DE60128120T2 - Saururus chinensis-extrakt zur prophylaxis und behandlung neurodegenerativer krankheiten - Google Patents

Saururus chinensis-extrakt zur prophylaxis und behandlung neurodegenerativer krankheiten Download PDF

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Publication number
DE60128120T2
DE60128120T2 DE60128120T DE60128120T DE60128120T2 DE 60128120 T2 DE60128120 T2 DE 60128120T2 DE 60128120 T DE60128120 T DE 60128120T DE 60128120 T DE60128120 T DE 60128120T DE 60128120 T2 DE60128120 T2 DE 60128120T2
Authority
DE
Germany
Prior art keywords
glutamate
treatment
cells
aristolactam
saurolactam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60128120T
Other languages
German (de)
English (en)
Other versions
DE60128120D1 (de
Inventor
Young-Joong Gwangjin-gu KIM
Sang-Hyun Sung
So-Ra Gwanak-gu KIM
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elcom Bio Technology Co Ltd
Original Assignee
Elcom Bio Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR10-2000-0061687A external-priority patent/KR100446089B1/ko
Priority claimed from KR10-2000-0061688A external-priority patent/KR100446090B1/ko
Application filed by Elcom Bio Technology Co Ltd filed Critical Elcom Bio Technology Co Ltd
Publication of DE60128120D1 publication Critical patent/DE60128120D1/de
Application granted granted Critical
Publication of DE60128120T2 publication Critical patent/DE60128120T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
DE60128120T 2000-10-19 2001-10-19 Saururus chinensis-extrakt zur prophylaxis und behandlung neurodegenerativer krankheiten Expired - Lifetime DE60128120T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR2000061688 2000-10-19
KR2000061687 2000-10-19
KR10-2000-0061687A KR100446089B1 (ko) 2000-10-19 2000-10-19 퇴행성 뇌신경계 질환 예방 또는 치료 효과를 갖는 삼백초 추출물 및 이 추출물을 활성성분으로 함유하는 약학적 제제
KR10-2000-0061688A KR100446090B1 (ko) 2000-10-19 2000-10-19 사우로락탐계 알카로이드의 퇴행성 뇌신경계 질환의 예방과 치료제로서의 용도 및 이 화합물을 유효성분으로 함유하는 약학적 제제
PCT/KR2001/001766 WO2002032443A1 (en) 2000-10-19 2001-10-19 Saururus chinensis extract for prevention and treatment of neurodegenerative disease

Publications (2)

Publication Number Publication Date
DE60128120D1 DE60128120D1 (de) 2007-06-06
DE60128120T2 true DE60128120T2 (de) 2008-01-10

Family

ID=26638479

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60128120T Expired - Lifetime DE60128120T2 (de) 2000-10-19 2001-10-19 Saururus chinensis-extrakt zur prophylaxis und behandlung neurodegenerativer krankheiten

Country Status (8)

Country Link
US (1) US20030045564A1 (zh)
EP (1) EP1326623B1 (zh)
JP (1) JP4157767B2 (zh)
CN (1) CN1245983C (zh)
AT (1) ATE360431T1 (zh)
AU (1) AU2002212774A1 (zh)
DE (1) DE60128120T2 (zh)
WO (1) WO2002032443A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080260873A1 (en) * 2007-04-23 2008-10-23 Fancl Corporation Agent for prevention or improvement of neuropathy comprising pre-germinated brown rice lipid fraction as an effective ingredient
KR101124350B1 (ko) * 2007-10-17 2012-03-15 한국화학연구원 항암 활성을 갖는 페난트렌 락탐 유도체, 이의 제조방법 및이를 포함하는 약학 조성물
WO2018111050A1 (ko) * 2016-12-15 2018-06-21 한국생명공학연구원 페난트란-락탐계 화합물을 유효성분으로 함유하는 dyrk 관련 질환의 예방 또는 치료용 약학적 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619943A (en) * 1981-06-04 1986-10-28 Rao Koppaka V Neolignans of Saururus cernuus L and analogues thereof
US4782077A (en) * 1987-08-20 1988-11-01 Monoclonetics International, Inc. Taliscanin and other aristolactams for treating neurological disorders, Parkinson's disease, Alzheimer disease and impotence
JP4014177B2 (ja) * 1997-03-10 2007-11-28 株式会社資生堂 プロテアーゼ阻害剤
KR100380634B1 (ko) * 2000-10-19 2003-04-26 주식회사 엘컴사이언스 디벤조사이클로옥탄계 리그난 화합물을 포함하는 퇴행성 뇌신경계 질환의 예방 또는 치료용 조성물

Also Published As

Publication number Publication date
AU2002212774A1 (en) 2002-04-29
US20030045564A1 (en) 2003-03-06
WO2002032443A1 (en) 2002-04-25
ATE360431T1 (de) 2007-05-15
EP1326623B1 (en) 2007-04-25
JP4157767B2 (ja) 2008-10-01
EP1326623A1 (en) 2003-07-16
JP2004511525A (ja) 2004-04-15
DE60128120D1 (de) 2007-06-06
CN1245983C (zh) 2006-03-22
CN1394143A (zh) 2003-01-29
EP1326623A4 (en) 2004-06-09

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