DE60013161T2 - Neue fucosylierte oligosaccharide und verfahren zu deren herstellung - Google Patents

Neue fucosylierte oligosaccharide und verfahren zu deren herstellung Download PDF

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Publication number
DE60013161T2
DE60013161T2 DE60013161T DE60013161T DE60013161T2 DE 60013161 T2 DE60013161 T2 DE 60013161T2 DE 60013161 T DE60013161 T DE 60013161T DE 60013161 T DE60013161 T DE 60013161T DE 60013161 T2 DE60013161 T2 DE 60013161T2
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DE
Germany
Prior art keywords
glcnac
monosaccharide
glc
oligosaccharides
fucosylated
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60013161T
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German (de)
English (en)
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DE60013161D1 (de
Inventor
Jari Natunen
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Glykos Finland Ltd
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Glykos Finland Ltd
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Publication of DE60013161T2 publication Critical patent/DE60013161T2/de
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Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Materials Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60013161T 1999-09-28 2000-09-21 Neue fucosylierte oligosaccharide und verfahren zu deren herstellung Expired - Lifetime DE60013161T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI992070 1999-09-28
FI19992070A FI19992070A7 (fi) 1999-09-28 1999-09-28 Uudet fukosyloidut oligosakkaridit ja menetelmä niiden valmistamiseksi
PCT/FI2000/000803 WO2001023398A1 (en) 1999-09-28 2000-09-21 Novel fucosylated oligosaccharides and process for their preparation

Publications (2)

Publication Number Publication Date
DE60013161D1 DE60013161D1 (de) 2004-09-23
DE60013161T2 true DE60013161T2 (de) 2005-12-29

Family

ID=8555359

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60013161T Expired - Lifetime DE60013161T2 (de) 1999-09-28 2000-09-21 Neue fucosylierte oligosaccharide und verfahren zu deren herstellung

Country Status (11)

Country Link
US (1) US6878819B1 (enExample)
EP (1) EP1228079B1 (enExample)
JP (1) JP2003510330A (enExample)
AT (1) ATE273987T1 (enExample)
AU (1) AU780370B2 (enExample)
CA (1) CA2385295A1 (enExample)
DE (1) DE60013161T2 (enExample)
FI (1) FI19992070A7 (enExample)
NZ (1) NZ518267A (enExample)
WO (1) WO2001023398A1 (enExample)
ZA (1) ZA200202184B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904581D0 (sv) * 1999-12-15 1999-12-15 A & Science Invest Ab A novel helicobacter pylori-binding substance and use thereof
FR2806077B1 (fr) * 2000-03-07 2004-01-30 Solvay Procede pour l'obtention d'un hydrofluoroalcane epure, hydrofluoroalcane epure, utilisation de l'hydrofluoroalcane et methode d'analyse d'un hydrofluoroalcane
DE10145193C1 (de) 2001-09-13 2003-03-13 Sachtler Gmbh & Co Kg Körpermontierbares Kameratragesystem mit einem multifunktionalen Verbund elektrischer Komponenten
WO2004065400A1 (en) * 2003-01-20 2004-08-05 Glykos Finland Oy Novel binding epitopes for helicobacter pylori and use thereof
JP5331293B2 (ja) * 2006-04-28 2013-10-30 公益財団法人野口研究所 多様性を表現するオリゴ糖またはその誘導体
US7800057B2 (en) * 2007-06-01 2010-09-21 Perkinelmer Health Sciences, Inc. Atmospheric pressure ion source performance enhancement
US7919746B2 (en) * 2007-10-16 2011-04-05 Perkinelmer Health Sciences, Inc. Atmospheric pressure ion source performance enhancement
JP5605541B2 (ja) * 2009-03-06 2014-10-15 国立大学法人埼玉大学 フコシルキトビオース誘導体の製造方法
PL2944690T3 (pl) * 2010-10-11 2018-05-30 Jennewein Biotechnologie Gmbh Nowe fukozylotransferazy i ich zastosowanie
ES2439507T3 (es) * 2011-01-20 2014-01-23 Jennewein Biotechnologie Gmbh Fucosiltransferasas novedosas y sus aplicaciones
US8999698B2 (en) 2011-03-31 2015-04-07 Novozymes Biologicals, Inc. Competitive and effective bacterial strains
ES2574957T3 (es) 2011-09-08 2016-06-23 Novozymes Bioag A/S Métodos de tratamiento de semillas
CA2848856C (en) 2011-09-14 2020-04-28 Novozymes Bioag A/S Use of lipochito-oligosaccharides and/or chito-oligosaccharides in combination with phosphate-solubilizing microorganisms to enhance plant growth
CN104066327A (zh) 2011-09-23 2014-09-24 诺维信生物农业公司 用于增强植物生长的脂壳寡糖组合和方法
EP2747567B1 (en) 2011-09-23 2016-11-16 Novozymes Bioag A/S Chitooligosaccharides and methods for use in enhancing soybean growth
EP2747558B1 (en) 2011-09-23 2018-01-03 Novozymes Bioag A/S Use of chitooligosaccharides in a method for enhancing plant growth
BR112014006912A2 (pt) 2011-09-23 2017-04-11 Novozymes Bioag As método para intensificar o crescimento de plantas de milho
AU2012351899B2 (en) 2011-12-16 2015-04-23 Novozymes Bioag A/S Bradyrhizobium strains
CN103484526A (zh) * 2012-06-14 2014-01-01 北京和信非凡生物技术有限公司 一种β-氨基己糖苷酶A酶活性检测方法、底物和试剂
CN103424500A (zh) * 2013-08-16 2013-12-04 浙江树人大学 离子色谱定性检测壳寡糖的方法及应用
AU2016383059B2 (en) 2015-12-28 2022-10-27 Monsanto Technology Llc Stable inoculant compositions and methods for producing same
KR20190076046A (ko) * 2016-11-10 2019-07-01 산도즈 아게 단백질 용액의 탈염 공정
CN115058465B (zh) * 2022-06-30 2025-03-07 山东大学 一种岩藻糖基化软骨素及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992016640A1 (en) 1991-03-18 1992-10-01 The Scripps Research Institute Oligosaccharide enzyme substrates and inhibitors: methods and compositions
US5374655A (en) * 1991-06-10 1994-12-20 Alberta Research Council Methods for the synthesis of monofucosylated oligosaccharides terminating in di-N-acetyllactosaminyl structures
US6319695B1 (en) * 1991-10-15 2001-11-20 The Scripps Research Insitute Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
US5922577A (en) * 1995-04-11 1999-07-13 Cytel Corporation Enzymatic synthesis of glycosidic linkages
WO1997003206A1 (en) * 1995-07-13 1997-01-30 Bioflexin Ab Method of producing derivatives of glc-beta 1-4glc-n-acetyl
US5972907A (en) 1997-10-31 1999-10-26 Health Research, Inc. Synthetic core 2-like branched structures containing GalNAc-lewisx and Neu5Acα2-3Galβ1-3GalNAc sequences as novel ligands for selectins

Also Published As

Publication number Publication date
AU7293000A (en) 2001-04-30
AU780370B2 (en) 2005-03-17
WO2001023398A1 (en) 2001-04-05
FI19992070L (fi) 2001-03-28
JP2003510330A (ja) 2003-03-18
FI19992070A7 (fi) 2001-03-29
CA2385295A1 (en) 2001-04-05
NZ518267A (en) 2003-10-31
US6878819B1 (en) 2005-04-12
ZA200202184B (en) 2003-05-28
DE60013161D1 (de) 2004-09-23
EP1228079B1 (en) 2004-08-18
ATE273987T1 (de) 2004-09-15
EP1228079A1 (en) 2002-08-07

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: GLYKOS FINLAND OY, HELSINKI, FI

8328 Change in the person/name/address of the agent

Representative=s name: VOSSIUS & PARTNER, 81675 MUENCHEN

8364 No opposition during term of opposition