DE60037514T2 - Wässrige immunologische adjuvantzusammensetzungen aus monophosphoryllipid a - Google Patents
Wässrige immunologische adjuvantzusammensetzungen aus monophosphoryllipid a Download PDFInfo
- Publication number
- DE60037514T2 DE60037514T2 DE60037514T DE60037514T DE60037514T2 DE 60037514 T2 DE60037514 T2 DE 60037514T2 DE 60037514 T DE60037514 T DE 60037514T DE 60037514 T DE60037514 T DE 60037514T DE 60037514 T2 DE60037514 T2 DE 60037514T2
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- lipid
- surfactant
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Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
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- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US338182 | 1999-06-22 | ||
| US09/338,182 US6491919B2 (en) | 1997-04-01 | 1999-06-22 | Aqueous immunologic adjuvant compostions of monophosphoryl lipid A |
| PCT/US2000/016384 WO2000078353A2 (en) | 1999-06-22 | 2000-06-14 | Aqueous immunologic adjuvant compositions of monophosphoryl lipid a |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60037514D1 DE60037514D1 (de) | 2008-01-31 |
| DE60037514T2 true DE60037514T2 (de) | 2008-12-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60037514T Expired - Fee Related DE60037514T2 (de) | 1999-06-22 | 2000-06-14 | Wässrige immunologische adjuvantzusammensetzungen aus monophosphoryllipid a |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6491919B2 (enExample) |
| EP (1) | EP1194166B1 (enExample) |
| JP (1) | JP2003502388A (enExample) |
| AT (1) | ATE381344T1 (enExample) |
| AU (1) | AU775942B2 (enExample) |
| CA (1) | CA2376829A1 (enExample) |
| DE (1) | DE60037514T2 (enExample) |
| ES (1) | ES2296629T3 (enExample) |
| WO (1) | WO2000078353A2 (enExample) |
Families Citing this family (38)
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| GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| GB9820525D0 (en) | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| GB0000891D0 (en) * | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
| BR0110975A (pt) * | 2000-05-19 | 2004-03-23 | Corixa Corp | Tratamento profilático e terapêutico de doenças infecciosas ou outras doenças com compostos à base de mono- e disacarìdeos |
| US20030139356A1 (en) * | 2001-05-18 | 2003-07-24 | Persing David H. | Prophylactic and therapeutic treatment of infectious and other diseases with mono- and disaccharide-based compounds |
| US20030031684A1 (en) * | 2001-03-30 | 2003-02-13 | Corixa Corporation | Methods for the production of 3-O-deactivated-4'-monophosphoryl lipid a (3D-MLA) |
| JP2009509970A (ja) * | 2005-09-22 | 2009-03-12 | プロサイ インコーポレイテッド | 酵母突然変異体において産生されるグリコシル化ポリペプチドおよびその使用方法 |
| US7622128B2 (en) * | 2005-12-13 | 2009-11-24 | University Of Washington | Porphyromonas gingivalis 1435/1449 LPS as an immune modulator |
| WO2007079193A2 (en) | 2005-12-30 | 2007-07-12 | Tti Ellebeau, Inc. | Iontophoretic systems, devices, and methods of delivery of active agents to biological interface |
| WO2008153541A1 (en) | 2006-09-26 | 2008-12-18 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| AU2007303608B2 (en) | 2006-09-29 | 2013-05-02 | Takeda Vaccines, Inc. | Norovirus vaccine formulations |
| CN101918028B (zh) | 2007-09-18 | 2015-01-07 | 莱戈赛特医药股份有限公司 | 赋予针对诺如病毒的保护性免疫应答的疫苗 |
| US20100266636A1 (en) * | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| US9415006B2 (en) * | 2008-05-23 | 2016-08-16 | The Regents Of The University Of Michigan | Immunogenic compositions comprising nanoemulsion and hepatitis B virus immunogen and methods of using the same |
| JP5852883B2 (ja) * | 2008-08-08 | 2016-02-03 | タケダ ワクチン，インコーポレイテッド | 交差反応性の増強のための複合カプシドアミノ酸配列を含むウイルス様粒子 |
| CN102223876A (zh) | 2008-09-26 | 2011-10-19 | 纳米生物公司 | 纳米乳剂治疗性组合物及其使用方法 |
| EP3124491B1 (en) | 2009-06-05 | 2019-10-30 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants and vaccine compositions as well as pharmaceutical compositions containing them |
| ES2566646T3 (es) * | 2009-06-16 | 2016-04-14 | The Regents Of The University Of Michigan | Vacunas en nanoemulsión |
| AU2012243039B2 (en) | 2011-04-08 | 2017-07-13 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
| DK3299030T3 (da) | 2011-07-11 | 2022-09-05 | Takeda Vaccines Inc | Parenterale norovirus-vaccineformuleringer |
| US20150190501A1 (en) | 2011-09-12 | 2015-07-09 | Imperial Innovations Limited | Methods and compositions for raising an immune response to hiv |
| EA034351B1 (ru) | 2012-05-16 | 2020-01-30 | Иммьюн Дизайн Корп. | Трехкомпонентная вакцина против впг-2 и способы ее применения |
| CN105209047B (zh) | 2013-04-18 | 2020-08-18 | 免疫设计股份有限公司 | 用于癌症治疗的gla单一疗法 |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| US9017698B2 (en) | 2013-09-25 | 2015-04-28 | Sequoia Sciences, Inc. | Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections |
| US10420833B2 (en) | 2014-05-19 | 2019-09-24 | Board Of Regents, The University Of Texas System | Combinatorial platform for the display of surface adjuvants and antigens |
| EP3069729A1 (en) | 2015-03-17 | 2016-09-21 | Sequoia Sciences, Inc. | Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections |
| WO2019175145A1 (en) | 2018-03-12 | 2019-09-19 | Janssen Vaccines & Prevention B.V. | Vaccines against urinary tract infections |
| US11446370B2 (en) | 2019-03-18 | 2022-09-20 | Janssen Pharmaceuticals, Inc. | Bioconjugates of E. coli o-antigen polysaccharides, methods of production thereof, and methods of use thereof |
| IL286467B1 (en) | 2019-03-18 | 2025-10-01 | Janssen Pharmaceuticals Inc | Methods for producing bioconjugates of E. COLI O-antigen polysaccharides, preparations thereof and methods for using them |
| WO2021067785A1 (en) | 2019-10-02 | 2021-04-08 | Janssen Vaccines & Prevention B.V | Staphylococcus peptides and methods of use |
| IL294445B2 (en) | 2020-01-16 | 2023-10-01 | Janssen Pharmaceuticals Inc | FIMH mutant, its preparations and their use |
| BR112023004819A2 (pt) | 2020-09-17 | 2023-04-18 | Janssen Pharmaceuticals Inc | Composições de vacinas multivalentes e seus usos |
| KR20250007029A (ko) | 2021-01-12 | 2025-01-13 | 얀센 파마슈티칼즈, 인코포레이티드 | FimH 돌연변이체, 이를 포함하는 조성물 및 이의 용도 |
| UY39710A (es) | 2021-04-01 | 2022-09-30 | Janssen Pharmaceuticals Inc | Producción de bioconjugados de o18 de e. coli |
| WO2022251455A1 (en) * | 2021-05-27 | 2022-12-01 | Revelation Biosciences, Inc. | Methods of treating or preventing allergies and chronic nasal congestion |
| WO2025058011A1 (ja) * | 2023-09-13 | 2025-03-20 | 国立大学法人大阪大学 | 経鼻投与用組成物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4436727A (en) * | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4436728A (en) * | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US5554372A (en) * | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
| US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US5068191A (en) * | 1989-08-31 | 1991-11-26 | The Biomembrane Institute | Purified histo-blood group a glycosyltransferase and antibodies thereto |
| FR2672496B3 (fr) * | 1990-07-18 | 1993-05-28 | Vacsyn France Sa | Compositions a base de substances hydrophobes, solubilisables dans un solvant aqueux, leur procede d'obtention, et leurs utilisations notamment dans le domaine pharmaceutique. |
| US5552141A (en) * | 1991-10-30 | 1996-09-03 | Ribi; Hans O. | Polymeric immunological adjuvants |
| US7014856B1 (en) * | 1993-01-22 | 2006-03-21 | Sloan-Kettering Institute For Cancer Research | Ganglioside-KLH conjugate vaccines plus OS-21 |
| DK0689454T4 (da) | 1993-03-23 | 2005-05-30 | Smithkline Beecham Biolog | Vaccinepræparater indeholdende 3-O-deacyleret monophosphoryl-lipid A |
| US5985309A (en) * | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
| US5855913A (en) | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| CN1259052A (zh) | 1997-04-01 | 2000-07-05 | 科里克萨有限公司 | 单磷酰基脂质a的水性免疫佐剂组合物 |
| CA2330610A1 (en) | 1998-05-07 | 1999-11-11 | Corixa Corporation | Adjuvant composition and methods for its use |
-
1999
- 1999-06-22 US US09/338,182 patent/US6491919B2/en not_active Expired - Lifetime
-
2000
- 2000-06-14 CA CA002376829A patent/CA2376829A1/en not_active Abandoned
- 2000-06-14 AT AT00944677T patent/ATE381344T1/de not_active IP Right Cessation
- 2000-06-14 DE DE60037514T patent/DE60037514T2/de not_active Expired - Fee Related
- 2000-06-14 AU AU58738/00A patent/AU775942B2/en not_active Ceased
- 2000-06-14 WO PCT/US2000/016384 patent/WO2000078353A2/en not_active Ceased
- 2000-06-14 JP JP2001504415A patent/JP2003502388A/ja active Pending
- 2000-06-14 EP EP00944677A patent/EP1194166B1/en not_active Expired - Lifetime
- 2000-06-14 ES ES00944677T patent/ES2296629T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1194166A2 (en) | 2002-04-10 |
| EP1194166B1 (en) | 2007-12-19 |
| DE60037514D1 (de) | 2008-01-31 |
| AU5873800A (en) | 2001-01-09 |
| ES2296629T3 (es) | 2008-05-01 |
| CA2376829A1 (en) | 2000-12-28 |
| US20020009456A1 (en) | 2002-01-24 |
| AU775942B2 (en) | 2004-08-19 |
| ATE381344T1 (de) | 2008-01-15 |
| US6491919B2 (en) | 2002-12-10 |
| WO2000078353A2 (en) | 2000-12-28 |
| WO2000078353A3 (en) | 2001-03-15 |
| JP2003502388A (ja) | 2003-01-21 |
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| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |