DE602004012418D1 - Piperazinderivate und anwendungsverfahren - Google Patents

Piperazinderivate und anwendungsverfahren

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Publication number
DE602004012418D1
DE602004012418D1 DE602004012418T DE602004012418T DE602004012418D1 DE 602004012418 D1 DE602004012418 D1 DE 602004012418D1 DE 602004012418 T DE602004012418 T DE 602004012418T DE 602004012418 T DE602004012418 T DE 602004012418T DE 602004012418 D1 DE602004012418 D1 DE 602004012418D1
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DE
Germany
Prior art keywords
diseases
compounds
processes
treatment
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004012418T
Other languages
English (en)
Other versions
DE602004012418T2 (de
Inventor
Jian J Chen
Ben C Askew
Kaustav Biswas
Jennifer N Chau
Amico Derin C D
Scott Harried
Thomas Nguyen
Wenyuan Qian
Jiawang Zhu
Christopher H Fotsch
Nianhe Han
Aiwen Li
Qingyian Liu
Nobuko Nishimura
Rana Nomak
Tanya Peterkin
Babak Riahi
Kevin Yang
Chester Chenguang Yuan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
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Application filed by Amgen Inc filed Critical Amgen Inc
Publication of DE602004012418D1 publication Critical patent/DE602004012418D1/de
Application granted granted Critical
Publication of DE602004012418T2 publication Critical patent/DE602004012418T2/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
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    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
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    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
DE602004012418T 2003-06-20 2004-06-21 Piperazinderivate und anwendungsverfahren Active DE602004012418T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48030303P 2003-06-20 2003-06-20
US480303P 2003-06-20
PCT/US2004/019935 WO2005061467A2 (en) 2003-06-20 2004-06-21 Piperazine derivatives as bradykinin antagonists

Publications (2)

Publication Number Publication Date
DE602004012418D1 true DE602004012418D1 (de) 2008-04-24
DE602004012418T2 DE602004012418T2 (de) 2008-06-19

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Family Applications (1)

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DE602004012418T Active DE602004012418T2 (de) 2003-06-20 2004-06-21 Piperazinderivate und anwendungsverfahren

Country Status (18)

Country Link
US (2) US7393852B2 (de)
EP (1) EP1656355B1 (de)
JP (1) JP2007516176A (de)
KR (1) KR20060036399A (de)
CN (1) CN1849121A (de)
AT (1) ATE388708T1 (de)
AU (1) AU2004303757B2 (de)
BR (1) BRPI0411673A (de)
CA (1) CA2529314A1 (de)
DE (1) DE602004012418T2 (de)
ES (1) ES2302079T3 (de)
IL (1) IL172419A0 (de)
IS (1) IS8175A (de)
MX (1) MXPA05013469A (de)
NO (1) NO20060278L (de)
RU (1) RU2006101541A (de)
WO (1) WO2005061467A2 (de)
ZA (1) ZA200600579B (de)

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US20040073617A1 (en) * 2000-06-19 2004-04-15 Milliken Walter Clark Hash-based systems and methods for detecting and preventing transmission of unwanted e-mail
US7200105B1 (en) * 2001-01-12 2007-04-03 Bbn Technologies Corp. Systems and methods for point of ingress traceback of a network attack
JP2007516176A (ja) * 2003-06-20 2007-06-21 アムジエン・インコーポレーテツド ピペラジン誘導体及び使用方法
WO2006019975A1 (en) * 2004-07-15 2006-02-23 Amgen Inc. 1,2,3,4-tetrahydropyrazin-2-yl acetamides and their use as bradykinin antagonists for the treatment of inflammation related disorders
US20060217362A1 (en) * 2004-12-29 2006-09-28 Tung Jay S Novel compounds useful for bradykinin B1 receptor antagonism
US20060173037A1 (en) * 2005-01-10 2006-08-03 Nathalie Schlienger Aminophenyl derivatives as selective androgen receptor modulators
US8059551B2 (en) * 2005-02-15 2011-11-15 Raytheon Bbn Technologies Corp. Method for source-spoofed IP packet traceback
US8008291B2 (en) * 2008-02-29 2011-08-30 Mimetica Pty Ltd 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5 receptor antagonists
US8377925B2 (en) 2008-02-29 2013-02-19 Mimetica Pty Ltd Methods of modulating the activity of the MC5 receptor and treatment of conditions related to this receptor
US8343958B2 (en) 2008-02-29 2013-01-01 Mimetica Pty Ltd 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5-receptor antagonists
EP2116618A1 (de) 2008-05-09 2009-11-11 Agency for Science, Technology And Research Diagnose und Behandlung des Kawasaki-Syndroms
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WO2005061467A2 (en) 2005-07-07
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AU2004303757A1 (en) 2005-07-07
MXPA05013469A (es) 2006-03-09
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ATE388708T1 (de) 2008-03-15
US20090054460A1 (en) 2009-02-26
KR20060036399A (ko) 2006-04-28
RU2006101541A (ru) 2006-06-10
CN1849121A (zh) 2006-10-18
EP1656355A2 (de) 2006-05-17
CA2529314A1 (en) 2005-07-07
JP2007516176A (ja) 2007-06-21
WO2005061467A3 (en) 2006-06-01
US20050014749A1 (en) 2005-01-20
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NO20060278L (no) 2006-03-15
US7393852B2 (en) 2008-07-01

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