DE60138722D1 - Orale zubereitungen mit vorteilhaften zerfallseigenschaften - Google Patents

Orale zubereitungen mit vorteilhaften zerfallseigenschaften

Info

Publication number
DE60138722D1
DE60138722D1 DE60138722T DE60138722T DE60138722D1 DE 60138722 D1 DE60138722 D1 DE 60138722D1 DE 60138722 T DE60138722 T DE 60138722T DE 60138722 T DE60138722 T DE 60138722T DE 60138722 D1 DE60138722 D1 DE 60138722D1
Authority
DE
Germany
Prior art keywords
water
carmellose
sodium
disintegrant
granule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60138722T
Other languages
English (en)
Inventor
Kazuyuki Fujihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18771855&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60138722(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sumitomo Dainippon Pharma Co Ltd filed Critical Sumitomo Dainippon Pharma Co Ltd
Application granted granted Critical
Publication of DE60138722D1 publication Critical patent/DE60138722D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
DE60138722T 2000-09-22 2001-09-14 Orale zubereitungen mit vorteilhaften zerfallseigenschaften Expired - Lifetime DE60138722D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000288234 2000-09-22
PCT/JP2001/007983 WO2002024166A1 (fr) 2000-09-22 2001-09-14 Preparations orales dotees de bonnes caracteristiques de desagregation

Publications (1)

Publication Number Publication Date
DE60138722D1 true DE60138722D1 (de) 2009-06-25

Family

ID=18771855

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60138722T Expired - Lifetime DE60138722D1 (de) 2000-09-22 2001-09-14 Orale zubereitungen mit vorteilhaften zerfallseigenschaften

Country Status (11)

Country Link
US (1) US7727553B2 (de)
EP (2) EP1327440B1 (de)
JP (1) JP4868695B2 (de)
AT (1) ATE431136T1 (de)
AU (1) AU2001286237A1 (de)
CA (2) CA2424001C (de)
DE (1) DE60138722D1 (de)
DK (1) DK1327440T5 (de)
ES (1) ES2325764T3 (de)
TW (2) TWI289062B (de)
WO (1) WO2002024166A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2326078T3 (es) 2002-08-22 2009-09-30 Dainippon Sumitomo Pharma Co., Ltd. Medicamento destinado al sindrome de la disfuncion de integracion.
SE0203778D0 (sv) * 2002-12-09 2002-12-09 Astrazeneca Ab A new oral immediated release dosage form
AU2004249621B2 (en) * 2003-06-23 2009-08-06 Dainippon Sumitomo Pharma Co., Ltd. Therapeutic agent for senile dementia
JP4847320B2 (ja) 2004-02-20 2011-12-28 大日本住友製薬株式会社 統合失調症の記憶・学習機能障害治療薬のｉｎｖｉｖｏスクリーニング方法
EP1886678B1 (de) * 2005-05-18 2017-04-19 Sumitomo Dainippon Pharma Co., Ltd. Stabile tablette mit droxidopa
PT1884242E (pt) * 2005-05-26 2013-05-21 Dainippon Sumitomo Pharma Co Composição farmacêutica compreendendo lurasidona
KR101328857B1 (ko) * 2005-06-13 2013-11-13 다이닛본 스미토모 세이야꾸 가부시끼가이샤 가용화 제제
WO2007018190A1 (ja) * 2005-08-10 2007-02-15 Shionogi & Co., Ltd. 苦味抑制製剤
US20080274178A1 (en) * 2005-08-10 2008-11-06 Shionogi & Co., Ltd. Orally Disintegrating Tablet
EP1973531A2 (de) * 2006-01-02 2008-10-01 Rubicon Research Private Limited Pharmazeutische zusammensetzungen
PE20081891A1 (es) * 2007-03-22 2008-12-27 Opko Health Inc Formulaciones de comprimidos que contienen sales de 8-[{1-(3,5-bis-(trifluorometil)fenil)-etoxi}-metil]-8-fenil-1,7-diaza-spiro[4.5]decan-2-ona y comprimidos elaborados a partir de estas
US20090110716A1 (en) 2007-10-31 2009-04-30 Frank Bunick Orally disintegrative dosage form
CN101945657B (zh) 2008-02-11 2015-04-22 大日本住友制药株式会社 具有改善的溶出性的片剂
KR101618388B1 (ko) 2008-06-13 2016-05-04 다이닛본 스미토모 세이야꾸 가부시끼가이샤 구강 내 급속 붕해 정제 및 이의 제조 방법
ES2855426T3 (es) * 2008-09-17 2021-09-23 Mylan Inc Granulados, proceso de preparación de los mismos y productos farmacéuticos que los contienen
US8784781B2 (en) 2009-09-24 2014-07-22 Mcneil-Ppc, Inc. Manufacture of chewing gum product with radiofrequency
US8858210B2 (en) 2009-09-24 2014-10-14 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
US8258139B2 (en) 2010-11-08 2012-09-04 Dainippon Sumitomo Pharma Co., Ltd. Method of treatment for mental disorders
WO2012107890A2 (en) * 2011-02-10 2012-08-16 Ranbaxy Laboratories Limited Crystalline forms of lurasidone hydrochloride
US9433620B2 (en) * 2011-05-13 2016-09-06 Cadila Healthcare Limited Pharmaceutical compositions of lurasidone
EP2827767B1 (de) 2012-03-21 2020-09-30 Koninklijke Philips N.V. Verfahren und vorrichtung zur bereitstellung einer visuellen darstellung der schlafqualität auf der basis von ekg-signalen
US9511028B2 (en) * 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
JP6007169B2 (ja) * 2012-11-30 2016-10-12 大原薬品工業株式会社 アリピプラゾール無水物を含有する固形製剤の製造方法
WO2014090386A1 (en) 2012-12-11 2014-06-19 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Orally disintegrating tablet containing asenapine
JP2014129238A (ja) * 2012-12-28 2014-07-10 Lion Corp エトドラク含有固形製剤
JP6037824B2 (ja) * 2012-12-28 2016-12-07 ライオン株式会社 エトドラク含有固形製剤
ES2750323T3 (es) 2014-01-10 2020-03-25 Johnson & Johnson Consumer Inc Método para la fabricación de un comprimido mediante radiofrecuencia y partículas recubiertas con pérdida
WO2016012898A1 (en) 2014-07-25 2016-01-28 Lupin Limited Oral pharmaceutical composition of lurasidone
WO2016139683A2 (en) * 2015-03-05 2016-09-09 Jubilant Generics Limited Pharmaceutical compositions of lurasidone and process for preparing the same
US10966928B2 (en) 2016-03-25 2021-04-06 Universiteit Gent Oral dosage form
EP3892263A1 (de) 2016-03-25 2021-10-13 Universiteit Gent Orale darreichungsform
JPWO2017170858A1 (ja) * 2016-03-31 2019-02-14 インターセプト ファーマシューティカルズ， インコーポレイテッド 溶出性に優れた経口製剤
JPWO2018043613A1 (ja) * 2016-08-31 2019-06-24 大日本住友製薬株式会社 水性懸濁型製剤
US11260055B2 (en) 2017-01-11 2022-03-01 Piramal Enterprises Limited Oral pharmaceutical composition of lurasidone and preparation thereof
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
AT17300U3 (de) * 2020-12-03 2022-02-15 G L Pharma Gmbh Feste orale pharmazeutische Zusammensetzung
TW202333719A (zh) * 2021-11-04 2023-09-01 大陸商上海博志研新藥物技術有限公司 鹽酸魯拉西酮口溶膜組合物、其製備方法及用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61148114A (ja) 1984-11-15 1986-07-05 Teijin Ltd ニフエジピンの顆粒剤
JP2800953B2 (ja) * 1990-07-06 1998-09-21 住友製薬株式会社 新規なイミド誘導体
JPH04305526A (ja) * 1991-03-28 1992-10-28 Morishita Roussel Kk 薬剤組成物
ZA939565B (en) * 1993-12-21 1994-08-11 Applied Analytical Ind Inc Method for preparing low dose pharmaceutical products.
US5972383A (en) * 1994-03-02 1999-10-26 Eli Lilly And Company Solid orally administerable raloxifene hydrochloride pharmaceutical formulation
US5811120A (en) 1994-03-02 1998-09-22 Eli Lilly And Company Solid orally administerable raloxifene hydrochloride pharmaceutical formulation
US5994348A (en) 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
EP0839526A3 (de) * 1996-10-31 1999-01-07 Takeda Chemical Industries, Ltd. Festes pharmazeutisches Präparat mit schneller Auflösungs- oder Disintegrationeigenschaften
TW482675B (en) * 1997-01-31 2002-04-11 Green Cross Corp Compositions for oral administration containing pyridazinone compounds technical field of the invention
KR100775154B1 (ko) 1997-12-19 2007-11-12 스미스클라인 비참 코포레이션 바이트-분산성 정제의 제조 방법
US6465009B1 (en) 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
JP4438121B2 (ja) 1998-04-27 2010-03-24 大正製薬株式会社 口腔内速崩錠及びその製造方法
KR100267576B1 (ko) * 1998-07-25 2000-11-01 허계성 활성성분을 분리함유한 츄잉 연질정제 및 그의 제조방법
JP2000086503A (ja) 1998-09-07 2000-03-28 Pola Chem Ind Inc 錠剤医薬組成物
JP2000086509A (ja) * 1998-09-14 2000-03-28 Taisho Yakuhin Kogyo Kk ソファルコン含有製剤の製造方法
US6245352B1 (en) * 1999-04-27 2001-06-12 Eli Lilly And Company Pharmaceutical formulation

Also Published As

Publication number Publication date
EP1327440B1 (de) 2009-05-13
CA2424001A1 (en) 2003-03-20
JP4868695B2 (ja) 2012-02-01
EP1974724A3 (de) 2008-11-12
CA2424001C (en) 2013-10-22
EP1974724A2 (de) 2008-10-01
ES2325764T3 (es) 2009-09-16
AU2001286237A1 (en) 2002-04-02
DK1327440T5 (da) 2009-09-07
TWI289063B (en) 2007-11-01
CA2824077A1 (en) 2002-03-28
US20040028741A1 (en) 2004-02-12
JPWO2002024166A1 (ja) 2004-01-29
TWI289062B (en) 2007-11-01
WO2002024166A1 (fr) 2002-03-28
US7727553B2 (en) 2010-06-01
ATE431136T1 (de) 2009-05-15
EP1327440A1 (de) 2003-07-16
EP1327440A4 (de) 2006-02-01
TW200524642A (en) 2005-08-01
DK1327440T3 (da) 2009-06-08
CA2824077C (en) 2016-01-26

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