DE60100433D1 - Proteinbeschichtung - Google Patents
ProteinbeschichtungInfo
- Publication number
- DE60100433D1 DE60100433D1 DE60100433T DE60100433T DE60100433D1 DE 60100433 D1 DE60100433 D1 DE 60100433D1 DE 60100433 T DE60100433 T DE 60100433T DE 60100433 T DE60100433 T DE 60100433T DE 60100433 D1 DE60100433 D1 DE 60100433D1
- Authority
- DE
- Germany
- Prior art keywords
- implant
- coating
- solution
- submersing
- magnesium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000011248 coating agent Substances 0.000 title abstract 4
- 238000000576 coating method Methods 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 239000007943 implant Substances 0.000 abstract 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 2
- 229910052791 calcium Inorganic materials 0.000 abstract 2
- 239000011575 calcium Substances 0.000 abstract 2
- 229910052749 magnesium Inorganic materials 0.000 abstract 2
- 239000011777 magnesium Substances 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000007872 degassing Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/082—Inorganic materials
- A61L31/086—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00200393 | 2000-02-04 | ||
EP00200393 | 2000-02-04 | ||
PCT/NL2001/000071 WO2001056628A1 (en) | 2000-02-04 | 2001-02-01 | Proteinaceous coating |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60100433D1 true DE60100433D1 (de) | 2003-08-07 |
DE60100433T2 DE60100433T2 (de) | 2004-04-15 |
Family
ID=8170984
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60100433T Expired - Lifetime DE60100433T2 (de) | 2000-02-04 | 2001-02-01 | Proteinbeschichtung |
Country Status (9)
Country | Link |
---|---|
US (1) | US6692790B2 (de) |
EP (1) | EP1251889B1 (de) |
JP (1) | JP2003521351A (de) |
AT (1) | ATE244027T1 (de) |
AU (1) | AU2001237786A1 (de) |
CA (1) | CA2399216A1 (de) |
DE (1) | DE60100433T2 (de) |
ES (1) | ES2206407T3 (de) |
WO (1) | WO2001056628A1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002059395A2 (en) | 2000-12-28 | 2002-08-01 | The Board Of Regents Of The University Of Nebraska | Electrolytic deposition of coatings for prosthetic metals and alloys |
DE10119096A1 (de) * | 2001-04-19 | 2002-10-24 | Keramed Medizintechnik Gmbh | Biologisch funktionalisierte, metabolisch induktive Implantatoberflächen |
ATE303169T1 (de) † | 2001-11-19 | 2005-09-15 | Scil Technology Gmbh | Homogen beschichtete vorrichtung mit osteoinduktiven und osteokonduktiven eigenschaften |
WO2003070749A2 (en) | 2002-02-15 | 2003-08-28 | Northwestern University | Self-assembly of peptide-amphiphile nanofibers under physiological conditions |
DE10230720A1 (de) * | 2002-07-08 | 2004-02-12 | Tinox Ag I.Ins. | Implantat |
US6749429B1 (en) * | 2002-09-10 | 2004-06-15 | William J. Haraden | Matrix band for use in dentistry |
US7554021B2 (en) | 2002-11-12 | 2009-06-30 | Northwestern University | Composition and method for self-assembly and mineralization of peptide amphiphiles |
JP4478754B2 (ja) * | 2002-11-25 | 2010-06-09 | 独立行政法人産業技術総合研究所 | タンパク質担持リン酸カルシウム、その製造方法及びそれを用いたタンパク質徐放体、人工骨及び組織工学スキャフォールド |
US7087086B2 (en) * | 2003-01-31 | 2006-08-08 | Depuy Products, Inc. | Biological agent-containing ceramic coating and method |
CA2515651A1 (en) * | 2003-02-11 | 2004-08-26 | Northwestern University | Methods and materials for nanocrystalline surface coatings and attachment of peptide amphiphile nanofibers thereon |
JP4472267B2 (ja) * | 2003-05-02 | 2010-06-02 | 株式会社ジーシー | 骨結合を得るためのチタン製インプラント及びその表面処理方法 |
US8251700B2 (en) † | 2003-05-16 | 2012-08-28 | Biomet 3I, Llc | Surface treatment process for implants made of titanium alloy |
AU2004296181A1 (en) | 2003-12-05 | 2005-06-23 | Northwestern University | Self-assembling peptide amphiphiles and related methods for growth factor delivery |
EP1737734B1 (de) | 2004-03-10 | 2010-08-18 | Scil Technology GmbH | Überzogene implantate, ihre herstellung und verwendung davon |
US20080241353A1 (en) * | 2004-08-10 | 2008-10-02 | Yekimed Ag | Biomimetic Process For Coating Substrates With A Biomimetic Solution Containing A Bioactive Substance And Use Of Said Process And Substrates In Bone, Connective Tissue-, Fat Tissue-And Muscle Tissue Engineering |
US20060039949A1 (en) * | 2004-08-20 | 2006-02-23 | Nycz Jeffrey H | Acetabular cup with controlled release of an osteoinductive formulation |
JP2006325467A (ja) * | 2005-05-25 | 2006-12-07 | Pentax Corp | コラーゲン被覆担体およびコラーゲン被覆担体の製造方法 |
US20090053391A1 (en) * | 2005-12-06 | 2009-02-26 | Ludwig Florian N | Method Of Coating A Drug-Releasing Layer Onto A Substrate |
US8069814B2 (en) | 2006-05-04 | 2011-12-06 | Advanced Cardiovascular Systems, Inc. | Stent support devices |
US20080097618A1 (en) * | 2006-10-18 | 2008-04-24 | Kevin Charles Baker | Deposition of calcium-phosphate (CaP) and calcium-phosphate with bone morphogenic protein (CaP+BMP) coatings on metallic and polymeric surfaces |
US20080233203A1 (en) * | 2007-03-21 | 2008-09-25 | Jennifer Woodell-May | Porous orthapedic materials coated with demineralized bone matrix |
US8076295B2 (en) | 2007-04-17 | 2011-12-13 | Nanotope, Inc. | Peptide amphiphiles having improved solubility and methods of using same |
US8133553B2 (en) | 2007-06-18 | 2012-03-13 | Zimmer, Inc. | Process for forming a ceramic layer |
US8309521B2 (en) | 2007-06-19 | 2012-11-13 | Zimmer, Inc. | Spacer with a coating thereon for use with an implant device |
US8039038B2 (en) * | 2007-08-20 | 2011-10-18 | Council Of Scientific And Industrial Research | Process for the preparation of protein mediated calcium hydroxyapatite (HAp) coating on metal substrate |
US20110230973A1 (en) * | 2007-10-10 | 2011-09-22 | Zimmer, Inc. | Method for bonding a tantalum structure to a cobalt-alloy substrate |
US8608049B2 (en) * | 2007-10-10 | 2013-12-17 | Zimmer, Inc. | Method for bonding a tantalum structure to a cobalt-alloy substrate |
US20090187256A1 (en) * | 2008-01-21 | 2009-07-23 | Zimmer, Inc. | Method for forming an integral porous region in a cast implant |
US20090198286A1 (en) * | 2008-02-05 | 2009-08-06 | Zimmer, Inc. | Bone fracture fixation system |
JP2012523463A (ja) | 2009-04-13 | 2012-10-04 | ノースウエスタン ユニバーシティ | 軟骨再生のための新規なペプチドベースの足場およびその使用方法 |
WO2010138062A1 (en) * | 2009-05-28 | 2010-12-02 | Addbio Ab | Multilayer protein films, methods of making, and drug delivery devices and biomedical implants employing the films |
KR101286721B1 (ko) * | 2009-06-05 | 2013-07-16 | 한국과학기술연구원 | 폴리-시스테인 펩티드 융합 재조합 알부민 및 이의 제조방법 |
CA2908536C (en) * | 2009-09-04 | 2018-03-20 | The Proctor & Gamble Company | Apparatus and methods for visual demonstration of dental erosion on simulated dental materials |
US20110076396A1 (en) * | 2009-09-28 | 2011-03-31 | Limin Guan | Method of forming a calcium phosphate coating within a porous material |
UA104738C2 (ru) * | 2011-05-18 | 2014-03-11 | Олег Миколайович Лазаренко | Композиция для повышения биосовместимости имплантатов и клеток для трансплантации с организмом реципиента и способ ее приготовления |
CN104013997B (zh) * | 2014-05-06 | 2016-01-20 | 重庆大学 | 一种具有生物仿生多层结构界面的医用钛合金制备方法 |
CN104667350B (zh) * | 2015-03-12 | 2017-03-29 | 南京医科大学第一附属医院 | 三层一体化复合支架及其制作方法 |
CN115137875B (zh) * | 2021-03-29 | 2023-06-13 | 杭州彗搏科技有限公司 | 一种高效的双相磷酸钙涂层方法 |
CN113230453A (zh) * | 2021-05-06 | 2021-08-10 | 长兴盛隆科技有限公司 | 一种医用镁合金耐腐蚀涂层的制备方法 |
CN114890400B (zh) * | 2022-06-15 | 2023-12-01 | 杭州彗搏科技有限公司 | 纳米晶体羟基磷灰石骨修复颗粒、制备方法及应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3414924A1 (de) * | 1984-04-19 | 1985-10-31 | Klaus Dr.med. Dr.med.habil. 8000 München Draenert | Beschichtetes verankerungsteil fuer implantate |
NL9301941A (nl) * | 1993-11-09 | 1995-06-01 | Klaas De Groot | Werkwijze voor het aanbrengen van een bekleding van een bioactief materiaal op implantaten. |
IT1288038B1 (it) * | 1996-04-30 | 1998-09-10 | Flametal S P A | Procedimento per la preparazione di rivestimenti di idrossiapatite |
EP0806212B1 (de) * | 1996-05-10 | 2003-04-02 | IsoTis N.V. | Vorrichtung zur Aufnahme und Freigabe von biologisch aktiven Substanzen |
WO1999011202A1 (en) * | 1997-09-05 | 1999-03-11 | Icet, Inc. | Biomimetic calcium phosphate implant coatings and methods for making the same |
US6139585A (en) * | 1998-03-11 | 2000-10-31 | Depuy Orthopaedics, Inc. | Bioactive ceramic coating and method |
ES2196717T3 (es) | 1998-09-15 | 2003-12-16 | Isotis Nv | Metodo para el recubrimiento de materiales de implantes medicos. |
-
2001
- 2001-02-01 ES ES01910206T patent/ES2206407T3/es not_active Expired - Lifetime
- 2001-02-01 AT AT01910206T patent/ATE244027T1/de not_active IP Right Cessation
- 2001-02-01 CA CA002399216A patent/CA2399216A1/en not_active Abandoned
- 2001-02-01 JP JP2001556526A patent/JP2003521351A/ja active Pending
- 2001-02-01 WO PCT/NL2001/000071 patent/WO2001056628A1/en active IP Right Grant
- 2001-02-01 AU AU2001237786A patent/AU2001237786A1/en not_active Abandoned
- 2001-02-01 EP EP01910206A patent/EP1251889B1/de not_active Expired - Lifetime
- 2001-02-01 DE DE60100433T patent/DE60100433T2/de not_active Expired - Lifetime
-
2002
- 2002-08-05 US US10/212,468 patent/US6692790B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2001237786A1 (en) | 2001-08-14 |
CA2399216A1 (en) | 2001-08-09 |
ES2206407T3 (es) | 2004-05-16 |
DE60100433T2 (de) | 2004-04-15 |
WO2001056628A1 (en) | 2001-08-09 |
US20030113438A1 (en) | 2003-06-19 |
EP1251889B1 (de) | 2003-07-02 |
EP1251889A1 (de) | 2002-10-30 |
JP2003521351A (ja) | 2003-07-15 |
ATE244027T1 (de) | 2003-07-15 |
US6692790B2 (en) | 2004-02-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: CHIENNA B.V., BILTHOVEN, NL |
|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: ISOTIS N.V., BILTHOVEN, NL |