DE60142913D1 - Arzneilösungen enthaltend modafinilverbindungen - Google Patents

Arzneilösungen enthaltend modafinilverbindungen

Info

Publication number
DE60142913D1
DE60142913D1 DE60142913T DE60142913T DE60142913D1 DE 60142913 D1 DE60142913 D1 DE 60142913D1 DE 60142913 T DE60142913 T DE 60142913T DE 60142913 T DE60142913 T DE 60142913T DE 60142913 D1 DE60142913 D1 DE 60142913D1
Authority
DE
Germany
Prior art keywords
modafinil compounds
drug solutions
solutions contain
contain modafinil
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60142913T
Other languages
German (de)
English (en)
Inventor
Martin J Jacobs
Bradley T Mcintyre
Piyush R Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon LLC
Original Assignee
Cephalon LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon LLC filed Critical Cephalon LLC
Application granted granted Critical
Publication of DE60142913D1 publication Critical patent/DE60142913D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60142913T 2000-10-11 2001-10-11 Arzneilösungen enthaltend modafinilverbindungen Expired - Lifetime DE60142913D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23948800P 2000-10-11 2000-10-11
US09/974,473 US6489363B2 (en) 2000-10-11 2001-10-10 Pharmaceutical solutions of modafinil compounds
PCT/US2001/031685 WO2002030413A1 (en) 2000-10-11 2001-10-11 Pharmaceutical solutions of modafinil compounds

Publications (1)

Publication Number Publication Date
DE60142913D1 true DE60142913D1 (de) 2010-10-07

Family

ID=26932612

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60142913T Expired - Lifetime DE60142913D1 (de) 2000-10-11 2001-10-11 Arzneilösungen enthaltend modafinilverbindungen

Country Status (21)

Country Link
US (1) US6489363B2 (enExample)
EP (1) EP1324755B1 (enExample)
JP (1) JP2004510816A (enExample)
KR (1) KR100846914B1 (enExample)
CN (1) CN100518726C (enExample)
AT (1) ATE478662T1 (enExample)
AU (2) AU9678501A (enExample)
BG (1) BG66221B1 (enExample)
BR (1) BR0114813A (enExample)
CA (1) CA2425218C (enExample)
CZ (1) CZ2003966A3 (enExample)
DE (1) DE60142913D1 (enExample)
EA (1) EA005572B1 (enExample)
HU (1) HU229424B1 (enExample)
IL (2) IL155263A0 (enExample)
MX (1) MXPA03003150A (enExample)
NO (1) NO333096B1 (enExample)
NZ (1) NZ525166A (enExample)
PL (1) PL214879B1 (enExample)
SK (1) SK287436B6 (enExample)
WO (1) WO2002030413A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919378B2 (en) * 2000-10-11 2005-07-19 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
KR100911952B1 (ko) * 2000-10-11 2009-08-13 세파론, 인코포레이티드 모다피닐 화합물을 포함하는 조성물
US6992219B2 (en) * 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
US20040116532A1 (en) 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
FR2849029B1 (fr) 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
WO2004082624A2 (en) * 2003-03-17 2004-09-30 Neurohealing Pharmaceuticals, Inc. Modafinil-based neurorehabilitation of impaired neurological function associated with injury
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
US8153159B2 (en) * 2003-09-18 2012-04-10 Cephalon, Inc. Modafinil modified release pharmaceutical compositions
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
US20060024370A1 (en) * 2004-07-29 2006-02-02 Cephalon France Modafinil oral lyophilizate
BRPI0500520A (pt) * 2005-02-16 2006-09-26 Henry Jun Suzuki uso de agentes flavorizantes aromáticos de alto ponto de fusão como agentes solubilizantes ou inibidores de cristalização em composições farmacêuticas
US20090123545A1 (en) * 2005-07-21 2009-05-14 Ron Eyal S Rapid Onset and Short Term Modafinil Compositions and Methods of Use Thereof
WO2008021341A2 (en) 2006-08-14 2008-02-21 Neurohealing Pharmaceuticals, Inc. Modafinil-based treatment for premature ejaculation
US8173169B2 (en) * 2007-07-11 2012-05-08 Hikma Pharmaceuticals Formulation and process for the preparation of modafinil
CA2629979A1 (en) * 2008-04-25 2009-10-25 Pharmascience Inc. Novel resveratrol compositions
FR2987266B1 (fr) 2012-02-28 2014-12-19 Debregeas Et Associes Pharma Procede d'obtention d'une composition pharmaceutique a base de modafinil, composition pharmaceutique ainsi obtenue et son application
FR2987265B1 (fr) 2012-02-28 2014-02-28 Debregeas Et Associes Pharma Composition pharmaceutique sous forme de sirop a base de modafinil, son procede de fabrication et son application
MX2015004973A (es) * 2012-10-18 2015-07-17 Abbvie Inc Formulaciones de compuestos derivados de pirimidindiona.
US9616068B2 (en) 2014-10-27 2017-04-11 Pohela LLC Animal training using cognitive enhancement

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1584462A (en) 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
FR2663225B1 (fr) 1990-06-14 1994-11-04 Lafon Labor Nouvelle utilisation du modafinil.
US5618845A (en) 1994-10-06 1997-04-08 Cephalon, Inc. Acetamide derivative having defined particle size
FR2771004B1 (fr) 1997-11-19 2000-02-18 Inst Curie Utilisation de derives de benzhydryl sulfinyle pour la fabrication de medicaments ayant un effet eveillant dans des situations de troubles de la vigilance d'origine medicamenteuse
US6200968B1 (en) 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
US20010034373A1 (en) 2000-02-09 2001-10-25 Matthew Miller Low dose modafinil for enhancement of cognitive function

Also Published As

Publication number Publication date
ATE478662T1 (de) 2010-09-15
AU2001296785B2 (en) 2006-03-16
BG107720A (bg) 2004-01-30
HUP0302478A3 (en) 2005-05-30
HU229424B1 (hu) 2013-12-30
IL155263A (en) 2007-07-24
NO20031648L (no) 2003-06-04
NZ525166A (en) 2006-10-27
HUP0302478A2 (hu) 2003-11-28
BR0114813A (pt) 2005-01-25
US6489363B2 (en) 2002-12-03
AU9678501A (en) 2002-04-22
CZ2003966A3 (cs) 2003-09-17
SK287436B6 (sk) 2010-09-07
PL214879B1 (pl) 2013-09-30
SK4402003A3 (en) 2003-09-11
EA005572B1 (ru) 2005-04-28
MXPA03003150A (es) 2003-07-14
US20020099097A1 (en) 2002-07-25
HK1057336A1 (en) 2004-04-02
PL361134A1 (en) 2004-09-20
CN1468096A (zh) 2004-01-14
CA2425218A1 (en) 2002-04-18
KR20030055279A (ko) 2003-07-02
NO333096B1 (no) 2013-03-04
EP1324755A1 (en) 2003-07-09
EP1324755B1 (en) 2010-08-25
CN100518726C (zh) 2009-07-29
CA2425218C (en) 2010-10-05
NO20031648D0 (no) 2003-04-10
JP2004510816A (ja) 2004-04-08
KR100846914B1 (ko) 2008-07-17
BG66221B1 (bg) 2012-06-29
EA200300450A1 (ru) 2003-08-28
IL155263A0 (en) 2003-11-23
WO2002030413A1 (en) 2002-04-18

Similar Documents

Publication Publication Date Title
DE60142913D1 (de) Arzneilösungen enthaltend modafinilverbindungen
DE60322412D1 (de) Pharmazeutische feste Dispersionen von Modafinil-Verbindungen
ATE512163T1 (de) Verabreichung von mitteln zur behandlung von entzündungen
UY27175A1 (es) Nueva sal succinato de o-desmetil- venlafaxina
BR0313747A (pt) Inibidores de transcriptase reversa de não-nucleosìdeo
NO324227B1 (no) Cyclopropyl-kondenserte pyrrolidin-baserte forbindelser, farmasoytiske blandinger og kombinasjoner inneholdende slike samt anvendelse av slike for fremstilling av medikamenter for behandling av sykdommer
DE60313597D1 (de) Topische pharmazeutische zusammensetzungen mit proanthocyanidinen, glycyrrhetinic säure und telmesteine zur behandlung von dermatitis
AR027355A1 (es) Acidos tiazolidincarboxilicos
CY1108932T1 (el) Ενωσεις 4-(ετεροκυκλυλ)-βενζολοσουλφοξιμινης για την θεραπευτικη αγωγη φλεγμονωδων ασθενειων
ATE350377T1 (de) Substituierte 3-pyrrolidin-indol-derivate
SE0101932D0 (sv) Pharmaceutical combinations
SE9802208D0 (sv) Novel compounds
EA200501821A1 (ru) Фармацевтическая комбинация, содержащая модафинил и другой лекарственный препарат
WO2003066597A3 (en) Guanidino compounds
HUP0200152A2 (hu) KQT1 csatornák gátlóinak alkalmazása parazita férgek és ektoparaziták által okozott betegségek kezelésére alkalmas gyógyszerkészítmények előállítására
DE60137069D1 (de) Arzneizusammensetzungen enthaltend modafinilverbindungen
SE0001916D0 (sv) Novel formulation
HRP20080597T3 (en) Cancer combination therapy comprising azd2171 and zd1839
SE0000303D0 (sv) Novel compounds
DK1537132T3 (da) Salt af mortin-6-glucuronid
CY1105165T1 (el) Φαρμακευτικη συνθεση που πepιλαμβανει συνδυασμο μετφορμινης και 4-οξοβουτανικου οξεος και η χρηση αυτης για τη θepαπεια του διαβητη
ATE241640T1 (de) Fusidinsäure-derivate
SE0300535D0 (sv) Treatment of burns
EA200501514A1 (ru) Сочетания действующих веществ и способы лечения злоупотребления алкоголем
DE50304524D1 (de) Arzneimittel enthaltend substituierte 2,5-diaminomethyl-1h-pyrrole