DE60027734D1 - Chirale phosphine, deren komplexe mit übergangsmetallen und deren verwendung in asymmetrischen synthesereaktionen - Google Patents

Chirale phosphine, deren komplexe mit übergangsmetallen und deren verwendung in asymmetrischen synthesereaktionen

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Publication number
DE60027734D1
DE60027734D1 DE60027734T DE60027734T DE60027734D1 DE 60027734 D1 DE60027734 D1 DE 60027734D1 DE 60027734 T DE60027734 T DE 60027734T DE 60027734 T DE60027734 T DE 60027734T DE 60027734 D1 DE60027734 D1 DE 60027734D1
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Prior art keywords
chiral
asymmetric
ligands
complexes
transition metals
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Expired - Lifetime
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DE60027734T
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DE60027734T2 (de
Inventor
Xumu Zhang
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Penn State Research Foundation
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Penn State Research Foundation
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Publication of DE60027734T2 publication Critical patent/DE60027734T2/de
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    • B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
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Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812638B1 (fr) * 2000-08-03 2003-04-25 Ppg Sipsy Utilisation de diphosphines chirales comme ligands optiquement actifs pour la preparation de complexes diphosphino-metalliques, les complexes ainsi obtenus et les procedes de catalyse asymetrique les mettant en oeuvre
US6350819B1 (en) 2000-10-27 2002-02-26 Union Carbide Chemicals & Plastics Technology Corporation Dendritic macromolecules for metal-ligand catalyzed processes
AU2002342362A1 (en) * 2001-11-15 2003-05-26 Sasol Technology (Pty) Ltd Preparation of derivatives of a group 5a element
US7419933B2 (en) 2002-03-11 2008-09-02 Japan Science And Technology Agency Practical chiral zirconium catalyst
JP4148702B2 (ja) 2002-06-04 2008-09-10 高砂香料工業株式会社 新規なジホスフィン化合物、その製造中間体、該化合物を配位子とする遷移金属錯体並びに該錯体を含む不斉水素化触媒
JP4218261B2 (ja) * 2002-06-11 2009-02-04 ダイキン工業株式会社 ポンプユニット
GB0228018D0 (en) * 2002-11-30 2003-01-08 Lucite Int Uk Ltd Carbonylation of ester
CN1681591B (zh) * 2002-09-12 2012-04-18 卢西特国际英国有限公司 催化剂体系
US6878838B2 (en) 2003-03-24 2005-04-12 The University Of North Carolina At Chapel Hill Chiral porous metal phosphonates for heterogeneous asymmetric catalysis
WO2004084834A2 (en) * 2003-03-24 2004-10-07 The University Of North Carolina At Chapel Hill Chiral porous metal phosphonates for heterogeneous asymmetric catalysis
US7396947B2 (en) * 2003-06-13 2008-07-08 Lanxess Deutschland Gmbh Chiral ligands for application in asymmetric syntheses
JP2007516197A (ja) 2003-07-03 2007-06-21 ルーサイト インターナショナル ユーケー リミテッド エチレン性不飽和化合物のヒドロホルミル化方法
US7094725B2 (en) * 2003-07-11 2006-08-22 The Hong Kong Polytechnic University Biphenyldiphosphine compounds
DE10342672A1 (de) 2003-09-16 2005-04-21 Bayer Chemicals Ag Chirale Phosphane zur Verwendung in asymmetrischen Synthesen
GB0403592D0 (en) 2004-02-18 2004-03-24 Lucite Int Uk Ltd A catalyst system
CA2563617A1 (en) * 2004-04-20 2005-11-03 Rnd Pharmaceuticals Pharmaceutical compositions and methods of use of lipophilic, silicon-substituted, cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs and derivatives
GB0411951D0 (en) * 2004-05-28 2004-06-30 Lucite Int Uk Ltd Carbonylation of ester
DE102005030400A1 (de) * 2005-06-27 2006-12-28 Archimica Gmbh Verfahren zur Herstellung von Arylaminen, Arylethern und Arylthioethern
GB0516556D0 (en) * 2005-08-12 2005-09-21 Lucite Int Uk Ltd Improved catalyst system
KR20080077201A (ko) 2005-11-17 2008-08-21 루사이트 인터내셔널 유케이 리미티드 에틸렌성 불포화 화합물의 카르보닐화
JP4621918B2 (ja) * 2005-12-09 2011-02-02 国立大学法人 千葉大学 新規不斉イリジウム触媒の製造方法とこれらを用いる光学活性β−ヒドロキシ−α−アミノ酸誘導体の製造方法
EP1960409B2 (de) * 2005-12-15 2023-08-02 The Penn State Research Foundation Tetraphosphorliganden für katalytische hydroformylierung und entsprechende reaktionen
CN100349880C (zh) * 2005-12-29 2007-11-21 上海交通大学 2,2’,6,6’－四噁唑啉联苯配体及其制备方法
WO2007073699A1 (fr) * 2005-12-29 2007-07-05 Shanghai Jiaotong University Ligands chiraux de 1,1'-biphenyle axial 5,5'-lie et procedes de preparation de ceux-ci
CN100348597C (zh) * 2005-12-29 2007-11-14 上海交通大学 5，5’位连接的1, 1’－联苯类轴手性配体的合成方法
JP5116694B2 (ja) * 2006-01-19 2013-01-09 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 不均一キラル触媒
GB0607494D0 (en) 2006-04-13 2006-05-24 Lucite Int Uk Ltd Metal complexes
CA2671409C (en) * 2006-12-02 2016-07-26 Lucite International Uk Limited Novel carbonylation ligands and their use in the carbonylation of ethylenically unsaturated compounds
GB0625518D0 (en) * 2006-12-21 2007-01-31 Lucite Int Uk Ltd Carbonylation of conjugated dienes
EP2297042B1 (de) * 2008-03-19 2013-07-10 Bial-Portela & CA, S.A. Katalytische asymmetrische hydrierung
GB0812297D0 (en) * 2008-07-04 2008-08-13 Lucite Int Uk Ltd Novel carbonylation ligand sand thier use of in the carbonylation of ethylenically unsaturated compounds
JP5011262B2 (ja) * 2008-10-31 2012-08-29 高砂香料工業株式会社 ホスフィン化合物
JP5544756B2 (ja) * 2009-05-18 2014-07-09 東ソー株式会社 ホスフィン化合物及び該ホスフィン化合物と遷移金属化合物からなる触媒
FR2952638A1 (fr) 2009-11-17 2011-05-20 Univ Strasbourg Procede de phosphination catalytique double ou triple de composes di, tri ou tetrahalobiaryles, intermediaires employes, composes obtenus et leurs utilisations
GB201000078D0 (en) 2010-01-05 2010-02-17 Lucite Int Uk Ltd Process for the carbonylation of ethylenically unsaturated compounds, novel carbonylation ligands and catalyst systems incorporatng such ligands
JP5639199B2 (ja) * 2010-03-12 2014-12-10 カウンシル・オヴ・サイエンティフィック・アンド・インダストリアル・リサーチ 不斉ニトロアルドール反応のためのキラル不均一触媒
US9530571B2 (en) 2011-11-18 2016-12-27 Adeka Corporation Compound and support material supporting this novel compound
CN102592837B (zh) * 2012-03-12 2014-01-15 河北师范大学 制备超级电容器用四氯合金属季铵盐掺杂聚苯胺电极的方法
GB201316410D0 (en) 2013-09-13 2013-10-30 Bial Portela & Ca Sa Processes for preparing peripherally-selective inhibitors of dopamine-?-hydroxylase and intermediates for use therein
CN105985469B (zh) * 2015-02-11 2018-07-10 中国石油天然气股份有限公司 聚丙烯催化剂及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0398132T3 (da) * 1989-05-18 1995-12-18 Hoffmann La Roche Phosphorforbindelser
DK0565975T3 (da) * 1992-04-16 1996-10-14 Hoffmann La Roche Fremgangsmåde til fremstilling af isoprenderivater
US5481008A (en) * 1993-09-13 1996-01-02 Hoffmann-La Roche Inc. Process for the preparation of optically active compounds
DE4422672A1 (de) * 1994-06-30 1996-01-04 Hoechst Ag Halogenierte Biphenyl-2,2'-diyl-bis-diphenylphosphine, ihre Herstellung und ihre Verwendung
IT1270082B (it) 1994-07-12 1997-04-28 Univ Degli Studi Milano Difosfine eteroaromatiche come leganti chirali, complessi tra dette difosfine e metalli di transizione ed impiego di detti complessi come catalizzatori chirali
DE69627834T2 (de) * 1995-02-24 2004-04-08 Nissan Chemical Industries, Ltd. Optisch aktiver zweizähniger phosphinligand-palladiumkomplex
JP3899542B2 (ja) * 1995-02-24 2007-03-28 日産化学工業株式会社 光学活性二座ホスフィン配位子パラジウム錯体
US5624128A (en) 1995-03-06 1997-04-29 Owens; Jesse L. Transport system for disabled people
US5852212A (en) * 1995-06-21 1998-12-22 Rolic Ag Process for preparation of optically active α-bromo and α-chlorocarboxylic compounds
JP3493266B2 (ja) * 1996-08-27 2004-02-03 高砂香料工業株式会社 新規な光学活性ジホスフィン化合物、該化合物を製造す る方法、該化合物を配位子とする遷移金属錯体並びに該 錯体を用いた光学活性体の製造方法
CA2290009A1 (en) * 1998-11-19 2000-05-19 Rhony Niklaus Aufdenblatten Chiral diphenyldiphosphines and d-8 metal complexes thereof
EP1060793B1 (de) * 1999-06-17 2005-06-15 Firmenich Sa Stereospezifische Isomerierung von Allylaminen unter Verwendung von immobilisierten chiralen Phospho-Liganden
JP2001131192A (ja) * 1999-10-29 2001-05-15 Takasago Internatl Corp 新規な光学活性ジホスフィン化合物、その製造中間体、該化合物を配位子とする遷移金属錯体並びに該錯体を含む不斉水素化触媒。

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JP2003509513A (ja) 2003-03-11
EP1214328B1 (de) 2006-05-03
AU7590600A (en) 2001-04-24
ATE324943T1 (de) 2006-06-15
CA2385421C (en) 2009-12-15
US6521769B1 (en) 2003-02-18
EP1214328A1 (de) 2002-06-19
EP1214328A4 (de) 2002-11-27
CA2385421A1 (en) 2001-03-29
JP4947866B2 (ja) 2012-06-06

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