DE60007345D1 - Basische monocyclische verbindungen mit nk-2 antagonistischer wirkung, verfahren zu ihrer herstellung, und sie enthaltende mittel - Google Patents

Basische monocyclische verbindungen mit nk-2 antagonistischer wirkung, verfahren zu ihrer herstellung, und sie enthaltende mittel

Info

Publication number
DE60007345D1
DE60007345D1 DE60007345T DE60007345T DE60007345D1 DE 60007345 D1 DE60007345 D1 DE 60007345D1 DE 60007345 T DE60007345 T DE 60007345T DE 60007345 T DE60007345 T DE 60007345T DE 60007345 D1 DE60007345 D1 DE 60007345D1
Authority
DE
Germany
Prior art keywords
production
antagonistic effect
monocyclic compounds
basic
basic monocyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60007345T
Other languages
English (en)
Other versions
DE60007345T2 (de
Inventor
Enzo Perrotta
Danilo Giannotti
Maria Altamura
Sandro Giuliani
Alberto Maggi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Menarini Ricerche SpA
Original Assignee
Menarini Ricerche SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche SpA filed Critical Menarini Ricerche SpA
Application granted granted Critical
Publication of DE60007345D1 publication Critical patent/DE60007345D1/de
Publication of DE60007345T2 publication Critical patent/DE60007345T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60007345T 1999-10-21 2000-10-17 Basische monocyclische verbindungen mit nk-2 antagonistischer wirkung, verfahren zu ihrer herstellung, und sie enthaltende mittel Expired - Fee Related DE60007345T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1999FI000217A IT1307809B1 (it) 1999-10-21 1999-10-21 Composti monociclici basici ad azione nk-2 antagonista, processi difabbricazione e formulazioni che li contengono.
ITFI990217 1999-10-21
PCT/EP2000/010181 WO2001029066A2 (en) 1999-10-21 2000-10-17 Basic monocyclic compounds having nk2 antagonist action, processes for their preparation, and formulations containing them

Publications (2)

Publication Number Publication Date
DE60007345D1 true DE60007345D1 (de) 2004-01-29
DE60007345T2 DE60007345T2 (de) 2004-11-11

Family

ID=11353095

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60007345T Expired - Fee Related DE60007345T2 (de) 1999-10-21 2000-10-17 Basische monocyclische verbindungen mit nk-2 antagonistischer wirkung, verfahren zu ihrer herstellung, und sie enthaltende mittel

Country Status (13)

Country Link
US (1) US7015196B1 (de)
EP (1) EP1224210B1 (de)
JP (1) JP2003512387A (de)
CN (1) CN1199987C (de)
AR (1) AR026209A1 (de)
AT (1) ATE256697T1 (de)
AU (1) AU7919900A (de)
CA (1) CA2388315A1 (de)
DE (1) DE60007345T2 (de)
ES (1) ES2211628T3 (de)
IT (1) IT1307809B1 (de)
PT (1) PT1224210E (de)
WO (1) WO2001029066A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE319703T1 (de) 2001-07-02 2006-03-15 Piperidinverbindungen, die sich als modulatoren der chemokinrezeptoraktivität eignen
GB0120461D0 (en) 2001-08-22 2001-10-17 Astrazeneca Ab Novel compounds
GB0122503D0 (en) 2001-09-18 2001-11-07 Astrazeneca Ab Chemical compounds
MY130373A (en) 2001-10-29 2007-06-29 Malesci Sas Linear basic compounds having nk-2 antagonist activity and formulations thereof
SE0200844D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0200843D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0300957D0 (sv) 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
ITFI20040221A1 (it) * 2004-10-27 2005-01-27 Guidotti & C Spa Composizioni farmaceutiche a base di nk2 antagonisti per uso pediatrico
ES2397418T3 (es) 2005-07-21 2013-03-06 Astrazeneca Ab Derivados de piperidina
EP1976495A2 (de) * 2006-01-06 2008-10-08 Aarhus Universitet Auf den serotonin-transporter wirkende verbindungen
UY38485A (es) * 2018-11-27 2020-06-30 Novartis Ag Compuestos tetrámeros cíclicos como inhibidores de proproteína convertasa subtilisina/kexina tipo 9 (pcsk9), método de tratamiento, uso y su preparación

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8000470A (nl) 1980-01-25 1981-01-30 Akzo Nv Zonnecollector met een vloeistof opnemende laag.
US5187156A (en) * 1988-03-16 1993-02-16 Fujisawa Pharmaceutical Co., Ltd. Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same
EP0606222A1 (de) * 1991-08-08 1994-07-20 A. Menarini Industrie Farmaceutiche Riunite S.R.L. Zyklische hexapeptide als tachykininantagonisten, verfahren zur herstellung und pharmazeutische zusammensetzungen
IT1262902B (it) 1992-04-15 1996-07-22 Menarini Farma Ind Composti triciclici antagonisti delle tachichinine, loro preparazione e loro uso in composizioni farmaceutiche.
DE19541283A1 (de) * 1995-11-06 1997-05-07 Boehringer Ingelheim Kg Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
IT1291776B1 (it) * 1997-02-07 1999-01-21 Menarini Ricerche Spa Composti monociclici a quattro residui bifunzionali, aventi azione nk-2 antagonista
IT1304888B1 (it) * 1998-08-05 2001-04-05 Menarini Ricerche Spa Composti monociclici ad azione nk-2 antagonista e formulazioni che licontengono

Also Published As

Publication number Publication date
WO2001029066A2 (en) 2001-04-26
AU7919900A (en) 2001-04-30
ES2211628T3 (es) 2004-07-16
US7015196B1 (en) 2006-03-21
ITFI990217A1 (it) 2001-04-21
CA2388315A1 (en) 2001-04-26
EP1224210B1 (de) 2003-12-17
WO2001029066A3 (en) 2001-11-01
CN1382154A (zh) 2002-11-27
DE60007345T2 (de) 2004-11-11
AR026209A1 (es) 2003-01-29
ITFI990217A0 (it) 1999-10-21
EP1224210A2 (de) 2002-07-24
ATE256697T1 (de) 2004-01-15
CN1199987C (zh) 2005-05-04
JP2003512387A (ja) 2003-04-02
IT1307809B1 (it) 2001-11-19
PT1224210E (pt) 2004-04-30

Similar Documents

Publication Publication Date Title
ATE554113T1 (de) Butencopolymere und verfahren zu ihrer herstellung
ATE302754T1 (de) Sulfonylcarboxamidderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE60034683D1 (de) 3(5)-ureido-pyrazolderivate, deren herstellungsverfahren und verwendung als krebshemmende mittel
DE60233058D1 (de) Silsesquioxanderivate und verfahren zu ihrer herstellung
DE60208373D1 (de) Polyaryleneether-polyolefinzusammensetzung, verfahren zu deren herstellung und formassen daraus
ATE490256T1 (de) Neue cyanopyrrolidide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE60217202T8 (de) Polyhydroxyalkanoat-Polyester, die Vinylphenylgruppen in der Seitenkette enthalten, und Verfahren zu ihrer Herstellung
DE60023023T2 (de) Zirkoniumdioxidsol und verfahren zu seiner herstellung
DE60215922D1 (de) Filterelement, verfahren zu seiner herstellung und das element verwendender filter
ATE482193T1 (de) Indolonacetamidderivate, verfahren zu deren herstellung und deren verwendungen
DE50207011D1 (de) Arylisoxazolin-derivative, verfahren zu ihrer herstellung und ihre verwendung als schädlingsbekämpfungsmittel
ATE272634T1 (de) Benzothiophenderivate, verhahren zu ihrer herstellung und ihre verwendung
ATE232879T1 (de) Erythromycin-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
ATE323092T1 (de) Pyridopyrimidinon-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE60226677D1 (de) Saw-einrichtung und verfahren zu ihrer herstellung
ATE337317T1 (de) Imidazopyrin-derivate, verfahren zu ihrer herstellung and sie enthaltende pharmazeutische zusamensetzungen
HK1088922A1 (en) Carbamated polyols, and compositions and methods using the same
DE60007345D1 (de) Basische monocyclische verbindungen mit nk-2 antagonistischer wirkung, verfahren zu ihrer herstellung, und sie enthaltende mittel
IL144370A0 (en) Epothilon derivatives, method for the production and the use thereof as pharmaceuticals
DE60319717D1 (de) Spandexfaser mit ethylendiamin/1,2-diaminopropan als kettenverlängerer und verfahren zu dessen herstellung
ATE294175T1 (de) 4-sulfonamid-piperidin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
DE60010113D1 (de) N-guanidinalkylamide, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische präparate
DE69529467D1 (de) Substituierte pyrazolyl-pyrazol-derivate, verfahren zu ihrer herstellung und ihre verwendung als mittel mit herbizider wirkung
DE60028757D1 (de) Polyolefinzusammensetzung, verfahren zur herstellung und die verwendung davon
DE60123292D1 (de) Uht-milchkonzentratspackung und verfahren zu ihrer herstellung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee