DE60043235D1 - Lichtemittierende teilchen und deren verwendung bei der diagnostik und therapie - Google Patents
Lichtemittierende teilchen und deren verwendung bei der diagnostik und therapieInfo
- Publication number
- DE60043235D1 DE60043235D1 DE60043235T DE60043235T DE60043235D1 DE 60043235 D1 DE60043235 D1 DE 60043235D1 DE 60043235 T DE60043235 T DE 60043235T DE 60043235 T DE60043235 T DE 60043235T DE 60043235 D1 DE60043235 D1 DE 60043235D1
- Authority
- DE
- Germany
- Prior art keywords
- diagnostics
- therapy
- light
- emitting particles
- emitting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/587—Nanoparticles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Nanotechnology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/465,065 US6703248B1 (en) | 1999-12-15 | 1999-12-15 | Particles for diagnostic and therapeutic use |
PCT/US2000/032361 WO2001044811A2 (en) | 1999-12-15 | 2000-11-27 | Plasminogen activator assay involving an elastase inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60043235D1 true DE60043235D1 (de) | 2009-12-10 |
Family
ID=23846360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60043235T Expired - Lifetime DE60043235D1 (de) | 1999-12-15 | 2000-11-27 | Lichtemittierende teilchen und deren verwendung bei der diagnostik und therapie |
Country Status (6)
Country | Link |
---|---|
US (3) | US6703248B1 (de) |
EP (1) | EP1240522B1 (de) |
JP (1) | JP4773662B2 (de) |
DE (1) | DE60043235D1 (de) |
ES (1) | ES2335473T3 (de) |
WO (1) | WO2001044811A2 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040055965A1 (en) * | 1997-06-13 | 2004-03-25 | Hubig Stephan M. | Recreational water treatment employing singlet oxygen |
US6703248B1 (en) * | 1999-12-15 | 2004-03-09 | Dade Behring Marburg Gmbh | Particles for diagnostic and therapeutic use |
US20040043510A1 (en) * | 2000-07-14 | 2004-03-04 | Nobuyuki Shigetoh | Particle-labeled protein and immuno-chromatograph using the same |
KR20070099519A (ko) * | 2004-09-17 | 2007-10-09 | 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 | 3가 금속 매개 균질 발광 근접 분석 |
WO2007008472A2 (en) * | 2005-07-08 | 2007-01-18 | Colorado Seminary, Which Owns And Operates The University Of Denver | Photoinduced signal amplification through externally sensitized photofragmentation in masked photosensitizers |
WO2007008471A2 (en) * | 2005-07-08 | 2007-01-18 | Colorado Seminary, Which Owns And Operates The University Of Denver | Photolabile system with instantaneous fluorescence reporting function |
JP4902183B2 (ja) * | 2005-12-06 | 2012-03-21 | 日立マクセル株式会社 | 機能性赤外蛍光粒子 |
WO2007070761A2 (en) * | 2005-12-12 | 2007-06-21 | Colorado Seminary, Which Owns And Operates The University Of Denver | Method for encoding and screening combinatorial libraries |
CA2669398C (en) * | 2006-11-13 | 2016-01-05 | Perkinelmer Las, Inc. | Detecting molecular interactions comprising a target-selective binding agent and a target molecule with fluorescence resonance energy transfer (fret) |
US20100105071A1 (en) * | 2007-02-28 | 2010-04-29 | Children's Medical Center Corporation | Methods for predicting the onset of menarche |
CA2684998A1 (en) | 2007-04-30 | 2009-01-29 | Nanogen, Inc. | Multianalyte assay |
US20080305157A1 (en) * | 2007-06-08 | 2008-12-11 | University Of Maryland Office Of Technology Commercialization | Encapsulation and separation of charged organic solutes inside catanionic vesicles |
WO2009026313A1 (en) * | 2007-08-20 | 2009-02-26 | Colorado Seminary, Which Owns And Operates The University Of Denver | Photoinduced signal amplification through externally sensitized photofragmentation in masked photosensitizers and photoamplified fluorescence turn-off system |
US9347947B2 (en) | 2009-03-12 | 2016-05-24 | Siemens Healthcare Diagnostics Inc. | Immunoassays employing non-particulate chemiluminescent reagent |
US20110306148A1 (en) | 2010-06-14 | 2011-12-15 | Siemens Healthcare Diagnostics Inc. | Composition for use as an assay reagent |
US10088490B2 (en) | 2010-08-20 | 2018-10-02 | Siemens Healthcare Diagnostics Inc. | Assay for analytes using multiple receptors |
ES2671238T3 (es) | 2011-08-12 | 2018-06-05 | Siemens Healthcare Diagnostics Inc. | Detección de esteroides sexuales |
ITVR20120049A1 (it) * | 2012-03-19 | 2013-09-20 | Bbs Srl | Soluzione colorata in particolare per uso in metodi chirurgici per il trattamento del corpo umano o animale |
US9244083B2 (en) | 2012-11-30 | 2016-01-26 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for detecting vitamin D |
US20140308751A1 (en) | 2013-04-12 | 2014-10-16 | Siemens Healthcare Diagnostics Inc. | Assays for Analyte Homologs |
WO2015061260A1 (en) * | 2013-10-24 | 2015-04-30 | Siemens Healthcare Diagnostics Inc. | Assays for macromolecular analytes |
WO2015148479A1 (en) * | 2014-03-26 | 2015-10-01 | Siemens Healthcare Diagnostics Inc. | Luminescent oxygen channeling immunoassay utilizing three antibodies and methods of production and use thereof |
US9746484B2 (en) | 2014-06-27 | 2017-08-29 | Siemens Healthcare Diagnostics Inc. | Binding partners specific for vitamin D epimers in vitamin D assays |
US9815907B2 (en) | 2014-06-27 | 2017-11-14 | Siemens Healthcare Diagnostics Inc. | Binding partners specific for vitamin D epimers |
EP4190318A1 (de) | 2016-12-14 | 2023-06-07 | Biora Therapeutics, Inc. | Behandlung einer erkrankung des magen-darm-trakts mit einem jak-hemmer und vorrichtungen |
TW201834710A (zh) | 2016-12-14 | 2018-10-01 | 美商寶珍那提公司 | 以整合素抑制劑治療胃腸道疾病 |
US11523772B2 (en) | 2016-12-14 | 2022-12-13 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immunosuppressant |
EP3554540B1 (de) | 2016-12-14 | 2023-08-02 | Biora Therapeutics, Inc. | Behandlung von erkrankungen des gastrointestinaltraktes mit einem il-12/il-23 inhibitor mit freisetzung anhand einer essbaren vorrichtung |
CA3045310A1 (en) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
EP3554344A1 (de) | 2016-12-14 | 2019-10-23 | Progenity, Inc. | Behandlung der erkrankung des gastrointestinaltraktes mit einem tlr-modulator |
EP3554343A1 (de) | 2016-12-14 | 2019-10-23 | Progenity, Inc. | Behandlung einer erkrankung des gastrointestinaltraktes mit einem il-1-inhibitor |
US11134889B2 (en) | 2016-12-14 | 2021-10-05 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a SMAD7 inhibitor |
WO2018112237A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an il-6r inhibitor |
US20190343425A1 (en) | 2016-12-14 | 2019-11-14 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a tnf inhibitor |
EP3600416B1 (de) | 2017-03-30 | 2023-06-07 | Biora Therapeutics, Inc. | Behandlung einer erkrankung des gastrointestinaltraktes mit einem immunmodulatorischen mittel, das mit einer einnehmbaren vorrichtung freigesetzt wird. |
WO2018183932A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor |
CA3054159A1 (en) | 2017-03-30 | 2018-10-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chst15 inhibitor |
CA3054947A1 (en) | 2017-03-30 | 2018-10-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with live biotherapeutics |
US11596670B2 (en) | 2017-03-30 | 2023-03-07 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with IL-10 or an IL-10 agonist |
US20200306516A1 (en) | 2017-08-14 | 2020-10-01 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with glatiramer or a pharmaceutically acceptable salt thereof |
US20210247398A1 (en) | 2018-07-30 | 2021-08-12 | Siemens Healthcare Diagnostics Inc. | Kits, microfluidics devices, and methods for performing biotin assays |
Family Cites Families (58)
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US4264766A (en) | 1877-09-19 | 1981-04-28 | Hoffmann-La Roche Inc. | Immunological diagnostic reagents |
US3755238A (en) | 1970-12-28 | 1973-08-28 | R Wiita | High gloss and low block coating composition containing plasticized vinyl resin latex and finely divided polyolefin particles |
GB1392670A (en) * | 1973-03-20 | 1975-04-30 | Vnii Fiz Tekhn I Radiotekhnich | Visual colour indicators of ionizing radiation doses |
US3996056A (en) | 1973-04-10 | 1976-12-07 | Andrews Paper & Chemical Co. | Diazotype reproduction layer formed from matrix of spheric particle polystyrene pigment and diazotype components |
CA1101330A (en) | 1977-09-19 | 1981-05-19 | Ernst A. Fischer | Immunological material bonded to carboxylated latex polymer and process for making it |
US4388296A (en) | 1978-03-27 | 1983-06-14 | Hiram Hart | Energy-emitting latex-particulates |
US4318707A (en) | 1978-11-24 | 1982-03-09 | Syva Company | Macromolecular fluorescent quencher particle in specific receptor assays |
US4481136A (en) * | 1979-09-07 | 1984-11-06 | Syva Company | Alkyl substituted fluorescent compounds and conjugates |
US4265766A (en) * | 1979-11-15 | 1981-05-05 | Crossley Leonard S | Chicken marinade draining system |
EP0054685B1 (de) | 1980-12-23 | 1986-07-09 | Roche Diagnostics GmbH | Hydrophile Latexpartikel, Verfahren zu deren Herstellung und deren Verwendung |
US4650770A (en) | 1981-04-27 | 1987-03-17 | Syntex (U.S.A.) Inc. | Energy absorbing particle quenching in light emitting competitive protein binding assays |
US4419453A (en) | 1981-09-28 | 1983-12-06 | The Dow Chemical Company | Immunological agglutination assays with dyed or colored latex and kits |
US4483929A (en) | 1982-05-03 | 1984-11-20 | Liposome Technology Incorporated | Liposomes with glycolipid-linked antibodies |
US4487855A (en) | 1983-02-15 | 1984-12-11 | Shih Yen Jer | Colored latexes; methods for making same and colored finely divided products |
US4652533A (en) * | 1983-04-28 | 1987-03-24 | Pandex Laboratories, Inc. | Method of solid phase immunoassay incorporating a luminescent label |
US4699826A (en) | 1984-04-27 | 1987-10-13 | Becton, Dickinson And Company | Fluorescently labeled microbeads |
US5145774A (en) * | 1984-08-28 | 1992-09-08 | Syntex (U.S.A.) Inc. | Fluorescent dyes |
US4745075A (en) | 1984-09-06 | 1988-05-17 | Burroughs Wellcome Co. | Diagnostic test methods |
US4719182A (en) | 1985-03-18 | 1988-01-12 | Eastman Kodak Company | Fluorescent labels and labeled species and their use in analytical elements and determinations |
US4735907A (en) | 1985-03-18 | 1988-04-05 | Eastman Kodak Company | Stabilized fluorescent rare earth labels and labeled physiologically reactive species |
US4806488A (en) * | 1985-09-06 | 1989-02-21 | Syntex (U.S.A.) Inc. | Ligand-receptor assays employing squarate dye compositions |
CA1291031C (en) | 1985-12-23 | 1991-10-22 | Nikolaas C.J. De Jaeger | Method for the detection of specific binding agents and their correspondingbindable substances |
US4891324A (en) | 1987-01-07 | 1990-01-02 | Syntex (U.S.A.) Inc. | Particle with luminescer for assays |
US5194300A (en) | 1987-07-15 | 1993-03-16 | Cheung Sau W | Methods of making fluorescent microspheres |
US5132242A (en) | 1987-07-15 | 1992-07-21 | Cheung Sau W | Fluorescent microspheres and methods of using them |
US4978625A (en) * | 1987-10-19 | 1990-12-18 | Becton, Dickinson And Company | Fluorescence immunoassay using water insoluble dyes |
US5053443A (en) | 1987-12-18 | 1991-10-01 | Eastman Kodak Company | Methods of preparing a polymeric latex composition and water-insoluble biological reagent |
US5234841A (en) | 1987-12-18 | 1993-08-10 | Eastman Kodak Company | Methods of preparing a polymeric latex composition and water-insoluble biological reagent |
US5284752A (en) | 1987-12-18 | 1994-02-08 | Eastman Kodak Company | Methods of preparing a polymeric latex composition and water-insoluble biological reagent |
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WO1989012232A1 (en) | 1988-06-08 | 1989-12-14 | London Diagnostics, Inc. | Assays utilizing sensitizer-induced production of detectable signals |
JPH02114180A (ja) | 1988-09-06 | 1990-04-26 | Eastman Kodak Co | 分析試薬、要素及び方法用のラテックス粒子 |
IE71197B1 (en) | 1988-11-14 | 1997-02-12 | Akzo Nv | Aqueous suspension for diagnostic tests |
US5326692B1 (en) | 1992-05-13 | 1996-04-30 | Molecular Probes Inc | Fluorescent microparticles with controllable enhanced stokes shift |
US5157084A (en) | 1990-10-12 | 1992-10-20 | The Dow Chemical Company | Process of making hollow polymer latex particles |
US5340716A (en) | 1991-06-20 | 1994-08-23 | Snytex (U.S.A.) Inc. | Assay method utilizing photoactivated chemiluminescent label |
ATE246360T1 (de) * | 1991-05-22 | 2003-08-15 | Dade Behring Marburg Gmbh | Partikel, die eine zusammensetzung beinhalten, die eine chemilumineszierende verbindung umfassen |
US5578498A (en) * | 1991-05-22 | 1996-11-26 | Behringwerke Ag | Metal chelate containing compositions for use in chemiluminescent assays |
US5154887A (en) * | 1991-05-28 | 1992-10-13 | Eastman Kodak Company | Phenalenimine fluorescent dyes and their use in analytical compositions, elements and methods |
DE69229960T2 (de) | 1991-12-13 | 2000-01-05 | Bion Diagnostic Sciences, Inc. | Agglutierungsassays und kolloide farbstoffe verwendende testsätze |
JPH07509245A (ja) * | 1992-07-20 | 1995-10-12 | デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 新規化学発光化合物およびその使用方法 |
EP0653066B1 (de) | 1992-07-31 | 1998-01-28 | BEHRINGWERKE Aktiengesellschaft | Photoaktivierbare chemiluminizierende matrices |
US5518808A (en) * | 1992-12-18 | 1996-05-21 | E. I. Du Pont De Nemours And Company | Luminescent materials prepared by coating luminescent compositions onto substrate particles |
EP0613166B1 (de) * | 1993-02-26 | 2000-04-19 | E.I. Du Pont De Nemours And Company | Verfahren zur Herstellung eines Plasma-Anzeigegeräts |
FR2707658B1 (fr) * | 1993-07-12 | 1995-11-24 | Prolabo Sa | Latex fluorescent comportant au moins deux fluorochromes, procédé d'obtention et application dudit latex comme marqueur, notamment en biologie. |
ATE177842T1 (de) * | 1993-09-03 | 1999-04-15 | Behringwerke Ag | Fluoreszenz-sauerstoffkanalisation-immunteste |
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US6197482B1 (en) * | 1999-05-14 | 2001-03-06 | Eastman Kodak Company | Polymer overcoat for imaging elements |
US6703248B1 (en) * | 1999-12-15 | 2004-03-09 | Dade Behring Marburg Gmbh | Particles for diagnostic and therapeutic use |
-
1999
- 1999-12-15 US US09/465,065 patent/US6703248B1/en not_active Expired - Lifetime
-
2000
- 2000-11-27 EP EP00980822A patent/EP1240522B1/de not_active Expired - Lifetime
- 2000-11-27 DE DE60043235T patent/DE60043235D1/de not_active Expired - Lifetime
- 2000-11-27 WO PCT/US2000/032361 patent/WO2001044811A2/en active Application Filing
- 2000-11-27 ES ES00980822T patent/ES2335473T3/es not_active Expired - Lifetime
- 2000-11-27 JP JP2001545848A patent/JP4773662B2/ja not_active Expired - Lifetime
-
2003
- 2003-12-24 US US10/745,972 patent/US7022529B2/en not_active Expired - Lifetime
-
2005
- 2005-11-14 US US11/273,275 patent/US7709273B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1240522B1 (de) | 2009-10-28 |
EP1240522A2 (de) | 2002-09-18 |
ES2335473T3 (es) | 2010-03-29 |
US20040241711A1 (en) | 2004-12-02 |
WO2001044811A2 (en) | 2001-06-21 |
JP2003517608A (ja) | 2003-05-27 |
US7709273B2 (en) | 2010-05-04 |
US6703248B1 (en) | 2004-03-09 |
JP4773662B2 (ja) | 2011-09-14 |
WO2001044811A3 (en) | 2002-01-31 |
US7022529B2 (en) | 2006-04-04 |
US20060121506A1 (en) | 2006-06-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |