DE60108799D1 - Fluoreszente Nucleotide, enthaltend einen Cyanin, Merocyanin- oder Styryl-Farbstoff, zur Erkennung von Nucleinsäuren - Google Patents

Fluoreszente Nucleotide, enthaltend einen Cyanin, Merocyanin- oder Styryl-Farbstoff, zur Erkennung von Nucleinsäuren

Info

Publication number
DE60108799D1
DE60108799D1 DE60108799T DE60108799T DE60108799D1 DE 60108799 D1 DE60108799 D1 DE 60108799D1 DE 60108799 T DE60108799 T DE 60108799T DE 60108799 T DE60108799 T DE 60108799T DE 60108799 D1 DE60108799 D1 DE 60108799D1
Authority
DE
Germany
Prior art keywords
merocyanine
cyanine
recognition
nucleic acids
nucleotides containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60108799T
Other languages
English (en)
Other versions
DE60108799T2 (de
Inventor
Hiroshi Shinoki
Hiroko Inomata
Masayoshi Kojima
Yukio Sudo
Osamu Seshimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Corp
Original Assignee
Fuji Photo Film Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fuji Photo Film Co Ltd filed Critical Fuji Photo Film Co Ltd
Application granted granted Critical
Publication of DE60108799D1 publication Critical patent/DE60108799D1/de
Publication of DE60108799T2 publication Critical patent/DE60108799T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
DE60108799T 2000-04-10 2001-04-10 Fluoreszente Nucleotide, enthaltend einen Cyanin, Merocyanin- oder Styryl-Farbstoff, zur Erkennung von Nucleinsäuren Expired - Lifetime DE60108799T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000107675A JP2001288197A (ja) 2000-04-10 2000-04-10 蛍光ヌクレオチド
JP2000107675 2000-04-10

Publications (2)

Publication Number Publication Date
DE60108799D1 true DE60108799D1 (de) 2005-03-17
DE60108799T2 DE60108799T2 (de) 2006-04-27

Family

ID=18620635

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60108799T Expired - Lifetime DE60108799T2 (de) 2000-04-10 2001-04-10 Fluoreszente Nucleotide, enthaltend einen Cyanin, Merocyanin- oder Styryl-Farbstoff, zur Erkennung von Nucleinsäuren

Country Status (4)

Country Link
US (1) US7109314B2 (de)
EP (1) EP1152008B1 (de)
JP (1) JP2001288197A (de)
DE (1) DE60108799T2 (de)

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JP2003261464A (ja) * 2002-03-07 2003-09-16 Fuji Photo Film Co Ltd 近赤外蛍光造影剤および蛍光造影法
US20040175717A1 (en) * 2002-06-20 2004-09-09 North Carolina State University Methods and kits for labeling and hybridizing cDNA for microarray analysis
US7662555B2 (en) 2003-12-24 2010-02-16 Shinichiro Isobe Method for detecting biomolecule, labeling dye used therefore, and labeling kit
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JP2008501679A (ja) * 2004-06-02 2008-01-24 エーエスエム サイエンティフィック， インコーポレイテッド ２’−ニトロベンジル改変型リボヌクレオチド
GB2434150B (en) * 2005-04-22 2009-10-14 Ge Healthcare Uk Ltd Fluoro-substituted 2-methyl indolinium precursors of reactive fluorescence labelling water-soluble cyanine dyes
US7939613B2 (en) * 2005-04-22 2011-05-10 The Hong Kong University Of Science And Technology Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same
CN101273096B (zh) * 2005-07-28 2014-08-13 礒部信一郎 生物分子用标记色素、标记试剂盒以及生物分子的检测方法
TWI334232B (en) * 2005-10-13 2010-12-01 Tube Smith Technology Co Ltd Blue-laser-adsorbing material
ITSV20060002A1 (it) 2006-01-19 2007-07-20 Ferrania Technologies Spa Colorante fluorescente di tipo cianinico
JP4621926B2 (ja) * 2008-07-24 2011-02-02 国立大学法人九州大学 酵素基質修飾ヌクレオシド三リン酸、核酸プローブ、マルチラベル化核酸プローブ、マルチラベル化核酸プローブの製造方法および標的核酸の検出方法
JP5146785B2 (ja) * 2008-07-24 2013-02-20 国立大学法人九州大学 酵素基質修飾ヌクレオシド三リン酸誘導体
JP5704481B2 (ja) * 2010-01-22 2015-04-22 国立大学法人九州大学 核酸検出用キット
US10053447B2 (en) 2010-12-21 2018-08-21 Pierce Biotechnology, Inc Fluorescent compounds
US8889884B1 (en) 2011-07-14 2014-11-18 Pierce Biotechnology, Inc. Phosphine derivatives of fluorescent compounds
US9249307B2 (en) 2011-08-16 2016-02-02 Pierce Biotechnology, Inc. Benzocyanine compounds
US9751868B2 (en) 2012-02-28 2017-09-05 Pierce Biotechnology, Inc. Benzocyanine compounds
US20140072515A9 (en) 2012-03-02 2014-03-13 Greg Hermanson Cyanine compounds
CN104540819B (zh) 2012-08-28 2019-04-19 皮尔斯生物科技有限公司 苯并吡喃鎓化合物
GB201408077D0 (en) 2014-05-07 2014-06-18 Illumina Cambridge Ltd Polymethine compounds and their use as fluorescent labels
KR101880502B1 (ko) * 2016-04-20 2018-08-20 에스에프씨 주식회사 메로시아닌계 화합물, 이를 포함하는 생체분자 표지용 염료, 키트 및 조영제 조성물
RU2637310C1 (ru) * 2016-06-08 2017-12-04 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Флуоресцентно-меченые дезоксиуридинтрифосфаты
WO2019078513A1 (ko) 2017-10-17 2019-04-25 에스에프씨 주식회사 메로시아닌계 화합물, 이를 포함하는 생체분자 표지용 염료, 키트 및 조영제 조성물
RU2725884C2 (ru) * 2017-11-21 2020-07-07 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Дезоксиуридинтрифосфаты, маркированные цвитерионными индоцианиновыми красителями
CN113039191B (zh) 2018-10-25 2024-07-16 奇异基因组学系统公司 核苷酸类似物
EP4117682A4 (de) * 2020-04-24 2023-09-13 Singular Genomics Systems, Inc. Modifizierte nukleotide und verwendungen davon
EP4444320A2 (de) 2021-12-10 2024-10-16 Singular Genomics Systems, Inc. Spaltbare disulfidlinker und verwendungen davon

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US5569587A (en) * 1986-04-18 1996-10-29 Carnegie Mellon University Method for labeling and detecting materials employing luminescent arysulfonate cyanine dyes
US5268486A (en) * 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
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DE3912046B4 (de) * 1988-09-02 2004-03-25 Carnegie Mellon University Verfahren zum Markieren einer Komponente einer wäßrigen Flüssigkeit und lumineszenzphotostabiles Reaktionsprodukt
JP3011817B2 (ja) * 1992-04-09 2000-02-21 富士写真フイルム株式会社 メチン化合物
JPH07145148A (ja) * 1992-06-02 1995-06-06 Bio Sensor Kenkyusho:Kk ポリメチン系化合物およびそれを用いる測定方法
US5808044A (en) * 1993-01-22 1998-09-15 Pharmacia Biotech Inc. Indocarbocyanine and benzindocarbocyanine phosphoramidites
JP3176163B2 (ja) * 1993-01-28 2001-06-11 イビデン株式会社 蛍光標識試薬および蛍光免疫測定法
JP3260884B2 (ja) * 1993-02-05 2002-02-25 キヤノン株式会社 標識複合体、それを用いる分析法、生体関連物質の検出および定量の方法
JP3466662B2 (ja) * 1993-07-08 2003-11-17 キヤノン株式会社 色素標識化核酸プローブの製造方法及び該核酸プローブ形成用中間体
JP3368011B2 (ja) * 1993-10-04 2003-01-20 キヤノン株式会社 核酸検出法
US5808043A (en) * 1995-01-18 1998-09-15 Pharmacia Biotech Inc. Composition for stabilization of labelled nucleoside triphosphates and methods for using same
JP3669752B2 (ja) * 1995-01-30 2005-07-13 第一化学薬品株式会社 診断用マーカー
JP4098839B2 (ja) * 1995-01-30 2008-06-11 株式会社同仁化学研究所 インドシアニン化合物
US5986093A (en) * 1995-06-07 1999-11-16 Carnegie Mellon University Monomethine cyanines rigidized by a two-carbon chain
US5719031A (en) * 1996-08-14 1998-02-17 Molecular Probes, Inc. Dye labeled polymers as reagents for measuring polymer degradation
US6027709A (en) * 1997-01-10 2000-02-22 Li-Cor Inc. Fluorescent cyanine dyes
US5986086A (en) * 1997-06-20 1999-11-16 Amersham Pharmacia Biotech Inc. Non-sulfonated cyanine dyes for labeling nucleosides and nucleotides
US6130101A (en) * 1997-09-23 2000-10-10 Molecular Probes, Inc. Sulfonated xanthene derivatives
EP1065250B1 (de) * 1999-07-02 2004-12-08 Visen Medical, Inc. Fluorescierende Cyaninlabels mit einem Sulphamidobrückenglied

Also Published As

Publication number Publication date
EP1152008B1 (de) 2005-02-09
DE60108799T2 (de) 2006-04-27
EP1152008A3 (de) 2002-03-20
US7109314B2 (en) 2006-09-19
JP2001288197A (ja) 2001-10-16
EP1152008A2 (de) 2001-11-07
US20020064782A1 (en) 2002-05-30

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Legal Events

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Owner name: FUJIFILM CORP., TOKIO/TOKYO, JP