DE60136217D1 - Verfahren und vorrichtung zum identifizieren von bioaerosolteilchen in der luft - Google Patents

Verfahren und vorrichtung zum identifizieren von bioaerosolteilchen in der luft

Info

Publication number
DE60136217D1
DE60136217D1 DE60136217T DE60136217T DE60136217D1 DE 60136217 D1 DE60136217 D1 DE 60136217D1 DE 60136217 T DE60136217 T DE 60136217T DE 60136217 T DE60136217 T DE 60136217T DE 60136217 D1 DE60136217 D1 DE 60136217D1
Authority
DE
Germany
Prior art keywords
bioaerosol particles
bioaerosol
particles
fluorescence
air
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60136217T
Other languages
English (en)
Inventor
Michael Anthony Stowers
Arjan Laurens Wuijckhuijse
Johannes Cornelis Marijnissen
Charles Eliza Kientz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Technische Universiteit Delft
Original Assignee
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Technische Universiteit Delft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO, Technische Universiteit Delft filed Critical Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Application granted granted Critical
Publication of DE60136217D1 publication Critical patent/DE60136217D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • G01N15/01—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means, e.g. by light scattering, diffraction, holography or imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0445—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers
DE60136217T 2000-12-15 2001-12-14 Verfahren und vorrichtung zum identifizieren von bioaerosolteilchen in der luft Expired - Lifetime DE60136217D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1016887A NL1016887C2 (nl) 2000-12-15 2000-12-15 Werkwijze en inrichting voor het detecteren en identificeren van bio-aÙrosoldeeltjes in de lucht.
PCT/NL2001/000914 WO2002052246A2 (en) 2000-12-15 2001-12-14 Method and device for detecting and identifying bio-aerosol particles in the air

Publications (1)

Publication Number Publication Date
DE60136217D1 true DE60136217D1 (de) 2008-11-27

Family

ID=19772588

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60136217T Expired - Lifetime DE60136217D1 (de) 2000-12-15 2001-12-14 Verfahren und vorrichtung zum identifizieren von bioaerosolteilchen in der luft

Country Status (16)

Country Link
US (1) US6806464B2 (de)
EP (1) EP1342256B1 (de)
JP (1) JP4145651B2 (de)
KR (1) KR100871938B1 (de)
CN (1) CN1296963C (de)
AT (1) ATE411611T1 (de)
AU (1) AU2002226802A1 (de)
CA (1) CA2431255C (de)
CY (1) CY1108708T1 (de)
DE (1) DE60136217D1 (de)
DK (1) DK1342256T3 (de)
ES (1) ES2315318T3 (de)
IL (2) IL156444A0 (de)
NL (1) NL1016887C2 (de)
PT (1) PT1342256E (de)
WO (1) WO2002052246A2 (de)

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US7800750B2 (en) * 2003-09-19 2010-09-21 The Regents Of The University Of California Optical trap utilizing a reflecting mirror for alignment
WO2005029139A2 (en) * 2003-09-19 2005-03-31 The Regents Of The University Of California A light-force sensor and method for measuring axial optical-trap forces from changes in light momentum along an optic axis
CN100434899C (zh) * 2004-04-29 2008-11-19 中国科学院安徽光学精密机械研究所 气溶胶粒谱(质谱)飞行时间检测方法及装置
US7837937B2 (en) 2004-07-09 2010-11-23 Hamilton Sundstrand Corporation Biological agent detector
US20090218481A1 (en) * 2004-10-07 2009-09-03 Dewalch Norman Binz High-Speed Molecular Analyzer System and Method
US20090084979A1 (en) * 2004-10-07 2009-04-02 Dewalch Norman Binz High-speed molecular analyzer system and method
DE102004061820A1 (de) * 2004-12-22 2006-07-06 Bruker Daltonik Gmbh Lasersystem für die lonisation durch matrixunterstützte Laserdesorption (MALDI) im ultravioletten Spektralbereich (UV)
DE102005005333B4 (de) * 2005-01-28 2008-07-31 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren zur Probennahme und Aerosol-Analyse
US7981365B2 (en) * 2005-09-15 2011-07-19 The United States Of America As Represented By The Secretary Of The Navy Electrospray coating of aerosols for labeling and identification
US7343782B2 (en) * 2006-04-10 2008-03-18 Northrop Grumman Corporation System and method for performing quantifiable release spore testing on bioaerosol detection technologies
WO2008079407A1 (en) * 2006-12-26 2008-07-03 Brigham Young University Serum proteomics system and associated methods
EP2060919A1 (de) * 2007-11-13 2009-05-20 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO MALDI Matrix und MALDI Verfahren
US8031339B2 (en) * 2007-12-21 2011-10-04 Lawrence Livermore National Security, Llc Particle measurement systems and methods
US8513598B2 (en) * 2007-12-21 2013-08-20 Lawrence Livermore National Security, Llc Aerosol mass spectrometry systems and methods
EP2157599A1 (de) * 2008-08-21 2010-02-24 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Verfahren und Vorrichtung zur Identifikation biologischer Materialien
US8358411B2 (en) 2008-12-18 2013-01-22 Biovigilant Systems, Inc. Integrated microbial collector
CN101581698B (zh) * 2009-06-23 2012-08-22 中国科学院安徽光学精密机械研究所 气溶胶场致电离电荷源装置
EP2483649A4 (de) * 2009-09-30 2017-09-06 Genia Photonics Inc. Spektrometer
KR101235145B1 (ko) 2011-06-21 2013-02-20 광주과학기술원 연속파 레이저 및 광전증배관을 이용하는 분광분석장치
KR101523658B1 (ko) * 2014-12-04 2015-05-29 국방과학연구소 형광 에어로졸을 이용한 필터류의 입자 투과 성능 평가 시험 방법 및 장치
US10598668B2 (en) 2015-08-24 2020-03-24 Zeteo Tech, Inc. Coating of aerosol particles using an acoustic coater
KR101787579B1 (ko) 2016-03-31 2017-10-19 주식회사 아스타 근적외선 형광을 이용한 질량 분석 장치 및 방법
CN106248777A (zh) * 2016-08-18 2016-12-21 东南大学 一种常压敞开式进样系统
CN106442449A (zh) * 2016-10-17 2017-02-22 中国科学院合肥物质科学研究院 一种激光诱导荧光探测生物气溶胶装置
NL2018940B1 (en) 2017-05-18 2018-11-28 Biosparq B V Maldi mass spectrometry method
CN107389627B (zh) * 2017-05-26 2020-04-03 清华大学 一种单液滴单细胞培养和细胞代谢产物实时检测装置
CN107841453A (zh) * 2017-11-02 2018-03-27 广州禾信仪器股份有限公司 微生物收集装置及收集检测方法
WO2019133718A1 (en) * 2017-12-29 2019-07-04 The Regents Of The University Of Colorado, A Body Corporate Hi-fidelity bioaerosol condensation capture directly into genomic preservatives
WO2019234544A1 (en) * 2018-06-04 2019-12-12 Dh Technologies Development Pte. Ltd. Lbmfi detector for fluorophore labeled analytes at the taylor cone in esi-ms
JP7233531B2 (ja) * 2018-10-25 2023-03-06 プレアー ソシエテ・アノニム 液滴中の不純物を検出および／または測定するための方法および装置
RU2722066C2 (ru) * 2018-11-19 2020-05-26 Самсунг Электроникс Ко., Лтд. Многоканальный датчик пыли
KR102201084B1 (ko) * 2019-01-21 2021-01-11 연세대학교 산학협력단 황사탐지인자(tdci)를 이용한 에어로졸 유형 분석 시스템
CN110018090B (zh) * 2019-05-17 2020-10-27 中国科学院化学研究所 一种颗粒物化学组分测量系统及方法
EP3990906A4 (de) * 2019-06-29 2023-07-26 Zeteo Tech, Inc. Verfahren und systeme zur detektion von aerosolpartikeln ohne verwendung komplexer organischer maldi-matrizen
KR102100774B1 (ko) * 2019-10-15 2020-04-14 광주과학기술원 초미세입자의 크기-성분 측정 장치 및 크기-성분 측정 방법
NL2027583B1 (en) 2021-02-18 2022-09-15 Deem Consulting B V A time-of-flight mass spectrometer device
CN114459965A (zh) * 2021-12-30 2022-05-10 中船重工安谱（湖北）仪器有限公司 一种气溶胶监测系统及方法
KR102506969B1 (ko) 2023-02-05 2023-03-06 김인영 실내공기 중의 바이오 에어로졸을 신속하게 검출하는 방법

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US4383171A (en) * 1980-11-17 1983-05-10 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Particle analyzing method and apparatus
DE3517667A1 (de) * 1985-05-15 1986-11-20 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Laser-massenspektrometer
GB2177507B (en) * 1985-06-13 1989-02-15 Mitsubishi Electric Corp Laser mass spectroscopic analyzer
NL1000011C2 (nl) * 1995-04-03 1996-10-04 Stichting Scheikundig Onderzoe Werkwijze en inrichting voor het analyseren van de chemische samenstelling van deeltjes.
WO1998041876A1 (en) * 1997-03-17 1998-09-24 Tsi Incorporated System for detecting fluorescing components in aerosols
US6959248B2 (en) * 2001-10-25 2005-10-25 The Regents Of The University Of California Real-time detection method and system for identifying individual aerosol particles
US6777673B2 (en) * 2001-12-28 2004-08-17 Academia Sinica Ion trap mass spectrometer
GB2409036B (en) * 2002-06-24 2006-02-15 Tsi Inc Analysis systems detecting particle size and fluorescence

Also Published As

Publication number Publication date
CY1108708T1 (el) 2014-04-09
CN1296963C (zh) 2007-01-24
KR20030077554A (ko) 2003-10-01
WO2002052246A2 (en) 2002-07-04
AU2002226802A1 (en) 2002-07-08
KR100871938B1 (ko) 2008-12-08
NL1016887C2 (nl) 2002-06-18
JP4145651B2 (ja) 2008-09-03
IL156444A0 (en) 2004-01-04
EP1342256B1 (de) 2008-10-15
US6806464B2 (en) 2004-10-19
CA2431255A1 (en) 2002-07-04
ES2315318T3 (es) 2009-04-01
DK1342256T3 (da) 2009-02-16
EP1342256A2 (de) 2003-09-10
US20040075049A1 (en) 2004-04-22
CA2431255C (en) 2010-07-20
IL156444A (en) 2009-07-20
CN1481575A (zh) 2004-03-10
ATE411611T1 (de) 2008-10-15
JP2004520576A (ja) 2004-07-08
PT1342256E (pt) 2009-01-08
WO2002052246A3 (en) 2003-01-23

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