DE60127407D1 - Hochwirksame verabreichung eines aerosols mit hoher therapeutischer masse - Google Patents

Hochwirksame verabreichung eines aerosols mit hoher therapeutischer masse

Info

Publication number
DE60127407D1
DE60127407D1 DE60127407T DE60127407T DE60127407D1 DE 60127407 D1 DE60127407 D1 DE 60127407D1 DE 60127407 T DE60127407 T DE 60127407T DE 60127407 T DE60127407 T DE 60127407T DE 60127407 D1 DE60127407 D1 DE 60127407D1
Authority
DE
Germany
Prior art keywords
particles
agent
mass
aerosol
delivering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE60127407T
Other languages
English (en)
Other versions
DE60127407T2 (de
Inventor
David A Edwards
Richard P Batycky
Lloyd Johnston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alkermes Inc
Original Assignee
Advanced Inhalation Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24365965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60127407(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Advanced Inhalation Research Inc filed Critical Advanced Inhalation Research Inc
Application granted granted Critical
Publication of DE60127407D1 publication Critical patent/DE60127407D1/de
Publication of DE60127407T2 publication Critical patent/DE60127407T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60127407T 2000-06-09 2001-06-08 Hochwirksame verabreichung eines aerosols mit hoher therapeutischer masse Revoked DE60127407T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/591,307 US6858199B1 (en) 2000-06-09 2000-06-09 High efficient delivery of a large therapeutic mass aerosol
US591307 2000-06-09
PCT/US2001/018491 WO2001095874A2 (en) 2000-06-09 2001-06-08 Highly efficient delivery of a large therapeutic mass aerosol

Publications (2)

Publication Number Publication Date
DE60127407D1 true DE60127407D1 (de) 2007-05-03
DE60127407T2 DE60127407T2 (de) 2007-11-29

Family

ID=24365965

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60127407T Revoked DE60127407T2 (de) 2000-06-09 2001-06-08 Hochwirksame verabreichung eines aerosols mit hoher therapeutischer masse

Country Status (21)

Country Link
US (6) US6858199B1 (de)
EP (2) EP1296663B1 (de)
JP (2) JP2004503482A (de)
KR (1) KR100697479B1 (de)
CN (1) CN100589796C (de)
AT (1) ATE357222T1 (de)
AU (2) AU2001275368B2 (de)
CA (1) CA2412561C (de)
DE (1) DE60127407T2 (de)
DK (1) DK1296663T3 (de)
ES (1) ES2283417T3 (de)
HK (1) HK1051139A1 (de)
IL (1) IL153281A0 (de)
MX (1) MXPA02012023A (de)
NO (1) NO20025873L (de)
NZ (1) NZ523254A (de)
PL (1) PL360287A1 (de)
PT (1) PT1296663E (de)
RU (1) RU2275900C2 (de)
SI (1) SI1296663T1 (de)
WO (1) WO2001095874A2 (de)

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NZ523254A (en) 2004-07-30
ATE357222T1 (de) 2007-04-15
EP1767196A3 (de) 2009-02-25
US7556798B2 (en) 2009-07-07
NO20025873L (no) 2003-02-06
CA2412561C (en) 2009-05-12
US6858199B1 (en) 2005-02-22
JP2009019047A (ja) 2009-01-29
WO2001095874A3 (en) 2003-01-16
EP1296663B1 (de) 2007-03-21
EP1767196A2 (de) 2007-03-28
US6921528B2 (en) 2005-07-26
RU2275900C2 (ru) 2006-05-10
CN1441670A (zh) 2003-09-10
MXPA02012023A (es) 2004-08-19
PT1296663E (pt) 2007-06-22
US20020035993A1 (en) 2002-03-28
IL153281A0 (en) 2003-07-06
JP2004503482A (ja) 2004-02-05
NO20025873D0 (no) 2002-12-06
EP1296663A2 (de) 2003-04-02
HK1051139A1 (en) 2003-07-25
US20090068274A1 (en) 2009-03-12
US20040076589A1 (en) 2004-04-22
CA2412561A1 (en) 2001-12-20
DE60127407T2 (de) 2007-11-29
CN100589796C (zh) 2010-02-17
WO2001095874A2 (en) 2001-12-20
US20120093893A1 (en) 2012-04-19
DK1296663T3 (da) 2007-07-30
AU2001275368B2 (en) 2005-10-20
US20140178476A1 (en) 2014-06-26
SI1296663T1 (sl) 2007-08-31
KR20030063117A (ko) 2003-07-28
AU7536801A (en) 2001-12-24
PL360287A1 (en) 2004-09-06
ES2283417T3 (es) 2007-11-01
KR100697479B1 (ko) 2007-03-20
US8628754B2 (en) 2014-01-14

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