DE602006018532D1 - Stationäre phase und säule unter verwendung von cucurbiturilgebundenem kieselgel, und verfahren zur abtrennung von taxol unter verwendung der säule - Google Patents
Stationäre phase und säule unter verwendung von cucurbiturilgebundenem kieselgel, und verfahren zur abtrennung von taxol unter verwendung der säuleInfo
- Publication number
- DE602006018532D1 DE602006018532D1 DE602006018532T DE602006018532T DE602006018532D1 DE 602006018532 D1 DE602006018532 D1 DE 602006018532D1 DE 602006018532 T DE602006018532 T DE 602006018532T DE 602006018532 T DE602006018532 T DE 602006018532T DE 602006018532 D1 DE602006018532 D1 DE 602006018532D1
- Authority
- DE
- Germany
- Prior art keywords
- taxane
- column
- pillar
- cucurbituril
- stationary phase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/KR2006/001096 WO2007111390A1 (en) | 2006-03-24 | 2006-03-24 | Stationary phase and column using cucurbituril bonded silica gel, and separation method of taxol using the column |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006018532D1 true DE602006018532D1 (de) | 2011-01-05 |
Family
ID=38541302
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006018532T Active DE602006018532D1 (de) | 2006-03-24 | 2006-03-24 | Stationäre phase und säule unter verwendung von cucurbiturilgebundenem kieselgel, und verfahren zur abtrennung von taxol unter verwendung der säule |
Country Status (7)
Country | Link |
---|---|
US (1) | US8002987B2 (de) |
EP (1) | EP1999122B1 (de) |
JP (1) | JP4651717B2 (de) |
KR (1) | KR100948143B1 (de) |
AT (1) | ATE489375T1 (de) |
DE (1) | DE602006018532D1 (de) |
WO (1) | WO2007111390A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9525092B2 (en) | 2010-11-05 | 2016-12-20 | Pacific Light Technologies Corp. | Solar module employing quantum luminescent lateral transfer concentrator |
US20130112942A1 (en) | 2011-11-09 | 2013-05-09 | Juanita Kurtin | Composite having semiconductor structures embedded in a matrix |
US9159872B2 (en) | 2011-11-09 | 2015-10-13 | Pacific Light Technologies Corp. | Semiconductor structure having nanocrystalline core and nanocrystalline shell |
US9425365B2 (en) | 2012-08-20 | 2016-08-23 | Pacific Light Technologies Corp. | Lighting device having highly luminescent quantum dots |
US8889457B2 (en) | 2012-12-13 | 2014-11-18 | Pacific Light Technologies Corp. | Composition having dispersion of nano-particles therein and methods of fabricating same |
KR102305379B1 (ko) * | 2013-11-25 | 2021-09-24 | 시코쿠가세이고교가부시키가이샤 | 작용기를 갖는 글리콜우릴류와 그의 이용 |
CN103920477B (zh) * | 2014-04-29 | 2016-03-30 | 河南中医学院 | 一种葫芦[6]脲键合硅胶固定相、制备方法及应用 |
CN105067744B (zh) * | 2015-07-31 | 2017-04-26 | 中国检验检疫科学研究院 | 一种采用葫芦脲固相萃取测定玩具中塑化剂迁移量的方法 |
CN108383197A (zh) * | 2018-04-09 | 2018-08-10 | 山东冬瑞高新技术开发有限公司 | 一种绿色印染废水处理剂及其制备方法 |
CN110078756A (zh) * | 2018-10-27 | 2019-08-02 | 西北大学 | 一种葫芦脲[6]修饰的硅胶载体及其制备方法和在高压液相色谱中的应用 |
CN111896670B (zh) * | 2020-07-24 | 2022-05-17 | 杭州师范大学 | 一种郁金的微提取方法 |
CN112375049B (zh) * | 2020-10-16 | 2023-03-07 | 广西民族大学 | 一种利用松香基键合硅胶固定相分离紫杉醇的方法 |
JP7289994B2 (ja) * | 2021-03-17 | 2023-06-12 | 株式会社ニッスイ | 精製の方法および精製された製品 |
CN113917060A (zh) * | 2021-10-08 | 2022-01-11 | 苏州圣苏新药开发有限公司 | 一种人血浆中紫杉醇的定量分析方法 |
CN115626930B (zh) * | 2022-10-20 | 2024-04-09 | 贵州大学 | 一种七元瓜环-三聚茚衍生物的合成方法及应用 |
CN115651098B (zh) * | 2022-11-15 | 2023-07-25 | 吉林大学 | 一种葫芦脲[7]/二硫代氨基甲酸酯超分子结合的raft链转移试剂及其制备方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4539399A (en) | 1984-07-27 | 1985-09-03 | Advanced Separation Technologies Inc. | Bonded phase material for chromatographic separations |
US5475120A (en) | 1990-11-02 | 1995-12-12 | University Of Florida | Method for the isolation and purification of taxol and its natural analogues |
AU1888792A (en) * | 1991-04-19 | 1992-11-17 | University Of Mississippi, The | Methods and compositions for isolating taxanes |
US5279949A (en) * | 1992-12-07 | 1994-01-18 | Board Of Trustees Operating Michigan State University | Process for the isolation and purification of taxol and taxanes from Taxus spp |
CA2126698A1 (en) * | 1992-12-07 | 1994-06-23 | Muraleedharan G. Nair | Process for the isolation and purification of taxol and taxanes from taxus spp. |
KR100390808B1 (ko) | 1998-11-19 | 2003-11-15 | 주식회사 대우일렉트로닉스 | 안정화된 포커스 오케이신호 발생회로 |
US5969165A (en) * | 1999-01-07 | 1999-10-19 | 508037 (Nb) Inc. | Isolation and purification of paclitaxel and other related taxanes by industrial preparative low pressure chromatography on a polymeric resin column |
JP3425900B2 (ja) | 1999-07-26 | 2003-07-14 | エヌイーシーマイクロシステム株式会社 | スイッチングレギュレータ |
DE60007257T2 (de) * | 1999-10-21 | 2004-09-16 | Pohang University Of Science And Technology Foundation, Pohang | Verfahren zur Herstellung von Cucurbituril Derivaten |
SE9904367D0 (sv) | 1999-12-02 | 1999-12-02 | Hoeganaes Ab | Lubricant combination and process for the preparation thereof |
US6706208B2 (en) | 1999-12-22 | 2004-03-16 | Nippon Shokubai Co., Ltd. | Stabilized hydroxyalkyl (meth)acrylate |
EP1335910A1 (de) * | 2000-11-13 | 2003-08-20 | Lahu Saiji | Isolierung von taxane |
KR100400085B1 (ko) * | 2001-07-04 | 2003-09-29 | 학교법인 포항공과대학교 | 수용성 및 지용성 쿠커비투릴 유도체, 그 제조방법, 그분리방법 및 용도 |
KR100499275B1 (ko) * | 2002-01-03 | 2005-07-01 | 학교법인 포항공과대학교 | 하이드록시쿠커비투릴 및 그 유도체, 그 제조방법 및이들의 용도 |
KR100528959B1 (ko) * | 2003-02-11 | 2005-11-16 | 학교법인 포항공과대학교 | 쿠커비투릴이 결합된 실리카 겔 |
US6956123B2 (en) * | 2003-03-17 | 2005-10-18 | Natural Pharmaccuticals, Inc. | Purification of taxanes and taxane mixtures using polyethyleneimine-bonded resins |
US7745620B2 (en) * | 2004-03-13 | 2010-06-29 | Postech Foundation | Disubstituted cucurbiturils and preparing method thereof |
US20060074254A1 (en) * | 2004-09-30 | 2006-04-06 | Zisheng Zhang | Process for extracting taxanes |
-
2006
- 2006-03-24 AT AT06732696T patent/ATE489375T1/de not_active IP Right Cessation
- 2006-03-24 JP JP2008541062A patent/JP4651717B2/ja not_active Expired - Fee Related
- 2006-03-24 DE DE602006018532T patent/DE602006018532D1/de active Active
- 2006-03-24 KR KR1020087002688A patent/KR100948143B1/ko not_active IP Right Cessation
- 2006-03-24 US US12/092,663 patent/US8002987B2/en not_active Expired - Fee Related
- 2006-03-24 WO PCT/KR2006/001096 patent/WO2007111390A1/en active Application Filing
- 2006-03-24 EP EP06732696A patent/EP1999122B1/de not_active Not-in-force
Also Published As
Publication number | Publication date |
---|---|
EP1999122A1 (de) | 2008-12-10 |
ATE489375T1 (de) | 2010-12-15 |
US20080290028A1 (en) | 2008-11-27 |
JP2009516194A (ja) | 2009-04-16 |
US8002987B2 (en) | 2011-08-23 |
EP1999122A4 (de) | 2010-02-24 |
WO2007111390A1 (en) | 2007-10-04 |
KR20080075832A (ko) | 2008-08-19 |
EP1999122B1 (de) | 2010-11-24 |
KR100948143B1 (ko) | 2010-03-18 |
JP4651717B2 (ja) | 2011-03-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE602006018532D1 (de) | Stationäre phase und säule unter verwendung von cucurbiturilgebundenem kieselgel, und verfahren zur abtrennung von taxol unter verwendung der säule | |
WO2015134317A8 (en) | Chromatographic materials for the separation of unsaturated molecules | |
DE502006006854D1 (de) | Substituierte benzo (d) isoaxol-3-yl-amin-verbindungen als analgetika | |
Altieri et al. | Regio and diastereoselective synthesis of functionalized 2, 3-dihydrofuro [3, 2-c] coumarins via a one-pot three-component reaction | |
CL2007003261A1 (es) | Compuestos derivados de 1,4-benzotiepina-1,1-dioxido; composicion farmaceutica; y su uso para el tratamiento de trastornos del metabolismo de lipidos, hiperlipidemia, resistencia a la insulina, diabetes y trastornos del snc, tales como esquizofrenia, | |
FI20115723A0 (fi) | Menetelmä ja laite biologista alkuperää olevan materiaalin puhdistamiseksi | |
IN2012DN05187A (de) | ||
MX2009005012A (es) | Una forma pura de rapamicina y procedimiento para la recuperacion y purificacion de la misma. | |
EA201000646A1 (ru) | Способ получения биопрепарата (варианты) | |
NZ586187A (en) | Processes for the synthesis of sinomenine derivatives and their intermediate | |
Lu et al. | Synthesis and cytotoxicity of a novel series of saframycin-ecteinascidin analogs containing tetrahydro-β-carboline moieties | |
EA200900353A1 (ru) | СПОСОБ ПОЛУЧЕНИЯ ГИДРОХЛОРИДА 1(10)β-ЭПОКСИ-13-ДИМЕТИЛАМИНО-5,7α-6,11β(Н)-ГВАЙ-3(4)-ЕН-6,12-ОЛИДА, ЛИОФИЛИЗИРОВАННОГО, ПРОТИВООПУХОЛЕВОГО СРЕДСТВА "АРГЛАБИН", ОБЛАДАЮЩЕГО РАДИОСЕНСИБИЛИЗИРУЮЩИМ И ИММУНОМОДУЛИРУЮЩИМ СВОЙСТВАМИ | |
ATE524451T1 (de) | Substituierte n-benzo ädü isoxazol-3-yl-amin- derivative als inhibitoren von mglur5, serotonin- (5-ht) und noradrenalin rezeptoren und deren verwendung zur herstellung von arzneimitteln | |
ATE465157T1 (de) | Neues verfahren zur herstellung von nebivololzwischenprodukten | |
ATE541037T1 (de) | Verfahren zur trennung und reinigung von nukleinsäure | |
Pyo et al. | Large-scale purification of 13-dehydroxybaccatin III and 10-deacetylpaclitaxel, semi-synthetic precursors of paclitaxel, from cell cultures of Taxus chinensis | |
Bonsignore et al. | New, readily available organocatalysts for the enantioselective reduction of α-imino-and β-imino esters | |
WO2001051476A3 (en) | Production of taxol and taxanes | |
DE602005005980D1 (de) | Verfahren zur isolierung von ergotalkaloiden aus ergot | |
Im Jeon et al. | Optimal temperature control in fractional precipitation for paclitaxel pre-purification | |
Dei et al. | Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1, 3-dioxolan-4-yl)-pyrrolidine, 1-methyl-2-(2-methyl-1, 3-oxathiolan-5-yl) pyrrolidine and of Their iodomethylates | |
Walker et al. | Synthesis of (±)-8-oxa-3-azabicyclo [3.2. 1] octan-2-thione and (±)-2-oxa-5-azabicyclo [2.2. 1] heptan-6-thione: potential synthons for the preparation of novel heteroaryl-annulated bicyclic morpholines | |
Gao et al. | Synthesis, isolation, stereostructure and cytotoxicity of paclitaxel analogs from cephalomannine | |
CN103288785B (zh) | 一种紫杉醇废渣的处理方法 | |
CN103588736B (zh) | 13-乙酰基-9-羟基巴卡亭iii的提取分离方法 |