DE60034476T2 - Topische nasenbehandlung mit desloratadin und mometason furoat - Google Patents

Topische nasenbehandlung mit desloratadin und mometason furoat Download PDF

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Publication number
DE60034476T2
DE60034476T2 DE60034476T DE60034476T DE60034476T2 DE 60034476 T2 DE60034476 T2 DE 60034476T2 DE 60034476 T DE60034476 T DE 60034476T DE 60034476 T DE60034476 T DE 60034476T DE 60034476 T2 DE60034476 T2 DE 60034476T2
Authority
DE
Germany
Prior art keywords
desloratadine
mometasone furoate
topical
nasal
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60034476T
Other languages
German (de)
English (en)
Other versions
DE60034476D1 (de
Inventor
Stephen J. Mendham ANDRZEJEWSKI
William West Paterson KREUTNER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DE60034476D1 publication Critical patent/DE60034476D1/de
Application granted granted Critical
Publication of DE60034476T2 publication Critical patent/DE60034476T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60034476T 1999-10-08 2000-10-05 Topische nasenbehandlung mit desloratadin und mometason furoat Expired - Lifetime DE60034476T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41508399A 1999-10-08 1999-10-08
US415083 1999-10-08
PCT/US2000/027463 WO2001026658A2 (en) 1999-10-08 2000-10-05 Topical nasal treatment using desloratadine

Publications (2)

Publication Number Publication Date
DE60034476D1 DE60034476D1 (de) 2007-05-31
DE60034476T2 true DE60034476T2 (de) 2008-01-03

Family

ID=23644317

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60034476T Expired - Lifetime DE60034476T2 (de) 1999-10-08 2000-10-05 Topische nasenbehandlung mit desloratadin und mometason furoat

Country Status (9)

Country Link
EP (1) EP1227812B1 (enExample)
JP (3) JP2003511417A (enExample)
AR (1) AR025964A1 (enExample)
AT (1) ATE359784T1 (enExample)
AU (1) AU7859800A (enExample)
CA (1) CA2383970A1 (enExample)
DE (1) DE60034476T2 (enExample)
ES (1) ES2284531T3 (enExample)
WO (1) WO2001026658A2 (enExample)

Families Citing this family (37)

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Publication number Priority date Publication date Assignee Title
WO2003101434A2 (en) * 2001-12-21 2003-12-11 Sampad Bhattacharya Intranasal pharmaceutical compositions comprising an antihistamine and a leukotriene inhibitor
TR200201343A2 (tr) * 2002-05-17 2003-12-22 Orva İlaç Sanayi̇ Ve Ti̇caret A. Ş. Kortikosteroid ve antiseptik içeren farmasötik bileşim
MXPA05005044A (es) * 2002-11-12 2005-07-01 Alcon Inc El uso de un agente antialergico y un esteroide para tratar rinitis alergica.
US7544192B2 (en) 2003-03-14 2009-06-09 Sinexus, Inc. Sinus delivery of sustained release therapeutics
WO2004082589A2 (en) * 2003-03-20 2004-09-30 Ranbaxy Laboratories Limited Nasally administrable, bioavailable pharmaceutical composition of loratadine
US20050192261A1 (en) * 2003-09-15 2005-09-01 Jost-Price Edward R. Methods and reagents for the treatment of immunoinflammatory disorders
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
EP1827499A4 (en) 2004-11-24 2010-03-17 Medpointe Healthcare Inc COMPOSITIONS COMPRISING AZELASTIN AND METHODS OF USE
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
CN101189016B (zh) 2005-04-04 2013-03-27 因特尔赛克特耳鼻喉公司 治疗鼻窦病症的装置
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
EP2851064A3 (en) * 2006-07-11 2015-08-05 Roy C. Levitt Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors
DE102006034883A1 (de) * 2006-07-25 2008-01-31 Hermal Kurt Herrmann Gmbh & Co. Ohg Pharmazeutische Zusammensetzung enthaltend Mometasonfuroat
EP2083798A1 (en) * 2006-10-19 2009-08-05 Cipla Limited Pharmaceutical compositions and nasal spray incorporating anhydrous mometasone furoate
CA2709901C (en) 2007-12-18 2022-05-10 Intersect Ent, Inc. Self-expanding devices and methods therefor
EP2320832A4 (en) 2008-08-01 2015-07-29 Intersect Ent Inc METHODS AND DEVICES FOR CRIMPING SELF-DILATABLE DEVICES
KR101099826B1 (ko) 2009-02-16 2011-12-27 서울대학교산학협력단 항알러지성 약물을 활성성분으로 함유하는 비강투여용 액상제제
CA3001814C (en) 2009-05-15 2020-12-22 Intersect Ent, Inc. Expandable devices and methods therefor
WO2011141929A2 (en) 2010-05-11 2011-11-17 Cadila Healthcare Limited Aqueous pharmaceutical compositions of fluticasone and olopatadine
FR2970180B1 (fr) * 2011-01-06 2013-08-02 Substipharm Dev Procede de preparation de suspensions aqueuses pharmaceutiques comprenant un medicament efficace dans le traitement des rhinites
DE112011105633T5 (de) 2011-09-21 2014-08-28 Mitsubishi Electric Corp. Siliziumkarbidhalbleitervorrichtung und Verfahren zu ihrer Herstellung
AU2014236729B2 (en) 2013-03-14 2018-11-22 Intersect Ent, Inc. Systems, devices, and method for treating a sinus condition
PH12016500433B1 (en) 2013-09-13 2023-03-01 Glenmark Pharmaceuticals Ltd Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
US9370483B2 (en) 2013-09-13 2016-06-21 Glenmark Specialty S.A. Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
US9937189B2 (en) 2013-09-13 2018-04-10 Glenmark Specialty S.A. Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
US10758550B2 (en) 2013-10-04 2020-09-01 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
CN112773808A (zh) 2013-10-04 2021-05-11 格兰马克专业公司 使用莫米松和奥洛他定的组合治疗过敏性鼻炎
US10016443B2 (en) 2013-10-04 2018-07-10 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
US10548907B2 (en) 2013-10-04 2020-02-04 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
US10653661B2 (en) 2013-10-04 2020-05-19 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
US11679210B2 (en) 2014-10-03 2023-06-20 Glenmark Specialty S.A. Dispensing device and pharmaceutical composition for the treatment of rhinitis
US20160120928A1 (en) * 2014-11-03 2016-05-05 Zent, Inc. Nasal spray
EP3331498B1 (en) * 2015-08-04 2020-03-11 WindStar Medical GmbH A nasal composition
CN106619504A (zh) * 2016-11-10 2017-05-10 北京万全德众医药生物技术有限公司 一种地氯雷他定口服滴剂及其制备方法
ES3017701T3 (en) * 2018-02-23 2025-05-13 Glenmark Specialty Sa Treatment of allergic rhinitis in pediatric subjects using a combination of mometasone and olopatadine
US12303635B2 (en) 2018-04-16 2025-05-20 Glenmark Specialty S.A. Dispensing device and pharmaceutical composition for the treatment of rhinitis
JP7337791B2 (ja) * 2018-06-22 2023-09-04 参天製薬株式会社 デスロラタジン又はその塩を含有する医薬組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0656206T3 (da) * 1991-06-10 2001-10-08 Schering Corp Aerosolformuleringer uden chlorfluorcarbonforbindelser
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
US5595997A (en) * 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
EP0780127A1 (en) * 1995-12-19 1997-06-25 The Procter & Gamble Company A nasal spray containing a steroid and a antihistamine
JPH11511758A (ja) * 1996-06-04 1999-10-12 ザ、プロクター、エンド、ギャンブル、カンパニー 鼻腔用ステロイドと抗ヒスタミン剤を含む鼻腔内噴霧薬
US5939426A (en) * 1997-02-28 1999-08-17 Sepracor Inc. Methods for treating urinary incontinence using descarboethoxyloratadine
JP2001510485A (ja) * 1999-03-01 2001-07-31 シェーリング コーポレイション アトピー性皮膚炎、血管性浮腫および他の障害を抗ヒスタミン薬およびグルココルチコイドを用いて処置するための組成物および方法

Also Published As

Publication number Publication date
AU7859800A (en) 2001-04-23
AR025964A1 (es) 2002-12-26
ES2284531T3 (es) 2007-11-16
DE60034476D1 (de) 2007-05-31
JP2003511417A (ja) 2003-03-25
WO2001026658A3 (en) 2002-02-21
ATE359784T1 (de) 2007-05-15
CA2383970A1 (en) 2001-04-19
JP2007106777A (ja) 2007-04-26
WO2001026658A2 (en) 2001-04-19
JP2008056698A (ja) 2008-03-13
EP1227812B1 (en) 2007-04-18
EP1227812A2 (en) 2002-08-07

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