DK1342256T3 - Fremgangsmåde og anordning til detektering og identifikation af bio-aerosolpartikler i luften - Google Patents

Fremgangsmåde og anordning til detektering og identifikation af bio-aerosolpartikler i luften

Info

Publication number
DK1342256T3
DK1342256T3 DK01995811T DK01995811T DK1342256T3 DK 1342256 T3 DK1342256 T3 DK 1342256T3 DK 01995811 T DK01995811 T DK 01995811T DK 01995811 T DK01995811 T DK 01995811T DK 1342256 T3 DK1342256 T3 DK 1342256T3
Authority
DK
Denmark
Prior art keywords
bioaerosol particles
particles
bioaerosol
detecting
air
Prior art date
Application number
DK01995811T
Other languages
English (en)
Inventor
Michael Anthony Stowers
Arjan Laurens Wuijckhuijse
Johannes Cornelis Marijnissen
Charles Eliza Kientz
Original Assignee
Tno
Univ Delft Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno, Univ Delft Tech filed Critical Tno
Application granted granted Critical
Publication of DK1342256T3 publication Critical patent/DK1342256T3/da

Links

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/10Ion sources; Ion guns
    • H01J49/16Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N15/0205Investigating particle size or size distribution by optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0445Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/40Time-of-flight spectrometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
DK01995811T 2000-12-15 2001-12-14 Fremgangsmåde og anordning til detektering og identifikation af bio-aerosolpartikler i luften DK1342256T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1016887A NL1016887C2 (nl) 2000-12-15 2000-12-15 Werkwijze en inrichting voor het detecteren en identificeren van bio-aÙrosoldeeltjes in de lucht.
PCT/NL2001/000914 WO2002052246A2 (en) 2000-12-15 2001-12-14 Method and device for detecting and identifying bio-aerosol particles in the air

Publications (1)

Publication Number Publication Date
DK1342256T3 true DK1342256T3 (da) 2009-02-16

Family

ID=19772588

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01995811T DK1342256T3 (da) 2000-12-15 2001-12-14 Fremgangsmåde og anordning til detektering og identifikation af bio-aerosolpartikler i luften

Country Status (16)

Country Link
US (1) US6806464B2 (da)
EP (1) EP1342256B1 (da)
JP (1) JP4145651B2 (da)
KR (1) KR100871938B1 (da)
CN (1) CN1296963C (da)
AT (1) ATE411611T1 (da)
AU (1) AU2002226802A1 (da)
CA (1) CA2431255C (da)
CY (1) CY1108708T1 (da)
DE (1) DE60136217D1 (da)
DK (1) DK1342256T3 (da)
ES (1) ES2315318T3 (da)
IL (2) IL156444A0 (da)
NL (1) NL1016887C2 (da)
PT (1) PT1342256E (da)
WO (1) WO2002052246A2 (da)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7260483B2 (en) * 2001-10-25 2007-08-21 The Regents Of The University Of California Real-time detection method and system for identifying individual aerosol particles
US7410805B2 (en) 2003-07-30 2008-08-12 The Boeing Company Aerosol detection system using optical and mass discrimination
JP2007508947A (ja) * 2003-09-19 2007-04-12 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 光軸に沿う光運動量の変化から軸線方向光トラップ力を測定するための光力センサ及び方法
US7800750B2 (en) * 2003-09-19 2010-09-21 The Regents Of The University Of California Optical trap utilizing a reflecting mirror for alignment
CN100434899C (zh) * 2004-04-29 2008-11-19 中国科学院安徽光学精密机械研究所 气溶胶粒谱(质谱)飞行时间检测方法及装置
US7837937B2 (en) 2004-07-09 2010-11-23 Hamilton Sundstrand Corporation Biological agent detector
US20090084979A1 (en) * 2004-10-07 2009-04-02 Dewalch Norman Binz High-speed molecular analyzer system and method
US20090218481A1 (en) * 2004-10-07 2009-09-03 Dewalch Norman Binz High-Speed Molecular Analyzer System and Method
DE102004061820A1 (de) * 2004-12-22 2006-07-06 Bruker Daltonik Gmbh Lasersystem für die lonisation durch matrixunterstützte Laserdesorption (MALDI) im ultravioletten Spektralbereich (UV)
DE102005005333B4 (de) * 2005-01-28 2008-07-31 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren zur Probennahme und Aerosol-Analyse
US7981365B2 (en) * 2005-09-15 2011-07-19 The United States Of America As Represented By The Secretary Of The Navy Electrospray coating of aerosols for labeling and identification
US7343782B2 (en) * 2006-04-10 2008-03-18 Northrop Grumman Corporation System and method for performing quantifiable release spore testing on bioaerosol detection technologies
WO2008079407A1 (en) * 2006-12-26 2008-07-03 Brigham Young University Serum proteomics system and associated methods
EP2060919A1 (en) * 2007-11-13 2009-05-20 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO MALDI matrix and MALDI method
US8031339B2 (en) * 2007-12-21 2011-10-04 Lawrence Livermore National Security, Llc Particle measurement systems and methods
US8513598B2 (en) * 2007-12-21 2013-08-20 Lawrence Livermore National Security, Llc Aerosol mass spectrometry systems and methods
EP2157599A1 (en) 2008-08-21 2010-02-24 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Method and apparatus for identification of biological material
WO2010080643A1 (en) * 2008-12-18 2010-07-15 Biovigilant Systems, Inc. Integrated microbial collector
CN101581698B (zh) * 2009-06-23 2012-08-22 中国科学院安徽光学精密机械研究所 气溶胶场致电离电荷源装置
US8625091B2 (en) * 2009-09-30 2014-01-07 Genia Photonics Inc. Spectrometer
KR101235145B1 (ko) * 2011-06-21 2013-02-20 광주과학기술원 연속파 레이저 및 광전증배관을 이용하는 분광분석장치
KR101523658B1 (ko) * 2014-12-04 2015-05-29 국방과학연구소 형광 에어로졸을 이용한 필터류의 입자 투과 성능 평가 시험 방법 및 장치
EP3341111B1 (en) * 2015-08-24 2020-09-30 Zeteo Tech, Inc. Coating of aerosol particles using an acoustic coater
KR101787579B1 (ko) 2016-03-31 2017-10-19 주식회사 아스타 근적외선 형광을 이용한 질량 분석 장치 및 방법
CN106248777A (zh) * 2016-08-18 2016-12-21 东南大学 一种常压敞开式进样系统
CN106442449A (zh) * 2016-10-17 2017-02-22 中国科学院合肥物质科学研究院 一种激光诱导荧光探测生物气溶胶装置
NL2018940B1 (en) 2017-05-18 2018-11-28 Biosparq B V Maldi mass spectrometry method
CN107389627B (zh) * 2017-05-26 2020-04-03 清华大学 一种单液滴单细胞培养和细胞代谢产物实时检测装置
CN107841453A (zh) * 2017-11-02 2018-03-27 广州禾信仪器股份有限公司 微生物收集装置及收集检测方法
US11662280B2 (en) 2017-12-29 2023-05-30 The Regents Of The University Of Colorado, A Body Corporate Hi-fidelity bioaerosol condensation capture directly into genomic preservatives
US20210082676A1 (en) * 2018-06-04 2021-03-18 Dh Technologies Development Pte. Ltd. LBMFI Detector for Fluorophore Labeled Analytes at the Taylor Cone in ESI-MS
US11808688B2 (en) * 2018-10-25 2023-11-07 Plair, SA Method and device for detection and/or measurement of impurities in droplets
RU2722066C2 (ru) * 2018-11-19 2020-05-26 Самсунг Электроникс Ко., Лтд. Многоканальный датчик пыли
KR102201084B1 (ko) * 2019-01-21 2021-01-11 연세대학교 산학협력단 황사탐지인자(tdci)를 이용한 에어로졸 유형 분석 시스템
CN110018090B (zh) * 2019-05-17 2020-10-27 中国科学院化学研究所 一种颗粒物化学组分测量系统及方法
WO2021061247A2 (en) * 2019-06-29 2021-04-01 Zeteo Tech, Inc. Methods and systems for detecting aerosol particles without using complex organic maldi matrices
KR102100774B1 (ko) * 2019-10-15 2020-04-14 광주과학기술원 초미세입자의 크기-성분 측정 장치 및 크기-성분 측정 방법
NL2027583B1 (en) 2021-02-18 2022-09-15 Deem Consulting B V A time-of-flight mass spectrometer device
CN114459965A (zh) * 2021-12-30 2022-05-10 中船重工安谱(湖北)仪器有限公司 一种气溶胶监测系统及方法
KR102506969B1 (ko) 2023-02-05 2023-03-06 김인영 실내공기 중의 바이오 에어로졸을 신속하게 검출하는 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4383171A (en) * 1980-11-17 1983-05-10 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Particle analyzing method and apparatus
DE3517667A1 (de) * 1985-05-15 1986-11-20 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Laser-massenspektrometer
GB2177507B (en) * 1985-06-13 1989-02-15 Mitsubishi Electric Corp Laser mass spectroscopic analyzer
NL1000011C2 (nl) * 1995-04-03 1996-10-04 Stichting Scheikundig Onderzoe Werkwijze en inrichting voor het analyseren van de chemische samenstelling van deeltjes.
US5999250A (en) * 1997-03-17 1999-12-07 Tsi Corporation System for detecting fluorescing components in aerosols
US6959248B2 (en) * 2001-10-25 2005-10-25 The Regents Of The University Of California Real-time detection method and system for identifying individual aerosol particles
US6777673B2 (en) * 2001-12-28 2004-08-17 Academia Sinica Ion trap mass spectrometer
WO2004001382A2 (en) * 2002-06-24 2003-12-31 Tsi Incorporated Analysis systems detecting particle size and fluorescence

Also Published As

Publication number Publication date
IL156444A (en) 2009-07-20
ES2315318T3 (es) 2009-04-01
EP1342256B1 (en) 2008-10-15
KR100871938B1 (ko) 2008-12-08
WO2002052246A3 (en) 2003-01-23
IL156444A0 (en) 2004-01-04
DE60136217D1 (de) 2008-11-27
JP2004520576A (ja) 2004-07-08
CN1296963C (zh) 2007-01-24
CY1108708T1 (el) 2014-04-09
PT1342256E (pt) 2009-01-08
KR20030077554A (ko) 2003-10-01
CN1481575A (zh) 2004-03-10
NL1016887C2 (nl) 2002-06-18
AU2002226802A1 (en) 2002-07-08
CA2431255A1 (en) 2002-07-04
CA2431255C (en) 2010-07-20
EP1342256A2 (en) 2003-09-10
ATE411611T1 (de) 2008-10-15
US6806464B2 (en) 2004-10-19
JP4145651B2 (ja) 2008-09-03
WO2002052246A2 (en) 2002-07-04
US20040075049A1 (en) 2004-04-22

Similar Documents

Publication Publication Date Title
DK1342256T3 (da) Fremgangsmåde og anordning til detektering og identifikation af bio-aerosolpartikler i luften
US7816644B2 (en) Photoactivated collision induced dissociation (PACID) (apparatus and method)
US6797943B2 (en) Method and apparatus for ion mobility spectrometry
US20070046934A1 (en) Multi-function laser induced breakdown spectroscopy and laser ablation material analysis system and method
US20130306855A1 (en) Efficient detection of ion species utilizing fluorescence and optics
Northway et al. Demonstration of a VUV lamp photoionization source for improved organic speciation in an aerosol mass spectrometer
CN108695135A (zh) 用于从气溶胶颗粒生成元素离子的离子源和方法
JP2020507883A5 (da)
DK1266396T3 (da) Fremgangsmåde og indretning til detektion af forbindelser i en gasström
CA2381070A1 (en) Detector of chemical substances and concentration-measuring method of chemical substances
JPH08240566A (ja) レーザ支援による粒子分析
EP2107594A3 (en) Apparatus and method for detecting organic trace components
Gaie-Levrel et al. Development and characterization of a single particle laser ablation mass spectrometer (SPLAM) for organic aerosol studies
KR101319925B1 (ko) 자외선 다이오드와 cem을 이용한 질량분석기의 이온화원 획득장치
CN103500696B (zh) 具有多次反射真空紫外光电离源的质谱分析仪
JP2007309879A (ja) 質量分析計
CN203466164U (zh) 具有多次反射真空紫外光电离源的质谱分析仪
CN112074927A (zh) 用于粒子的质谱分析的装置和方法
JP2007309878A (ja) 質量分析計
JPH1137974A (ja) 粒子組成分析装置
JPS6066155A (ja) 光吸収イオン化検出器
JP2004061350A (ja) 極微量イオン検出装置
Osorio et al. Time-of-flight mass spectroscopy measurements of TNT and RDX on soil surfaces
JP2687433B2 (ja) 質量分析計
Trimborn et al. Development of Soft Ionization for Particulate Organic Detection with the Aerodyne Aerosol Mass Spectrometer