DE60020529D1 - Antikörper zur krebsbehandlung und -diagnose - Google Patents

Antikörper zur krebsbehandlung und -diagnose

Info

Publication number
DE60020529D1
DE60020529D1 DE60020529T DE60020529T DE60020529D1 DE 60020529 D1 DE60020529 D1 DE 60020529D1 DE 60020529 T DE60020529 T DE 60020529T DE 60020529 T DE60020529 T DE 60020529T DE 60020529 D1 DE60020529 D1 DE 60020529D1
Authority
DE
Germany
Prior art keywords
antibodies
application
diagnosis
daf
directed against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE60020529T
Other languages
English (en)
Other versions
DE60020529T2 (de
Inventor
J Carter
B Ridgway
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22401661&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60020529(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DE60020529D1 publication Critical patent/DE60020529D1/de
Application granted granted Critical
Publication of DE60020529T2 publication Critical patent/DE60020529T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60020529T 1999-03-01 2000-02-29 Antikörper zur krebsbehandlung und -diagnose Revoked DE60020529T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12226299P 1999-03-01 1999-03-01
US122262P 1999-03-01
PCT/US2000/005352 WO2000052054A2 (en) 1999-03-01 2000-02-29 Antibodies for cancer therapy and diagnosis

Publications (2)

Publication Number Publication Date
DE60020529D1 true DE60020529D1 (de) 2005-07-07
DE60020529T2 DE60020529T2 (de) 2006-04-27

Family

ID=22401661

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60020529T Revoked DE60020529T2 (de) 1999-03-01 2000-02-29 Antikörper zur krebsbehandlung und -diagnose

Country Status (11)

Country Link
US (2) US7288249B2 (de)
EP (1) EP1157041B1 (de)
JP (1) JP2002543044A (de)
AT (1) ATE296839T1 (de)
AU (1) AU770952B2 (de)
CA (1) CA2361877A1 (de)
DE (1) DE60020529T2 (de)
ES (1) ES2243240T3 (de)
IL (2) IL144559A0 (de)
PT (1) PT1157041E (de)
WO (1) WO2000052054A2 (de)

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IL144559A0 (en) 1999-03-01 2002-05-23 Genentech Inc Antibodies for cancer therapy and diagnosis
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US20020115065A1 (en) * 2000-08-28 2002-08-22 Ton Logtenberg Differentially expressed epitopes and uses thereof
US20050053606A1 (en) * 2000-09-11 2005-03-10 KUFE Donald W. MUC1 extracellular domain and cancer treatment compositions and methods derived therefrom
US7611711B2 (en) 2001-01-17 2009-11-03 Vegenics Limited VEGFR-3 inhibitor materials and methods
US20030103971A1 (en) * 2001-11-09 2003-06-05 Kandasamy Hariharan Immunoregulatory antibodies and uses thereof
JP4463475B2 (ja) * 2001-01-31 2010-05-19 バイオジェン アイデック インコーポレイテッド 腫瘍疾患の治療における免疫調節性抗体の使用
US7189800B2 (en) 2001-03-27 2007-03-13 Samuel Bogoch Replikin peptides in rapid replication of glioma cells and in influenza epidemics
US7774144B2 (en) 2001-10-26 2010-08-10 Samuel Bogoch System and method for identifying complex patterns of amino acids
NZ592340A (en) 2001-03-27 2012-12-21 Elenore S Bogoch A method for making a virus vaccine compising Replikin peptides
EP1270732A1 (de) * 2001-06-21 2003-01-02 Schuler, Gerold Transfektion von eukaryotischen Zellen mit linearen Polynukleotiden mittels Elektroporation
CN1578673A (zh) * 2001-09-05 2005-02-09 杰南技术公司 鉴定与涉及异常细胞增殖的疾病相关的多肽抗原的方法和用于治疗此种疾病的组合物
ES2288900T3 (es) * 2001-10-05 2008-02-01 Affimed Therapeutics Ag Anticuerpo de origen humano para inhibir la agregacion de trombocitos.
US8455627B2 (en) * 2001-10-05 2013-06-04 Affimed Therapeutics, Ag Human antibody specific for activated state of platelet integrin receptor GPIIb/IIIa
US8435529B2 (en) 2002-06-14 2013-05-07 Immunomedics, Inc. Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
CN101264325B (zh) 2002-03-01 2017-03-01 免疫医疗公司 Rs7抗体
US9745380B2 (en) * 2002-03-01 2017-08-29 Immunomedics, Inc. RS7 antibodies
US9770517B2 (en) * 2002-03-01 2017-09-26 Immunomedics, Inc. Anti-Trop-2 antibody-drug conjugates and uses thereof
AU2003248982B2 (en) 2002-08-01 2009-12-10 Immunomedics, Inc. Alpha-fetoprotein immu31 antibodies and fusion proteins and methods of use thereof
GB2392723B (en) 2002-09-04 2005-01-12 Bioinvent Int Ab Screening methods
GB0227644D0 (en) * 2002-11-27 2003-01-08 Cancer Rec Tech Ltd Specific binding members and uses thereof
US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
US8494781B2 (en) 2003-06-06 2013-07-23 Samuel Bogoch Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds
WO2005052158A1 (en) * 2003-11-28 2005-06-09 National Research Council Of Canada Anticarcinoma antibidies and uses thereof
JPWO2005094886A1 (ja) * 2004-03-31 2008-02-14 キリンファーマ株式会社 Gpiアンカー蛋白質アゴニストによる調節性t細胞分化誘導・増殖方法およびそのための医薬組成物
US9254315B2 (en) 2004-04-28 2016-02-09 Samuel Bogoch Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds
EP1623996A1 (de) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Verbessertes Verfahren zur Auswahl eines Proteins von einer Bibliothek
WO2006049498A1 (en) * 2004-11-05 2006-05-11 Modiquest B.V. Means and methods for isolating and/or identifying a target molecule
US20050181479A1 (en) * 2005-03-04 2005-08-18 Medimmune, Inc. Periplasmic expression of antibodies using a single signal sequence
US8034902B2 (en) * 2005-05-04 2011-10-11 Quark Pharmaceuticals, Inc. Recombinant antibodies against CD55 and CD59 and uses thereof
US8211648B2 (en) 2005-07-22 2012-07-03 Kalobios Pharmaceuticals, Inc. Secretion of antibodies without signal peptides from bacteria
WO2007033167A2 (en) * 2005-09-12 2007-03-22 The Regents Of The University Of Michigan Compositions and methods for detecting and treating cancer
TW200812615A (en) 2006-03-22 2008-03-16 Hoffmann La Roche Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2
NZ581332A (en) 2007-05-30 2012-06-29 Samuel Bogoch Synthetic replikin peptides against pathogenic infection of invertebrates in aquaculture
AU2013203264B2 (en) * 2007-08-29 2016-07-07 Sanofi Humanized anti-CXCR5 antibodies, derivatives thereof and their uses
EP3354662B1 (de) 2007-08-29 2020-08-19 Sanofi Humanisierte anti-cxcr5-antikörper, derivate davon und deren verwendungen
US8541183B2 (en) 2007-09-11 2013-09-24 Cancer Prevention And Cure, Ltd. Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof
EP2088432A1 (de) * 2008-02-11 2009-08-12 MorphoSys AG Verfahren zur Identifikation eines Antikörpers oder eines Targets
US9233148B2 (en) 2009-01-09 2016-01-12 Samuel Bogoch Replikin-based compounds for prevention and treatment of influenza and methods of differentiating infectivity and lethality in influenza
EP2857522A3 (de) 2009-03-12 2015-10-14 Cancer Prevention And Cure, Ltd. Verfahren zur Identifizierung, Beurteilung, Prävention und Behandlung von Lungenerkrankungen sowie Kits dafür mit geschlechtsspezifischer Krankheitsidentifizierung, Beurteilung, Prävention und Behandlung
WO2010136598A1 (en) 2009-05-29 2010-12-02 Morphosys Ag A collection and methods for its use
US9320784B2 (en) 2009-08-07 2016-04-26 Samuel Bogoch Peptides shared among lethal cancers and therapeutic compositions comprising said peptides
RU2603080C2 (ru) 2010-11-19 2016-11-20 МорфоСис АГ Коллекция и способы ее применения
EP3825693A1 (de) 2011-04-29 2021-05-26 Cancer Prevention And Cure, Ltd. Verfahren zur identifikation und diagnose von lungenkrankheiten mithilfe von klassifizierungssystemen und kits dafür
GB201116364D0 (en) 2011-09-22 2011-11-02 Bioinvent Int Ab Screening methods and uses thereof
US9592289B2 (en) 2012-03-26 2017-03-14 Sanofi Stable IgG4 based binding agent formulations
US9382329B2 (en) 2012-08-14 2016-07-05 Ibc Pharmaceuticals, Inc. Disease therapy by inducing immune response to Trop-2 expressing cells
JP6746845B2 (ja) 2015-04-22 2020-08-26 イミューノメディクス、インコーポレイテッドImmunomedics, Inc. 循環trop−2陽性癌細胞の単離、検出、診断及び/または特徴付け
KR101875912B1 (ko) * 2016-10-13 2018-07-06 한국원자력연구원 암 표적 치료를 위한 방사성 동위원소가 표지된 cd55 표적 항체 및 이의 용도
CN110709936A (zh) 2017-04-04 2020-01-17 肺癌蛋白质组学有限责任公司 用于早期肺癌预后的基于血浆的蛋白质概况分析
WO2020172308A1 (en) * 2019-02-20 2020-08-27 Agonox, Inc. Anti-cd55 antibodies and related compositions and methods
CN116646088B (zh) * 2023-07-27 2023-12-01 广东省人民医院 一种预测方法、装置、设备及介质

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Also Published As

Publication number Publication date
AU770952B2 (en) 2004-03-11
JP2002543044A (ja) 2002-12-17
US7288249B2 (en) 2007-10-30
US20080166698A1 (en) 2008-07-10
ES2243240T3 (es) 2005-12-01
US20030219434A1 (en) 2003-11-27
AU3389800A (en) 2000-09-21
CA2361877A1 (en) 2000-09-08
EP1157041A2 (de) 2001-11-28
WO2000052054A3 (en) 2001-08-23
PT1157041E (pt) 2005-10-31
IL144559A0 (en) 2002-05-23
DE60020529T2 (de) 2006-04-27
WO2000052054A2 (en) 2000-09-08
EP1157041B1 (de) 2005-06-01
IL144559A (en) 2006-12-10
ATE296839T1 (de) 2005-06-15

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Legal Events

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8363 Opposition against the patent
8331 Complete revocation