DE602007010638D1 - Verfahren zur herstellung von fexofenadin - Google Patents
Verfahren zur herstellung von fexofenadinInfo
- Publication number
- DE602007010638D1 DE602007010638D1 DE602007010638T DE602007010638T DE602007010638D1 DE 602007010638 D1 DE602007010638 D1 DE 602007010638D1 DE 602007010638 T DE602007010638 T DE 602007010638T DE 602007010638 T DE602007010638 T DE 602007010638T DE 602007010638 D1 DE602007010638 D1 DE 602007010638D1
- Authority
- DE
- Germany
- Prior art keywords
- fexofenadine
- carboxylate
- hydroxydiphenylmethyl
- oxobutyl
- piperidyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Compounds Of Iron (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT001492A ITMI20061492A1 (it) | 2006-07-27 | 2006-07-27 | Processo per la preparazione di fexofenadina. |
PCT/IT2007/000525 WO2008012858A1 (en) | 2006-07-27 | 2007-07-25 | Process for preparing fexofenadine |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007010638D1 true DE602007010638D1 (de) | 2010-12-30 |
Family
ID=38777957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007010638T Active DE602007010638D1 (de) | 2006-07-27 | 2007-07-25 | Verfahren zur herstellung von fexofenadin |
Country Status (10)
Country | Link |
---|---|
US (1) | US9403770B2 (de) |
EP (1) | EP2046743B1 (de) |
JP (1) | JP5196501B2 (de) |
KR (1) | KR101413877B1 (de) |
CN (1) | CN101522619B (de) |
AT (1) | ATE488502T1 (de) |
DE (1) | DE602007010638D1 (de) |
ES (1) | ES2356269T3 (de) |
IT (1) | ITMI20061492A1 (de) |
WO (1) | WO2008012858A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106699559B (zh) * | 2015-11-12 | 2021-04-06 | 浙江九洲药业股份有限公司 | 一种洛索洛芬钠的制备工艺 |
CN107782804B (zh) * | 2016-08-25 | 2020-11-13 | 人福普克药业(武汉)有限公司 | 检测盐酸非索非那定样品中有关物质的方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4254129A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
US4254130A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
US5136070A (en) * | 1991-12-23 | 1992-08-04 | Dow Corning Corporation | Sodium borohydride catalyzed disproportionation of cycloorganosilanes |
DK0635004T3 (da) * | 1992-04-10 | 2002-11-11 | Merrell Pharma Inc | 4-Diphenylmethylpiperidinderivater og fremgangsmåde til fremstilling deraf |
US20020007068A1 (en) * | 1999-07-16 | 2002-01-17 | D'ambra Thomas E. | Piperidine derivatives and process for their production |
KR100387347B1 (ko) * | 1993-06-24 | 2003-11-28 | 알바니 몰레큘라 리써치, 인크. | 피페리딘 유도체 및 그의 제조 방법 |
CN1168717C (zh) * | 1993-06-25 | 2004-09-29 | 默里尔药物公司 | 用于制备抗组胺哌啶衍生物的新中间体 |
US6153754A (en) * | 1995-12-21 | 2000-11-28 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
US6201124B1 (en) * | 1995-12-21 | 2001-03-13 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
US6673933B2 (en) * | 1998-07-02 | 2004-01-06 | Aventis Pharmaceutical Inc. | Antihistaminic piperidine derivatives and intermediates for the preparation thereof |
ITRM20010260A1 (it) * | 2001-05-17 | 2002-11-18 | Dinamite Dipharma S P A In For | Processo per la preparazione della fexofenadina o acido 4 1-idrossi-4-4- (idrossidifenilmetil)-1-piperidinil|-butil|-alfa,alfa-dimetilbenz |
US6743941B2 (en) * | 2001-06-15 | 2004-06-01 | Aventis Pharma Deutschland Gmbh | Process for the production of piperidine derivatives |
ITMI20041143A1 (it) * | 2004-06-08 | 2004-09-08 | Dipharma Spa | Polimorfi di fexofenadina e procedimento per la loro preparazione |
EP1685106A2 (de) * | 2004-09-28 | 2006-08-02 | Teva Pharmaceutical Industries, Inc. | Fexofendadin-kristallform und verfahren zu deren herstellung |
-
2006
- 2006-07-27 IT IT001492A patent/ITMI20061492A1/it unknown
-
2007
- 2007-07-25 ES ES07805737T patent/ES2356269T3/es active Active
- 2007-07-25 DE DE602007010638T patent/DE602007010638D1/de active Active
- 2007-07-25 KR KR1020097001409A patent/KR101413877B1/ko not_active IP Right Cessation
- 2007-07-25 AT AT07805737T patent/ATE488502T1/de not_active IP Right Cessation
- 2007-07-25 US US12/374,539 patent/US9403770B2/en not_active Expired - Fee Related
- 2007-07-25 JP JP2009521422A patent/JP5196501B2/ja not_active Expired - Fee Related
- 2007-07-25 WO PCT/IT2007/000525 patent/WO2008012858A1/en active Application Filing
- 2007-07-25 CN CN2007800276927A patent/CN101522619B/zh not_active Expired - Fee Related
- 2007-07-25 EP EP07805737A patent/EP2046743B1/de not_active Not-in-force
Also Published As
Publication number | Publication date |
---|---|
EP2046743B1 (de) | 2010-11-17 |
KR20090034905A (ko) | 2009-04-08 |
KR101413877B1 (ko) | 2014-06-30 |
CN101522619B (zh) | 2012-01-04 |
JP2009544691A (ja) | 2009-12-17 |
ATE488502T1 (de) | 2010-12-15 |
ITMI20061492A1 (it) | 2008-01-28 |
US9403770B2 (en) | 2016-08-02 |
US20110190504A1 (en) | 2011-08-04 |
JP5196501B2 (ja) | 2013-05-15 |
CN101522619A (zh) | 2009-09-02 |
WO2008012858A1 (en) | 2008-01-31 |
ES2356269T3 (es) | 2011-04-06 |
EP2046743A1 (de) | 2009-04-15 |
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