DE602006020074D1 - Enzyme zur reduzierung von immunologischem stress - Google Patents

Enzyme zur reduzierung von immunologischem stress

Info

Publication number
DE602006020074D1
DE602006020074D1 DE602006020074T DE602006020074T DE602006020074D1 DE 602006020074 D1 DE602006020074 D1 DE 602006020074D1 DE 602006020074 T DE602006020074 T DE 602006020074T DE 602006020074 T DE602006020074 T DE 602006020074T DE 602006020074 D1 DE602006020074 D1 DE 602006020074D1
Authority
DE
Germany
Prior art keywords
enzymes
immunological stress
reducing immunological
reducing
stress
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006020074T
Other languages
English (en)
Inventor
David M Anderson
Humg-Yu Hsiao
Lin Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Chemgen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemgen Corp filed Critical Chemgen Corp
Publication of DE602006020074D1 publication Critical patent/DE602006020074D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/244—Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C12N9/2488—Mannanases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C12N9/2488—Mannanases
    • C12N9/2494—Mannan endo-1,4-beta-mannosidase (3.2.1.78), i.e. endo-beta-mannanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01006—Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01014—Chitinase (3.2.1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01039—Glucan endo-1,3-beta-D-glucosidase (3.2.1.39)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01078—Mannan endo-1,4-beta-mannosidase (3.2.1.78), i.e. endo-beta-mannanase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Birds (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602006020074T 2005-12-15 2006-12-14 Enzyme zur reduzierung von immunologischem stress Active DE602006020074D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75033905P 2005-12-15 2005-12-15
PCT/US2006/047592 WO2007075343A2 (en) 2005-12-15 2006-12-14 Enzymes for reduced immunological stress

Publications (1)

Publication Number Publication Date
DE602006020074D1 true DE602006020074D1 (de) 2011-03-24

Family

ID=38218427

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006020074T Active DE602006020074D1 (de) 2005-12-15 2006-12-14 Enzyme zur reduzierung von immunologischem stress

Country Status (35)

Country Link
US (5) US7914782B2 (de)
EP (2) EP1973561B1 (de)
JP (1) JP5189989B2 (de)
KR (2) KR101399205B1 (de)
CN (3) CN105831428B (de)
AR (1) AR057247A1 (de)
AT (1) ATE497779T1 (de)
AU (1) AU2006329927B2 (de)
BR (1) BRPI0620155B1 (de)
CA (1) CA2633066C (de)
CL (1) CL2011000941A1 (de)
CR (1) CR10116A (de)
DE (1) DE602006020074D1 (de)
DK (1) DK1973561T3 (de)
EC (1) ECSP088578A (de)
ES (1) ES2361819T3 (de)
GT (1) GT200600512A (de)
HN (1) HN2008000906A (de)
HR (1) HRP20080319B1 (de)
IL (2) IL192088A (de)
IN (1) IN2008DE06112A (de)
MX (1) MX284326B (de)
MY (1) MY145870A (de)
NO (1) NO340818B1 (de)
NZ (1) NZ569186A (de)
PE (1) PE20070840A1 (de)
PL (1) PL1973561T3 (de)
PT (1) PT1973561E (de)
RU (1) RU2465005C2 (de)
SI (1) SI1973561T1 (de)
SV (1) SV2008002942A (de)
TW (2) TWI402039B (de)
UA (1) UA95266C2 (de)
WO (1) WO2007075343A2 (de)
ZA (1) ZA200805780B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1973561T1 (sl) 2005-12-15 2011-07-29 Chemgen Corp Encimi, ki zmanjĺ ujejo imunski stres
WO2013122799A1 (en) * 2012-02-16 2013-08-22 Eli Lilly And Company Methods and compositions for reducing the environmental impact of animal waste
US20160183561A1 (en) * 2013-07-26 2016-06-30 Novozymes A/S Polypeptides having a-L-Galactosidase Activity and Polynucleotides Encoding Same
DK3119901T3 (da) * 2014-03-21 2021-07-26 Dsm Ip Assets Bv Fremgangsmåde til behanlding af gærcellevægge med en laminaripentaose-producerende beta-1,3-glucanase
CN106771257A (zh) * 2017-01-24 2017-05-31 北京美正生物科技有限公司 一种检测血清淀粉样蛋白a的酶联免疫吸附试剂盒及其制备方法和用途
CN107156522A (zh) * 2017-06-23 2017-09-15 都匀市山郎科技养殖有限公司 一种鸡饲料

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58201949A (ja) * 1982-05-17 1983-11-25 Kyodo Shiryo Kk 家畜用配合飼料
US5372939A (en) * 1991-03-21 1994-12-13 The United States Of America As Represented By The United States Department Of Energy Combined enzyme mediated fermentation of cellulous and xylose to ethanol by Schizosaccharoyces pombe, cellulase, β-glucosidase, and xylose isomerase
JP2942384B2 (ja) * 1991-06-07 1999-08-30 株式会社ヤクルト本社 飼料効率改善添加剤
GB2261877A (en) * 1991-11-21 1993-06-02 Kyowa Hakko Kogyo Kk Animal feed additive comprising enzyme and amino acid
WO1995005455A1 (en) * 1993-08-13 1995-02-23 Rijksuniversiteit Te Groningen Pharmaceutical composition comprising phosphatase or a derivative thereof
US5861271A (en) * 1993-12-17 1999-01-19 Fowler; Timothy Cellulase enzymes and systems for their expressions
DK1142485T3 (da) * 1994-04-22 2008-06-02 Novozymes As Fremgangsmåde til forbedring af oplöseligheden af planteproteiner
GB9416841D0 (en) * 1994-08-19 1994-10-12 Finnfeeds Int Ltd An enzyme feed additive and animal feed including it
MY134684A (en) * 1995-05-15 2007-12-31 Gist Brocades Bv Application of phospholipases in animal feed
JP2001057852A (ja) * 1995-06-14 2001-03-06 Showa Denko Kk 耐熱酵素含有飼料用組成物
US5807694A (en) * 1995-09-07 1998-09-15 Economic Innovation And Technology Council, University Of Manitoba Detection of salmonella enteritidis and other pathogenic microorganisms and monoclonal antibody useful therefor
EP0862371B1 (de) * 1995-11-06 2002-05-08 Novozymes A/S Verwendung von Galactanase in Tierfutter
WO1997039114A1 (en) * 1996-04-12 1997-10-23 Novo Nordisk A/S AN ENZYME WITH β-1,3-GLUCANASE ACTIVITY
US6162473A (en) 1996-05-03 2000-12-19 Chemgen Corporation Hemicellulase use in feeds with low caloric content
CN1092495C (zh) 1996-05-03 2002-10-16 开姆根有限公司 半纤维素酶在低热焓饲料中的应用
US20020164751A1 (en) * 1996-06-19 2002-11-07 Short Jay M. Enzymes having thermostable phosphatase activity and methods of use thereof
GB9623539D0 (en) * 1996-11-12 1997-01-08 Biotal Ltd Enzymes and their use
GB2327345B (en) * 1997-07-18 1999-06-23 Finnfeeds Int Ltd Use of an enzyme for manufacturing an agent for controlling bacterial infection
US6022566A (en) * 1997-12-02 2000-02-08 Balchem Corporation Method for increasing the feed intake, feed efficiency, daily gain and/or carcass grade in ruminants
EP0976838A1 (de) * 1998-05-06 2000-02-02 Rhone-Poulenc Nutrition Animale Enzymgemisch
US6331426B1 (en) * 1999-02-11 2001-12-18 Novozymes A/S Bacterial galactanases and use thereof
US6213930B1 (en) * 1999-03-15 2001-04-10 Wisconsin Alumni Research Foundation Method of using anti-phospholipase A2 antibodies to enhance growth or improve feed efficiency
US6500658B1 (en) * 1999-08-17 2002-12-31 Novozymes, A/S Xyloglucanase from Malbranchea
UA78486C2 (uk) * 1999-12-10 2007-04-10 Хемджен Корпорейшн Композиція для перорального введення птахам та тваринам для лікування або зниження ризику інфекції травного тракту (варіанти), її застосування (варіанти) та спосіб лікування або зниження ризику інфекцій травного тракту (варіанти)
GB0010748D0 (en) 2000-05-05 2000-06-28 Brown Paul D Tricep exercise horse (fold up and portable)
US20020095135A1 (en) * 2000-06-19 2002-07-18 David Meeker Combination enzyme replacement, gene therapy and small molecule therapy for lysosomal storage diseases
GB2371013B (en) 2001-01-16 2004-06-09 Terry John Claydon Copying apparatus
KR20040101889A (ko) * 2001-01-17 2004-12-03 라모트 앳 텔-아비브 유니버시티 리미티드 식충성 식물 유래의 키티나제, 이를 암호화하는폴리뉴클레오타이드 서열 및 이의 분리방법 및 사용방법
DE10105306A1 (de) * 2001-02-02 2002-08-22 Nutrinova Gmbh Futtermittel für die Nutztieraufzucht enthaltend Sorbinsäure und Enzyme
DE10105347A1 (de) 2001-02-05 2002-08-22 Nutrinova Gmbh Sorbinsäurepräparat enthaltend Probiotika als Futtermittelzusatz in der Nutztieraufzucht
IE20011100A1 (en) * 2001-12-21 2003-07-09 Vsl Pharma Ltd Analytical Method for Detecting Alkaline Sphingomyelinase and Kit for Use in Such Method
EP1471799A2 (de) * 2002-01-25 2004-11-03 DSM IP Assets B.V. Hitzestabile enzympräparate
AU2003304239A1 (en) * 2002-11-13 2005-01-13 Yvonne J. Rosenberg A pretreatment or post exposure treatment for exposure to a toxic substance by pulmonary delivery (inhaler) of a bioscavenger
WO2004054609A1 (en) 2002-12-12 2004-07-01 Zoltan Laboratories Placental alkaline phosphatase to control diabetes
US20110142817A1 (en) * 2004-02-04 2011-06-16 Pharmaaware Sepsis B.V. Means and method for treating and/or preventing necrotizing enterocolitis
AU2005210581B2 (en) * 2004-02-04 2010-06-24 Am-Pharma B.V. Use of alkaline phosphatase for the detoxification of LPS present at mucosal barriers
PL1740204T3 (pl) * 2004-04-01 2018-08-31 Chiesi Farmaceutici S.P.A. Lecznicze zastosowanie alfa-mannozydazy
CN101208436B (zh) * 2005-03-25 2012-10-03 根特大学 类黄酮的酶促脱甲基化
CN1699576A (zh) * 2005-06-30 2005-11-23 江南大学 一种内切β－1,3葡聚糖酶基因及其克隆方法
EP1931332A4 (de) * 2005-09-12 2010-06-23 Zoltan Lab Llc Verbindungen und zusammensetzungen zur kontrolle von anomalem zellwachstum
SI1973561T1 (sl) * 2005-12-15 2011-07-29 Chemgen Corp Encimi, ki zmanjĺ ujejo imunski stres
WO2009106368A1 (en) * 2008-02-29 2009-09-03 Gelato Corporation N.V. Method for increasing the activity of the immune system of a mammal at risk of inflammatory diseases

Also Published As

Publication number Publication date
ES2361819T3 (es) 2011-06-22
IL192088A0 (en) 2009-02-11
AU2006329927B2 (en) 2011-09-29
US8778648B2 (en) 2014-07-15
PE20070840A1 (es) 2007-08-25
CL2011000941A1 (es) 2014-08-08
NZ569186A (en) 2011-09-30
CA2633066A1 (en) 2007-07-05
US20110171345A1 (en) 2011-07-14
US20110171344A1 (en) 2011-07-14
ECSP088578A (es) 2008-10-31
HRP20080319A2 (en) 2008-12-31
CR10116A (es) 2008-10-28
MX2008007735A (en) 2008-08-27
BRPI0620155B1 (pt) 2015-07-21
DK1973561T3 (da) 2011-05-23
SI1973561T1 (sl) 2011-07-29
CN101374544B (zh) 2016-05-18
US20110177195A1 (en) 2011-07-21
SV2008002942A (es) 2008-12-03
CN105831428B (zh) 2020-12-01
MY145870A (en) 2012-05-15
ZA200805780B (en) 2009-03-25
MX284326B (en) 2011-03-01
BRPI0620155A2 (pt) 2011-11-01
EP2263685A3 (de) 2011-04-06
UA95266C2 (uk) 2011-07-25
EP2263685A2 (de) 2010-12-22
EP1973561B1 (de) 2011-02-09
PL1973561T3 (pl) 2011-08-31
RU2008128583A (ru) 2010-01-20
US7914782B2 (en) 2011-03-29
CN105831428A (zh) 2016-08-10
NO20083035L (no) 2008-09-11
TWI619506B (zh) 2018-04-01
KR101399205B1 (ko) 2014-05-27
HN2008000906A (es) 2011-07-12
JP5189989B2 (ja) 2013-04-24
TWI402039B (zh) 2013-07-21
KR20080081972A (ko) 2008-09-10
CN101374544A (zh) 2009-02-25
JP2009519712A (ja) 2009-05-21
KR101454032B1 (ko) 2014-10-27
NO340818B1 (no) 2017-06-26
CA2633066C (en) 2015-01-20
IL192088A (en) 2013-07-31
IL227318A (en) 2016-11-30
WO2007075343A3 (en) 2007-10-04
US20170156371A1 (en) 2017-06-08
EP1973561A2 (de) 2008-10-01
KR20130082514A (ko) 2013-07-19
HRP20080319B1 (hr) 2015-11-20
AU2006329927A1 (en) 2007-07-05
WO2007075343A2 (en) 2007-07-05
GT200600512A (es) 2007-06-28
TW201336425A (zh) 2013-09-16
US20070141041A1 (en) 2007-06-21
ATE497779T1 (de) 2011-02-15
RU2465005C2 (ru) 2012-10-27
TW200731932A (en) 2007-09-01
PT1973561E (pt) 2011-05-12
AR057247A1 (es) 2007-11-21
IN2008DE06112A (de) 2008-09-26
CN102293323A (zh) 2011-12-28

Similar Documents

Publication Publication Date Title
DK1737974T3 (da) Fremgangsmåder til identifikation af proteiner med stivelsesphosphorylerende enzymatisk aktivitet
DK1848718T3 (da) E1 aktiveringsenzymhæmmere
EP1969123A4 (de) Neue enzyme
DE602005022454D1 (de) Enzymatische nachweistechniken
DK1926393T3 (da) Phytaseholdigt enzymgranulat
IL190988A0 (en) Novel highly functional enzyme having modified substrate-specificity
EP1859035A4 (de) Immobilisierte enzyme
ATE497779T1 (de) Enzyme zur reduzierung von immunologischem stress
EP1889919A4 (de) Verfahren zur enzymanalyse
FI20055692A0 (fi) Uusia entsyymejä
DE502005000305D1 (de) Photobioreaktor
EP1915443A4 (de) Immobilisierte enzyme und verwendungsverfahren dafür
DK1907567T3 (da) Forbedrede ekstraktionsfremgangsmåder og assay til fødevareenzymer
DK1657303T3 (da) Fremgangsmåde til at fremstille et immobiliseret enzym
DE602006018034D1 (de) Enzymherstellungsverfahren
DE602005014475D1 (de) Nukleinsäure/enzym-komplex
BRPI0818162A2 (pt) Métodos enzimáticos e enzimas
FI20065035A0 (fi) Olennaisesti puhdas entsyymi
DK1937808T3 (da) Forbedring af enzymproduktion
DK1910527T3 (da) Maltose-1-phosphat producerende enzym
GB0506074D0 (en) Improved enzyme assay
FIU20100337U0 (fi) Entsyymirakeet
FIU20100336U0 (fi) Entsyymirakeet
GB0526169D0 (en) Enzyme inhibitors
GB0606627D0 (en) Improved enzyme assay

Legal Events

Date Code Title Description
R082 Change of representative

Ref document number: 1973561

Country of ref document: EP

Representative=s name: BOEHMERT & BOEHMERT, DE

R081 Change of applicant/patentee

Ref document number: 1973561

Country of ref document: EP

Owner name: ELI LILLY AND COMPANY, US

Free format text: FORMER OWNER: CHEMGEN CORP., GAITHERSBURG, US

Effective date: 20120829

R082 Change of representative

Ref document number: 1973561

Country of ref document: EP

Representative=s name: BOEHMERT & BOEHMERT, DE

Effective date: 20120829