CR10116A - Enzimas para estres inmunólogico reducido - Google Patents

Enzimas para estres inmunólogico reducido

Info

Publication number
CR10116A
CR10116A CR10116A CR10116A CR10116A CR 10116 A CR10116 A CR 10116A CR 10116 A CR10116 A CR 10116A CR 10116 A CR10116 A CR 10116A CR 10116 A CR10116 A CR 10116A
Authority
CR
Costa Rica
Prior art keywords
animal
enzymes
immunological stress
reduced immunological
level
Prior art date
Application number
CR10116A
Other languages
English (en)
Inventor
M Anderson David
Hsiao Humg-Yu
Liu Lin
Original Assignee
Lilly Co Eli
Memory Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Memory Pharm Corp filed Critical Lilly Co Eli
Publication of CR10116A publication Critical patent/CR10116A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/244—Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C12N9/2488—Mannanases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C12N9/2488—Mannanases
    • C12N9/2494—Mannan endo-1,4-beta-mannosidase (3.2.1.78), i.e. endo-beta-mannanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01006—Endo-1,3(4)-beta-glucanase (3.2.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01014—Chitinase (3.2.1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01039—Glucan endo-1,3-beta-D-glucosidase (3.2.1.39)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01078—Mannan endo-1,4-beta-mannosidase (3.2.1.78), i.e. endo-beta-mannanase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Birds (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere composiciones adecuadas para administración oral a un mamífero que comprende, al menos una enzima que reduce el estrés inmune en una cantidad efectiva para reducir el nivel de proteína de fase aguda positiva en un animal, incrementar el nivel de proteína de fase aguda negativa en un animal, y/o mejorar el desempeño de crecimiento del animal, como son métodos para usar tales composiciones.
CR10116A 2005-12-15 2008-06-26 Enzimas para estres inmunólogico reducido CR10116A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75033905P 2005-12-15 2005-12-15

Publications (1)

Publication Number Publication Date
CR10116A true CR10116A (es) 2008-10-28

Family

ID=38218427

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10116A CR10116A (es) 2005-12-15 2008-06-26 Enzimas para estres inmunólogico reducido

Country Status (35)

Country Link
US (5) US7914782B2 (es)
EP (2) EP2263685A3 (es)
JP (1) JP5189989B2 (es)
KR (2) KR101454032B1 (es)
CN (3) CN105831428B (es)
AR (1) AR057247A1 (es)
AT (1) ATE497779T1 (es)
AU (1) AU2006329927B2 (es)
BR (1) BRPI0620155B1 (es)
CA (1) CA2633066C (es)
CL (1) CL2011000941A1 (es)
CR (1) CR10116A (es)
DE (1) DE602006020074D1 (es)
DK (1) DK1973561T3 (es)
EC (1) ECSP088578A (es)
ES (1) ES2361819T3 (es)
GT (1) GT200600512A (es)
HN (1) HN2008000906A (es)
HR (1) HRP20080319B1 (es)
IL (2) IL192088A (es)
IN (1) IN2008DE06112A (es)
MX (1) MX284326B (es)
MY (1) MY145870A (es)
NO (1) NO340818B1 (es)
NZ (1) NZ569186A (es)
PE (1) PE20070840A1 (es)
PL (1) PL1973561T3 (es)
PT (1) PT1973561E (es)
RU (1) RU2465005C2 (es)
SI (1) SI1973561T1 (es)
SV (1) SV2008002942A (es)
TW (2) TWI619506B (es)
UA (1) UA95266C2 (es)
WO (1) WO2007075343A2 (es)
ZA (1) ZA200805780B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0620155B1 (pt) * 2005-12-15 2015-07-21 Lilly Co Eli Composição adequada para administração oral a um animal compreendendo uma enzima redutora de estresse imunológico em um veículo aceitável por via oral
PL2814331T3 (pl) * 2012-02-16 2019-04-30 Elanco Inc Sposoby i kompozycje do zmniejszenia wpływu odpadów zwierzęcych na środowisko
EP3030093B1 (en) * 2013-07-26 2017-09-06 Novozymes A/S POLYPEPTIDES HAVING alpha-L-GALACTOSIDASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
CN106103727A (zh) * 2014-03-21 2016-11-09 帝斯曼知识产权资产管理有限公司 用产生昆布五糖的β‑1,3‑葡聚糖酶处理酵母细胞壁的方法
CN106771257A (zh) * 2017-01-24 2017-05-31 北京美正生物科技有限公司 一种检测血清淀粉样蛋白a的酶联免疫吸附试剂盒及其制备方法和用途
CN107156522A (zh) * 2017-06-23 2017-09-15 都匀市山郎科技养殖有限公司 一种鸡饲料

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58201949A (ja) * 1982-05-17 1983-11-25 Kyodo Shiryo Kk 家畜用配合飼料
US5372939A (en) * 1991-03-21 1994-12-13 The United States Of America As Represented By The United States Department Of Energy Combined enzyme mediated fermentation of cellulous and xylose to ethanol by Schizosaccharoyces pombe, cellulase, β-glucosidase, and xylose isomerase
JP2942384B2 (ja) * 1991-06-07 1999-08-30 株式会社ヤクルト本社 飼料効率改善添加剤
GB2261877A (en) 1991-11-21 1993-06-02 Kyowa Hakko Kogyo Kk Animal feed additive comprising enzyme and amino acid
WO1995005455A1 (en) 1993-08-13 1995-02-23 Rijksuniversiteit Te Groningen Pharmaceutical composition comprising phosphatase or a derivative thereof
US5861271A (en) * 1993-12-17 1999-01-19 Fowler; Timothy Cellulase enzymes and systems for their expressions
WO1995028850A1 (en) 1994-04-22 1995-11-02 Novo Nordisk A/S A method for improving the solubility of vegetable proteins
GB9416841D0 (en) * 1994-08-19 1994-10-12 Finnfeeds Int Ltd An enzyme feed additive and animal feed including it
NL1003096C2 (nl) * 1995-05-15 1996-11-19 Gist Brocades Bv Application of phospholipases in animal feed.
JP2001057852A (ja) * 1995-06-14 2001-03-06 Showa Denko Kk 耐熱酵素含有飼料用組成物
US5807694A (en) * 1995-09-07 1998-09-15 Economic Innovation And Technology Council, University Of Manitoba Detection of salmonella enteritidis and other pathogenic microorganisms and monoclonal antibody useful therefor
BR9611347A (pt) * 1995-11-06 1999-03-09 Novo Nordisk As Aditivo de ração para animal e processos para melhorar a retirada de energia de uma dieta para animal e para pré-tratar ração para animal
WO1997039114A1 (en) * 1996-04-12 1997-10-23 Novo Nordisk A/S AN ENZYME WITH β-1,3-GLUCANASE ACTIVITY
US6162473A (en) * 1996-05-03 2000-12-19 Chemgen Corporation Hemicellulase use in feeds with low caloric content
CN1092495C (zh) 1996-05-03 2002-10-16 开姆根有限公司 半纤维素酶在低热焓饲料中的应用
US20020164751A1 (en) * 1996-06-19 2002-11-07 Short Jay M. Enzymes having thermostable phosphatase activity and methods of use thereof
GB9623539D0 (en) * 1996-11-12 1997-01-08 Biotal Ltd Enzymes and their use
GB2327345B (en) 1997-07-18 1999-06-23 Finnfeeds Int Ltd Use of an enzyme for manufacturing an agent for controlling bacterial infection
US6022566A (en) * 1997-12-02 2000-02-08 Balchem Corporation Method for increasing the feed intake, feed efficiency, daily gain and/or carcass grade in ruminants
EP0976838A1 (en) * 1998-05-06 2000-02-02 Rhone-Poulenc Nutrition Animale Enzymes mixture
US6331426B1 (en) * 1999-02-11 2001-12-18 Novozymes A/S Bacterial galactanases and use thereof
US6213930B1 (en) * 1999-03-15 2001-04-10 Wisconsin Alumni Research Foundation Method of using anti-phospholipase A2 antibodies to enhance growth or improve feed efficiency
US6500658B1 (en) * 1999-08-17 2002-12-31 Novozymes, A/S Xyloglucanase from Malbranchea
UA78486C2 (uk) * 1999-12-10 2007-04-10 Хемджен Корпорейшн Композиція для перорального введення птахам та тваринам для лікування або зниження ризику інфекції травного тракту (варіанти), її застосування (варіанти) та спосіб лікування або зниження ризику інфекцій травного тракту (варіанти)
GB0010748D0 (en) 2000-05-05 2000-06-28 Brown Paul D Tricep exercise horse (fold up and portable)
US20020095135A1 (en) * 2000-06-19 2002-07-18 David Meeker Combination enzyme replacement, gene therapy and small molecule therapy for lysosomal storage diseases
GB2371013B (en) 2001-01-16 2004-06-09 Terry John Claydon Copying apparatus
WO2002057408A2 (en) * 2001-01-17 2002-07-25 Ramot At Tel Aviv University Ltd. Chitinases, derived from carnivorous plants polynucleotide sequences encoding thereof, and methods of isolating and using same
DE10105306A1 (de) * 2001-02-02 2002-08-22 Nutrinova Gmbh Futtermittel für die Nutztieraufzucht enthaltend Sorbinsäure und Enzyme
DE10105347A1 (de) * 2001-02-05 2002-08-22 Nutrinova Gmbh Sorbinsäurepräparat enthaltend Probiotika als Futtermittelzusatz in der Nutztieraufzucht
IE20011100A1 (en) * 2001-12-21 2003-07-09 Vsl Pharma Ltd Analytical Method for Detecting Alkaline Sphingomyelinase and Kit for Use in Such Method
AU2003203142A1 (en) * 2002-01-25 2003-09-02 Dsm Ip Assets B.V. Thermostable enzyme compositions
WO2005000195A2 (en) * 2002-11-13 2005-01-06 Rosenberg Yvonne J A pretreatment or post exposure treatment for exposure to a toxic substance by pulmonary delivery (inhaler) of a bioscavenger
AU2003298036A1 (en) 2002-12-12 2004-07-09 Zoltan Laboratories Placental alkaline phosphatase to control diabetes
CA2847517A1 (en) * 2004-02-04 2005-08-18 Pharmaaware Sepsis B.V. Use of alkaline phosphatase for the detoxification of lps present at mucosal barriers
US20110142817A1 (en) * 2004-02-04 2011-06-16 Pharmaaware Sepsis B.V. Means and method for treating and/or preventing necrotizing enterocolitis
DK1740204T3 (en) * 2004-04-01 2018-05-22 Chiesi Farm Spa MEDICAL USE OF ALFA MANNOSIDASE
CA2602707C (en) * 2005-03-25 2013-12-31 Universiteit Gent Enzymatic demethylation of flavonoids
CN1699576A (zh) * 2005-06-30 2005-11-23 江南大学 一种内切β－1,3葡聚糖酶基因及其克隆方法
WO2007032818A2 (en) 2005-09-12 2007-03-22 Zoltan Laboratories Llc Compounds and compositions to control abnormal cell growth
BRPI0620155B1 (pt) 2005-12-15 2015-07-21 Lilly Co Eli Composição adequada para administração oral a um animal compreendendo uma enzima redutora de estresse imunológico em um veículo aceitável por via oral
US8784805B2 (en) * 2008-02-29 2014-07-22 Alloksys Life Sciences B.V. Method for increasing the activity of the immune system of a mammal at risk of inflammatory diseases

Also Published As

Publication number Publication date
RU2465005C2 (ru) 2012-10-27
BRPI0620155A2 (pt) 2011-11-01
CN101374544A (zh) 2009-02-25
CN101374544B (zh) 2016-05-18
EP2263685A2 (en) 2010-12-22
IL227318A (en) 2016-11-30
EP1973561A2 (en) 2008-10-01
AU2006329927A1 (en) 2007-07-05
MX284326B (en) 2011-03-01
DE602006020074D1 (de) 2011-03-24
CN102293323A (zh) 2011-12-28
GT200600512A (es) 2007-06-28
KR101454032B1 (ko) 2014-10-27
KR20130082514A (ko) 2013-07-19
HRP20080319B1 (hr) 2015-11-20
HRP20080319A2 (en) 2008-12-31
PE20070840A1 (es) 2007-08-25
US20110177195A1 (en) 2011-07-21
WO2007075343A3 (en) 2007-10-04
JP5189989B2 (ja) 2013-04-24
EP2263685A3 (en) 2011-04-06
HN2008000906A (es) 2011-07-12
ES2361819T3 (es) 2011-06-22
IL192088A (en) 2013-07-31
NZ569186A (en) 2011-09-30
DK1973561T3 (da) 2011-05-23
EP1973561B1 (en) 2011-02-09
TW201336425A (zh) 2013-09-16
TW200731932A (en) 2007-09-01
US8778648B2 (en) 2014-07-15
KR101399205B1 (ko) 2014-05-27
US20110171345A1 (en) 2011-07-14
CN105831428A (zh) 2016-08-10
ECSP088578A (es) 2008-10-31
WO2007075343A2 (en) 2007-07-05
PT1973561E (pt) 2011-05-12
RU2008128583A (ru) 2010-01-20
CA2633066A1 (en) 2007-07-05
MY145870A (en) 2012-05-15
BRPI0620155B1 (pt) 2015-07-21
NO20083035L (no) 2008-09-11
AU2006329927B2 (en) 2011-09-29
CN105831428B (zh) 2020-12-01
ZA200805780B (en) 2009-03-25
UA95266C2 (uk) 2011-07-25
PL1973561T3 (pl) 2011-08-31
TWI619506B (zh) 2018-04-01
KR20080081972A (ko) 2008-09-10
US20070141041A1 (en) 2007-06-21
IL192088A0 (en) 2009-02-11
JP2009519712A (ja) 2009-05-21
AR057247A1 (es) 2007-11-21
ATE497779T1 (de) 2011-02-15
TWI402039B (zh) 2013-07-21
US20170156371A1 (en) 2017-06-08
SV2008002942A (es) 2008-12-03
MX2008007735A (en) 2008-08-27
SI1973561T1 (sl) 2011-07-29
US7914782B2 (en) 2011-03-29
NO340818B1 (no) 2017-06-26
IN2008DE06112A (es) 2008-09-26
US20110171344A1 (en) 2011-07-14
CL2011000941A1 (es) 2014-08-08
CA2633066C (en) 2015-01-20

Similar Documents

Publication Publication Date Title
CR10116A (es) Enzimas para estres inmunólogico reducido
CY1118601T1 (el) Αλκυλαμινο-υποκατεστημενες δικυανοπυριδινες και προφαρμακα τυπου εστερα αμινοξεος αυτων
UY31789A1 (es) Composiciones de insulina de super rápida actuación
BR112014014834A2 (pt) composições para cuidado oral
ES2570382T3 (es) Composiciones y métodos para la producción de azúcares fermentables
CL2012003656A1 (es) Uso de una composicion que comprende una enzima de reemplazo para la enzima lisosomal a una concentracion mayor a 5 mg/ml para tratar sintomas somaticos de la deficiencia de la enzima subyacente.
ES2723050T3 (es) Variantes de fitasa termoestables
AR087745A1 (es) Composiciones y metodos que comprenden una variante de enzima lipolitica
EA201890942A1 (ru) Мультивалентные вакцины с синтетическими наноносителями
MX2013001527A (es) Nuevas vacunas adyuvantes en base a adyuvantes de orientacion para anticuerpos directamente hacia celulas presentadoras de antigenos.
AR070498A1 (es) Composicion detergente que comprende lipasa
AR118760A2 (es) Coaglomerados de manitol y de almidón granular comprimibles y de libre fluidez
NI201200174A (es) Derivados de carbamato de hexafluoroisopropilo, su preparación y su aplicación en terapéutica.
AR076941A1 (es) Cepa de bacillus para una mayor produccion de proteina
SG10201405377XA (en) Compositions and methods for antibodies targeting complement protein c5
PE20140190A1 (es) Moduladores de proteinas notum y metodos de uso
AR084377A1 (es) Metodos y composiciones relacionados con enzimas de alcohol graso biosintetico
AR054525A1 (es) Composiciones y metodos para eltratamiento de sintomas relacionados con el ciclo
SG148171A1 (en) Methods of proliferating stem cells
EA201290199A1 (ru) Способы и композиции для получения сквалена с применением дрожжей
EA201391489A1 (ru) Композиции со сниженной вязкостью
NI200800176A (es) Uso de derivados de sulfamidas heterocíclicas benzo-fusionadas para el tratamiento de la depresión
CR8638A (es) Vacuna agalactiae estreptococos
RU2013134126A (ru) Способ снижения уровня с-концевого телопептида коллагена 2 типа
EA200800206A1 (ru) Комбинированное применение метконазола и эпоксиконазола для уменьшения или предотвращения заражения зерновых культур микотоксинами