DE60015036D1 - Zwischenprodukte und ein Verfahren zur Herstellung von beta3-Adrenergischer Rezeptor-Agoniste - Google Patents
Zwischenprodukte und ein Verfahren zur Herstellung von beta3-Adrenergischer Rezeptor-AgonisteInfo
- Publication number
- DE60015036D1 DE60015036D1 DE60015036T DE60015036T DE60015036D1 DE 60015036 D1 DE60015036 D1 DE 60015036D1 DE 60015036 T DE60015036 T DE 60015036T DE 60015036 T DE60015036 T DE 60015036T DE 60015036 D1 DE60015036 D1 DE 60015036D1
- Authority
- DE
- Germany
- Prior art keywords
- beta3
- intermediates
- production
- receptor agonists
- adrenergic receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14541799P | 1999-07-23 | 1999-07-23 | |
| US145417P | 1999-07-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60015036D1 true DE60015036D1 (de) | 2004-11-25 |
| DE60015036T2 DE60015036T2 (de) | 2006-03-02 |
Family
ID=22513018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60015036T Expired - Fee Related DE60015036T2 (de) | 1999-07-23 | 2000-07-14 | Zwischenprodukte und ein Verfahren zur Herstellung von beta3-Adrenergischer Rezeptor-Agoniste |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6297382B1 (de) |
| EP (1) | EP1078924B1 (de) |
| JP (1) | JP2001048864A (de) |
| AT (1) | ATE280167T1 (de) |
| DE (1) | DE60015036T2 (de) |
| ES (1) | ES2228413T3 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2471646A1 (en) | 2002-02-27 | 2003-09-04 | Yong Tao | Processes and intermediates useful in preparing .beta.3-adrenergic receptor agonists |
| US6864268B2 (en) | 2002-02-27 | 2005-03-08 | Pfizer Inc. | β3 adrenergic receptor agonists |
| WO2003072573A1 (en) | 2002-02-27 | 2003-09-04 | Pfizer Products Inc. | Crystal forms of (r)-2-(2-(4-oxazol-4-yl-phenoxy)-ethylamino)-1-pyridin-3-yl-ethanol |
| EP1424079A1 (de) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Kombination eines beta-3-Rezeptoragonisten und eines Serotonin und/oder Norepinephrin-Wiederaufnahmeinhibitors |
| US7323462B2 (en) * | 2002-12-10 | 2008-01-29 | Pfizer Inc. | Morpholine dopamine agonists |
| GB0312832D0 (en) * | 2003-06-04 | 2003-07-09 | Pfizer Ltd | 2-amino-pyridine derivatives useful for the treatment of diseases |
| US7375100B2 (en) | 2003-06-04 | 2008-05-20 | Pfizer Inc | 2-amino-pyridine derivatives useful for the treatment of diseases |
| US20050113318A1 (en) * | 2003-07-31 | 2005-05-26 | Robinson Cynthia B. | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease |
| US20090285900A1 (en) * | 2003-07-31 | 2009-11-19 | Robinson Cynthia B | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease |
| US20050026884A1 (en) * | 2003-07-31 | 2005-02-03 | Robinson Cynthia B. | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease |
| EP1786762A2 (de) * | 2004-09-10 | 2007-05-23 | Theravance, Inc. | Amidin-substituierte arylanilinverbindungen |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5019578A (en) | 1987-11-27 | 1991-05-28 | Merck & Co., Inc. | β-adrenergic agonists |
| US5030640A (en) | 1989-01-05 | 1991-07-09 | Merck & Co., Inc. | Novel β-adrenergic agonists and pharmaceutical compositions thereof |
| EP0824519A1 (de) | 1995-05-10 | 1998-02-25 | Pfizer Inc. | Beta-adrenergische agonisten |
| AR003509A1 (es) | 1995-09-15 | 1998-08-05 | Merck & Co Inc | Sintesis de alfa-cloro o fluoro cetonas. |
| CA2270386C (en) * | 1996-11-14 | 2004-08-03 | Pfizer Inc. | Process for substituted pyridines |
| TW502032B (en) * | 1997-12-19 | 2002-09-11 | Bayer Ag | Novel sulfonamide substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
| US6090942A (en) * | 1998-10-15 | 2000-07-18 | Pfizer Inc. | Process and intermediates for a β3 -adrenergic receptor agonist |
-
2000
- 2000-07-14 AT AT00305987T patent/ATE280167T1/de not_active IP Right Cessation
- 2000-07-14 EP EP00305987A patent/EP1078924B1/de not_active Expired - Lifetime
- 2000-07-14 ES ES00305987T patent/ES2228413T3/es not_active Expired - Lifetime
- 2000-07-14 DE DE60015036T patent/DE60015036T2/de not_active Expired - Fee Related
- 2000-07-20 US US09/620,042 patent/US6297382B1/en not_active Expired - Fee Related
- 2000-07-24 JP JP2000222094A patent/JP2001048864A/ja active Pending
-
2001
- 2001-07-24 US US09/912,016 patent/US6441181B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1078924B1 (de) | 2004-10-20 |
| ATE280167T1 (de) | 2004-11-15 |
| US6297382B1 (en) | 2001-10-02 |
| DE60015036T2 (de) | 2006-03-02 |
| JP2001048864A (ja) | 2001-02-20 |
| US6441181B1 (en) | 2002-08-27 |
| EP1078924A1 (de) | 2001-02-28 |
| ES2228413T3 (es) | 2005-04-16 |
| US20020045757A1 (en) | 2002-04-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |