BR0108452A - Inibidores da oxidação parcial de ácido graxo no tratamento de insuficiência cardìaca congestiva - Google Patents

Inibidores da oxidação parcial de ácido graxo no tratamento de insuficiência cardìaca congestiva

Info

Publication number
BR0108452A
BR0108452A BR0108452-6A BR0108452A BR0108452A BR 0108452 A BR0108452 A BR 0108452A BR 0108452 A BR0108452 A BR 0108452A BR 0108452 A BR0108452 A BR 0108452A
Authority
BR
Brazil
Prior art keywords
fatty acid
heart failure
congestive heart
treatment
partial oxidation
Prior art date
Application number
BR0108452-6A
Other languages
English (en)
Inventor
Andrew A Wolff
Brent Blackburn
Hani Naief Sabbah
William Clark Stanley
Original Assignee
Cv Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cv Therapeutics Inc filed Critical Cv Therapeutics Inc
Publication of BR0108452A publication Critical patent/BR0108452A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"INIBIDORES DA OXIDAçãO PARCIAL DE áCIDO GRAXO NO TRATAMENTO DE INSUFICIêNCIA CARDìACA CONGESTIVA". São revelados métodos para o tratamento de insuficiência cardíaca congestiva com inibidores parciais da oxidação de ácido graxo. Os compostos aumentam a performance cardíaca sem afetar a freq³ência cardíaca, pressão sang³ínea, ou consumo de oxigênio.
BR0108452-6A 2000-02-18 2001-02-15 Inibidores da oxidação parcial de ácido graxo no tratamento de insuficiência cardìaca congestiva BR0108452A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18356000P 2000-02-18 2000-02-18
US21990800P 2000-07-21 2000-07-21
PCT/US2001/004887 WO2001060348A2 (en) 2000-02-18 2001-02-15 Partial fatty acid oxidation inhibitors in the treatment of congestive heart failure

Publications (1)

Publication Number Publication Date
BR0108452A true BR0108452A (pt) 2003-04-01

Family

ID=26879274

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0108452-6A BR0108452A (pt) 2000-02-18 2001-02-15 Inibidores da oxidação parcial de ácido graxo no tratamento de insuficiência cardìaca congestiva

Country Status (17)

Country Link
US (2) US6528511B2 (pt)
EP (2) EP2033633A3 (pt)
JP (1) JP2004505886A (pt)
KR (1) KR20020075801A (pt)
CN (1) CN1227004C (pt)
AR (1) AR033510A1 (pt)
AU (1) AU778203B2 (pt)
BR (1) BR0108452A (pt)
CA (1) CA2398691A1 (pt)
HK (1) HK1048250A1 (pt)
IL (1) IL151014A0 (pt)
MX (1) MXPA02007639A (pt)
NO (1) NO20023879L (pt)
NZ (1) NZ520780A (pt)
TW (1) TWI235655B (pt)
WO (1) WO2001060348A2 (pt)
ZA (1) ZA200206451B (pt)

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WO2003037323A2 (en) * 2001-10-26 2003-05-08 MEDIGENE AG Gesellschaft für Molekularbiologische Kardiologie und Onkologie Inhibitors of the fatty acid oxidation for prophylaxis and treatment of diseases related to mitochondrial dysfunction
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NZ540548A (en) * 2002-12-05 2008-03-28 Cv Therapeutics Inc Substituted piperazine compounds and their use as fatty acid oxidation inhibitors
EP1723129A1 (en) * 2003-12-18 2006-11-22 Cv Therapeutics, Inc. 1-akan-2-ol substituted piperazine and piperidine compounds
JP2007530543A (ja) † 2004-03-22 2007-11-01 オシリス セラピューティクス，インコーポレイテッド 間葉幹細胞及びその使用法
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US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US8367099B2 (en) 2004-09-28 2013-02-05 Atrium Medical Corporation Perforated fatty acid films
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SG156681A1 (en) * 2004-11-09 2009-11-26 Cv Therapeutics Inc Use of ranolazine in combination with at least one remodeling agent for reversing left ventricular remodeling in the treatment of heart failure
US20060205727A1 (en) * 2005-03-11 2006-09-14 Wayne Kaesemeyer Combination therapy for endothelial dysfunction, angina and diabetes
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US9427423B2 (en) * 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
WO2007047781A2 (en) 2005-10-15 2007-04-26 Atrium Medical Corporation Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings
US7606617B2 (en) * 2006-01-31 2009-10-20 Cardiac Pacemakers, Inc. Urinalysis for the early detection of and recovery from worsening heart failure
EP2051748A2 (en) * 2006-09-08 2009-04-29 Symphony Medical, INC. Intramyocardial patterning for global cardiac resizing and reshaping
US20090012413A1 (en) * 2006-09-08 2009-01-08 Sabbah Hani N Cardiac patterning for improving diastolic function
EP2083875B1 (en) * 2006-11-06 2013-03-27 Atrium Medical Corporation Coated surgical mesh
US9492596B2 (en) * 2006-11-06 2016-11-15 Atrium Medical Corporation Barrier layer with underlying medical device and one or more reinforcing support structures
CA2677931A1 (en) 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of cardiovascular diseases
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CA2678319A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of coronary microvascular diseases
JP2010518171A (ja) * 2007-02-13 2010-05-27 ギリアード・パロ・アルト・インコーポレイテッド 非冠微小血管疾患の処置のためのラノラジンの使用
US20080233191A1 (en) * 2007-03-22 2008-09-25 Brent Blackburn Use of ranolazine for elevated brain-type natriuretic peptide
JP2010523264A (ja) * 2007-04-11 2010-07-15 ヘンリー フォード ヘルス システム 心臓の静脈系を用いた心臓の修復、リサイジング、およびリシェイピング
EA200971073A1 (ru) * 2007-05-31 2010-08-30 Джилид Пало Альто, Инк. Применение ранолазина при повышенном уровне натрийуретического пептида мозгового типа
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AU2009212254A1 (en) * 2008-02-06 2009-08-13 Cv Therapeutics, Inc. Use of Ranolazine for treating pain
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WO2011036677A2 (en) * 2009-09-25 2011-03-31 Lupin Limited Sustained release composition of ranolazine
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Also Published As

Publication number Publication date
US20030119718A1 (en) 2003-06-26
KR20020075801A (ko) 2002-10-05
HK1048250A1 (zh) 2003-03-28
NZ520780A (en) 2006-04-28
US6677342B2 (en) 2004-01-13
CA2398691A1 (en) 2001-08-23
US20010047000A1 (en) 2001-11-29
ZA200206451B (en) 2003-12-31
JP2004505886A (ja) 2004-02-26
IL151014A0 (en) 2003-02-12
MXPA02007639A (es) 2004-08-23
US6528511B2 (en) 2003-03-04
WO2001060348A2 (en) 2001-08-23
AU778203B2 (en) 2004-11-25
AU4150501A (en) 2001-08-27
EP1259230A2 (en) 2002-11-27
CN1227004C (zh) 2005-11-16
EP2033633A2 (en) 2009-03-11
AR033510A1 (es) 2003-12-26
TWI235655B (en) 2005-07-11
NO20023879D0 (no) 2002-08-15
EP2033633A3 (en) 2009-07-08
CN1420766A (zh) 2003-05-28
WO2001060348A3 (en) 2002-01-31
NO20023879L (no) 2002-08-15

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA INT.CL. A61K 31/495, A61K 9/10, A61P 9/04

Ipc: A61K 31/495 (2010.01), A61K 9/10 (2010.01), A61P 9

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11 E 13 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.