RU96116411A - Быстро распадающаяся готовая препаративная форма трамадола или соли трамадола - Google Patents
Быстро распадающаяся готовая препаративная форма трамадола или соли трамадолаInfo
- Publication number
- RU96116411A RU96116411A RU96116411/14A RU96116411A RU96116411A RU 96116411 A RU96116411 A RU 96116411A RU 96116411/14 A RU96116411/14 A RU 96116411/14A RU 96116411 A RU96116411 A RU 96116411A RU 96116411 A RU96116411 A RU 96116411A
- Authority
- RU
- Russia
- Prior art keywords
- tramadol
- salt
- dispersable
- ready
- quickly
- Prior art date
Links
- TVYLLZQTGLZFBW-ZBFHGGJFSA-N Tramadol Chemical compound COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-ZBFHGGJFSA-N 0.000 title claims 10
- 229960004380 Tramadol Drugs 0.000 title claims 5
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drugs Drugs 0.000 title 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 2
- 239000008108 microcrystalline cellulose Substances 0.000 claims 2
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 2
- 239000008107 starch Substances 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 229940032147 Starch Drugs 0.000 claims 1
- 239000007884 disintegrant Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
Claims (5)
1. Не содержащие связующих веществ таблетки трамадола либо соли трамадола, включающие микрокристаллическую целлюлозу и трамадол либо соль трамадола в массовом соотношении по крайней мере 2:1, для орального введения.
2. Таблетки по п. 1, отличающиеся тем, что массовое соотношение между микрокристаллической целлюлозой и трамадолом либо солью трамадола составляет по крайней мере 3:1, предпочтительно по крайней мере 4:1.
3. Таблетки по одному или обоим пп. 1-2, отличающиеся тем, что таблетки содержат крахмал.
4. Таблетки по п. 3, отличающиеся тем, что массовое соотношение между крахмалом и трамадолом либо солью трамадола составляет 1:1.
5. Таблетки по одному или нескольким пп. 1-5, отличающиеся тем, что таблетки содержат 0,5-10 мас. % по крайней мере одного вещества, вызывающего дезинтеграцию, в качестве возможного ингредиента.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19530575.2 | 1995-08-19 | ||
| DE19530575A DE19530575A1 (de) | 1995-08-19 | 1995-08-19 | Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU96116411A true RU96116411A (ru) | 1998-11-10 |
| RU2174837C2 RU2174837C2 (ru) | 2001-10-20 |
Family
ID=7769912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU96116411/14A RU2174837C2 (ru) | 1995-08-19 | 1996-08-16 | Быстрораспадающаяся готовая препаративная форма трамадола или соли трамадола |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US5776492A (ru) |
| EP (1) | EP0759296B1 (ru) |
| JP (1) | JP4074675B2 (ru) |
| CN (1) | CN1102385C (ru) |
| AR (1) | AR003476A1 (ru) |
| AT (1) | ATE205708T1 (ru) |
| AU (1) | AU703310B2 (ru) |
| BR (1) | BR9604034A (ru) |
| CA (1) | CA2182939C (ru) |
| CZ (1) | CZ289167B6 (ru) |
| DE (2) | DE19530575A1 (ru) |
| DK (1) | DK0759296T3 (ru) |
| ES (1) | ES2164198T3 (ru) |
| GR (1) | GR3036720T3 (ru) |
| HK (1) | HK1010100A1 (ru) |
| HU (1) | HU227360B1 (ru) |
| IL (1) | IL119080A (ru) |
| MY (1) | MY113908A (ru) |
| NO (1) | NO313486B1 (ru) |
| NZ (1) | NZ299141A (ru) |
| PE (1) | PE8298A1 (ru) |
| PL (1) | PL184785B1 (ru) |
| PT (1) | PT759296E (ru) |
| RU (1) | RU2174837C2 (ru) |
| SI (1) | SI0759296T1 (ru) |
| SK (1) | SK281779B6 (ru) |
| UA (1) | UA41392C2 (ru) |
| UY (1) | UY24308A1 (ru) |
| ZA (1) | ZA966985B (ru) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100389752C (zh) * | 1978-04-21 | 2008-05-28 | 莱博法姆公司 | 控释组合物 |
| US5989589A (en) * | 1997-10-24 | 1999-11-23 | Cartilier; Louis | Cross-linked cellulose as a tablet excipient |
| JP2002505269A (ja) * | 1998-03-06 | 2002-02-19 | エウランド インターナショナル ソシエタ ペル アチオニ | 急速崩壊錠剤 |
| SE9802973D0 (sv) * | 1998-09-03 | 1998-09-03 | Astra Ab | Immediate release tablet |
| GB9904911D0 (en) * | 1999-03-03 | 1999-04-28 | Scherer Ltd R P | Pharmaceutical compositions |
| ATE279186T1 (de) | 1999-08-31 | 2004-10-15 | Gruenenthal Gmbh | Retardierte darreichungsform enthaltend tramadolsaccharinat |
| DE19940944B4 (de) | 1999-08-31 | 2006-10-12 | Grünenthal GmbH | Retardierte, orale, pharmazeutische Darreichungsformen |
| DE19940740A1 (de) * | 1999-08-31 | 2001-03-01 | Gruenenthal Gmbh | Pharmazeutische Salze |
| US8487002B2 (en) | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
| ATE400819T1 (de) * | 2002-10-25 | 2008-07-15 | Labopharm Inc | Zubereitungen mit kontrollierter freisetzung |
| AR045972A1 (es) * | 2002-10-25 | 2005-11-23 | Labopharm Inc | Formulaciones de tramadol de liberacion sostenida con eficacia de 24 horas |
| CN1942175B (zh) * | 2002-10-25 | 2010-05-26 | 莱博法姆公司 | 24小时有效的曲马多缓释制剂 |
| TWI319713B (en) | 2002-10-25 | 2010-01-21 | Sustained-release tramadol formulations with 24-hour efficacy | |
| US20040265375A1 (en) * | 2003-04-16 | 2004-12-30 | Platteeuw Johannes J. | Orally disintegrating tablets |
| DK1663182T4 (da) | 2003-09-12 | 2020-02-17 | Amgen Inc | Hurtigt opløsende formulering af cinacalcet HCI |
| US20060172006A1 (en) * | 2003-10-10 | 2006-08-03 | Vincent Lenaerts | Sustained-release tramadol formulations with 24-hour clinical efficacy |
| US8022053B2 (en) * | 2004-11-02 | 2011-09-20 | Bayer Schering Pharma Aktiengesellschaft | Oral solid dosage forms containing a low dose of estradiol |
| JP5269595B2 (ja) | 2005-09-09 | 2013-08-21 | アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー | １日１回投与用トラゾドン組成物 |
| US20090004248A1 (en) * | 2007-06-29 | 2009-01-01 | Frank Bunick | Dual portion dosage lozenge form |
| ITMI20130210A1 (it) | 2013-02-14 | 2014-08-15 | Menarini Lab | Composizioni farmaceutiche contenenti dexketoprofene e tramadolo |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3181998A (en) | 1960-08-12 | 1965-05-04 | Joseph L Kanig | Tablet disintegration |
| DE1617343B2 (de) | 1967-04-21 | 1976-04-22 | CH. Boehringer Sohn, 6507 Ingelheim | Traegermasse fuer arzneimitteltabletten |
| US4517179A (en) * | 1983-04-29 | 1985-05-14 | Pennwalt Corporation | Rapid dissolving, uniform drug compositions and their preparation |
| US4600579A (en) | 1983-06-07 | 1986-07-15 | Mallinckrodt, Inc. | N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same |
| EP0147780A3 (en) * | 1984-01-03 | 1987-03-11 | Merck & Co. Inc. | Drug delivery device |
| WO1987001936A1 (en) | 1985-09-25 | 1987-04-09 | Gerhard Gergely | Desintegration tablet and process for its manufacture |
| CH675537A5 (ru) | 1988-03-25 | 1990-10-15 | Ciba Geigy Ag | |
| US5211957A (en) * | 1988-03-25 | 1993-05-18 | Ciba-Geigy Corporation | Solid rapidly disintegrating dosage form |
| US5254355A (en) | 1992-05-29 | 1993-10-19 | Kraft General Foods, Inc. | Process for beverage tablets and products therefrom |
| DE4329794C2 (de) * | 1993-09-03 | 1997-09-18 | Gruenenthal Gmbh | Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung |
-
1995
- 1995-08-19 DE DE19530575A patent/DE19530575A1/de not_active Withdrawn
-
1996
- 1996-05-29 MY MYPI96002047A patent/MY113908A/en unknown
- 1996-07-17 SI SI9630318T patent/SI0759296T1/xx unknown
- 1996-07-17 DE DE59607710T patent/DE59607710D1/de not_active Revoked
- 1996-07-17 ES ES96111483T patent/ES2164198T3/es not_active Expired - Lifetime
- 1996-07-17 DK DK96111483T patent/DK0759296T3/da active
- 1996-07-17 EP EP96111483A patent/EP0759296B1/de not_active Revoked
- 1996-07-17 PT PT96111483T patent/PT759296E/pt unknown
- 1996-07-17 AT AT96111483T patent/ATE205708T1/de not_active IP Right Cessation
- 1996-07-30 BR BR9604034A patent/BR9604034A/pt not_active Application Discontinuation
- 1996-08-06 AU AU61941/96A patent/AU703310B2/en not_active Ceased
- 1996-08-07 CN CN96110917A patent/CN1102385C/zh not_active Expired - Fee Related
- 1996-08-08 CA CA002182939A patent/CA2182939C/en not_active Expired - Fee Related
- 1996-08-08 NZ NZ299141A patent/NZ299141A/en not_active IP Right Cessation
- 1996-08-09 CZ CZ19962359A patent/CZ289167B6/cs not_active IP Right Cessation
- 1996-08-09 SK SK1042-96A patent/SK281779B6/sk not_active IP Right Cessation
- 1996-08-09 JP JP21122196A patent/JP4074675B2/ja not_active Expired - Fee Related
- 1996-08-09 PE PE1996000597A patent/PE8298A1/es not_active Application Discontinuation
- 1996-08-12 AR ARP960103957A patent/AR003476A1/es not_active Application Discontinuation
- 1996-08-14 PL PL96315749A patent/PL184785B1/pl not_active IP Right Cessation
- 1996-08-14 UY UY24308A patent/UY24308A1/es not_active IP Right Cessation
- 1996-08-16 IL IL11908096A patent/IL119080A/en not_active IP Right Cessation
- 1996-08-16 NO NO19963430A patent/NO313486B1/no not_active IP Right Cessation
- 1996-08-16 RU RU96116411/14A patent/RU2174837C2/ru not_active IP Right Cessation
- 1996-08-16 HU HU9602266A patent/HU227360B1/hu not_active IP Right Cessation
- 1996-08-16 ZA ZA9606985A patent/ZA966985B/xx unknown
- 1996-08-19 UA UA96083292A patent/UA41392C2/ru unknown
- 1996-08-19 US US08/699,623 patent/US5776492A/en not_active Expired - Lifetime
-
1998
- 1998-09-25 HK HK98110961A patent/HK1010100A1/xx not_active IP Right Cessation
-
2001
- 2001-09-26 GR GR20010401577T patent/GR3036720T3/el not_active IP Right Cessation
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