DE60035996D1 - Diätetisches kalzium als ergänzung zu vitamin d verbindungen bei der behandlung von multipler sklerose - Google Patents

Diätetisches kalzium als ergänzung zu vitamin d verbindungen bei der behandlung von multipler sklerose

Info

Publication number
DE60035996D1
DE60035996D1 DE60035996T DE60035996T DE60035996D1 DE 60035996 D1 DE60035996 D1 DE 60035996D1 DE 60035996 T DE60035996 T DE 60035996T DE 60035996 T DE60035996 T DE 60035996T DE 60035996 D1 DE60035996 D1 DE 60035996D1
Authority
DE
Germany
Prior art keywords
multiple sclerosis
vitamin
calcium
dietetic
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60035996T
Other languages
English (en)
Other versions
DE60035996T2 (de
Inventor
Hector F Deluca
Margherite T Cantorna
Jean Humpal-Winter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Application granted granted Critical
Publication of DE60035996D1 publication Critical patent/DE60035996D1/de
Publication of DE60035996T2 publication Critical patent/DE60035996T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60035996T 1999-07-08 2000-06-23 Diätetisches kalzium als ergänzung zu vitamin d verbindungen bei der behandlung von multipler sklerose Expired - Fee Related DE60035996T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/349,528 US6479474B2 (en) 1999-07-08 1999-07-08 Dietary calcium as a supplement to vitamin D compound treatment of multiple sclerosis
US349528 1999-07-08
PCT/US2000/017323 WO2001003704A1 (en) 1999-07-08 2000-06-23 Dietary calcium as a supplement to vitamin d compound treatment of multiple sclerosis

Publications (2)

Publication Number Publication Date
DE60035996D1 true DE60035996D1 (de) 2007-09-27
DE60035996T2 DE60035996T2 (de) 2008-05-15

Family

ID=23372774

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60035996T Expired - Fee Related DE60035996T2 (de) 1999-07-08 2000-06-23 Diätetisches kalzium als ergänzung zu vitamin d verbindungen bei der behandlung von multipler sklerose

Country Status (8)

Country Link
US (3) US6479474B2 (de)
EP (1) EP1196174B1 (de)
JP (1) JP2003504337A (de)
AT (1) ATE369864T1 (de)
AU (1) AU5634500A (de)
DE (1) DE60035996T2 (de)
DK (1) DK1196174T3 (de)
WO (1) WO2001003704A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7566696B2 (en) * 2002-09-05 2009-07-28 Wisconsin Alumni Research Foundation Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis
JP4469794B2 (ja) 2003-02-25 2010-05-26 神戸天然物化学株式会社 ビタミンｄ誘導体を合成するための新規な中間体
WO2004091573A1 (en) * 2003-03-04 2004-10-28 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and alphacalcidol for the treatment of multiple sclerosis
US7198653B2 (en) 2003-07-31 2007-04-03 Delavau Llc Calcium carbonate granulation
ATE537834T1 (de) * 2003-08-20 2012-01-15 Wisconsin Alumni Res Found 2-methylen-19-nor-vitamin d2-verbindungen
US20050080109A1 (en) * 2003-10-09 2005-04-14 Papas Andreas M. Gamma-tocopherol and gamma-tocotrienol therapy for multiple sclerosis
US20060195352A1 (en) * 2005-02-10 2006-08-31 David Goldberg Method and system for demand pricing of leads
WO2006086613A2 (en) * 2005-02-11 2006-08-17 Wisconsin Alumni Research Foundation 2-METHYLENE-19-NOR- (20S-24S) - 1α, 25-D IHYDROXYVITAMIN-D2
JP5036565B2 (ja) * 2005-02-11 2012-09-26 ウイスコンシン アラムニ リサーチ ファンデーション ２−メチレン−１９−ノル−（２０Ｓ−２４エピ）−１α，２５−ジヒドロキシビタミン−Ｄ２
JP2008530121A (ja) * 2005-02-14 2008-08-07 ウイスコンシン アラムナイ リサーチ フオンデーシヨン 多発性硬化症を治療および予防するためのカルシトニンおよびカルシトニン様ペプチド類の使用
CN101365494A (zh) * 2005-10-05 2009-02-11 贝希尔治疗学股份有限公司 治疗自身免疫性疾病的组合物和方法
US20100048679A1 (en) * 2006-06-13 2010-02-25 Bayhill Therapeutics, Inc. Polynucleotide therapy
US9138414B1 (en) 2006-09-15 2015-09-22 Delavau Llc Calcium supplement having enhanced absorption

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4279826A (en) 1980-09-22 1981-07-21 Wisconsin Alumni Research Foundation 23,25-Dihydroxyvitamin D3
US4307025A (en) 1981-02-17 1981-12-22 Wisconsin Alumni Research Foundation 1α, 25-dihydroxy-2β-fluorovitamin D3
US4448721A (en) 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
US5036061A (en) 1983-05-09 1991-07-30 Deluca Hector F Process for the preparation of 1 alpha,25-dihydroxylated vitamin D2 and related compounds
US4500460A (en) 1983-08-18 1985-02-19 Wisconsin Alumni Research Foundation 23,23-Difluoro-25-hydroxy-vitamin D3 and process for preparing same
US4502991A (en) 1983-08-18 1985-03-05 Wisconsin Alumni Research Foundation 23,23-Difluoro-1α,25-dihydroxy-vitamin D3
US4769181A (en) 1983-11-07 1988-09-06 Wisconsin Alumni Research Foundation 1,25-dihydroxyvitamin D2 compounds
US4505906A (en) 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4588528A (en) 1984-05-31 1986-05-13 Wisconsin Alumni Research Foundation 1,24-dihydroxy-Δ22 -vitamin D3 and process for preparing same
US4594192A (en) 1985-03-20 1986-06-10 Wisconsin Alumni Research Foundation 2α-fluorovitamin D3
IL78342A (en) * 1985-04-04 1991-06-10 Gen Hospital Corp Pharmaceutical composition for treatment of osteoporosis in humans comprising a parathyroid hormone or a fragment thereof
US4619920A (en) 1985-09-16 1986-10-28 Wisconsin Alumni Research Foundation 26,26,26,27,27-pentafluoro-1α-hydroxy-27-methoxyvitamin D3
JPS63104926A (ja) 1986-10-21 1988-05-10 Teijin Ltd 老年性痴呆症治療又は予防剤
CA1333616C (en) 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
US4973584A (en) 1989-03-09 1990-11-27 Deluca Hector F Novel 1α-hydroxyvitamin D2 epimer and derivatives
US5260290A (en) 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
JP2845342B2 (ja) 1990-04-28 1999-01-13 大正製薬株式会社 ビタミンｄ▲下３▼誘導体含有固形製剤組成物
JPH07502012A (ja) 1991-05-28 1995-03-02 ザ、プロクター、エンド、ギャンブル、カンパニー カルシウム、微量ミネラル、ビタミンｄ及び薬物療法剤組合せ
US5260199A (en) 1991-07-30 1993-11-09 Wisconsin Alumni Research Foundation Method of producing 1,25-dihydroxyvitamin D3 receptor protein
DE69214617T2 (de) 1991-12-26 1997-05-28 Wisconsin Alumni Res Found 26,27-Dimethylen-1-Alpha, 25-Dihydroxyvitamin-D2 und 26,27-Dihydroxyvitamin-D2 und Verfahren zu ihrer Herstellung
AU666529B2 (en) 1992-04-24 1996-02-15 Wisconsin Alumni Research Foundation Method of treating osteoporosis with 1 alpha, 24 (R)-dihydroxy-22 (E)-dehydro-vitamin D3
TW272187B (de) 1992-05-20 1996-03-11 Hoffmann La Roche
ES2091515T3 (es) 1992-05-20 1996-11-01 Hoffmann La Roche Analogos fluorados de la vitamina d3.
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
US5371249A (en) 1993-05-11 1994-12-06 Wisconsin Alumni Research Foundation Iodo vitamin D3 compounds and method for preparing same
US5380720A (en) 1993-05-11 1995-01-10 Wisconsin Alumni Research Foundation Iodo vitamin D3 compounds and method for preparing same
EP0972762B1 (de) 1993-07-09 2003-10-01 Laboratoire Theramex Neue strukturelle Vitamin D Derivate
US5373004A (en) 1993-11-24 1994-12-13 Wisconsin Alumni Research Foundation 26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds
IL115241A (en) * 1994-09-26 2000-08-31 American Cyanamid Co Calcium dietary supplement
US5716946A (en) 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
DE19710054A1 (de) 1997-03-12 1998-09-17 Merck Patent Gmbh Pharmazeutische Zubereitung
EP0980354B1 (de) 1997-04-28 2002-06-19 F. Hoffmann-La Roche Ag Vitamin d3 analoga mit bis-c-20-seitenketten
US6100294A (en) 1997-05-16 2000-08-08 Women And Infants Hospital Cyclic ether vitamin D3 compounds, 1α(OH) 3-epi-vitamin D3 compounds and uses thereof
US6673782B2 (en) * 1999-04-29 2004-01-06 Wisconsin Alumni Research Foundation Treatment of systemic lupus erythematosis

Also Published As

Publication number Publication date
DK1196174T3 (da) 2007-12-27
DE60035996T2 (de) 2008-05-15
ATE369864T1 (de) 2007-09-15
US6479474B2 (en) 2002-11-12
US20020016313A1 (en) 2002-02-07
EP1196174A1 (de) 2002-04-17
US20030207847A1 (en) 2003-11-06
JP2003504337A (ja) 2003-02-04
WO2001003704A1 (en) 2001-01-18
EP1196174B1 (de) 2007-08-15
AU5634500A (en) 2001-01-30
US20030022873A1 (en) 2003-01-30

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee