DE60035365T2 - Granulate von arzneistoffsalzen mit hydrolisierter cellulose - Google Patents

Granulate von arzneistoffsalzen mit hydrolisierter cellulose Download PDF

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Publication number
DE60035365T2
DE60035365T2 DE60035365T DE60035365T DE60035365T2 DE 60035365 T2 DE60035365 T2 DE 60035365T2 DE 60035365 T DE60035365 T DE 60035365T DE 60035365 T DE60035365 T DE 60035365T DE 60035365 T2 DE60035365 T2 DE 60035365T2
Authority
DE
Germany
Prior art keywords
ibuprofen
pharmaceutically active
slurry
active agent
hydrolyzed cellulose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60035365T
Other languages
German (de)
English (en)
Other versions
DE60035365D1 (de
Inventor
David F. Pennington ERKOBONI
Ronald S. Somerset VLADYKA
Christopher A. Chalfont SWERIDUK
Andrew J. New Egypt FAVARA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RP Scherer Technologies LLC
Original Assignee
RP Scherer Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RP Scherer Technologies LLC filed Critical RP Scherer Technologies LLC
Publication of DE60035365D1 publication Critical patent/DE60035365D1/de
Application granted granted Critical
Publication of DE60035365T2 publication Critical patent/DE60035365T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60035365T 1999-09-29 2000-09-26 Granulate von arzneistoffsalzen mit hydrolisierter cellulose Expired - Fee Related DE60035365T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15654799P 1999-09-29 1999-09-29
US156547P 1999-09-29
PCT/US2000/026340 WO2001022939A1 (fr) 1999-09-29 2000-09-26 Granulations par cellulose hydrolyzee de sels de medicaments
US669533 2000-09-26
US09/669,533 US6596312B1 (en) 1999-09-29 2000-09-26 Hydrolyzed cellulose granulations of salts of drugs

Publications (2)

Publication Number Publication Date
DE60035365D1 DE60035365D1 (de) 2007-08-09
DE60035365T2 true DE60035365T2 (de) 2008-02-28

Family

ID=26853293

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60035365T Expired - Fee Related DE60035365T2 (de) 1999-09-29 2000-09-26 Granulate von arzneistoffsalzen mit hydrolisierter cellulose

Country Status (12)

Country Link
US (2) US6596312B1 (fr)
EP (1) EP1233755B1 (fr)
AR (1) AR025879A1 (fr)
AT (1) ATE365541T1 (fr)
AU (1) AU777415B2 (fr)
CA (1) CA2386312A1 (fr)
DE (1) DE60035365T2 (fr)
DK (1) DK1233755T3 (fr)
ES (1) ES2288872T3 (fr)
PT (1) PT1233755E (fr)
TW (1) TWI236913B (fr)
WO (1) WO2001022939A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US6705028B2 (en) * 2001-09-12 2004-03-16 Honda Giken Kogyo Kabushiki Kaisha Self-propelled snowplow vehicle
AU2002335046A1 (en) * 2001-10-19 2003-05-06 Inhale Therapeutic Systems, Inc. The use of proton sequestering agents in drug formulations
WO2003035028A1 (fr) * 2001-10-19 2003-05-01 Nektar Therapeutics Modulation de la densite de charge pour ameliorer les caracteristiques de proteines sechees par pulverisation
US8025899B2 (en) * 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
US20070077297A1 (en) 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
WO2007071240A1 (fr) 2005-12-23 2007-06-28 Niro A/S Installation de production et processus pour produire des comprimés
US7582679B2 (en) * 2006-02-03 2009-09-01 Pharmaceutics International Incorporated Compositions containing solid ibuprofen concentrates and methods of making solid ibuprofen concentrates
US7749537B2 (en) * 2006-12-04 2010-07-06 Scolr Pharma, Inc. Method of forming a tablet
US20090104236A1 (en) * 2007-10-18 2009-04-23 Pharmaceutics International, Inc. Pharmaceutical solid hybrids

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL224413A (fr) 1957-01-28
US3111513A (en) 1960-01-13 1963-11-19 Fmc Corp Oxidation derivatives of cellulose crystallite aggregates
GB8528195D0 (en) * 1985-11-15 1985-12-18 Boots Co Plc Therapeutic compositions
IT1197038B (it) * 1986-08-01 1988-11-25 Zambon Spa Composizione farmaceutica ad attivita' analgesica
US4859704A (en) * 1987-10-15 1989-08-22 Oratech Pharmaceutical Development Corporation Water soluble ibuprofen compositions and methods of making them
CA2126441C (fr) 1991-12-30 1999-12-21 David F. Erkoboni Composition de spheronisation a base de cellulose microcristallisee
US5585115A (en) 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US5858409A (en) * 1996-04-17 1999-01-12 Fmc Corporation Hydrolyzed cellulose granulations for pharmaceuticals
ES2248850T3 (es) * 1996-05-20 2006-03-16 G.D. Searle Llc. Formulaciones farmaceuticas que contienen sales de potasiom sodio y tris de oxaprozina.
US5712310A (en) 1996-06-14 1998-01-27 Alpharma Uspd, Inc. Suspension of substantially water-insoluble drugs and methods of their manufacture
IT1301966B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica

Also Published As

Publication number Publication date
US6596312B1 (en) 2003-07-22
AU7714600A (en) 2001-04-30
AU777415B2 (en) 2004-10-14
EP1233755A1 (fr) 2002-08-28
US20040081701A1 (en) 2004-04-29
ES2288872T3 (es) 2008-02-01
ATE365541T1 (de) 2007-07-15
DE60035365D1 (de) 2007-08-09
PT1233755E (pt) 2007-07-30
EP1233755A4 (fr) 2004-02-04
WO2001022939A1 (fr) 2001-04-05
EP1233755B1 (fr) 2007-06-27
DK1233755T3 (da) 2007-10-29
CA2386312A1 (fr) 2001-04-05
AR025879A1 (es) 2002-12-18
TWI236913B (en) 2005-08-01

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee