DE60040543D1 - Verfahren zum mengen von magnetteilchen mit einer flüssigkeit - Google Patents

Verfahren zum mengen von magnetteilchen mit einer flüssigkeit

Info

Publication number
DE60040543D1
DE60040543D1 DE60040543T DE60040543T DE60040543D1 DE 60040543 D1 DE60040543 D1 DE 60040543D1 DE 60040543 T DE60040543 T DE 60040543T DE 60040543 T DE60040543 T DE 60040543T DE 60040543 D1 DE60040543 D1 DE 60040543D1
Authority
DE
Germany
Prior art keywords
magnets
magnetic
particles
fluid
line
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60040543T
Other languages
English (en)
Inventor
Hermanus Johannes Kreuwel
Emiel Gerebern Verwimp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux BV
Original Assignee
Biomerieux BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux BV filed Critical Biomerieux BV
Application granted granted Critical
Publication of DE60040543D1 publication Critical patent/DE60040543D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/28Magnetic plugs and dipsticks
    • B03C1/288Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/451Magnetic mixers; Mixers with magnetically driven stirrers wherein the mixture is directly exposed to an electromagnetic field without use of a stirrer, e.g. for material comprising ferromagnetic particles or for molten metal
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/025High gradient magnetic separators
    • B03C1/031Component parts; Auxiliary operations
    • B03C1/033Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0332Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/18Magnetic separation whereby the particles are suspended in a liquid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical or biological applications
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Accessories For Mixers (AREA)
  • Soft Magnetic Materials (AREA)
DE60040543T 1999-07-19 2000-07-14 Verfahren zum mengen von magnetteilchen mit einer flüssigkeit Expired - Lifetime DE60040543D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99202354 1999-07-19
PCT/EP2000/006789 WO2001005510A1 (en) 1999-07-19 2000-07-14 Device and method for mixing magnetic particles with a fluid

Publications (1)

Publication Number Publication Date
DE60040543D1 true DE60040543D1 (de) 2008-11-27

Family

ID=8240468

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60040543T Expired - Lifetime DE60040543D1 (de) 1999-07-19 2000-07-14 Verfahren zum mengen von magnetteilchen mit einer flüssigkeit

Country Status (9)

Country Link
US (1) US6764859B1 (de)
EP (1) EP1202808B1 (de)
JP (1) JP4856831B2 (de)
AT (1) ATE411110T1 (de)
AU (1) AU777180B2 (de)
CA (1) CA2379773C (de)
DE (1) DE60040543D1 (de)
ES (1) ES2315238T3 (de)
WO (1) WO2001005510A1 (de)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884357B2 (en) * 1995-02-21 2005-04-26 Iqbal Waheed Siddiqi Apparatus and method for processing magnetic particles
DE19823719B4 (de) * 1998-05-27 2011-12-15 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zum Aufkonzentrieren von Substanzen
JP2001091521A (ja) * 1999-09-21 2001-04-06 Olympus Optical Co Ltd 自動分析装置
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
FR2826882B1 (fr) * 2001-07-09 2003-09-12 Bio Merieux Procede de traitement de particules magnetiques et configurations d'aimants permettant la mise en oeuvre de ce procede
JP2005523692A (ja) * 2002-04-26 2005-08-11 アボット・ラボラトリーズ 生物学的検定において磁性粒子を処理するための構造体および方法
JP2005532072A (ja) * 2002-07-10 2005-10-27 マサチューセッツ・インスティテュート・オブ・テクノロジー サンプルから核酸を単離するための装置および方法
AU2003263986A1 (en) * 2002-08-01 2004-02-23 Arizona Board Of Regents Dynamically formed rotors for lock-in amplifier detection
FR2845298B1 (fr) * 2002-10-08 2004-11-12 Commissariat Energie Atomique Dispositif pour le melange de fluides
DE10251570A1 (de) * 2002-11-06 2004-05-19 Dürr Ecoclean GmbH Feststoffseparator
US20060248945A1 (en) * 2003-04-15 2006-11-09 Koninklijke Philips Electronics N.V. Method and apparatus for improved determination of spatial non-agglomerated magnetic particle distribution in an area of examination
WO2005011867A2 (en) 2003-07-31 2005-02-10 Handylab, Inc. Processing particle-containing samples
FI20040159A0 (fi) 2003-10-20 2004-02-02 Bio Mobile Oy Magneettinen siirtomenetelmä, mikropartikkelien siirtolaite, ja reaktioyksikkö
WO2005068059A1 (en) * 2004-01-07 2005-07-28 Levtech, Inc. Mixing bag with integral sparger and sensor receiver
WO2005072855A1 (en) 2004-01-28 2005-08-11 Drexel University Magnetic fluid manipulators and methods for their use
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
MXPA06014099A (es) * 2004-06-04 2007-05-09 Xcellerex Inc Sistemas biorreactores desechables y metodos.
US8211386B2 (en) 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
AU2011202810B2 (en) * 2004-07-26 2013-06-27 Biomerieux B.V. Device and method for separating, mixing and concentrating magnetic particles with a fluid and use thereof in purification methods
EP1621890A1 (de) * 2004-07-26 2006-02-01 bioMerieux B.V. Gerät und Methode zur Separation, Mischung und Konzentrierung magnetischer Partikel mit Flüssigkeiten und deren Verwendungen in Reinigungsmethoden
WO2006068935A1 (en) * 2004-12-21 2006-06-29 Instrumentation Laboratory Company Resuspension of magnetizable particles
WO2006104962A1 (en) * 2005-03-28 2006-10-05 Becton, Dickinson And Company An improved system and method for stirring suspended solids in liquid media
CN101203757A (zh) * 2005-06-23 2008-06-18 皇家飞利浦电子股份有限公司 用于移动磁性粒子的设备
JP4692200B2 (ja) * 2005-10-06 2011-06-01 横河電機株式会社 化学処理用カートリッジおよびその使用方法
US7754148B2 (en) 2006-12-27 2010-07-13 Progentech Limited Instrument for cassette for sample preparation
US7727473B2 (en) 2005-10-19 2010-06-01 Progentech Limited Cassette for sample preparation
US20070207272A1 (en) * 2006-03-03 2007-09-06 Puri Ishwar K Method and apparatus for magnetic mixing in micron size droplets
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
EP2001990B1 (de) 2006-03-24 2016-06-29 Handylab, Inc. Integriertes system zur verarbeitung von mikrofluidischen proben und verwendungsverfahren
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8183053B1 (en) * 2006-05-09 2012-05-22 Flir Systems, Inc. Preconcentrator media and methods for preconcentration of an analyte
US8999732B2 (en) * 2006-06-21 2015-04-07 Spinomix, S.A. Method for manipulating magnetic particles in a liquid medium
US8585279B2 (en) * 2006-06-21 2013-11-19 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
EP3089173A1 (de) 2006-06-21 2016-11-02 Spinomix S.A. Verfahren zur handhabung magnetischer partikel in einem flüssigen medium
US8870446B2 (en) 2006-06-21 2014-10-28 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
US20140216917A1 (en) * 2006-10-30 2014-08-07 Stc.Unm Magnetically Susceptible Particles and Apparatuses for Mixing the Same
US8283185B2 (en) * 2006-10-30 2012-10-09 Stc.Unm Magnetically susceptible particles and apparatuses for mixing the same
WO2008060604A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
EP2091647A2 (de) 2006-11-14 2009-08-26 Handylab, Inc. Mikrofluidisches system für parallele amplifikation und erkennung von polynukleotiden
US7883265B2 (en) * 2007-06-01 2011-02-08 Applied Biosystems, Llc Devices, systems, and methods for preparing emulsions
IL184183A0 (en) 2007-06-25 2007-10-31 Benjamin Alspector Bi directional transfer of an aliquot of fluid between compartments
US8324372B2 (en) 2007-07-13 2012-12-04 Handylab, Inc. Polynucleotide capture materials, and methods of using same
AU2015249160B2 (en) * 2007-07-13 2017-10-12 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US20090027998A1 (en) * 2007-07-25 2009-01-29 Abbott Laboratories Magnetic mixer
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
WO2010013312A1 (ja) * 2008-07-29 2010-02-04 株式会社フォスメガ 送液装置及び方法、攪拌装置及び方法、マイクロリアクター
US8623663B2 (en) 2008-07-31 2014-01-07 Empire Technology Development Llc Reaction apparatus and process
US20110263044A1 (en) * 2008-07-31 2011-10-27 Eads Deutschland Gmbh Device and method for the automatic detection of biological particles
WO2010013335A1 (ja) * 2008-07-31 2010-02-04 株式会社フォスメガ 反応装置及び方法
US8377708B2 (en) 2008-07-31 2013-02-19 Empire Technology Development Llc Reaction apparatus and process
EP2191900B1 (de) * 2008-11-28 2016-03-30 F. Hoffmann-La Roche AG System und Verfahren zur Behandlung von Nukleinsäuren enthaltenden Fluiden
EP2208531A1 (de) * 2008-12-30 2010-07-21 Atonomics A/S Verteilung von Partikeln in einem Kapillarkanal durch Anwendung eines Magnetfelds
JP5292267B2 (ja) 2009-12-16 2013-09-18 株式会社日立ハイテクノロジーズ 試料処理装置、試料処理方法及びこれらに使用する反応容器
KR20160088958A (ko) 2010-02-23 2016-07-26 루미넥스 코포레이션 일체화된 샘플 제조, 반응 및 검출을 위한 장치 및 방법
US9725754B2 (en) 2010-07-29 2017-08-08 Sean F. Boyle Generic sample preparation
DE112011102524T5 (de) 2010-07-29 2013-07-11 Roche Diagnostics Gmbh Präparation generischer Proben
WO2012019107A1 (en) 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Magnetic immunosensor and method of use
EP2600973B1 (de) 2010-08-05 2016-05-25 Abbott Point Of Care, Inc. Immuntestverfahren und gerät mittels magnetisches bead-basierter affinitätssäule
US11402375B2 (en) 2010-08-05 2022-08-02 Abbott Point Of Care Inc. Magnetic immunosensor with trench configuration and method of use
US9329175B2 (en) 2010-08-05 2016-05-03 Abbott Point Of Care Inc. Oscillating immunoassay method and device
ES2617599T3 (es) 2011-04-15 2017-06-19 Becton, Dickinson And Company Termociclador microfluídico de exploración en tiempo real y métodos para termociclado sincronizado y detección óptica de exploración
EP2705130B1 (de) 2011-05-04 2016-07-06 Luminex Corporation Vorrichtung und verfahren für integrierte probenzubereitung, -reaktion und -erkennung
JP5650056B2 (ja) * 2011-05-30 2015-01-07 株式会社日立ハイテクノロジーズ 試料処理装置、および試料処理方法
DE102011109332A1 (de) 2011-08-03 2013-02-07 Eppendorf Ag Laborvorrichtung und Verfahren zur Behandlung von Laborproben
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
RU2622432C2 (ru) 2011-09-30 2017-06-15 Бектон, Дикинсон Энд Компани Унифицированная полоска для реактивов
EP2773892B1 (de) 2011-11-04 2020-10-07 Handylab, Inc. Vorrichtung zur vorbereitung von polynukleotidproben
EP2618157A1 (de) * 2012-01-17 2013-07-24 Eppendorf Ag Laborvorrichtung zur Behandlung eines Probenaufnahmeabschnitts mit einer magnetischen Werkzeugvorrichtung, magnetische Werkzeugvorrichtung, Probenaufnahmevorrichtung zur Verwendung mit der magnetischen Werkzeugvorrichtung und Verfahren zur Durchführung eines Arbeitsschrittes mit mindestens einer Flüssigkeitsprobe unter Verwendung eines magnetischen Feldes
WO2013116769A1 (en) 2012-02-03 2013-08-08 Becton, Dickson And Company External files for distribution of molecular diagnostic tests and determination of compatibility between tests
JP2012152213A (ja) * 2012-02-14 2012-08-16 Tamagawa Seiki Co Ltd 液体中の磁性粒子の集合/分散装置
JP5347121B2 (ja) * 2012-02-14 2013-11-20 多摩川精機株式会社 液体中の磁性粒子の集合/分散装置
JP2012152734A (ja) * 2012-02-14 2012-08-16 Tamagawa Seiki Co Ltd 液体中の磁性粒子の集合/分散装置
US9339026B2 (en) 2012-06-14 2016-05-17 Therapeutic Proteins International, LLC Pneumatically agitated and aerated single-use bioreactor
US9446406B2 (en) 2012-06-29 2016-09-20 Biocontrol Systems, Inc. Sample collection and bioluminescent analysis system
CN104471369B (zh) 2012-07-06 2016-09-21 株式会社日立高新技术 核酸提取用成套工具及核酸提取装置
JP2014093988A (ja) * 2012-11-12 2014-05-22 Seiko Epson Corp 固相担体の操作方法及び固相担体の操作装置
CN105008513A (zh) * 2012-12-19 2015-10-28 戴克斯纳有限责任公司 混合设备和方法
US9234090B2 (en) 2013-04-10 2016-01-12 Xerox Corporation Method and system for magnetic actuated milling for pigment dispersions
US8871420B1 (en) 2013-04-10 2014-10-28 Xerox Corporation Method and system for magnetic actuated mixing to prepare latex emulsion
US9358513B2 (en) 2013-04-10 2016-06-07 Xerox Corporation Method and system for magnetic actuated mixing
US9512328B2 (en) * 2013-08-22 2016-12-06 Xerox Corporation Method and system for magnetic particle assisted add-on module on inkjet printer to prevent ink from settling
US20150290651A1 (en) * 2014-04-09 2015-10-15 Xerox Corporation Magnetic milling systems and methods
WO2015177934A1 (ja) * 2014-05-23 2015-11-26 株式会社島津製作所 磁性体粒子の操作方法および磁性体粒子操作用デバイス
CN106457196B (zh) * 2014-05-23 2019-04-26 株式会社岛津制作所 磁性物质颗粒的操作方法和磁性物质颗粒操作用装置
DE202014102945U1 (de) * 2014-06-27 2014-07-14 Analytik Jena Ag Heiz- und Magnetmodul für eine Vorrichtung zur Aufreinigung von Nukleinsäuren
US20160008820A1 (en) 2014-07-10 2016-01-14 Xerox Corporation Magnetic actuated-milled pigment dispersions and process for making thereof
JP6610550B2 (ja) * 2014-09-19 2019-11-27 日立化成ダイアグノスティックス・システムズ株式会社 磁性担体粒子の洗浄方法、磁性担体粒子の洗浄装置、及び磁性担体粒子を用いる免疫学的測定方法
US9663780B2 (en) 2014-10-15 2017-05-30 Alpaqua Engineering, LLC Solid-core ring-magnet
ES2717535T3 (es) 2014-12-08 2019-06-21 Hoffmann La Roche Procedimiento para la medición de vitamina D
DE102015211394B4 (de) * 2015-06-19 2022-07-28 Ist Innuscreen Gmbh Vorrichtung und Verfahren zur Extraktion von Nukleinsäuren
US10851368B2 (en) 2015-04-23 2020-12-01 Aj Innuscreen Gmbh Device and process for automated extraction of nucleic acids
WO2016183032A1 (en) 2015-05-08 2016-11-17 Biomagnetic Solutions Llc Apparatus and method for immunomagnetic cell separation
JP6947728B2 (ja) 2015-09-14 2021-10-13 メディシーブ リミテッド 磁気濾過装置および方法
GB2550390A (en) * 2016-05-18 2017-11-22 Anton Michel Continuous moving bed chromatography
AU2017304767A1 (en) 2016-07-28 2019-01-17 Medisieve Ltd. Magnetic mixer and method
GB201617388D0 (en) * 2016-10-13 2016-11-30 Randox Laboratories Limited Method of extracting material from a fluid and extractor
EP3532847B1 (de) * 2016-10-31 2022-12-14 Amgen Inc. Reinigungssysteme und -verfahren
EP3594692B1 (de) * 2017-03-08 2021-10-13 Hitachi High-Tech Corporation Vorrichtung zur automatischen analyse und verfahren zur automatischen analyse
DE102017204267B4 (de) 2017-03-14 2021-05-27 Aj Innuscreen Gmbh Verfahren zur anreicherung von zellen aus einer probe und der nachfolgenden nukleinsäureisolierung aus diesen zellen
CN107144690B (zh) * 2017-06-28 2019-04-23 苏州长光华医生物医学工程有限公司 一种磁铁单侧排布的分析仪磁清洗分离装置
CN107144689B (zh) * 2017-06-28 2019-04-12 苏州长光华医生物医学工程有限公司 一种磁铁单侧排布的分析仪磁清洗分离机构
US20190022665A1 (en) * 2017-07-24 2019-01-24 Dexter Magnetic Technologies, Inc. Device for Magnetic Bead Resuspension
US10399048B2 (en) * 2017-08-03 2019-09-03 Agilent Technologies, Inc. Sample processing apparatus with integrated heater, shaker and magnet
KR20200091898A (ko) * 2017-12-01 2020-07-31 글로벌 라이프 사이언시즈 솔루션즈 유에스에이 엘엘씨 세포 농축 및 격리 방법
CN110082291B (zh) * 2018-01-25 2022-08-05 深圳市新产业生物医学工程股份有限公司 吸附机构、清洗装置、化学发光检测仪及清洗方法
GB201801325D0 (en) * 2018-01-26 2018-03-14 Francis Crick Institute Ltd Test receptacle rack
US12077743B2 (en) 2018-02-09 2024-09-03 Global Life Sciences Solutions Usa Llc Apparatus for fluid line management in a bioprocessing system
US11932842B2 (en) 2018-02-09 2024-03-19 Global Life Sciences Solutions Usa Llc Bioprocessing apparatus
US11920119B2 (en) 2018-02-09 2024-03-05 Global Life Sciences Solutions Usa Llc Systems and methods for bioprocessing
JP2018161649A (ja) * 2018-04-10 2018-10-18 株式会社島津製作所 磁性体粒子の操作方法および磁性体粒子操作用デバイス
WO2019216887A1 (en) 2018-05-08 2019-11-14 Biomagnetic Solutions Llc A rigid chamber for cell separation from a flexible disposable bag
US10903184B2 (en) * 2018-08-22 2021-01-26 International Business Machines Corporation Filler particle position and density manipulation with applications in thermal interface materials
US11242519B2 (en) 2018-08-23 2022-02-08 Alpaqua Engineering, LLC Discontinuous wall hollow core magnet
US11154828B2 (en) * 2018-09-14 2021-10-26 Uchicago Argonne, Llc Turbulent mixing by microscopic self-assembled spinners
CN113088430B (zh) * 2021-04-09 2024-07-19 广州新成生物科技有限公司 一种旋转式吸磁装置
GB2622826A (en) * 2022-09-29 2024-04-03 Kromek Ltd Apparatus and method for the extraction of material

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985649A (en) * 1974-11-25 1976-10-12 Eddelman Roy T Ferromagnetic separation process and material
JPS5845754A (ja) * 1981-09-14 1983-03-17 株式会社富士電機総合研究所 移動磁界式粉砕装置
JPH0227896Y2 (de) * 1985-03-06 1990-07-26
JPH0628594B2 (ja) * 1985-08-07 1994-04-20 東ソー株式会社 生化学反応用撹拌装置
JPS6239845A (ja) * 1985-08-14 1987-02-20 Mitsubishi Paper Mills Ltd 感光熱転写型記録シ−ト
FR2679660B1 (fr) 1991-07-22 1993-11-12 Pasteur Diagnostics Procede et dispositif magnetique d'analyse immunologique sur phase solide.
US5897783A (en) * 1992-09-24 1999-04-27 Amersham International Plc Magnetic separation method
DE69434867T2 (de) * 1993-02-01 2007-05-16 Thermo Electron Oy Gerät zur Bestimmung eines Analyten in einer Probe
DE4423878A1 (de) 1994-07-07 1996-01-11 Boehringer Mannheim Gmbh Vorrichtung und Verfahren zum Abscheiden von magnetischen Mikropartikeln
JP3607320B2 (ja) * 1994-09-02 2005-01-05 株式会社日立製作所 微粒子を用いた分析における固相の回収方法及び装置
DE69600924T2 (de) * 1995-02-21 1999-06-10 Iqbal W. Dr. Brea Calif. Siddiqi Apparat und verfahren zum mischen und trennen durch verwendung von magnetischen teilchen
JPH08233826A (ja) * 1995-02-28 1996-09-13 Suzuki Motor Corp 免疫反応測定装置用恒温槽
JP2965131B2 (ja) * 1995-07-07 1999-10-18 東洋紡績株式会社 核酸結合用磁性担体およびそれを用いる核酸単離方法
JP3551293B2 (ja) * 1998-02-02 2004-08-04 東洋紡績株式会社 核酸抽出装置
ATE426456T1 (de) * 1998-05-01 2009-04-15 Gen Probe Inc Automatische diagnostische analysevorrichtung
JP3725339B2 (ja) * 1998-06-30 2005-12-07 株式会社東芝 反応装置および反応方法および火力発電システム
JP2000254472A (ja) * 1999-03-15 2000-09-19 Toshiba Corp 攪拌装置と攪拌方法

Also Published As

Publication number Publication date
EP1202808A1 (de) 2002-05-08
US6764859B1 (en) 2004-07-20
ATE411110T1 (de) 2008-10-15
AU6564200A (en) 2001-02-05
CA2379773A1 (en) 2001-01-25
AU777180B2 (en) 2004-10-07
EP1202808B1 (de) 2008-10-15
CA2379773C (en) 2009-01-20
JP2003504195A (ja) 2003-02-04
ES2315238T3 (es) 2009-04-01
JP4856831B2 (ja) 2012-01-18
WO2001005510A1 (en) 2001-01-25

Similar Documents

Publication Publication Date Title
DE60040543D1 (de) Verfahren zum mengen von magnetteilchen mit einer flüssigkeit
US5976369A (en) Magnetic separation apparatus
ATE342512T1 (de) Vorrichtung und verfahren zum behandeln von magnetpartikeln
Gao et al. Label-free manipulation via the magneto-Archimedes effect: fundamentals, methodology and applications
US3676337A (en) Process for magnetic separation
US5458785A (en) Magnetic separation method
Lim et al. Nano/micro-scale magnetophoretic devices for biomedical applications
DE69701418D1 (de) Verfahren und Vorrichtung zum Waschen, zur Resuspension, zum Wiedersammeln und zur Lokalisierung von magnetisierbaren Teilchen in der magnetischen Trennungstechnik von Proben
DE69600924D1 (de) Apparat und verfahren zum mischen und trennen durch verwendung von magnetischen teilchen
ATE279987T1 (de) Verfahren zur trennung von plastikgemischen basierend auf der magnetoarchimedischen-schwebung
DE60029528D1 (de) Trennungsverfahren von Substanzen durch Dielektrophoresis
WO2002066165A3 (en) Method and apparatus for magnetic separation of particles
AU5880199A (en) Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology
Mills The lodestone: History, physics, and formation
EP0589636B1 (de) Verfahren und Vorrichtung zur magnetischen Abscheidung
ATE310585T1 (de) Behandlungsverfahren für magnetische teilchen und bioanalyse-apparat mit magnetverwendung
BRPI0815155B1 (pt) Método para colocar ou recolocar em susensão partículas magneticamente atrativas
DE60023185D1 (de) Apparat und verfahren zum mischen und trennen unter benützung magnetischer teilchen
Zborowski et al. Magnetic cell manipulation and sorting
DE69019408D1 (de) Verfahren und Apparat zur Verminderung von Basisfeldveränderungen in einem magnetischen Resonanzgerät, verursacht durch gepulste magnetische Feldgradienten.
MXPA06000233A (es) Dispositivo para el transporte de particulas magneticas y la herramienta que incluye el mismo.
Rivas et al. Rock magnetism and pedogenetic processes in Luvisol profiles: Examples from Central Russia and Central Mexico
RU2012144814A (ru) Устройство и способ для магнитного разделения текучей среды
DE59107967D1 (de) Verfahren und Vorrichtung zum Kompensieren von Feldstörungen in Magnetfeldern
US20200030816A1 (en) Device for magnetic bead separation and resuspension

Legal Events

Date Code Title Description
8364 No opposition during term of opposition