DE60024353D1 - Verfahren zur Herstellung Antiosteoporicagenz - Google Patents

Verfahren zur Herstellung Antiosteoporicagenz

Info

Publication number
DE60024353D1
DE60024353D1 DE60024353T DE60024353T DE60024353D1 DE 60024353 D1 DE60024353 D1 DE 60024353D1 DE 60024353 T DE60024353 T DE 60024353T DE 60024353 T DE60024353 T DE 60024353T DE 60024353 D1 DE60024353 D1 DE 60024353D1
Authority
DE
Germany
Prior art keywords
osteoporic
agent
producing anti
preparation
analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60024353T
Other languages
English (en)
Other versions
DE60024353T2 (de
Inventor
Andrzej Robert Daniewski
Roumen Nikolaev Radinov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE60024353D1 publication Critical patent/DE60024353D1/de
Publication of DE60024353T2 publication Critical patent/DE60024353T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Epoxy Compounds (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
DE60024353T 1999-04-26 2000-04-19 Verfahren zur Herstellung Antiosteoporicagenz Expired - Lifetime DE60024353T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13094899P 1999-04-26 1999-04-26
US130948P 1999-04-26

Publications (2)

Publication Number Publication Date
DE60024353D1 true DE60024353D1 (de) 2006-01-05
DE60024353T2 DE60024353T2 (de) 2006-08-03

Family

ID=22447142

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60024353T Expired - Lifetime DE60024353T2 (de) 1999-04-26 2000-04-19 Verfahren zur Herstellung Antiosteoporicagenz

Country Status (12)

Country Link
US (1) US6255501B1 (de)
EP (1) EP1048661B1 (de)
JP (1) JP2000336094A (de)
KR (1) KR100697491B1 (de)
CN (1) CN1272494A (de)
AT (1) ATE311375T1 (de)
CA (1) CA2306573C (de)
DE (1) DE60024353T2 (de)
DK (1) DK1048661T3 (de)
ES (1) ES2251905T3 (de)
JO (1) JO2176B1 (de)
MX (1) MX221794B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004203436A1 (en) 2003-09-24 2005-04-14 Bioxell Spa Compound and use in treatment
CH698144B1 (fr) * 2003-09-24 2009-05-29 Bioxell Spa Analogue de la vitamine D3
US20090137828A1 (en) * 2005-08-18 2009-05-28 Bioxell S.P.A. Synthesis of 1A-Fluoro-25-Hydroxy-16-23E-Diene-26,27-Bishomo-20-Epi-Cholecalciferol
US20100009949A1 (en) * 2006-03-24 2010-01-14 Bioxell S.P.A. Novel method
ES2366077B2 (es) * 2010-03-30 2012-06-25 Universidade De Vigo Compuestos quirales, procedimientos de obtención y uso.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
US5872113A (en) * 1997-05-16 1999-02-16 Syntex (U.S.A.) Inc. Fluorinated vitamin D3 analogs
US8830885B2 (en) * 2008-08-21 2014-09-09 Qualcomm Incorporated Multichannel architecture for high throughput modems

Also Published As

Publication number Publication date
CA2306573A1 (en) 2000-10-26
JP2000336094A (ja) 2000-12-05
CN1272494A (zh) 2000-11-08
EP1048661A2 (de) 2000-11-02
EP1048661B1 (de) 2005-11-30
KR20010014811A (ko) 2001-02-26
KR100697491B1 (ko) 2007-03-20
JO2176B1 (en) 2003-04-23
DK1048661T3 (da) 2006-03-27
ATE311375T1 (de) 2005-12-15
US6255501B1 (en) 2001-07-03
DE60024353T2 (de) 2006-08-03
EP1048661A3 (de) 2002-10-09
CA2306573C (en) 2009-09-29
MXPA00003993A (es) 2002-03-08
ES2251905T3 (es) 2006-05-16
MX221794B (es) 2004-07-27

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Legal Events

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8364 No opposition during term of opposition