A (en) * | 1984-04-12 | 2000-07-18 | The Liposome Company, Inc. | Potentiation of immune responses with liposomal adjuvants |
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| US5837249A (en) | 1985-04-19 | 1998-11-17 | The Wistar Institute | Method for generating an immunogenic T cell response protective against a virus |
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| IT1213029B (it) | 1986-01-30 | 1989-12-07 | Bracco Ind Chimica Spa | Chelati di ioni metallici paramagnetici. |
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| US4868155A (en) | 1987-10-05 | 1989-09-19 | Merck & Co., Inc. | Dipeptidyl 4-0-,6-0-acyl-2-amino-2-deoxy-D-glucose compositions and methods of use in AIDS-immunocompromised human hosts |
| US5993823A (en) | 1990-12-18 | 1999-11-30 | Institut Pasteur De Lille | Cytotoxic T lymphocyte-inducing lipopeptides and methods of use |
| FR2670787B1 (fr) | 1990-12-18 | 1995-06-23 | Pasteur Institut | Lipopeptides inducteurs des lymphocytes t cytotoxiques et utilisation comme vaccins. |
| US5871746A (en) | 1990-12-18 | 1999-02-16 | Institut National De La Sainte Et De La Recherche Medicale (Inserm) | Cytotoxic T lymphocyte-inducing lipopeptides and use as vaccines |
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| US5580563A (en) * | 1992-05-01 | 1996-12-03 | Tam; James P. | Multiple antigen peptide system having adjuvant properties, vaccines prepared therefrom and methods of use thereof |
| US5744144A (en) | 1993-07-30 | 1998-04-28 | University Of Pittsburgh University Patent Committee Policy And Procedures | Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof |
| WO1995027505A1 (en) | 1994-04-12 | 1995-10-19 | Biomira, Inc. | Cellular immune response-specific antigens and uses therefor |
| CA2189356A1 (en) | 1994-05-02 | 1995-11-09 | Ting Chi Wong | Process for preparation of glycosides of tumor-associated carbohydrate antigens |
| AU6260796A (en) * | 1995-06-07 | 1996-12-30 | National Jewish Center For Immunology And Respiratory Medicine | Isolated formylated bacterial peptides, nucleic acid molecul es and uses thereof |
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| JP2001510440A (ja) | 1996-03-20 | 2001-07-31 | スローン―ケタリング・インスティテュート・フォー・キャンサー・リサーチ | ムチン接合体ペプチドワクチン |
| CA2252055C (en) * | 1996-04-11 | 2007-01-16 | The University Of British Columbia | Fusogenic liposomes |
| US5910306A (en) * | 1996-11-14 | 1999-06-08 | The United States Of America As Represented By The Secretary Of The Army | Transdermal delivery system for antigen |
| WO1998050527A1 (en) * | 1997-05-08 | 1998-11-12 | Biomira Inc. | Method for generating activated t-cells and antigen-pulsed antigen-presenting cells |
| FR2774687B1 (fr) * | 1998-02-06 | 2002-03-22 | Inst Nat Sante Rech Med | Lipopeptides contenant un fragment de l'interferon gamma, et leur utilisation dans des compositions pharmaceutiques |
| FR2776926B1 (fr) * | 1998-04-07 | 2003-10-24 | Inst Nat Sante Rech Med | Lipopeptides inducteurs de cytotoxicite t lymphocytaire portant au moins un epitope t auxiliaire, et leurs utilisations pour la vaccination |
| US20020051813A1 (en) | 1999-01-15 | 2002-05-02 | Lawrence Boni | Lipomatrix preparation |
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| JP2003519096A (ja) | 1999-08-18 | 2003-06-17 | アルタレックス コーポレーション | Ｍｕｃ−１抗原に対する治療用抗体およびその使用方法 |
| JP2003510094A (ja) | 1999-09-08 | 2003-03-18 | トランジェーヌ、ソシエテ、アノニム | Ｍｕｃ−１由来のペプチド |
| WO2001036433A2 (en) | 1999-11-15 | 2001-05-25 | Biomira, Inc. | Synthetic lipid-a analogs and uses thereof |
| WO2001070265A2 (en) | 2000-03-24 | 2001-09-27 | Biomira, Inc. | Lipopeptide adjuvants |
| EP1182210A1 (en) | 2000-08-17 | 2002-02-27 | BASTERT, Gunter, Prof.Dr.med.Dr.h.c. | Epitopes of tumor-associated MUC1 antigen |
| EP1343476B1 (en) | 2000-12-01 | 2008-05-28 | Biomira Inc. | Preparation of large liposomes by infusion into peg |
| US8198400B2 (en) | 2001-03-27 | 2012-06-12 | Oncothyreon, Inc. | Vaccine for modulating between T1 and T2 immune responses |
| US20060069238A1 (en) | 2002-04-15 | 2006-03-30 | Biomira, Inc. | Synthetic glyco-lipo-peptides as vaccines |
| ATE457733T1 (de) | 2002-05-09 | 2010-03-15 | Oncothyreon Inc | Lipid-a- und andere kohlenhydrat-liganden-analoga |
| TWI395591B (zh) | 2004-04-01 | 2013-05-11 | Oncothyreon Inc | 黏液性糖蛋白（ｍｕｃ-１）疫苗 |
| ES2526344T3 (es) | 2005-06-28 | 2015-01-09 | Oncothyreon Inc. | Método para el tratamiento de pacientes con una vacuna de glicoproteína mucinosa (MUC-1) |
-
2002
- 2002-03-27 US US10/106,876 patent/US8198400B2/en not_active Expired - Fee Related
- 2002-03-27 ES ES06022033T patent/ES2424131T3/es not_active Expired - Lifetime
- 2002-03-27 CA CA2441809A patent/CA2441809C/en not_active Expired - Fee Related
- 2002-03-27 WO PCT/IB2002/002188 patent/WO2002076485A2/en not_active Ceased
- 2002-03-27 EP EP02735795A patent/EP1377275B1/en not_active Expired - Lifetime
- 2002-03-27 AT AT02735795T patent/ATE343375T1/de not_active IP Right Cessation
- 2002-03-27 JP JP2002574998A patent/JP2004533421A/ja not_active Withdrawn
- 2002-03-27 AU AU2002309141A patent/AU2002309141B2/en not_active Ceased
- 2002-03-27 DE DE60215627T patent/DE60215627T2/de not_active Expired - Lifetime
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2010
- 2010-11-15 JP JP2010255171A patent/JP5519477B2/ja not_active Expired - Fee Related
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2012
- 2012-05-02 US US13/462,314 patent/US8552145B2/en not_active Expired - Fee Related
- 2012-05-02 US US13/462,356 patent/US20120269885A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2441809A1 (en) | 2002-10-03 |
| CA2441809C (en) | 2014-07-22 |
| DE60215627D1 (de) | 2006-12-07 |
| WO2002076485A3 (en) | 2003-05-30 |
| US20120269884A1 (en) | 2012-10-25 |
| US20120269885A1 (en) | 2012-10-25 |
| JP2011105720A (ja) | 2011-06-02 |
| US8552145B2 (en) | 2013-10-08 |
| WO2002076485A2 (en) | 2002-10-03 |
| US8198400B2 (en) | 2012-06-12 |
| JP2004533421A (ja) | 2004-11-04 |
| ATE343375T1 (de) | 2006-11-15 |
| EP1377275A2 (en) | 2004-01-07 |
| ES2424131T3 (es) | 2013-09-27 |
| EP1377275B1 (en) | 2006-10-25 |
| US20030157160A1 (en) | 2003-08-21 |
| AU2002309141B2 (en) | 2007-08-09 |
| JP5519477B2 (ja) | 2014-06-11 |
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Owner name: ONCOTHYREON, INC., SEATTLE, WASH., US |